دانلود مقالات ISI درباره Lxr + ترجمه فارسی

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Keywords: Biotransformation; Cytochrome P450 monooxygenase; NADPH:cytochrome P450 reductase; Pharmacogenetics; Polymorphism; Xenobiotic; ADME; absorption, distribution, metabolism, excretion; ADR; adverse drug reaction; AhR; aromatic hydrocarbon receptor; CNV; copy

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2013 سفارش ترجمه

Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages

Keywords: LXR; Platelet; Aggregation; 22(R)-hydroxycholesterol; 22(S)-hydroxycholesterol; BODIPY

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Emerging roles for LXRs and LRH-1 in female reproduction

Keywords: Female reproduction; Cholesterol controlling nuclear receptors; LXR; LRH1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice

Keywords: Metabolic Syndrome; Fatty Liver; NAFLD; Mouse Model; 27HC; 27-hydroxycholesterol (25(R)26 hydroxycholesterol); ALT; alanine aminotransferases; COL1A1; collagenase 1A1; CTX; cerebrotendinous xanthomatosis; HFC; high-fat high cholesterol; IL; interleukin; K

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Sulfated oxysterols as candidates for the treatment of nonalcoholic fatty liver disease

Keywords: 25HC; 25-hydroxycholesterol; 25HC3S; 5-cholesten-3β-25-diol-3-sulfate; HMG; 3-hydroxy-3-methylglutaryl; ChREBP; carbohydrate response element binding protein; LXR; liver X receptor; NAFL; simple nonalcoholic fatty liver; NAFLD; nonalcoholic fatty liver d

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of a new binding mode for a series of liver X receptor agonists

Keywords: LXR; Agonist; Nuclear receptor; SAR; Pyrrole

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Ethyl 2,4,6-trihydroxybenzoate is an agonistic ligand for liver X receptor that induces cholesterol efflux from macrophages without affecting lipid accumulation in HepG2 cells

Keywords: ABC; ATP-binding cassette transporter; FAS; fatty acid synthase; HDL; high-density lipoprotein; LBD; ligand-binding domain; LDL; low-density lipoprotein; LXR; liver X receptor; NPC1L1; Niemann-Pick C1 Like 1; SCD-1; stearoyl-CoA desaturase 1; SPR; surface

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids

Keywords: ApoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A1; CETP; cholesterol ester transfer protein; CHD; coronary heart disease; EPA; eicosapentaenoic acid; HDAC; histone deacetylase; HDL; high-density lipoprotein; HDL-C; HDL cholesterol; LC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Side-chain oxysterols: From cells to membranes to molecules

Keywords: ACAT; acyl-CoA cholesterol acyl transferase; CF; carboxyfluorescein; DOPC; dioleolyphosphatidylcholine; DPPC; dipalmitoylphosphatidylcholine; HC; hydroxycholesterol; LXR; liver X receptor; POPC; 1-palmitoyl-2-oleoyl-phosphatidylcholine; Scap; SREBP cleava

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Retinoid chemistry: Synthesis and application for metabolic disease

Keywords: ROL; retinol; RAL; retinal; RA; retinoic acid; RXR; retinoid X receptor; HWE; Horner-Wadsworth-Emmons; TTNPB; 4-[(1E)-2-(5, 5, 8, 8-tetramethyl-5, 6, 7, 8-tetrahydro-2-naphthalenyl)-1-propen-1-yl]benzoic acid; RAR; retinoic acid receptor; 4-HPR; N-(4-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol

Keywords: ABC; ATP binding cassette; ApoAI; apolipoprotein AI; FPLC; fast protein liquid chromatography; HDL; high density lipoprotein; LXR; liver X receptor; SR-B1; scavenger receptor-1B; SREBP-1c; sterol-regulatory element-binding protein-1c; TICE; transintestina

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7

Keywords: LXR, liver X receptors; miRNA, microRNA; qPCR, quantitative PCR; ABCA1, ATP-binding cassette transporter A1; ARL7, ADP-ribosylation factor-like 7; RCT, reverse cholesterol transport; 3′UTRs, 3′ untranslated regions.MicroRNA; MiR-26; LXR; Cholesterol efflu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1)

Keywords: 24,25EC; 24(S),25-epoxycholesterol; Arg-TLC; argentation thin layer chromatography; CD; methyl-β-cyclodextrin; CHO; Chinese hamster ovary; DOS; 2,3(S):22(S),23-dioxidosqualene; DHCR24; 3β-hydroxysterol ∆24-reductase; FAD; flavin adenine dinucleotide;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Insertion–deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin

Keywords: FADS2; FADS1; Insertion–deletion; Intron; LCPUFA; LXR; Statin; SREBP-1c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease

Keywords: Bile acids; CYP7A1; Fatty liver; FXR; LXR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dancing with the sterols: Critical roles for ABCG1, ABCA1, miRNAs, and nuclear and cell surface receptors in controlling cellular sterol homeostasis

Keywords: ABC; ATP Binding Cassette; AICAR; Aminoimidazole Carboxamide Ribonucleotide; ApoE; Apolipoprotein E; ApoER2; ApoE receptor 2 (LRP8); AR; Androgen Receptor; BAC; Bacterial Artificial Chromosome; CETP; Cholesterol Ester Transfer Protein; eNOS; endothelial N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters

Keywords: PCSK9; LDLR; SREBP; HNF1α; PPARα; LXR; LDL-cholesterol; Fasting; Golden Syrian hamsters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

Keywords: AF1; activation function 1; ANIT; α-naphthylisothiocyanate; AR; androgen receptor; BA; bile acids; BDL; bile duct ligation; ChIP-seq; chromatin immunoprecipitation-sequencing; DBD; DNA binding domain; DR; direct repeat; ER; estrogen receptor; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1

Keywords: Apo-A-I; apoE; ABCA1; LXR; Brain lipid metabolism;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Retinoid metabolism and its effects on the vasculature

Keywords: ADH; alcohol dehydrogenase; ADMA; asymmetric dimethylarginine; AP-1; activated protein-1; apo14; β-apo-14′-carotenal; ARVM; adult rat ventricular myocytes; ATBC; Alpha-tocopherol Beta-carotene Cancer Prevention Study; atRA; all-trans retinoic acid; BCO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Cloning and functional expression of novel cholesterol transporters ABCG1 and ABCG4 in gonadotropin-releasing hormone neurons of the tilapia

Keywords: ABCG transporters; teleost; GnRH; lipid; cholesterol; ABC; ATP-binding cassette; AP; adapter primer; apoE; apolipoprotein E; AUAP; abridged universal amplification primer; BSA; bovine serum albumin; Cb; Cerebellum; cDNA; complementary DNA; dNTP; deoxyribo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages

Keywords: ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; AcLDL; acetylated low-density lipoprotein; apoA-I; apolipoprotein A-I; ATRA; all-trans retinoic acid; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Lipid metabolism in mammalian tissues and its control by retinoic acid

Keywords: ACC; acetyl-coA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; atRA; all-trans retinoic acid; BAT; brown adipose tissue; BCMO1; β,β-carotene monooxygenase 1; C/EBP; CCAAT-enhancer binding protein; CAC; carnitine/acylcarnitine c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice

Keywords: EMT; epithelial-mesenchymal transition; FDR; false discovery rate; FFA; free fatty acids; G6P; glucose-6-phosphotase; GcK; glucokinase; GO; gene ontology; GTT; glucose tolerance test; HDL-C; high-density lipoprotein cholesterol; HFD; high fat diet; HOMA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Sterol-dependent nuclear import of ORP1S promotes LXR regulated trans-activation of apoE

Keywords: ORP1; ORP1S; Oxysterol; LXR; Nuclear import; NLS

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis

Keywords: 7α-OH; 7α-hydroxycholesterol; 7-K; 7-ketocholesterol; 9-ONC; 9-oxononanoyl cholesterol; 15d-PGJ2; 15-deoxy-Δ12,14-prostaglandin J2; α-EPOX; 5α,6α-epoxycholesterol; AP-1; activator protein-1; ARE; antioxidant-responsive element; ATF; activating trans

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Features, Diagnosis, and Treatment of Nonalcoholic Fatty Liver Disease

Keywords: Diagnosis; Epidemiology; Cancer Risk; Mechanisms; ALT; alanine aminotransferase; APOC3; apolipoprotein C3; ARFI; acoustic radiation force impulse elastography; AST; aspartate aminotransferase; ATF6; activating transcription factor-6; AUROC; area under the

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2012 سفارش ترجمه

Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action

Keywords: LE; lipophilic extract; LXR; liver X receptor; LXRE; liver X receptor element; RAR; retinoic acid receptor; RARE; retinoic acid responsive element; RXR; retinoid X receptor; SREBP-1c; sterol regulatory element-binding protein 1c; TTNPB; {(E)-4-[2-(5,6,7,8

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

n−3 Fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice

Keywords: NAFLD; non-alcoholic fatty liver diseases; LXR; liver X receptor; SREBP-1c; sterol regulatory binding protein-1c; KO; knockout; SAT; saturated fat; FA; fatty acid; ALT; alanine aminotrasferase; AST; aspartate aminotrasferase; FAS; fatty acid synthase; FFA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Oxygenated derivatives of cholesterol promote hepatitis B virus gene expression through nuclear receptor LXRα activation

Keywords: HBV; Viral expression; Oxysterol; LXR; SREBP2; Interferon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Homology modeling and functional testing of an ABCA1 mutation causing Tangier disease

Keywords: ABCA1; ATP-binding cassette A1; ApoA-I; apolipoprotein A-I; HDL; high density lipoprotein; LXR; liver X receptor; NBD; nucleotide binding domain; TD; Tangier disease; ABCA1; HDL; Cholesterol efflux; Homology modeling; Tangier disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells

Keywords: Phytosterol; ABC transporter; LXR; Tumor necrosis factor α; Interleukin-6; Interleukin-1β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Docosapentaenoic acid (22:5n-3): A review of its biological effects

Keywords: n-3 Polyunsaturated fatty acids (VLCPUFA); Eicosapentaenoic acid (EPA); Docosapentaenoic acid (DPA); Docosahexaenoic acid (DHA); AA; arachidonic acid; ACC; Acetyl CoA Carboxylase; ALA; alpha linolenic acid; BAE; bovine aortic endothelial cells; ChREBP; ca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Post-translational modification of pregnane x receptor

Keywords: PXR; pregnane x receptor; NR; nuclear receptor; PCN; pregnenalone 16α-carbonitrile; Rif; rifampicin; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenolpyruvate carboxykinase; CYP3A; cytochrome P450 3A; CREs; cyclic AMP response elements; PKA; cyclic AMP-d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

RXRα and LXR activate two promoters in placenta- and tumor-specific expression of PLAC1

Keywords: Promoter; RXR alpha; LXR; Nuclear receptor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Liver X receptors, lipids and their reproductive secrets in the male

Keywords: Testis; Epididymis; Prostate; LXR; Lipids

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleConstitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice

Keywords: CAR; constitutive androstane receptor; TCPOBOP; 3,3′,5,5′-tetrachloro-1,4-bis(pyridyloxy)benzene; HDL; high density lipoproteins; CE; cholesteryl esters; LXR; liver X receptor; Constitutive androstane receptor; TCPOBOP; Bile acids; High density lipopr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Diet-induced Lipid Accumulation in Liver Enhances ATP-binding Cassette Transporter g5/g8 Expression in Bile Canaliculi

Keywords: Abcg5; Abcg8; bile canaliculi; high-calorie diet; Lxr;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

Keywords: Placenta; Oxysterols; 25-Hydroxycholesterol; 7-Ketocholesterol; 22(R)-hydroxycholesterol; Nuclear receptor; LXR; Differentiation; Fusion; Syncytialisation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Changes in adipocyte cell size, gene expression of lipid metabolism markers, and lipolytic responses induced by dietary fish oil replacement in gilthead sea bream (Sparus aurata L.)

Keywords: t10; c12-CLA; trans-10; cis-12 conjugated linoleic acid; 66VO; 66% vegetable oil diet; c9,t11-CLA; cis-9, trans-11 conjugated linoleic acid; BSA; bovine serum albumin; DPM; disintegrations per minute; FO; fish oil; HSI; hepatosomatic index; HSL; hormone-s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleOleuropein attenuates hepatic steatosis induced by high-fat diet in mice

Keywords: NAFLD; non-alcoholic fatty liver disease; TG; triglyceride; FFA; free fatty acid; ALT; alanine aminotransferase; AST; aspartate aminostransferase; LXR; liver X receptor; SREBP-1c; sterol regulatory element-binding protein-1c; PPARγ; peroxisome proliferat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes

Keywords: Perfluoroalkyl acids; PPARA; Metabolic regulation; Species specificity; CAR; PXR; LXR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Synthetic LXR agonist inhibits the development of atherosclerosis in New Zealand White rabbits

Keywords: CETP; Cloning; HDL; LXR; Rabbit; Atherosclerosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation

Keywords: Nuclear receptor; Post-translational modification; SUMO; Metabolism; Inflammation; Acute phase response; Transrepression; LXR; PPAR; LRH-1; N-CoR; SMRT; GPS2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Oxysterols as biomarkers in neurodegenerative diseases

Keywords: LXR; ABC A1; Oxysterols; Dementia; Biomarker

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Liver X receptor activation restores memory in aged AD mice without reducing amyloid

Keywords: LXR; Alzheimer's disease; Cholesterol; T0901317; Amyloid; Apoe; Abca1; Abcg1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Apolipoprotein E: From lipid transport to neurobiology

Keywords: AD; Alzheimer's disease; apo; apolipoprotein; FRET; fluorescence resonance energy transfer; LDL; low-density lipoprotein; NMR; nuclear magnetic resonance; VLDL; very low-density lipoprotein; DMPC; dimyristoylphosphatidylcholine; DPPC; dipalmitoylphospho

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation

Keywords: TUOXXRMLFZBSTB-UHFFFAOYSA-N; JTRRVYQZHXAOGI-UHFFFAOYSA-N; QMDSMBFIKFKGBD-MDZDMXLPSA-N; WPHVYHBQJIXGIJ-UHFFFAOYSA-N; FCSGTZIUJUNGAC-UHFFFAOYSA-N; GKTSXRHLYUJTSU-QHCPKHFHSA-N; SPFSVEKWCKWVLI-DEOSSOPVSA-N; SUHGVDRUULOBLM-ZXVVBBHZSA-N; CPEYWROBUIDLPI-UHFFFAOY

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy

Keywords: ABCA-1/G-1; ATP-binding cassette transporter A-1/G-1; ACAT-1; Acyl-CoA:cholesterol acyltransferase-1; AcLDL; acetylated LDL; ADRP; adipocyte differentiation related protein; ApoE/A-I; apolipoprotein E/A-I; BMMs; bone-marrow derived macrophages; CD; cl

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Quantitative analysis of 3α,6α,24-trihydroxy-24,24-di(trifluoromethyl)-5β-cholane, a potent synthetic steroidal liver X receptor agonist in plasma using liquid chromatography-tandem mass spectrometry

Keywords: LXR; liver X receptor; SRM; selected reaction monitoring; ATI-829; 3α,6α,24-trihydroxy-24,24-di(trifluoromethyl)-5β-cholane; MTBE; methyl tert-butyl ether; Atherosclerosis; Cholanic acid; Pharmacokinetics; Quantitative analysis; Method validation; LCâ€

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه