Keywords: Fatal thyroid cancer; Genetics; MET; MLH1; PDGFRA;
مقالات ISI (ترجمه نشده)
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Keywords: Colorectal Cancer; Microsatellite Instability; Tumorigenic Process; Driver Gene Mutations; Positive and Negative Selection; bp; base pair; CRC; colorectal cancer; HR; hazard ratio; indel; insertion/deletion; MLH1; MutL Homolog 1; MMR; mismatch repair; mRN
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: cutaneous T-cell lymphoma; hereditary nonpolyposis colon cancer; Lynch syndrome; microsatellite instability; MLH1; Muir-Torre syndrome; MSH2; mycosis fungoides; ECP; extracorporeal photopheresis; HNPCC; hereditary nonpolyposis colorectal carcinoma; ICL; i
Keywords: MMR mutations; Lynch syndrome; Hispanics; MLH1; MSH2; MSH6; PMS2; colon cancer;
Keywords: AC; Amsterdam criteria; AFAP; attenuated familial adenomatous polyposis; APC; adenomatous polyposis coli; CAP; College of American Pathologists; CD; Crohn disease; CLIA; Clinical Laboratory Improvement Amendments; CRC; colorectal cancer; dMMR; deficient m
Keywords: Aza; 5-aza 2 deoxycytidine; TSA; trichostatin A; MeCP2; methyl CpG binding protein 2; SLE; systemic lupus erythematosus; RA; rheumatoid arthritis; DNMTs; DNA methyltransferases; HDACs; histone deacetylases; HAT; histones acetyl transferases; HMT; histone
Keywords: 11KT; 11-ketotestosterone; 17bhsd; 17β-hydroxysteroid dehydrogenase; 17P; 17α-hydroxyprogesterone; 17,20bP; 17,20β-dihydroxy-4-pregnen-3-one; 20b-HSD; 20β-hydroxysteroid dehydrogenase; 20βS; 17,20β,21-trihydroxy-4-pregnen-3-one; actRIIB; activin rec
Keywords: Mismatch repair; Castration resistant prostate cancer; MLH1; MSH2; MSH6; PMS2;
Keywords: LS; Lynch syndrome; CRC; colorectal cancer; HNPCC; hereditary non-polyposis colon cancer; MMR; mismatch repair; FAP; familial adenomatous polyposis; CFS; cancer family syndrome; MSI; microsatellite instability; IDL; insertion/deletion loop; MSH2; human mu
Keywords: Bloom syndrome; dyskeratosis congenita; genetic testing; Gorlin syndrome; Muir-Torre syndrome; nonmelanoma skin cancer; oculocutaneous albinism; Rothmund-Thomson syndrome; Werner syndrome; 5-FU; 5-fluorouracil; ADA1; adenosine deaminase 1; ADA-SCID; a
Keywords: MMR; mismatch repair; MSH; mutS homolog; MLH; mutL homolog; BER; base excision repair; NER; nucleotide excision repair; TNR; trinucleotide repeat; DM1; myotonic dystrophy type 1; HD; huntington's disease; FRDA; Friedreich's ataxia; FXD; fragile X dise
Keywords: AAV4; adeno-associated virus serotype 4; BDNF; brain-derived neurotrophic factor; bFGF; fibroblast growth factor 2; BME; β-mercaptoethanol; BMP; bone morphogenetic protein; Cas9; CRISPR associated protein 9; Cla; claustrum; CN; caudate nucleus; CRISPR; c
Keywords: Lynch Syndrome; microsatellite instability; mismatch repair deficiency; MLH1; MSH2; MSH6; PMS2;
Keywords: ABCB1; ATP-Binding Cassette, Sub-Family B; MDR; Multi Drug Resistance; DAPK; Death Associated Protein Kinase; APAF-1; Apoptotic Peptidase Activating Factor 1; MLH1; MutL Homolog 1; MGMT; O-6-Methylguanine-DNA Methyltransferase; KDM5A; Lysine (K)-Specific
Keywords: Constitutional mismatch repair deficiency syndrome; MLH1; MSH2; PMS2; MSH6; Microsatellite instability
Keywords: AIN; AIN-93G purified diet for laboratory rodents; CRC; colorectal cancer; 2D DIGE; two-dimensional differential gel electrophoresis; FAO; fatty acid oxidation; GO; Gene Ontology; LS; Lynch syndrome; MLH1; MutL homolog 1; MMR; mismatch repair; PPP; pentos
Keywords: AID; activation-induced cytidine deaminase; H. pylori; Helicobacter pylori; IARC; International Agency for Research on Cancer; GI; gastrointestinal; CI; confidence interval; KLF5; Krüppel-like factor 5; VCP; valosin-containing protein; OLGA; Operative Li
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer
Keywords: DDR; DNA Damage Response; IBD; Inflammatory Bowel Disease; CAC; Colitis-Associated Cancer; MSI; microsatellite instability; AOM; Azoxymethane; DSS; Dextran sodium sulfate; HMSL; high magnification surgical lenses; MVT; macroscopically visible tumor; NMVT;
Novel minor HLA DR associated antigens in type 1 diabetes
Keywords: IM; Inflammatory myositis; MLH1; MutL homolog; MTIF3; Mitochondrial translational initiation factor 3; NAPPA Array; Nucleic acid programmable protein arrays; NUP50; Nucleoporin 50; PD-1; Programmed cell death protein 1; PDL1; Programmed cell death 1 ligan
The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences
Keywords: MLH1; ATPase; Interstitial telomere sequences;
Cell cycle arrest mediated by Cd-induced DNA damage in Arabidopsis root tips
Keywords: CDKs; Cyclin-dependent kinases; CYCB1;1; Cyclin B1;1; qRT-PCR; Real time quantitative reverse transcription-polymerase chain reaction; BRCA1; Breast cancer susceptibility1; PCNA; Proliferation cell nuclear antigen; DSB; Double strand break; GR1; Gamma res
Overexpression of MutL homolog 1 and MutS homolog 2 proteins have reversed prognostic implications for stage I-II colon cancer patients
Keywords: Colon cancer; MLH1; MSH2; CEA; Mismatch repair;
Methylation analysis of DNA repair genes in Alzheimer's disease
Keywords: DNA methylation; Alzheimer's disease; Epigenetics; DNA repair; OGG1; PARP1 BRCA1; MGMT; MLH1; MRE11A;
Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma
Keywords: Signal Transduction; Metabolism; Tumorigenesis; Colon Cancer; AAL; Aleuria aurantia lectin; CRC; colorectal cancer; FITC; fluorescein isothiocyanate; FX; guanosine diphosphate-4-keto-6-deoxymannose 3,5-epimerase-4-reductase; GDP; guanosine diphosphate;
Mouse models of DNA mismatch repair in cancer research
Keywords: Mouse models; DNA mismatch repair; Msh2; Mlh1; Hereditary non-polyposis colon cancer; Lynch syndrome;
Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations
Keywords: Lynch syndrome; Constitutional Mismatch Repair Deficiency syndrome; clinic; DNA Mismatch repair; MLH1; MSH2; PMS2; MSH6; review;
SOX9 expression predicts relapse of stage II colon cancer patients
Keywords: dMMR; mismatch repair deficiency; IHC; immunohistochemistry; MLH1; MutL homolog 1; MMR; mismatch repair; MSH2; MutS protein homolog 2; MSH6; MutS homolog 6; MSI; microsatellite instability; pMMR; mismatch repair proficient; PMS2; postmeiotic segregation i
Importance of universal mismatch repair protein immunohistochemistry in patients with sebaceous neoplasia as an initial screening tool for Muir-Torre syndrome
Keywords: Sebaceous neoplasia; Muir-Torre syndrome; MLH1; MSH2; MSH6; PMS2
DNA mismatch repair enzymes: Genetic defects and autoimmunity
Keywords: AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun
DNA methylation analysis of cancer-related genes in oral epithelial cells of healthy smokers
Keywords: Epigenetic; DNA methylation; Smoking; MLH1; Telomerase; Oral cells;
Hypermethylation in gastric cancer
Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge
MLH1 and MSH2 mutation screening in HNPCC families of Hungary – Two new MMR gene mutations
Keywords: Hereditary Non-Polyposis Colorectal Cancer; Bethesda criteria; Modified Amsterdam criteria; MLH1; MSH2
Genes reparadores del ADN y pronóstico en formas esporádicas de carcinoma urotelial del tracto urinario superior
Keywords: PMS2; MLH1; Genes de reparación de ADN; Inestabilidad de microsatélites; Carcinoma urotelial; Tracto urinario superior; PronósticoPMS2; MLH1; DNA repair genes; Microsatellite instability; Urothelial carcinoma; Upper urinary tract; Prognosis
DNA repair genes and prognosis in sporadic forms of urothelial carcinoma of the upper urinary tract
Keywords: PMS2; MLH1; DNA repair genes; Microsatellite instability; Urothelial carcinoma; Upper urinary tract; PrognosisPMS2; MLH1; Genes de reparación de ADN; Inestabilidad de microsatélites; Carcinoma urotelial; Tracto urinario superior; Pronóstico
Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice
Keywords: p39cdk2/p-CDK2; SUN1; Meiosis; Telomere clustering; Synapsis; Recombination; Mouse; MLH1
Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung
Keywords: Adenocarcinoma; Squamous cell carcinoma; Lung; Hypermethylation; MLH1; MSH2Adenocarcinoma; Carcinoma das células escamosas; Pulmão; Hipermetilação; MLH1; MSH2
Conserved motifs of MutL proteins
Keywords: MutL; Multiple sequence alignment; MMR; DNA repair; MLH1; PMS2;
Lynch syndrome-associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach
Keywords: MSI; Colorectal carcinoma; Lynch syndrome; MLH1; BRAF; Screening;
Carcinoma colorrectal serrado. Descripción histopatológica, inmunohistoquÃmica y molecular de un caso
Keywords: BRAF; KRAS; MLH1; Inestabilidad de microsatélites; Neoplasia colorectal; BRAF; KRAS; MLH1; Microsatellite instability; Colorectal neoplasm;
Differential clinicopathologic features in microsatellite-unstable gastric cancers with and without MLH1 methylation
Keywords: Gastric cancer; Methylation; Microsatellite instability; MLH1
Histone modifications as a pathogenic mechanism of colorectal tumorigenesis
Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis
Keywords: Meiosis; Mlh1; Cullin4
Variant base excision repair proteins: Contributors to genomic instability
Keywords: BER; base excision repair; ROS; reactive oxygen species; SAM; S-adenosylmethionine; APE1; apurimidinic endonuclease I; MTH; MutT homolog; OGG1; DNA glycosylase 8-oxoguanine glycosylase; FapyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; 5-meC; 5-methylcy
DNA mismatch repair and the DNA damage response to ionizing radiation: Making sense of apparently conflicting data
Keywords: DNA mismatch repair; Ionizing radiation; Low dose; Hypersensitivity; MLH1; MSH2; RAD51; G2/M; Cell cycle arrest; Review
RAD51D protects against MLH1-dependent cytotoxic responses to O6-methylguanine
Keywords: Alkylating agents; Homologous recombination; Mismatch repair; MLH1; RAD51D;
Cancer genetics and reproduction
Keywords: hereditary cancer syndrome; ovarian cancer; endometrial cancer; BRCA1; BRCA2; MLH1; MSH2; hereditary non-polyposis colon cancer; lynch syndrome
Polymorphisms of MLH1 in benign prostatic hyperplasia and sporadic prostate cancer
Keywords: MLH1; Polymorphism; Prostate; Cancer
Expresión de MLH1, MSH2 y MSH6 en oncocitomas y carcinomas de células cromófobas renales
Keywords: Oncocitoma renal; carcinoma de células cromófobas; MLH1; MSH2; MSH6Renal oncocytoma; chromophobe cell renal cell carcinoma; MLH1; MSH2; MSH6
Human MutL-complexes monitor homologous recombination independently of mismatch repair
Keywords: ATM; ATR; BLM; DNA double-strand break repair; MLH1; MSH2