Keywords: AFib; atrial fibrillation; TSG; tumor suppressor gene; CM; cardiomyocytes; GWAS; genome-wide association studies; SR; sinus rhythm; SNP; small nucleotide polymorphism; ECRG4; esophageal cancer related gene-4; ZFHX3; zinc finger homeobox protein-3; Cx; con
مقالات ISI (ترجمه نشده)
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Keywords: Microbiota; Fructose; Inflammation; Wheat bran; Enterobacteriaceae; AMP; Antimicrobial peptides; AX; Arabinoxylan; CD; Clusters of differentiation; IFN-γ; Interferon gamma; IL; Interleukin; LPS; Lipopolysaccharides; MCP1; Monocyte chemotactic protein 1;
Keywords: BSA; bovine serum albumin; CAECs; carotid artery endothelial cells; DAF; 4-amino-5-methylamino-2â²,7â²-difluorofluorescein diacetate; db/+; non-diabetic control mice; db/db; diabetic mice; db/dbâ¯+â¯SB; strawberry fed diabetic mice; DCFDA; 2â²,7â²-D
Keywords: ERK; extracellular signal regulated kinase; FXR; farsenoid X receptor; HCC; hepatocellular carcinoma; HSCs; hepatic stellate cells; IL1β; Interleukin 1 beta; IL18; Interleukin 18; IKKβ; inhibitor of nuclear factor kappa-B kinase subunit beta; JAK; Janus
Keywords: Ginger; Multiple sclerosis; Experimental autoimmune encephalomyelitis; Therapeutic potentials; AP-1; Activator protein 1; APCs; Antigen-presenting cells; ASC; apoptosis speck-like protein containing CARD; BAFF; B cell-activating factor belonging to the TN
Keywords: Sexual dimorphism; Weight excess; Low-grade chronic inflammation; Cytokines; Chemokines; AUC; area under the curve; BMI; body mass index; E2; total estradiol; hsCRP; high sensitivity C-reactive protein; hsIL-6; high-sensitivity interleukin-6; IL-18; inter
Keywords: AH; alcoholic hepatitis; ALD; alcoholic liver disease; ALT; alanine aminotransferase; CCL; chemokine (C-C motif) ligand; CXCL; chemokine (C-X-C motif) ligand; DAMP; danger-associated molecular pattern; DPI; diphenyleneiodonium; Egr-1; early growth respons
Keywords: 2-DG; 2-deoxy glucose; Akt; protein kinase B; ARDS; acute respiratory distress syndrome; Arg; arginase; BALF; broncho-alveolar lavage fluid; BCG; Bacillus Calmette-Guérin; CD; cluster of differentiation; cGAS; cyclic GMP-AMP synthase; COX-2; cyclooxyge
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Keywords: 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can
Keywords: AR; androgen receptor; qrt-PCR; quantitative real-time PCR; DEGs; Differentially expressed genes; PPI; Protein-protein interaction; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MMPs; matrix metalloproteinases; GO; Gene Ontology; GeneMANIA; The Gene Mu
Keywords: Stenosis; Colitis; Mesenchymal Cells; Epithelial-to-Mesenchymal Transition; αSMA; alpha smooth muscle actin; ATG16L1; autophagy-related 16 like 1; CD; Crohn's disease; CTGF; connective tissue growth factor; DSS; dextran sulfate sodium; ECM; extracellul
Keywords: PPARα; peroxisome proliferator-activated receptor α; AOX; alternative oxidase; ACC; acetyl-CoA carboxylase; SREBP-1c; sterol regulatory element binding protein-1c; DGAT; diacylglycerol O-acyltransferase; ACS; acetyl-CoA synthetase; TNF-α; tumor necrosi
Keywords: HS; hemorrhagic shock; AKI; acute kidney injury; TBSA; total body surface area; GFR; glomerular filtration rate; BUN; blood urea nitrogen; RIFLE; Risk, Injury, Failure, Loss of kidney function, End-stage kidney disease; ADQI; Acute Dialysis Quality Initia
Keywords: ACC; acetyl-CoA carboxylase; ApoB; apolipoprotein B; ApoCII; apolipoprotein C-II; APPL-1; adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and a leucine zipper motif; CD36; fatty acid translocase; CETP; cholesteryl est
Keywords: Liquid chromatography/mass-spectrometry; Non-alcoholic fatty liver disease; Adrenic acid; Chemokine; Alanine aminotransferase; ACOX; acyl Co-A oxidase; ALT; alanine aminotransferase; AC; acylcarnitine; BMI; body mass index; BSA; bovine serum albumin; CDAH
Keywords: Monocyte-Macrophage Precursor Cells; Gastrointestinal Motility; Enteric Nervous System; Interstitial Cells of Cajal; BMP; bone morphogenetic protein; CCR2; C-C chemokine receptor type 2; CD206; mannose receptor C, Type 1 aka MRC1; CSF1; colony-stimulat
Keywords: ACC; acetyl CoA carboxylase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; aspartate transaminase; CRP; C-reactive protein; FAS; fatty acid synthase; HFD; high-fat diet; HMB; β-hydroxy-β-methyl-butyrate
Keywords: ACS; acyl-CoA synthetase; ACSVL; very-long-chain acyl-CoA synthetase; AP; alkaline phosphatase; AST; aspartate aminotransferase; ATF-2; activating transcription factor-2; Bax; Bcl-2 associated X protein; CE; cholesterol ester; Cer; ceramides; CerS; cerami
Keywords: ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; Chk2; checkpoint kinase 2; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DUSP; dual-specificity phosphatase; HIV; human immunodeficiency virus; IL; interleukin; MCP1; monocyte ch
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: CCR2; Human; Immunohistochemistry; Intractable epilepsy; MCP1
Chemokines and cytokines on the neuroimmunoaxis: Inner ear neurotrophic cytokines in development and disease. Prospects for repair?
Keywords: BDNF; brain-derived neurotrophic factor; BMP; bone morphogenetic protein(s) (e.g. BMP2, BMP4 etc.); CNS; central nervous system; CCL2; chemokine (C-C) motif ligand 2 (also called MCP1, monocyte chemoattractant protein 1); CCR2; C-C chemokine receptor type
Prep1 deficiency improves metabolic response in white adipose tissue
Keywords: C/EBP; CCAAT/enhancer binding protein; CD; cluster of differentiation; FABP4; fatty acid binding protein 4; GLUT4; glucose transporter 4; HK1; hexokinase 1; IFNgamma; interferon gamma; IR; insulin receptor; MCP1; monocyte chemotactic protein 1; MIP-1; mac
Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations
Keywords: Asthma; type 2 innate lymphoid cells; IL-33 receptor; thymic stromal lymphopoietin; IL-9; mast cells; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; FoxP3; Forkhead box P3; ICOS; Inducible costimulator; ILC; Innate ly
Maternal Consumption of High-fat Diet in Mice Alters Hypothalamic Notch Pathway, NPY Cell Population and Food Intake in Offspring
Keywords: ARC; arcuate nucleus; Ascl1; achaete-scute homolog 1; bHLH; basic helix-loop-helix; BMP; bone morphogenetic protein; BrDU; 5-bromo-2â²-deoxyuridine; BSA; bovine serum albumin; BW; body weight; Ct; comparative threshold cycle; Cy3; cyanine 3; DAB; 3,3â²-
NADPH oxidase 4 and endothelial nitric oxide synthase contribute to endothelial dysfunction mediated by histone methylations in metabolic memory
Keywords: APO; apocynin; BSP; bisulfite sequencing PCR; ChIP; chromatin immunoprecipitation; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²dichlorodihydrofluorescein diacetate, acetylester; DAF-FM; 4-amino-5-methylamino-2,7-difluorofluorescein diacetate; DANï¼2; 3-d
The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development
Keywords: Mif; jab1; mcp1; Inner ear; Hair cell development; Statoacoustic ganglion; VIII nerve; Zebrafish; Neurotrophic cytokines;
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand
Keywords: CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; LCA; litocholic acid; BAs; bile acids; BARS; bile acid activated receptors; GPBAR1; G protein coupled bile acid receptor; TGR5; Takeda G protein receptor 5; FXR; farnesoid x-receptor; PX
Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways
Keywords: ATG; autophagy-related gene; DMEM; Dulbecco's Modified Eagle Medium; GFP; green fluorescent protein; HFD; high fat diet; Ho-1; heme oxygenase-1; Keap1; Kelch-like ECH-associated protein 1; LC3; microtubule-associated protein 1 light chain 3 (MAP1LC3); MCP
IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies
Keywords: 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r
Emerging role and therapeutic implication of Wnt signaling pathways in liver fibrosis
Keywords: α-SMA; α-smooth muscle actin; ALD; alcoholic liver disease; APC; adenomatous polyposis coli; CamKII; calcium sensitive enzymes calmodulin kinase II; CK1; casein kinase 1; CLD; chronic liver disease; COX-2; cyclooxygenase-2; CTGF; connective tissue growt
Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic
Keywords: Obesity; Chronic low-grade inflammation; Pharmacotherapy; Novel targets; Medicinal plants; Clinical studies; Contents; 5HT2CR; Serotonin receptors subtype 2C; ACC; Acetyl-CoA carboxylase (EC 6.4.1.2); ACTH; Adrenocorticotropic hormone; AgRP; Agouti-relate
Adipogenic miR-27a in adipose tissue upregulates macrophage activation via inhibiting PPARγ of insulin resistance induced by high-fat diet-associated obesity
Keywords: AT; adipose tissue; AUC; area under curve; BW; body weight; HE; hematoxylin and eosin; HFD; high-fat diet; IOD; integral optical density; IR; insulin resistance; ITT; insulin tolerance test; LFD; low-fat diet; MCP1; monocyte chemoattractant protein 1; miR
Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease
Keywords: CD36; DPP4; GLP-1; Insulin resistance; NAFLD; PPARγ; Ad; adenovirus; Akt; Akt serine-threonine protein kinase; ALT; alanine aminotransferase; ApoB; apolipoprotein B; AST; aspartate aminotransferase; BAT; brown adipose tissue; CD36; fatty acid transloca
Esculetin ameliorates insulin resistance and type 2 diabetic nephropathy through reversal of histone H3 acetylation and H2A lysine 119 monoubiquitination
Keywords: RAS; Renin Angiotensin System; T2D; Type 2 Diabetes; T2DN; Type 2 diabetic nephropathy; AT1R; Angiotensin II type-1; AT2R Receptor; Angiotensin II type-2; STZ; Streptozotocin; HFD; High Fat Diet; NPD; Normal Pellet Diet; ECL; Enhanced Chemiluminescence; M
CD44 is a key player in non-alcoholic steatohepatitis
Keywords: CD44; Liver; NAFLD; Steatosis; NASH; MCP1; Macrophages;
Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients
Keywords: Pediatric systemic lupus erythematosus; Mass cytometry; Monocytes; Cytokines; MCP1; Plasma circulating factors; Type I interferons; JAK inhibition; Ruxolitinib; TLR; Toll like receptor; IC; Immune complexes; JAK/STAT; Janus kinase/Signal transducer and ac
Thermogenesis, fatty acid synthesis with oxidation, and inflammation in the brown adipose tissue of ob/ob (â/â) mice
Keywords: AKT; protein kinase B; BAT; brown adipose tissue; beta3-AR; beta 3 adrenergic receptor; BM; body mass; CD36; cluster of differentiation 36; CPT1b; carnitine palmitoyltransferase 1b; EE; energy expenditure; FABP4; fatty acid binding protein 4; FAS; fatty a
Vascular endothelial cell mechanosensing: New insights gained from biomimetic microfluidic models
Keywords: EC; endothelial cell; ECM; extracellular matrix; MFD; microfluidic device; PECAM-1; platelet EC adhesion molecule-1; VE-cadherin; vascular endothelial-cadherin; VEGF; vascular endothelial growth factor; HUVEC; human umbilical vein endothelial cell; HBMEC;
Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic syndrome
Keywords: APC; allophycocyanin; ASC; adipose tissue-derived multipotent mesenchymal cells; BMI; body mass index; CEBPα; CCAAT/enhancer binding protein α; EBM; endothelial basal medium; FBS; fetal bovine serum; FCS; fetal calf serum; FITC; fluorescein isothiocyana
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury
Keywords: Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l
Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance
Keywords: StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine
Nrf2 signaling pathway: Pivotal roles in inflammation
Keywords: ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy
Nanomedicine as a potent strategy in melanoma tumor microenvironment
Keywords: α-SMA; α-smooth muscle actin; MCP1; monocyte chemotactic protein 1; FAP; fibroblast activation protein; PDGF; platelet-derived growth factor; HGF; hepatocyte growth factor; CAPS; cancer associate protease; PLGA; poly (lactic-co-glycolic acid); ESMSVs; e
Protective effects of fish oil and pioglitazone on pancreatic tissue in obese KK mice with type 2 diabetes
Keywords: AQP7; aquaglyceroporin 7; BAP; biological antioxidative potential; CHOP; CCAAT/enhancer-binding protein homologous protein; CT; computed tomography; DHA; docosahexaenoic acid; d-ROMs; diacron of reactive oxygen metabolites; ELISA; enzyme-linked immunosorb
Human adenovirus Ad36 and its E4orf1 gene enhance cellular glucose uptake even in the presence of inflammatory cytokines
Keywords: Glycemic control; MCP1; TNFα; 3T3-L1; Preadipocytes; Adipocytes; MCP; monocyte chemoattractant protein; TNF; tumor necrosis factor; Glut; glucose transporter; LPS; lipopolysaccharides; IR; insulin resistance; IRS; insulin receptor substrates; Ad36; (huma
Combination of n-3 polyunsaturated fatty acids reduces atherogenesis in apolipoprotein E-deficient mice by inhibiting macrophage activation
Keywords: Atherosclerosis; Inflammation; Lipid raft; Macrophage; n-3 poly unsaturated fatty acid; Toll-like receptor 4; Apoeâ/â; apolipoprotein E-deficient; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; LPS; lipopolysaccharide; Mac3; macrophage antigen
Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase
Keywords: ApoEÂ â/â; Â ApoE deficient; DBP; diastolic blood pressure; EETs; epoxyeicosatrienoic acids; H2O2; hydrogen peroxide; ICAM1; intercellular adhesion molecule 1; LCA; left common carotid artery; MAP; mean arterial pressure; MCP1; monocyte chemoattractan