Role of thrombophilic risk factors in children with non-stroke cerebral palsy
Keywords: Thrombophilia; Cerebral palsy; MTHFR; Factor V leiden; Factor II;
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Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients
Keywords: homocysteine; kidney transplantation; chronic allograft nephropathy; mortality; allograft loss; polymorphism; MTHFR; MTRR
An association between the methylenetetrahydrofolate reductase (MTHFR) C677T mutation and inflammation markers related to cardiovascular disease
Keywords: Inflammation; MTHFR; Cardiovascular; Risk factors;
Prenatal diagnosis for severe methylenetetrahydrofolate reductase deficiency by linkage analysis and enzymatic assay
Keywords: Prenatal diagnosis; Methylenetetrahydrofolate reductase; MTHFR; Linkage analysis; Homocystinuria; Homocysteine; Folate;
Homocysteine and schizophrenia: From prenatal to adult life
Keywords: CNS; central nervous system; HPLC; high performance liquid chromatography; ICD; International Classification of Diseases; KPMCP; Kaiser Permanente Medical Care Plan; MTHFR; methylenetetrahydrofolate reductase; NMDA; N-methyl-d-aspartate; NTD; neural tube
Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia
Keywords: MTHFR; methylenetetrahydrofolate reductase; NMDA; N-methyl-d-aspartic acid; tHcy; total plasma homocysteine concentration; Homocysteine; Methylenetetrahydrofolate reductase; Schizophrenia;
Aberrant folate status in schizophrenic patients: What is the evidence?
Keywords: MTHFR; methylenetetrahydrofolate reductase; Folate; Genetics; Homocysteine; Neurodevelopment; Psychiatric disorder; Schizophrenia; Vitamin;
Methylenetetrahydrofolate Reductase Gene Polymorphisms in Essential Hypertension
Keywords: Essential hypertension; hypertensive nephropathy; homocysteine; MTHFR; polymorphism;
Prevalence of Hyperhomocysteinemia in Adult Gluten-Sensitive Enteropathy at Diagnosis: Role of B12, Folate, and Genetics
Keywords: AGA; anti-gliadin antibodies; CI; confidence interval; DH; dermatitis herpetiformis; EMA; anti-endomysial antibodies; GFD; gluten-free diet; GSE; gluten-sensitive enteropathy; MTHFR; methylene-tetrahydrofolate reductase; RR; relative risk;
Basal cell carcinoma and variants in genes coding for immune response, DNA repair, folate and iron metabolism
Keywords: BCC; Cyclin D1; DNA repair gene; Interleukin gene; MTHFR; SNP;
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life
Keywords: MTHFR; Folate; B12; Homocysteine; Mental health; Aged; Genetics; Depression; Memory; Neuropsychology; Dementia; Alzheimer's disease; Elderly;
Prevalence of myocardial infarction is related to hyperhomocysteinemia but not influenced by C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms in diabetic and non-diabetic subjects
Keywords: DM; diabetes mellitus; Hcy; homocysteine; HDL-C; high-density lipoprotein; LDL-C; low-density lipoprotein; MI; myocardial infarction; MS; methionine synthase; MTHFR; methylenetetrahydrofolate reductase; Non-DM; non-diabetic; RBC; red blood cell; RF; risk
Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association
Keywords: MTRR; MTR; MTHFR; Folate; Homocysteine; Neural tube defects; Polymorphism; Spina bifida;
Schizophrenia and single-carbon metabolism
Keywords: CSF; cerebrospinal fluid; GSH; glutathione; MAT; methionine adenosyltrasferase; MTHFR; methylenetetrahydrofolate reductase; NAC; N-acetylcysteine; Homocysteine; Methionine; Schizophrenia;
Genetic Polymorphisms in Methylenetetrahydrofolate Reductase and Thymidylate Synthase and Risk of Pancreatic Cancer
Keywords: CI; confidence interval; MTHFR; methylenetetrahydrofolate reductase; OR; odds ratio; PCR-RFLP; polymerase chain reaction-based restriction fragment length polymorphism; TS; thymidylate synthase; UTR; untranslated region;
Pancreaticobiliary Cancers With Deficient Methylenetetrahydrofolate Reductase Genotypes
Keywords: CHLC; Cooperative Human Linkage Center; CI; confidence interval; COBRA; combined bisulfite restriction analysis; FAL; fractional allelic loss; LOH; loss of heterozygosity; MTHFR; methylenetetrahydrofolate reductase; OR; odds ratio; PCR; polymerase chain r
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer
Keywords: MTHFR; 5,10-methylenetetrahydrofolate reductase; CRC; colorectal cancer; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; ANOVA; analysis of variance; ors; odds ratios; CIs; confidence intervals; SD; standard deviation; Colo
Homocysteine and brain atrophy
Keywords: AD; Alzheimer's disease; Hcy; homocysteine; NMDA; N-methyl-d-aspartate; MPTP; neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MTHFR; methylenetetrahydrofolate reductase; PD; Parkinson disease; WMH; white matter hyperintensities; Alzheimer disease
Garlic extract attenuates hyperhomocysteinemia caused by folic acid deficiency in the rat
Keywords: AGE; aged garlic extract; EDTA; ethylenediaminetetraacetic acid; FA; folic acid; HPLC; high-performance liquid chromatography; MTHF; methyltetrahydrofolate; MTHFR; N5,N10-methylenetetrahydrofolate reductase; SAH; S-adenosylhomocysteine; SAM; S-adenosylmet
Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase
Keywords: MTHFR; Cerebellum; Apoptosis; Proliferation; Expression; Betaine;
Homocysteine and folate metabolism in depression
Keywords: BH4; tetrahydrobiopterin; BHMT; betaine-homocysteine methyltransferase; CBS; cystathionine-beta-synthetase; CNS; central nervous system; COMT; catechol methyl-transferease; DHFR; dihydrofolate reductase; HAM-D; Hamilton depression scale; Hcy; homocysteine
Cystathionine β Synthase Deficiency Promotes Oxidative Stress, Fibrosis, and Steatosis in Mice Liver
Keywords: α-SMA; α-smooth muscle actin; BHMT; betaine-homocysteine methyltransferase; CBS; cystathionine β synthase; CBS +/+ mice; wild-type mice; CBS +/â mice; heterozygous CBS-deficient mice; CBS â/â mice; homozygous CBS-deficient mice; DNPH; 2,4-dinitro
Idiopathic intracranial hypertension, polycystic-ovary syndrome, and thrombophilia
Keywords: ACLA; anticardiolipin antibody; APTT; activated partial thromboplastin time; BMI; body-mass index (kilograms per square meter); CSF; cerebrospinal fluid; DHEAS; dehydroepiandrosterone sulfate; DRVVT; dilute Russel's viper venom time; EDTA; ethylenediami
Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: Association is significant in men but not in women
Keywords: Bakirkoy; Erenkoy; Gender association; MTHFR; Polymorphism; Schizophrenia; Turkey;
High homocysteine serum levels in young male schizophrenia and bipolar patients and in an animal model
Keywords: BBB; blood-brain barrier; EDTA; ethylevediamine tetra-acetic acid; HPLC; high pressure liquid chromatography; MTHFR; methylenetetrahydrofolate reductase; MWM; Morris Water Maze; Bipolar disorder; Cerebrospinal fluid; Cognitive impairment; Folate; Functi
Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung
Keywords: AD; lung adenocarcinoma; APC; adenomatosis polyposis coli; CALCA; calcitonin-related polypeptide α; CDH1; E-cadherin; CDKN2A; cyclin-dependent kinase inhibitor 2A; ESR1; estrogen receptor 1; ESR2; estrogen receptor 2; GSTP1; glutathione S-transferase Ï;
The central nervous system in animal models of hyperhomocysteinemia
Keywords: ApoE; apolipoprotein E; CBS; cystathionie beta synthase; DOPAC; 3,4-dihydroxyphenylacetic acid; DZA; 3-deaza-adenosine; eNOS; endothelial nitric oxide synthase; GAD; glutamic acid decarboxylase; GLUT-1; glucose transporter type 1; HCA; homocysteic acid; 5
Perspectives on the molecular epidemiology of aerodigestive tract cancers
Keywords: ADH; alcohol dehydrogenase; APC; adenomatous polyposis coli; 5-AZA-CdR; 5-azacytidine2â²deoxycytidine; BPDE; benzo(a)pyrene diol epoxide; BRCA1; breast cancer1; CCND1; cyclin D1; CDH1; cadherin 1; CDH13; cadherin 13; CDK4; cyclin-dependent kinase 4; CDKN
Pharmacogenetics for individualized cancer chemotherapy
Keywords: Cancer drug resistance; Single nucleotide polymorphisms; Toxicity; ABC transporter; ATP-binding cassette transporter; BCRP; breast cancer-related protein; CDA; cytidine deaminase; CYP; cytochrome P450 monoxigenase; DPYD; dihydropyrimidine dehydrogenase; E
Folate and its preventive potential in colorectal carcinogenesis.
Keywords: Pte; pteroic acid; PteGlu; pteroylglutamic acid or folic acid; PteGlun; pteroylpolyglutamates or folates; H2PteGlun; 7,8-dihydrofolate; H4PteGlun; 5,6,7,8-tetrahydrofolates; 5-CH3-H4PteGlun; 5-methyl-tetrahydrofolate; 5-HCO-H4PteGlun; 5-formyl-tetrahydrof