Keywords: ADHD; Attention-deficit/hyperactivity disorder; BED; Binge-eating disorder; BOLD; Blood-oxygen-level dependent; BMI; Body mass index; BN; Bulimia nervosa; CNS; Central nervous system; DSM 5; Diagnostic and statistical manual of mental disorders, fifth edi
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Keywords: 2-AG; 2-arachidonoylglycerol; Aβ; β-amyloid; GABA; γ-amino butyric acid; AD; Alzheimer's diseases; ALS; amyotrophic lateral sclerosis; AEA; anandamide; EAE; autoimmune encephalomyelitis; BBB; blood brain barrier; CDB; cannabidiol; CB; cannabinoid rec
Keywords: 2-AG; 2-arachidonoylglycerol; AD; atopic dermatitis; AEA; arachidonoylethanolamide; DAGL; diacylglycerol lipase; eCB; endocannabinoid; ECS; endocannabinoid system; EMT; endocannabinoid membrane transporter; FAAH; fatty acid amide hydrolase; LPS; lipopolys
Keywords: Endocannabinoids; FAAH; MAGL; Anandamide uptake blockade; Gastric lesion; Rat;
Keywords: 2-AG; 2-arachidonoylglycerol; AADAC; arylacetamide deacetylase; ABHD5/CGI-58; alpha-beta-hydrolase domain containing 5/comparative gene identification-58; ATGL/ PNPLA2; adipose triglyceride lipase; CE; cholesteryl esters; CES/Ces; carboxylesterase; DG; di
Keywords: AEA; anandamide; 2-AG; 2-arachydonoylglycerol; DAGL; diacylglycerol lipases; ECS; endogenous cannabinoid system; FAAH; fatty acid amide hydrolase; MAGL; monoacylglycerol lipase; NAPE-PLD; N-acyl-phosphatidylethanolamine-selective phospholipase D; OEA; ole
Keywords: Cannabinoid; Endocannabinoid; Pain; FAAH; MAGL; Stress; Stress-induced analgesia; Stress-induced hyperalgesia; mGluR5; mPFC; Amygdala; Cortical control of pain; AA-5-HT (PubChem CID: 10027372); BIA-102474 (PubChem CID: 46831476); JZL184 (PubChem CID: 2502
Keywords: 2-AG; 2-arachidonoyglycerol; AEA; arachidonoylethanolamide; AEs; acylethanolamides; CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; DAGL; diacylglycerol lipase; eCBs; endocannabinoids; ECS; endogenous cannabinoid system; FAAH; fatty acid amide h
Keywords: Carboxyesterase 1; Carboxylesterase 2; Fluorescent substrate; AminoPyridines; AADAC; arylacetamide deacetylase; AChE; acetylcholinesterase; CMNA; cyano(6-methoxynaphthalen-2-yl)methyl acetate (Table 2); ELISA; enzyme-linked immunosorbent assay; FAAH; fatt
Keywords: ATP; adenosine triphosphate; BrP; bromopyruvate; CO2; carbon dioxide; CoA; acetyl-coenzyme A; 2-DG; 2-deoxyglucose; ETC; electron transport chain; FAO; fatty acid oxidation; FAD; flavin adenine dinucleotide; FDG; fluorinated deoxyglucose; FFA; free fatty
Keywords: MAGL; monoacylglycerol lipase; 2AG; 2-arachidonoylglycerol; 2PG; 2-palmitoylglycerol; MD; molecular dynamics; Monoacylglycerol lipase; Lid domain; Molecular dynamics simulations;
Keywords: ABHD5; alpha beta hydrolase domain protein 5; AKAP; A-kinase anchoring protein; ATGL; adipose triglyceride lipase; CMA; chaperone mediated autophagy; DAG; diacylglycerol; DGAT2; acyl-CoA:diacylglycerol acyltransferase 2; FA; fatty acid; hsc70; heat shock
Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APCI; atmospheric pressure chemical ionization; APOE; apolipoprotein E; APP; amyloid precursor protein; APPI; atmospheric pressure photoionization; CE; capillary electrophor
Keywords: AC; adenyl cyclase; AD; Alzheimer's disease; 2-AG; 2-arachidonoylglycerol; ABHD6; α,β hydrolase 6; AEA; arachidonylethanolamide/anandamide; ALS; amyotrophic lateral sclerosis; BBB; blood brain barrier; cAMP; cyclic adenosine monophosphate; CBD; cannabid
Keywords: Traumatic brain injury; Chronic traumatic encephalopathy; Tauopathy; Concussion; Repetitive head injury; 2-AG; 2-arachidonoylglycerol; 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; Ach; acetylcholine; AChEI; acetylcholine esterase inhibitor; AD; Alzheim
Keywords: 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABHD4; α/β-hydrolase domain-containing protein 4; ABHD6; α/β-hydrolase domain-containing protein 6; ABHD12; α/β-hydrolase domain-containing protein 12; AEA; arachidonoylethanolamine; CB1; cannabino
Keywords: 2-AG; 2-arachidonoyl-glycerol; AEA; anandamide; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; DOPAC; 3,4-Dihydroxyphenylacetic acid; DA; dopamine; D2; dopamine receptor subtype 2; ECS; endocannabinoid sys
Keywords: WKY; Wistar Kyoto; SD; Sprague-Dawley; qRT-PCR; quantitative real time polymerase chain reaction; AEA; anandamide; 2-AG; 2-arachidonoylglycerol; MAGL; monoacylglycerol lipase; FAAH; fatty acid amide hydrolase; CB1; cannabinoid receptor 1; SIH; stress-in
Keywords: 2-AG; 2-arachidonyl glycerol; AEA; anandamide; CB; cannabinoid receptor; CBD; cannabidiol; COX-2; cyclooxygenase 2; ERK1/2; extracellular signal-regulated kinase ½; FAAH; fatty acid amide hydrolase; IFN; interferon; IL; interleukin; iNOS; inducible nitri
Keywords: 2-AG; 2-arachidonylglycerol; 2-OG; 2-oxogluteric acid; AEA; N-arachidonoylethanolamide; CB1; cannabinoid type 1 receptor; CB1â/â/CB2â/â; CB1 and CB2 deficient; CB2; cannabinoid type 2 receptor; CK; cytokeratin; DAGLα; diacylglycerol lipase α; DA
Keywords: Reactive nitrogen; Sulfate; Deposition; Stable isotope; Alpine; Bulk precipitation; magl; meters above ground level; masl; meters above sea level; Nr; reactive nitrogen; [X]; concentration of X (where XÂ =Â SO42â, NO3â, etc.); w.m.; weighted mean;
Keywords: 2-AG; 2-arachidonoylglycerol; AEA; N-arachidonylethanolamine anandamide; CB1R; cannabinoid type one receptor; CBG; corticosteroid-binding globulin; CRH; corticotrophin-releasing hormone; eCB; endocannabinoid; ECS; endocannabinoid signaling; epm; elevated
Keywords: DAGLα; diacylglycerol lipase alpha; F344; Fischer 344; FAAH; fatty acid amino hydrolase; LEW; Lewis; LGP; lateral globus pallidus; MAGL; monoacylglycerol lipase; NAcc; nucleus accumbens; NAPE-PLD; N-acyl phosphatidylethanolamine phospholipase D; PFc; pre
Keywords: 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABA; activity-based anorexia; ACC1; acetyl coenzyme-A carboxylase-1; AEA; N-arachidonoylethanolamine; AN; anorexia nervosa; ARC; arcuate nucleus; BBB; blood-brain barrier; BED; binge eating disorder; BN;
Keywords: C1P; ceramide 1-phosphate; DAG; diacylglycerol; DAGL; diacylglycerol lipase; DAPI; 4,6-diamidino-2-phenylindole; DTT; dithiotreitol; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol bis (β-aminoethyl ether)-N,N,Nâ²,Nâ²-tetra acetic acid; G-
Keywords: 2-AG; 2-arachidonyl glycerol; AEA; anandamide; DAGL; diacylglycerol lipase; FAAH; fatty acid amide hydrolase; GPR55; G protein-coupled receptor 55; MAGL; monoacylglycerol lipase; NAPE-PLD; N-acyl phosphatidylethanolamine phospholipase D; OEA; N-oleoyletha
Keywords: FFA; Free fatty acid; QQQ-LC/MS; triple quadrupole liquid chromatography-mass spectrometry; MAGL; monoacylglycerol lipase; PEG; polyethylene glycol; EMT; epithelial-to-mesenchymal transition; SRM; single reaction monitoring; AC; acyl carnitines; PC; phosp
Sacred Maya incense, copal (Protium copal - Burseraceae), has antianxiety effects in animal models
Keywords: EPM; elevated plus maze; CER; conditioned emotional response; SI; social interaction; NOR; novel object recognition; eCB; endocannabinoid; MAGL; monoacyl glyercol lipase; ANOVA; one-way analysis of variance; Protium copal; Incense; Anxiety; Elevated plus
Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration
Keywords: 2-AG; 2-arachidonoylglycerol; 4-HNE; 4-hydroxynonenal; 8-isoPGF2α; F2 -isoprostanes; 8-OHdG; 8-hydroxy-2'-deoxyguanosine; AA; arachidonic acid; AEA; N-arachidonoylethanolamine, anandamide; AM3506; 5-(4-hydroxyphenyl) pentanesulfonyl fluoride; Bach1; ba
Scp-2/Scp-x ablation in Fabp1 null mice differentially impacts hepatic endocannabinoid level depending on dietary fat
Keywords: Mouse; Liver; FABP1; Gene ablation; Endocannabinoid; High fat diet; AEA; n-6 arachidonoylethanolamide (anandamide); 2-AG; 2-arachidonoyl glycerol; ARA; arachidonic acid; CB1; cannabinoid receptor-1; DAGLα; diacylglycerol lipase A; DHA; n-3 docosahexaenoi
Î9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult
Keywords: 2-AG; 2-arachidonoyl glycerol; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; A-Taur; N-arachidonoyl taurine; Cdkn1a; cyclin dependent kinase inhibitor 1A; CER; cerebellum specific for this study; cldn5; claudin 5; CTX; cortex specific for this s
Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis
Keywords: α/β-Hydrolase domain-containing 6 (ABHD6); 2-arachidonoylglycerol (2-AG); Multiple sclerosis (MS); Experimental autoimmune encephalomyelitis (EAE); Cannabinoid CB1 receptor; ABHD6; α/β-Hydrolase domain-containing 6; ABPP; activity based protein profil
Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation
Keywords: JZL184; Rat; Monoacylglycerol lipase (MAGL); Inhibitory avoidance; Fear memory; Behavior; JZL184 [4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester]; MAGL inhibitor; SR141716 [5-(4-chlorophenyl)-1-(2,4-dichlorophen
Endocannabinoid Signaling in Embryonic Neuronal Motility and Cell-Cell Contact - Role of mGluR5 and TRPC3 Channels
Keywords: 2-AG; 2-arachidonoyl glycerol; [Ca2+]i; intracellular free calcium concentration; Afatinib; N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophe
Experimental ischemia/reperfusion model impairs endocannabinoid signaling and Na+/K+ ATPase expression and activity in kidney proximal tubule cells
Keywords: 2-AG; 2-arachidonoylglycerol; AEA; anandamide; AM251; N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxamide; CB1; cannabinoid type-1 receptor; CB2; cannabinoid type-2 receptor; DGL; diacylglycerol lipase; ECS; endoc
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice
Keywords: 2-AG; 2-arachidonoylglycerol; CB1; Cannabinoid receptor subtype 1; CB2; Cannabinoid receptor subtype 2; FAAH; Fatty acid amide hydrolase; JZL184; 4-nitrophenyl-4-[bis(1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylate; JWH-018; Naphthalen-1-yl-
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors
Keywords: Monoacylglycerol lipase inhibitors; MAGL; Cancer; Ketoxime;
Cross-validated stable-isotope dilution GC-MS and LC-MS/MS assays for monoacylglycerol lipase (MAGL) activity by measuring arachidonic acid released from the endocannabinoid 2-arachidonoyl glycerol
Keywords: Arachidonic acid; 2-Arachidonoyl glycerol; Cannabinoid receptors; Deuterium; Endocannabinoids; GC-MS; LC-MS/MS; MAGL; Prostaglandins;
Environmental toxin acrolein alters levels of endogenous lipids, including TRP agonists: A potential mechanism for headache driven by TRPA1 activation
Keywords: 2-AG; 2-arachidonyl glycerol; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; A-GABA; N-arachidonoyl GABA; A-Phe; N-arachidonoyl phenylalanine; A-Ser; N-arachidonoyl serine; A-Taur; N-arachidonoyl taurine; A-Tyr; N-arachidonoyl tyrosine; CER; cere
Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL)
Keywords: MAGL; [11C]MA-PB-1; MJN110; Biodistribution; PET imaging; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; 2-AG; 2-arachidonoyl glycerol; BBB; blood brain barrier; Bmax; enzyme expression; BBr3; boron tribromide; CB1; cannabinoid 1 receptors; CDCl3
BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells
Keywords: Annexin V; FITC-conjugated annexinV; BCA; bicinchoninic acid; BNIP3; Bcl2/adenovirus E1B 19Â kDa protein-interacting protein 3; CBP; CREB-binding protein; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CHIP; chromatin immunoprecipitation; CHOP; CCAAT-en
FAAH inhibition produces antidepressant-like efforts of mice to acute stress via synaptic long-term depression
Keywords: FAAH; fatty acid amide hydrolase; AEA; N-arachidonoylethanolamine; LTD; long-term depression; 2-AG; 2-arachidonoylglycerol; DSI; depolarization-induced suppression of inhibition; DSE; depolarization-induced suppression of excitation; MAGL; monoacylglycero
Cannabinoid receptors and TRPA1 on neuroprotection in a model of retinal ischemia
Keywords: Endocannabinoid; TRP channel; Oxygen glucose deprivation; TRPA1; Retina; Chick; OGD; Oxygen and Glucose Deprivation; CBR; Cannabinoid receptor; TRP; Transient Receptor Potential; LDH; Lactate Dehydrogenase; CNS; Central Nervous System; MO; Mustard Oil; AE
Enhanced anandamide signaling reduces flight behavior elicited by an approaching robo-beetle
Keywords: Panic; Anandamide; URB597; 2-AG; JZL184; Active-fear; Robo-beetle; Inbred mice; 2-AG; 2-arachidonoylglycerol; AEA; anandamide; BMT; beetle mania task; CB1; cannabinoid receptor 1; FAAH; fatty acid amide hydrolase; HAB; high-anxiety behavior; MAGL; monoacy
Endocannabinoid 2-AG and intracellular cannabinoid receptors modulate a low-threshold calcium spike-induced slow depolarizing afterpotential in rat thalamic paraventricular nucleus neurons
Keywords: ACSF; artificial cerebrospinal fluid; CBR; cannabinoid receptor; DAG; diacylglycerol; DAGL; DAG lipase; FAAH; fatty acid amide hydrolase; LTS; low-threshold spike; MAGL; monoacylglycerol lipase; PAP; phosphatic acid phosphohydrolase; PA; phosphatidic acid
The endocannabinoid system and Post Traumatic Stress Disorder (PTSD): From preclinical findings to innovative therapeutic approaches in clinical settings
Keywords: Memory consolidation; Memory retrieval; Memory extinction; Memory of emotionally arousing experiences; Endocannabinoid system; Traumatic stress disorder; URB597; WIN55,212-2; JZL184; FAAH; MAGL; Anandamide; 2-arachidonoylglicerol;
Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain
Keywords: 2-AG; 2-arachidonyl glycerol; 2-LG; 2-linoleoyl glycerol; ABHD4; α/β-hydrolase domain 4; AEA; N-arachidonoyl ethanolamine (anandamide); A-Taur; N-arachidonoyl taurine; CER; cerebellum; COX; cyclooxygenase; CTX; cortex; DEA; N-docosahexaenoyl ethanolamin
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase
Keywords: HPLC–UV; MAGL; 4-Nitrophenylacetate; 4-Nitrophenyldodecanoate; 4-Nitrophenol
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy
Keywords: Neuropathic pain; HIV neuropathy; Allodynia; Antinociception; Endocannabinoid; Gabapentin; HIV; human immunodeficiency virus; HIV-SN; HIV sensory neuropathy; CB; cannabinoidF; AA; fatty acid amide; FAAH; fatty acid amide hydrolase; AEA; anandamide; 2-AG;
Endocannabinoids drive the acquisition of an alternative phenotype in microglia
Keywords: ABDH6; α,β-hydrolase-6; ABDH12; α,β-hydrolase-12; AEA; anandamide; 2-AG; 2-arachidonoylglycerol; Arg-1; Arginase-1; CB1R; cannabinoid receptor 1; CB2R; cannabinoid receptor 2; DAGLs; diacylglycerol lipases; eCBs; endocannabinoids; eCBSS; endocannabino