دانلود مقالات ISI درباره Mrp2 + ترجمه فارسی

Geniposidic acid protected against ANIT-induced hepatotoxity and acute intrahepatic cholestasis, due to Fxr-mediated regulation of Bsep and Mrp2

Keywords: GPA; Geniposidic acid; ANIT; α-naphthylisothiocyanate; Fxr; farnesoid X receptor; Bsep; bile salt export pump; Mrp2; multidrug resistance associated protein2; GOT; glutamic-Oxalacetic transaminase; GPT; glutamic pyruvic transaminase; γ-GT; γ-glutamyltr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo evaluation of anionic thiolated polymers as oral delivery systems for efflux pump inhibition

Keywords: MRP2; Alginate; Pectin; CMC; In vivo; Thiolated polymer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacokinetic synergy from the taxane extract of Taxus chinensis improves the bioavailability of paclitaxel

Keywords: Taxus chinensis var. mairei; Paclitaxel; Bioavailability; Pharmacokinetic synergy; Tissue distribution; Cytotoxicity; PTX; paclitaxel; P-gp; P-glycoprotein; CYP; cytochrome P450; MRP2; multidrug resistance protein 2; Cmax; peak plasma concentration; Tmax;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2

Keywords: AA; Aristolochic acid; AAI; Aristolochic acid I; AAN; Aristolochic acid nephropathy; BCRP; Breast cancer resistance protein; DMEM; Dulbecco's Modification of Eagle's Medium; FBS; Fetal bovine serum; HBSS; Hank's balanced salt solution; MRP2; Multidr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition

Keywords: Mrp2; Molecular mass; Inhibition; Permeation; Poly(acrylic acid)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Neochamaejasmin B increases the bioavailability of chamaechromone coexisting in Stellera chamaejasme L. via inhibition of MRP2 and BCRP

Keywords: Chamaechromone; Neochamaejasmin B; MRP2; BCRP; Bioavailability; Inhibition;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux

Keywords: Mrp2; multidrug resistance protein-2; Caco2; cancer of the colon cells; MDCKII; Madin-Darby canine kidney cells; ABC; ATP-binding cassette; Ap; apical; Bl; basolateral; HPLC; high pressure liquid chromatography; Q; quercetin; K; kaempferol; G; galangin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Modulation of the xenobiotic transformation system and inflammatory response by ochratoxin A exposure using a co-culture system of Caco-2 and HepG2 cells

Keywords: CYP450; NAT2; COX-2; LOX-5; MRP2; TEER measurement;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Intestinal absorption mechanisms of MTBH, a novel hesperetin derivative, in Caco-2 cells, and potential involvement of monocarboxylate transporter 1 and multidrug resistance protein 2

Keywords: MTBH; Flavonoids; MCT1; MRP2; Caco-2 cells; Passive diffusion

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro

Keywords: Res; resveratrol; Mdr1; multidrug resistance 1; Pept1; peptide transporter 1; Mrp2; multidrug resistance-associated protein 2; IGF-1R; insulin-like growth factor 1 receptor; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; ABC; ATP-bindi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance

Keywords: Intestine; MRP2; GST; cAMP; PKA; AP-1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

Keywords: ApG; adenine-guanine; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3 related kinase; Bax; Bcl2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; EdU; 5-ethynyl-2′-deoxyuridine; CarboPt; carboplatin; CENP-F; centromere protein F; Chk1; checkpoint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Simultaneous determination of lopinavir and three ester prodrugs by LC-MS/MS in lysates of BeWo cells

Keywords: BSA; bovine serum albumin; DLPV; diglycolic acid monoester of lopinavir; DPBS; Dulbecco's phosphate buffered saline; GLPV; glutaric acid monoester of lopinavir; LPV; lopinavir; MRP2; multidrug resistance-associated protein 2; Pgp; P-glycoprotein; RTV; rit

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

The Transport and Efflux of Glycosylated Luteinising Hormone-Releasing Hormone Analogues in Caco-2 Cell Model: Contributions of Glucose Transporters and Efflux Systems

Keywords: LHRH; SGLT1; GLUT2; transport; Caco-2 cell; peptides; MRP2; P-glycoprotein; glycosylation; efflux pumps;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity

Keywords: MRP2; multidrug resistance-associated protein 2; MDR1; multidrug resistance protein 1; BCRP; breast cancer resistance protein; EE; ethynylestradiol; GNT; genistein; ER; estrogen receptor; AP-1; activating protein-1; Sp1; specificity protein-1; PQ; paraqua

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The Combination of MK-5172, Peginterferon, and Ribavirin Is Effective in Treatment-Naive Patients With Hepatitis C Virus Genotype 1 Infection Without Cirrhosis

Keywords: Response-Guided Therapy; Sustained Virologic Response; Chronic HCV; Protease Inhibitor; ADME; absorption, distribution, metabolism, and excretion; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BOC; boceprevir; cEVR; complete early virolo

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2014 سفارش ترجمه

Potential role of ATP-binding cassette transporters in the intestinal transport of rhein

Keywords: ABC; ATP-binding cassettet; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP2; multidrug resistance-associated protein 2; B; basolateral; A; apical; MDCKII; Mardin-Darby canine kidney II; Rhein; ATP-binding cassette transporters; Rat in

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of rhinacanthin-C on function and expression of drug efflux transporters in Caco-2 cells

Keywords: Rhinacanthin-C; Naphthoquinone; P-glycoprotein; MRP2; Caco-2 cells;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of human biliverdin-IXα reductase by urea: Generation of kinetically distinct forms during the unfolding pathway

Keywords: hBVR-A; human biliverdin-IXα reductase; PQQ; pyrroloquinoline quinone; UGT1A1; bilirubin UDP-glucuronosyltransferase 1; Mrp2; multidrug resistance protein 2; HO-1; haem oxygenase 1; ROS; reactive oxygen species; QM/MM; quantum mechanics/molecular-mechani

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS)

Keywords: Excipients; MRP2; Caco-2; Membrane vesicles transport assay; SEDDS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Polycyclic aromatic hydrocarbons in food - Efflux of the conjugated biomarker 1-hydroxypyrene is mediated by Breast Cancer Resistance Protein (ABCG2) in human intestinal Caco-2 cells

Keywords: 1-OHP; 1-hydroxypyrene; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; BCRP; breast cancer resistance protein; B[k]F; benzo[k]fluoranthene; BP; benzo[a]pyrene; CYP; cytochrome P450 monooxygenase; INF; indeno[1,2,3-cd]fluoranthene; MRP2; multid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportPregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; BCRP; breast cancer related protein; BMDP; brain multidrug resistance protein; CNS; central nervous system; Fumitremorgin; C; hPXR; human PXR; Mrp2; multidrug resistance-associ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial

Keywords: BHNRC; Beltsville Human Nutrition Research Center; CYP1A2; cytochrome P450 family 1 subfamily A member 2; CYP2A6; cytochrome P450 family 2 subfamily A member 6; CV; control vegetables; GST; glutathione S-transferase; GSTA; glutathione S-transferase alpha;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2020 سفارش ترجمه

Carbon monoxide may enhance bile secretion by increasing glutathione excretion and Mrp2 expression in rats

Keywords: biliary secretion; carbon monoxide; glutathione; Mrp2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Constitutive androstane receptor upregulates Abcb1 and Abcg2 at the blood-brain barrier after CITCO activation

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BMDP; brain multidrug resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P450; pgCAR; porcine CAR; CITCO; 6-(4-c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of BSEP and MRP2 in mouse liver by miroestrol and deoxymiroestrol isolated from Pueraria candollei

Keywords: BSEP; bile salt export pump; EE2; 17α-ethenylestradiol; ES; estradiol benzoate; RT-PCR; reverse transcription-polymerase chain reaction; Miroestrol; Deoxymiroestrol; BSEP; MRP2; Bile salt export pump;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Impact of probe compound in MRP2 vesicular transport assays

Keywords: Drug transport; ABC transporter; Efflux; Membrane vesicle; MRP2; ABCC2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Keywords: BCRP, breast cancer resistance protein; MRP2, multidrug resistance-associated protein 2; Pgp, P-glycoproteinDrug transporters; Immunoquantification; BCRP; MRP2; P-glycoprotein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Transplantation/ImmunologyDecreased Mrp2 transport in severe macrovesicular fatty liver grafts

Keywords: Mrp2; Macrovesicular fatty liver; Liver transplantation; Marginal donor; PPARγ;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity

Keywords: ANIT; Gender; High-fat diet; Mrp2; Cholestasis; Hepatotoxicity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats

Keywords: JBP485; cyclo-trans-4-l-hydroxyprolyl-l-serine; ARF; acute renal failure; Oat; organic anion transporters; Mrp2; multidrug resistance-associated protein 2; BUN; blood urea nitrogen; IS; indoxyl sulfate; PAH; para-aminohippurate; MDA; malondialdehyde; SOD;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design

Keywords: Metabolic stability; Human liver microsomes; Human hepatocytes; Intrinsic clearance; Hepatic transporters; Drug discovery; ADME; Absorption, distribution, metabolism, and excretion; AO; Aldehyde oxidase; BCRP; Breast cancer resistance protein; CYP; Cytoch

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance‐associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy

Keywords: Gunn rats; EHBR rats; UGT1A; UGT2B; Hypothyroidism; Thyroxine; T4; Triiodothyronine; T3; Thyroid-stimulating hormone; TSH; Clobazam; Microsomal enzyme inducer; Efflux transporter; MRP2; Thyroid cellular hypertrophy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Rat Mrp2 gene expression is regulated by an interleukin-1β-stimulated biphasic response with enhanced transcription and subcellular shuttling of YB-1

Keywords: IL-1β; interleukin 1β; YB-1; Y-box protein-1; LPS; lipopolysaccharide; RT; reverse transcriptase; Mrp2; multidrug-resistance protein 2; MMP-2; matrix metalloproteinase 2; TNFα; tumor necrosis factor α; CFP; cyan fluorescent protein; YFP; yellow fluore

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds

Keywords: ABC; ATP-binding cassette; BDL; bile duct ligation; CAT; chloramphenicol acetyltransferase; CDDP; cisplatin; CGamF; cholylglycylamidofluorescein; FITC; fluorescein isothiocyanate; MRP; multidrug resistance-associated protein; MTX; mitoxantrone; NE; nuclea

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The effect of radixin knockdown on the expression and efflux function of MRP2 in SGC-7901 cells

Keywords: ERM; MRP2; Expression; Function; Regulation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Overexpression of multidrug resistance-associated protein 2 in the brain of pentylenetetrazole-kindled rats

Keywords: ABC; ATP-binding cassette; AED; antiepileptic drug; ANOVA; analysis of variance; BBB; blood-brain barrier; BSP; bromosulfophthalein; CT; control rats; ESI; electrospray ionization; i.p.; intraperitoneal; Mrp2; multidrug resistance-associated protein 2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Hiperbilirrubinemias y colestasis genéticas

Keywords: Colestasis; Ácidos biliares; Ácido ursodesoxicólico; ABCB4/MDR3; ABCB11/BSEP; FIC1/ ATP8B1; Colestasis gravídica; LPAC; Colestasis familiar; Bilirrubina; UGTA1; Enfermedad de Gilbert; Síndrome de Crigler-Najjar; Dubin-Johnson; MRP2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of cytochrome P450 gene expression in primary hepatocytes on various artificial extracellular matrices

Keywords: ASGPR; asialoglycoprotein receptor; BAL; bioartificial liver; BSA; bovine serum albumin; CYP; cytochrome P450; DAPI; 4′,6-diamidino-2-phenylindole; E-cad-Fc; E-cadherin-IgG Fc; ECM; extracellular matrix; EGF; epidermal growth factor; Mrp2; multidrug res

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Resveratrol inhibits genistein-induced multi-drug resistance protein 2 (MRP2) expression in HepG2 cells

Keywords: MRP2; Genistein; Resveratrol; Cancer chemopreventive phytochemical; RXRα;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of drug efflux transporters in poultry tissues

Keywords: Chicken; Efflux transporter; MDR1; MRP2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

The synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP using membranes obtained from Spodoptera frugiperda (Sf9)

Keywords: Sf9; Affinity chromatography; Drug discovery; Receptor screening; ABC transporters; P-glycoprotein; MRP1; MRP2; BCRP; Membrane receptors

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Biliary excretion in dogs: Evidence for a molecular weight threshold

Keywords: Biliary excretion; Dog; Molecular weight; ROC curve analysis; MRP2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles

Keywords: MRP2; ABCC2; Fluorescence assay; ABC protein; Carboxydichlorofluorescein (CDF)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional and post-transcriptional response of drug-metabolizing enzymes to PAHs contamination in red mullet (Mullus barbatus, Linnaeus, 1758): A field study

Keywords: Mullus barbatus; PAHs; CYP450; MRP2; GST; UDPGT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats

Keywords: Amiodarone; Mdr1; Mrp2; Cyp3a2; Mdr2; Rhodamine-123;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: Implications for lung cancer

Keywords: Lung cancer; Tobacco-specific carcinogen; NNK; MRP2; CFTR; Protein interaction

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Synergistic influence of Abcb1 and Abcc2 on disposition and sterol lowering effects of ezetimibe in rats

Keywords: ezetimibe; disposition; ABCB1; ABCC2; MRP2; P-gp; transporter; PSC833;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Transport of N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2)

Keywords: AA3; aminoacylase 3; DCVC; S-(1,2-dichlorovinyl)-l-cysteine; Ac-DCVC; N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine, Ac-DCVC; DDM; dodecyl β-d-maltopyranoside; E17bG; estradiol 17-β-d-glucuronide; HPLC; high performance liquid chromatography; GSH; reduced g

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Dose-Dependent Inhibition of Transporter-Mediated Hepatic Uptake and Biliary Excretion of Methotrexate by Cyclosporine A in an Isolated Perfused Rat Liver Model

Keywords: methotrexate; cyclosporine; drug interactions; isolated rat liver perfusion; hepatobiliary disposition; hepatic transport; hepatocyte uptake; biliary excretion; efflux pumps; Mrp2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه