دانلود مقالات ISI درباره تعمیر ناسازگاری + ترجمه فارسی

Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword

Keywords: تعمیر ناسازگاری; DNA methylation; DNA demethylation; Deamination; TET proteins; TDG; Base excision repair; Mismatch repair

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Deposition of histone H2A.Z by the SWR-C remodeling enzyme prevents genome instability

Keywords: تعمیر ناسازگاری; Chromatin remodeling; Genome instability; Mismatch repair; Exonuclease 1; H2A.Z;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Mismatch repair-dependent metabolism of O6-methylguanine-containing DNA in Xenopus laevis egg extracts

Keywords: تعمیر ناسازگاری; DNA damage signaling; DNA replication; O6-methylguanine; Mismatch repair; SN1-type alkylating agents; Xenopus laevis egg extracts

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Insights from a decade of biophysical studies on MutL: Roles in strand discrimination and mismatch removal

Keywords: تعمیر ناسازگاری; Mismatch repair; Lynch syndrome; MutL; Sequence-unspecific nucleases; Processivity sliding clamp and PCNA binding partners; MMR; mismatch repair; MSI; microsatellite instability; MLH; MutL homolog; PMS; post-meiotic segregation; IDL; insertion/deletion lo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

DNA mismatch repair enzymes: Genetic defects and autoimmunity

Keywords: تعمیر ناسازگاری; AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

DNA excision repair at telomeres

Keywords: تعمیر ناسازگاری; Telomere; Base excision repair; Nucleotide excision repair; Mismatch repair; Genome stability

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Chromatographic isolation of the functionally active MutS protein covalently linked to deoxyribonucleic acid

Keywords: تعمیر ناسازگاری; Mismatch repair; MutS protein; DNA-protein crosslinking; Anion exchange chromatography;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Update on immunohistochemistry to identify colorectal tumours with deficient DNA mismatch repair function

Keywords: تعمیر ناسازگاری; BRAF; EpCAM; immunohistochemistry; Lynch syndrome; Lynch-like syndrome; mismatch repair

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The Repeat Expansion Diseases: The dark side of DNA repair

Keywords: تعمیر ناسازگاری; Repeat Expansion Diseases; Mismatch repair; Base excision repair; Transcription coupled repair; Global genome repair; Oxidative damage

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms

Keywords: تعمیر ناسازگاری; CaSR; calcium sensing receptor; CRP; C-reactive protein; ELISA; enzyme-linked immunoassay; 8-OH-dG; 8-hydroxy-deoxyguanosine; IL; interleukin; MMR; mismatch repair; RONS; reactive oxygen and nitrogen species; TGF; transforming growth factor; VDR; vitamin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

Keywords: تعمیر ناسازگاری; FISH; Topoisomerase 1; Topoisomerase 2A; MMR; Chromosomal instability; Gene copy number; TOP1; gene symbol for the gene encoding topoisomerase 1; TOP2A; gene symbol for the gene encoding topoisomerase 2 alpha; CEN17; symbol for the chromosomal region enco

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

Keywords: تعمیر ناسازگاری; ApG; adenine-guanine; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3 related kinase; Bax; Bcl2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; EdU; 5-ethynyl-2′-deoxyuridine; CarboPt; carboplatin; CENP-F; centromere protein F; Chk1; checkpoint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Cell cycle regulation of human DNA repair and chromatin remodeling genes

Keywords: تعمیر ناسازگاری; MMR; mismatch repair; NER; nucleotide excision repair; BER; base excision repair; DSB; DNA double-strand break; NHEJ; non-homologous end joining; HR; homologous recombination; FA; Fanconi anemia; SS; serum starvation; TT; double thymidine block; NZ; nocod

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Cadmium treatment suppresses DNA polymerase δ catalytic subunit gene expression by acting on the p53 and Sp1 regulatory axis

Keywords: تعمیر ناسازگاری; AP; abasic site; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; Cd; cadmium; CNS; central nervous system; DNA LigI; DNA ligase I; MMS; methyl methanesulfonate; OGG1; 8-oxoguanine DNA glycosylase; Polβ; DNA polymerase β; Polδ; po

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular epidemiology and genomics of group A Streptococcus

Keywords: تعمیر ناسازگاری; AGR; accessory gene region; C4BP; C4b-binding protein; Cas; CRISPR-associated proteins; CC; clonal complex; CGH; comparative genomic hybridization; CRISPR; clustered, regularly interspaced short palindromic repeat; D; genetic diversity; DNase; deoxyribonu

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

Genomic Instability Causes HGF Gene Activation in Colon Cancer Cells, Promoting Their Resistance to Necroptosis

Keywords: تعمیر ناسازگاری; Signal Transduction; Receptor Tyrosine Kinase; Oncogene; Gene Regulation; CRC; colorectal carcinoma; DATE; deoxyadenosine tract element; HGF; hepatocyte growth factor; MMR; mismatch repair; MSI; microsatellite instability; MSS; microsatellite stable;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing

Keywords: تعمیر ناسازگاری; CRISPR; clustered regularly interspaced short palindromic repeat; PAM; protospacer adjacent motif; gRNA; guide RNA; DSB; double strand break; ORF; open reading frame; MMR; mismatch repair; MEP; methylerythritol-phosphate; ssDNA; single-strand DNA; dsDNA;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer

Keywords: تعمیر ناسازگاری; Genomic Instability; Microsatellite Instability; Chromosomal Instability; CIMP; ACF; aberrant crypt focus; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; Cox-2; cyclo-oxygenase-2; CRC; colorectal cancer; EGFR; epithelial growth facto

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2015 سفارش ترجمه

High prevalence of deficient mismatch repair phenotype and the V600E BRAF mutation in elderly patients with colorectal cancer

Keywords: تعمیر ناسازگاری; The elderly; Mismatch repair; Colorectal cancer; Carcinogenesis; BRAF

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

A rare MSH2 mutation causes defective binding to hMSH6, normal hMSH2 staining, and loss of hMSH6 at advanced cancer stage

Keywords: تعمیر ناسازگاری; Lynch syndrome; Mismatch repair; MSH2; MSH6; Second hit; Variants of unknown significance

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Keywords: تعمیر ناسازگاری; Family history; Endometrial cancer; Colorectal cancer; Lynch syndrome; Mismatch repair;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Development of DNA mismatch repair gene, MutS, as a diagnostic marker for detection and phylogenetic analysis of algal Megaviruses

Keywords: تعمیر ناسازگاری; Megaviridae; Diagnostic marker; Ocean; Microalgae; MutS; Mismatch repair;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Exploiting DNA mismatch repair deficiency as a therapeutic strategy

Keywords: تعمیر ناسازگاری; Mismatch repair; Synthetic lethality; Drug resistance; Therapeutics;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Microsatellite instability, promoter methylation and protein expression of the DNA mismatch repair genes in epithelial ovarian cancer

Keywords: تعمیر ناسازگاری; EOC; epithelial ovarian cancer; IHC; immunohistochemistry; LOH; loss of heterozygosity; LMP; low malignant potential; MSP; methylation specific PCR; MMR; mismatch repair; MSI; microsatellite instability; MSI-H; microsatellite instability - high; MSI-L;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DR-GAS: A database of functional genetic variants and their phosphorylation states in human DNA repair systems

Keywords: تعمیر ناسازگاری; GAS; Haplotype; nsSNP; LD; Phosphorylation; BER; base excision repair; NER; nucleotide excision repair; MMR; mismatch repair; HRR; homologous recombination repair; NHEJ; non-homologous end joining; TLS; trans lesion synthesis; DDS; DNA damage signaling; H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Emerging importance of mismatch repair components including UvrD helicase and their cross-talk with the development of drug resistance in malaria parasite

Keywords: تعمیر ناسازگاری; Drug resistance; DNA repair; Mismatch repair; Plasmodium falciparum; UvrD;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Exo1 independent DNA mismatch repair involves multiple compensatory nucleases

Keywords: تعمیر ناسازگاری; Mismatch repair; Exonuclease 1; Temozolomide; DNA repair

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer

Keywords: تعمیر ناسازگاری; ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Single molecule studies of DNA mismatch repair

Keywords: تعمیر ناسازگاری; Mismatch repair; One-dimensional diffusion; Single-molecule fluorescence; FRET; Atomic force microscopy; AFM; Single particle tracking; Protein-DNA interactions;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts

Keywords: تعمیر ناسازگاری; εA; 1,N6-ethenoadenine; εC; 3,N4-ethenocytosine; BεC; butanone-ethenocytosine; BεG; butanone-ethenoguanine; BER; base excision repair; CAA; chloroacetaldehyde; 5-FU; 5-fluorouracil; HεC; heptanone-ethenocytosine; HεG; heptanone-ethenoguanine; HEC; 3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Patients With Colorectal Tumors With Microsatellite Instability and Large Deletions in HSP110 T17 Have Improved Response to 5-Fluorouracil-Based Chemotherapy

Keywords: تعمیر ناسازگاری; Therapeutic Response; Prognostic Factor; Outcome; Treatment; CRC; colorectal cancer; DT; deletion status; EBV; Epstein-Barr Virus; 5-FU; 5-fluorouracil; HSP; heat shock protein; MMR; mismatch repair; mRNA; messenger RNA; MSI; microsatellite instability; M

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

ATP binding and hydrolysis by Saccharomyces cerevisiae Msh2–Msh3 are differentially modulated by mismatch and double-strand break repair DNA substrates

Keywords: تعمیر ناسازگاری; Mismatch repair; Double-strand break repair; Msh2–Msh3; ATP binding/hydrolysis; 3′ non-homologous tail removal

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Temozolomide Increases the Number of Mismatch Repair-Deficient Intestinal Crypts and Accelerates Tumorigenesis in a Mouse Model of Lynch Syndrome

Keywords: تعمیر ناسازگاری; Defective Mismatch Repair; Carcinogen; Cancer Risk; Dietary Factors; DMH; 1,2-dimethylhydrazine; LS; Lynch syndrome; MMR; mismatch repair; PCR; polymerase chain reaction; TMZ; temozolomide;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

DNA Testing and Molecular Screening for Colon Cancer

Keywords: تعمیر ناسازگاری; Genetics; Heredity; Colon Cancer; Fecal DNA Test; Polyposis; CLIA; Clinical Laboratories Improvement Act; CRC; colorectal cancer; EGFR; epidermal growth factor receptor; FIT; fecal immunochemical test; FOBT; fecal occult blood test; MMR; mismatch repair;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Visualizing protein movement on DNA at the single-molecule level using DNA curtains

Keywords: تعمیر ناسازگاری; DNA curtains; Diffusion; Translocation; Mismatch repair; RecBCD; Homologous recombination; FtsK; Chromosome segregation;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Single nucleotide polymorphism in hMLH1 promoter and risk of tobacco-related oral carcinoma in high-risk Asian Indians

Keywords: تعمیر ناسازگاری; hMLH1; human MutL homolog 1; MMR; mismatch repair; SNP; single nucleotide polymorphism; OSCC; oral squamous cell carcinoma; PCR-RFLP; polymerase chain reaction-restriction fragment length polymorphism; BPDE; benzo(a)pyrene diol epoxide; DRC; DNA repair ca

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting DNA damage response: Threshold, chromatin landscape and beyond

Keywords: تعمیر ناسازگاری; DSBs; double strand breaks; γ-H2AX; phosphorylation of histone variant H2AX in Ser139; SUMO; small ubiquitin modifier; ROS; reactive oxygen species; IR; ionizing radiation; Tip60; Tat-interactive 60; HAT; histone acetyltransferase; HDAC; histone deacetyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Multiple microRNAs may regulate the DNA repair enzyme uracil-DNA glycosylase

Keywords: تعمیر ناسازگاری; 3′UTR; 3′untranslated region; AID; activation-induced cytidine deaminase; ATM; mutated in ataxia teleangiectasia; BER; base excision repair; CLL; chronic lymphocytic leukemia; CSR; class-switch recombination; miRNA; microRNA; MMR; mismatch repair; NER

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The mismatch repair gene hPMS1 (human postmeiotic segregation1) is down regulated in oral squamous cell carcinoma

Keywords: تعمیر ناسازگاری; hPMS1; human postmeiotic segregation1; MSI; microsatellite instability; OSCC; oral squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; MMR; mismatch repair; RER +; replication error; IHC; immunohistochemistry; GDB; genome database; AEC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of chromosomal copy number variations and novel candidate loci in hereditary nonpolyposis colorectal cancer with mismatch repair proficiency

Keywords: تعمیر ناسازگاری; HNPCC; hereditary non-polyposis colorectal cancers; MMR; mismatch repair; MSS; microsatellite stable; MSI; microsatellite instability; CNV; copy number variation; LOH; loss of heterozygosity; cnLOH; copy-neutral loss of heterozygosity; qPCR; quantitative

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Mismatch recognition function of Arabidopsis thaliana MutSγ

Keywords: تعمیر ناسازگاری; Mismatch repair; Genome stability; Mutation rate; Arabidopsis thaliana; Saccharomyces cerevisiae;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis

Keywords: تعمیر ناسازگاری; AP; apurinic/apyrimidinic; ARE; antioxidant response element; ATM; ataxia telangiectasia mutated kinase; ATR; Rad3-related kinase; BER; base excision repair; FEN1; flap endonuclease 1; HD; Huntington's disease; MMR; mismatch repair; Nrf2; NF-E2-related

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates

Keywords: تعمیر ناسازگاری; Transformation; Mismatch repair; Recombination; Methylation; Nucleotide excision repair; Base excision repair;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Association between the XRCC3 T241M polymorphism and risk of cancer: Evidence from 157 case-control studies

Keywords: تعمیر ناسازگاری; XRCC3; the X-ray repair cross-complementing group 3; OR; odds ratios; CIs; confidence intervals; BER; base excision repair; NER; nucleotide excision repair; DSBR; double-strand break repair; MMR; mismatch repair; HWE; Hardy-Weinberg equilibrium; HRR; ho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cells

Keywords: تعمیر ناسازگاری; QDs; quantum dots; ZFL; zebrafish liver cells; ROS; reactive oxygen species; BER; base excision repair; NER; nucleotide excision repair; MMR; mismatch repair; NHEJ; non-homologous end joining; Cd; cadmium; CdTe; cadmium telluride; MPA; mercaptopropionic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells

Keywords: تعمیر ناسازگاری; AP-1; activator protein; BER; base excision repair; CDK; cyclin-dependant kinase; CDKI; cyclin-dependant kinase inhibitor; CYN; cylindrospermopsin; CYP450; cytochrome P450; DSB; DNA double-strand break; ER; endoplasmic reticulum; GST; glutathione S-transf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DNA repair mechanisms in dividing and non-dividing cells

Keywords: تعمیر ناسازگاری; DNA repair; Neural cells; Neurological disorder; Dividing and non-dividing; Endogenous DNA damage; AOA1; ataxia with ocular motor apraxia 1; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; APTX; aprataxin; ATM; ataxia telangiectasia mutated; CPDs; cyc

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth)

Keywords: تعمیر ناسازگاری; BER; base excision repair; BG; O6-benzylguanine; Mx; methoxyamine; MMS; methyl methanesulfonate; MMR; mismatch repair; MNU; N-methyl-N-nitrosourea; MPG; N-methylpurine-DNA glycosylase; O6meG; O6-methylguanine; MGMT; O6-methylguanine-DNA methyltransferase;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2013 سفارش ترجمه

Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α

Keywords: تعمیر ناسازگاری; Exo1; Mismatch repair; Genome stability; Replication fidelity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth

Keywords: تعمیر ناسازگاری; microRNA; Lung cancer; MSH2; Cisplatin; Gene expression; miRNAs; microRNAs; MMR; mismatch repair; 3′-UTR; 3′-untranslated region; hMSH2; Human mutS homolog 2; hMLH1; human mutL homolog 1; nt; nucleotides; FACS; Flow cytometry; RT-PCR; Reverse transcri

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه