Keywords: ROC; Retina organotypic culture; RPE; retinal pigment epithelium; OLM; outer limiting membrane; OS; outer segment; RGCs; retinal ganglion cells; ONL; outer segment layer; DMEM; Dulbecco's Modified Eagle Medium; PDE6; phosphodiesterase-6; MEF2; myocyte e
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Keywords: AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Arc; activity-regulated cytoskeletal-association protein; BDNF; bone-derived neurotrophic factor; CaMK; Ca2+/calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate;
Keywords: ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a
Keywords: CoA; coenzyme A; TCA; tricarboxylic acid; [Ca2+]i; cytosolic free Ca2+; E-C; excitation-contraction; SR; sarcoplasmic reticulum; SERCA; SR Ca2+-ATPase; AMPK; adenosine monophosphate-activated protein kinase; MEF2; myocyte enhancer factor-2; PPAR; peroxiso
Keywords: ADMA; asymmetric dimethylarginine; cAMP; cyclic adenosine monophosphate; CD73; cluster of differentiation 73; CDC2; cell division cycle 2; CFTR; cystic fibrosis transmembrane conductance regulator; cGMP; cyclic guanosine monophosphate; CH; chronic hypoxia
Keywords: APP; amyloid precursor protein; ATF; activating transcription factor 6; CREB; cAMP response element binding protein; EC; enriched condition; EDTA; ethylenediaminetetraacetic acid; ERK; extracellular signal regulated kinase; FR1; fixed ratio 1; GO; Gene On
Keywords: Aβ; β-Amyloid peptide; Aβ40; 40-amino acid isoform of β-Amyloid peptide; Aβ42; 42-amino acid isoform of β-Amyloid peptide; Aβ42/Aβ40; ratio of measured steady-state levels of Aβ42 and Aβ40; AD; Alzheimer's Disease; AICD; APP intracellular domain
Keywords: MEF2; myocyte-specific enhancer factor 2; MEF2 genes; MEF2A, MEF2B, MEF2C and MEF2D; MC; myocardium; LD; longissimus dorsi; TB; triceps brachii; SM; semimembranosus; Top2β; DNA topoisomerase 2 beta; YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygen
Keywords: Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
Keywords: Histone deacetylases; Histone deacetylases inhibitors; Heart failure; Hypertrophy; DOCA; deoxycorticosterone acetate; HAT; histone acetyltransferases; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; MEF2; myocyte enhancer factor-2; MITR;
Keywords: AKAPs; A-kinase anchoring proteins; AKT; protein kinase b; Ang-II; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BH4; tetrahydrobiopterin; CaMKII; Ca/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CHF; chronic heart fa
Keywords: Activity-dependent transcription; CREB; CRTC1; SRF; MEF2; Npas4; DREAM; Memory; Virus vector;
Keywords: Cyclin-dependent kinase 5; Isoflurane; Apoptosis; Learning and memory; Neurotoxicity; Hippocampus; Calpain; Ca2+-activated protease; CDK5; Cyclin-dependent kinase 5; DIV; Day in vitro; DN CDK5; Dominant-Negative cyclin-dependent kinase 5; FCM; Flow cytom
Keywords: ACAA2; 3-oxoacyl-CoA thiolase; ADIPOR; adiponectin receptor; AF1,2; activation function 1,2; AMPK; AMP-activated protein kinase; ATF4; activating transcription factor 4; ATGL; adipose triglyceride lipase; CaMK; calcium/calmodulin-dependent kinase; CD36; f
The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons
Keywords: Neural stem cells; Neurons; Differentiation; Development; MEF2; Transcription factor;
Characterization of the promoter region of bovine SIX4: Roles of E-box and MyoD in the regulation of basal transcription
Keywords: SIX4 gene; Promoter; MyoD; Ebox; TF; transcription factors; QCMCs; Qinchuan cattle muscle cells; MRFs; myogenic regulatory factors; MEF2; enhancer factor 2; EMSA; electrophoretic mobility shift assay; ChIP; chromatin immunoprecipitation; ORF; open reading
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Keywords: Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon
MEF2A regulates Calpain 3 expression in L6 myoblasts
Keywords: MEF2; myogenic enhancer factor 2; Calpain; calcium-dependent, non-lysosomal cysteine protease; CAPN3; Calpain 3, calcium-dependent, non-lysosomal cysteine protease3; FoxO; Forkhead box O; HEK293; human embryonic kidney cells 293; EMSA; electrophoretic mob
Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop
Keywords: SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge
Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies
Keywords: Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe
Rosiglitazone promotes cardiac hypertrophy and alters chromatin remodeling in isolated cardiomyocytes
Keywords: ANP; atrial natriuretic peptide; BNP; brain natriuretic peptide; CaMKIIδB; calcium-dependent protein kinase IIδB; CM-PGKO; cardiomyocyte-specific PPAR-γ knockout; DMSO; dimethyl sulfoxide; H3; histone H3; Mef2; myocyte enhancer factor-2; p38MAPK; p38 m
Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation
Keywords: Acetylation; GCN5; Mitochondria; SIRT1; Deacetylase; PGC-1α; AMP; adenosine monophosphate; Ca2+; calcium; CBP; CREB-binding protein; Cre-MCK; creatine kinase promoter; CHO; carbohydrate; DAC; deacetylase; ETC; electron transport chain; ExT; endurance exe
GATA5 SUMOylation is indispensable for zebrafish cardiac development
Keywords: WT; wild-type; UBC9; ubiquitin-conjugating enzyme E2I; SAE1/SAE2; SUMO-activating enzyme subunit 1 and 2; PML; promyelocytic leukemia protein; SENP2; sentrin-specific protease 2; SENP5; sentrin-specific protease 5; ASDs; atrial septal defects; VSDs; ventr
Mef2 and the skeletal muscle differentiation program
Keywords: Skeletal muscle development; Mef2; Gene expression network; Differentiation; Regeneration; Alternative splicing; Protein interactions;
BRM promoter insertion polymorphisms increase the risk of cancer: A meta-analysis
Keywords: CNKI; China National Knowledge Infrastructure; HWE; Hardy-Weinberg equilibrium; PA; Pancreatic adenocarcinoma; ESCC; squamous cell carcinoma; HCC; hepatocellular carcinoma; HNSCC; head and neck squamous cell carcinoma; LC; lung cancer; PCR-PAGE; polyacryl
Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors
Keywords: Endothelin-1; Cardiac hypertrophy; Signalling; MAPK; GPCRs; Act D; actinomycin D; Ang II; angiotensin II; ANF; atrial natriuretic factor; BNP; brain natriuretic factor; CN; calcineurin; CVD; cardiovascular disease; ara-C; cytosine b-d-arabinofuranoside; D
Myocardin: A novel player in atherosclerosis
Keywords: Myocardin; Atherosclerosis; Inflammation; Lipid metabolism; VSMC; Abca1; MYOCD; Myocardin; AS; atherosclerosis; SRF; serum response factor; VSMC; vascular smooth muscle cell; Mrtf-A/B; Myocardin-related transcription factors A/B; Mamstr; Mef2-activating S
DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion
Keywords: DDIAS; DNA damage induced apoptosis suppressor; EGF; epidermal growth factor; MEK5; mitogen-activated protein kinase kinase; ERK5; extracellular signal-regulated kinase 5; MEF2; myocyte enhancer factor 2; hNoxin; human noxin; NFAT; nuclear factor of activ
Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression
Keywords: Cx36.7; connexin 36.7; NKX2; NK2 transcription factor; MEF2; myocyte enhancer factor 2; CHD; congenital heart disease; hpf; hours post-fertilization; EGFP; enhanced green fluorescent protein; RLM-RACE; RNA-ligase mediated rapid amplification of cDNA ends;
ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus
Keywords: BrdU; 5-bromo-2â²-deoxyuridine; CORT; corticosterone; DAB; 2,2-diaminobenzidine; DG; dentate gyrus; GR; glucocorticoid receptors; Isx-9; isoxazole 9; Mef2; myocyte enhancer factor-2; MR; mineralocorticoid receptors; NHS; normal horse serum; PFA; paraform
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin
Keywords: gCl; chloride conductance; PKC; protein kinase C; CN; calcineurin; restCa; resting intracellular calcium; MEF2; Myocyte enhancer factor-2; EDL; extensor digitorum longus; CK; creatin kinase; AMPK; AMP-activated kinase; Ion channels; Protein kinase C; Sene
Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production
Keywords: Oxidative phosphorylation (OXPHOS); Mitochondria; miR-23; ERK5; MEF2; Antioxidant response elements (ARE)
Muscle-specific microRNAs in skeletal muscle development
Keywords: HDAC4; histone deacetylase 4; MEF2; myocyte enhancer factor 2; miRNA; microRNA; MRFs; myogenic regulatory factors; MYF5; myogenic factor 5; MYF6; myogenic factor 6 (herculin); MYH6; myosin, heavy chain 6, cardiac muscle, alpha; MYH7; myosin, heavy chain 7
Cdk5/p25 specific inhibitory peptide TFP5 rescues the loss of dopaminergic neurons in a sub-acute MPTP induced PD mouse model
Keywords: Parkinson's disease; MPTP; Cyclin-dependent kinase 5; TFP5; Dopaminergic neurons; MEF2;
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
Keywords: ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr
Tyrosine phosphorylation of RACK1 triggers cardiomyocyte hypertrophy by regulating the interaction between p300 and GATA4
Keywords: ANF; atrial natriuretic factor; β-MHC; β-myosin heavy chain; BNP; B-type natriuretic peptide; CDK9; cyclin dependent kinase 9; ET-1; endothelin-1; FOG2; Friend of GATA 2; GATA4; GATA binding protein 4; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GS
Transcriptional profiling of MEF2-regulated genes in human neural progenitor cells derived from embryonic stem cells
Keywords: MEF2; Transcription factor; Microarray; Gene expression; Human neural stem cells; Neuronal differentiation
S-Nitrosylation in neurogenesis and neuronal development
Keywords: Nitric oxide; Redox signaling; S-Nitrosylation; CREB; MEF2; Neurodevelopmental disorder
Identification of singles bar as a direct transcriptional target of Drosophila Myocyte enhancer factor-2 and a regulator of adult myoblast fusion
Keywords: Drosophila; Myoblast fusion; MEF2; Transcriptional regulation; MARVEL domain; Singles bar
The myogenic repressor gene Holes in muscles is a direct transcriptional target of Twist and Tinman in the Drosophila embryonic mesoderm
Keywords: Drosophila; Myogenesis; Twist; Tinman; Myocyte enhancer factor-2; MEF2; Mesoderm; Transcriptional regulation; Regulatory network;
Epigenetics and muscle dysfunction in chronic obstructive pulmonary disease
Keywords: ANOVA; Analysis of variance; COPD; chronic obstructive pulmonary disease; MyHC; myosin heavy chain; CH3; methyl group; coA; coenzyme A; CpG; cytosine and guanosine nucleotides; DNA; deoxyribonucleic acid; HSP; heat shock proteins; HTAs; histone acetyltran
UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy
Keywords: PDEs; phosphodiesterases; AKAP; A-kinase anchoring protein; cAMP; 3â²,5â²-cyclic monophosphate; Epac; exchange protein directly activated by cAMP; PKA; protein kinase A; PKC; protein kinase C; PKD; protein kinase D; UCR; upstream conserved region; β-AR
Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5
Keywords: 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; AMPK; AMP-activated protein kinase; CPT-cAMP; 8-(4-chlorophenylthio)-cAMP; CREB; cyclic AMP-responsive element-binding protein; CRTC2; CREB regulated transcription coactivator-2; ChIP;
An overview of microRNAs
Keywords: RISC; RNA induced silencing complex; MCM7; Minichromosome maintenance protein 7; DGCR8; DiGeorge syndrome critical region 8; TRBP; TAR RNA binding protein; NGS; Next generation sequencing; C3PO; Component 3 promoter of RISC; TNRC6; Trinucleotide repeat co
The calcineurin antagonist RCAN1-4 is induced by exhaustive exercise in rat skeletal muscle
Keywords: DSCR1; Down syndrome critical region gene 1; EDL; extensor digitorum longus; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,Nâ²,Nâ²- tetraacetic acid; GPx; glutathione peroxidase; HSC70; heat shock 72Â kDa; HP; h
Histone deacetylases in cardiac fibrosis: Current perspectives for therapy
Keywords: HDACs; Histone deacetylases; ECM; Extracellular matrix; α-SMA; α-smooth muscle actin; HATs; Histone acetyltransferases; TGF-β1; Transforming growth factor β1; PDGF; Platelet-derived growth factor; FGF; Fibroblast growth factor; TIMPs; Tissue inhibitor
Reversine induces multipotency of lineage-committed cells through epigenetic silencing of miR-133a
Keywords: ADM; adipogenic differentiation medium; ALP; alkaline phosphatase; miRNA; microRNA; MEF2; myocyte enhancer factor 2; MRF; muscle regulatory factor; ODM; osteogenic differentiation medium; Pol II; RNA polymerase II; SRF; serum response factor; Reversine; m
Insulin acutely triggers transcription of Slc2a4 gene: Participation of the AT-rich, E-box and NFKB-binding sites
Keywords: GLUT4; Skeletal muscle; PI3K/AKT; MEF2; HIF1A; MYOD1
Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb
Keywords: AS; Alternative Splicing; MEF2; Myocyte Enhancer Factor 2; BMP; Bone Morphogenetic Protein; MADS; Minichromosome maintenance, Agamous, Deficiens, Serum response factor; TAD; transcription activating domains; PKA; Protein Kinase A; qRTPCR; quantitative Rea
Adipose induces myoblast differentiation and mediates TNFα-regulated myogenesis
Keywords: Adp; Adipose; C/EBP; CCAAT-enhancer-binding protein; CREB; cAMP-responsive element binding protein; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HDAC; histone deacetylase; KLFs; Krüppel-like transcription factors; KRE; KLF15 response element; MEF2; m