دانلود مقالات ISI درباره Mtor + ترجمه فارسی

AMPK induced memory improvements in the diabetic population: A case study

Keywords: Type 2 diabetes (T2D); Alzheimer's disease (AD); Mild cognitive impairment (MCI); Ketogenic diet; High intensity interval training (HIIT); AMPK; mTOR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling

Keywords: Plk2; Polo-like kinase 2; TSC; tuberous sclerosis complex; mTOR; mammalian target of rapamycin; p70S6K/S6K; S6: Ribosomal protein S6 kinase; AMPK; AMP-responsive protein kinase; REDD 1; regulated in DNA damage and development 1; 4EBP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated osteoclastogenesis

Keywords: IL-21/IL-21R; AA-FLS; PI3K/Akt; mTOR; Nfatc1; Osteoclastogenesis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Sex-specific effects of CB1 receptor antagonism and stress in adolescence on anxiety, corticosterone concentrations, and contextual fear in adulthood in rats

Keywords: CB1; cannabinoid receptor type-1; PFC; prefrontal cortex; DH; dorsal hippocampus; PND; postnatal day; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; CORT; corticosterone; GAD67; glutamic acid decarboxyla

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in endometriosis: Friend or foe?

Keywords: Autophagy; Endometriosis; Friend; Foe; Mechanism; 3-MA; 3-methyladenine; ERK; extracellular signal-regulated kinase; MIS; Mullerian inhibiting substance; mTOR; Mammalian target of rapamycin; NF-κB; nuclear factor-k-gene binding κ; OH-1; heme oxygenase-1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Resistance to EGFR inhibitors in non-small cell lung cancer: Clinical management and future perspectives

Keywords: NNSCLC; non-small cell lung cancer; OS; overall survival; EGFR; epidermal growth factor receptor; TKI; tyrosine kinase inhibitor; ALK; Anaplastic lymphoma kinase; MET; mesenchymal epithelial transition factor; PFS; progression free survival; HER2; human e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function

Keywords: cardiac function; cell signaling; hypertrophy; metabolism; ATF4; activating transcription factor 4; BSO; L-buthionine-sulfoximine; GSH; reduced glutathione; LVEF; left ventricular ejection fraction; LVMi; left ventricular mass index; mTOR; mechanistic tar

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells

Keywords: AKT; protein kinase B (or PKB); ATC; anaplastic thyroid carcinoma; BRAF; v-Raf murine sarcoma viral oncogene homolog B (or B-RAF); EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase (or mitogen-activated protein kinase 1);

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

ALA-PDT suppressed the cell growth by Akt-/Erk-mTOR-p70 s6k pathway in human SZ95 sebocytes in vitro

Keywords: ALA; 5-aminolevulinicacid; PDT; photodynamictherapy; mTOR; mammalian targetof rapamycin; p70; S6 K p70S6Kinase p70S6; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; IGF; insulin-likegrowthfactor; AMPK; AMP-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages

Keywords: Macrophage; Podosome; Actin; PAK1; mTOR; mTORC2; RhoA; Rac-1; FTY720; Matrix degradation;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats

Keywords: LBP; Lycium barbarum polysaccharide; DM; diabetes mellitus; DPN; diabetic peripheral neuropathy; LC3-II; microtubule-associated protein 1 light chain 3-II; HDL; high density lipoprotein; SC; Schwarm cell; STZ; streptozotocin; LA; lipoic acid; PWT; paw wit

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass

Keywords: BAs; Bile acids; Cyp7a1; Cytochrome P450 family 7 subfamily A member 1; DCA; Deoxycholic acid; FXR; Farnesoid X receptor; GLP-1; Glucagon-like peptide-1; ip; Intraperitoneal; mTOR; mechanistic target of rapamycin; mTORC1; mechanistic target of rapamycin c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Reduced NGF in Gastric Endothelial Cells Is One of the Main Causes of Impaired Angiogenesis in Aging Gastric Mucosa

Keywords: Nerve Growth Factor; Angiogenesis; Endothelial Cells; Aging; Gene Therapy; Ulcer Healing; Akt; serine threonine kinase signaling protein; BrdU; bromodeoxyuridine; EC; endothelial cell; FITC; fluorescein isothiocyanate; GEC; gastric mucosal microvascular e

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds

Keywords: AMPK; adenosine monophosphate-activated protein kinase; APAB; 2,2′-azo-bisamidinopropane; BSA; bovine serum albumin; CCL4; carbon tetrachloride; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; DTPA; diethylenetriaminepentaacetic acid

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Correlation between telomerase and mTOR pathway in cancer stem cells

Keywords: CSCs; cancer stem cells; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AKT; serine/threonine kinase 1; hTERT; human telomerase reverse transcriptase; TERC; telomerase RNA component; GBM; glioblastoma multiforme; TRF1; telomeric rep

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance

Keywords: ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

The Current Status and Future Role of the Phosphoinositide 3 Kinase/AKT Signaling Pathway in Urothelial Cancer: An Old Pathway in the New Immunotherapy Era

Keywords: Bladder cancer; Inhibitors; mTOR; PI3K; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

The anti-osteosarcoma cell activity by a mTORC1/2 dual inhibitor RES-529

Keywords: Osteosarcoma; mTOR; RES-529; Akt and molecularly-targeted therapy;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism

Keywords: Ac; acetylated; ADA; the 3 AKT phosphorylation sites of FOXO1 are mutated; AKT; thymoma viral proto-oncogene; ATG; autophagy-related; AVOs; acidic vesicular organelles; AOI; antioxidant inhibitors; BECN1; beclin 1; BP; blank plasmid; CAT; catalase; CCK-8;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures

Keywords: HTT; Huntingtin; HD; Huntington's Disease; MID1; Midline 1; PP2A; Protein Phosphatase 2A; mHTT; Mutant Huntingtin; wtHTT; Wild type Huntingtin; S6K; 40S ribosomal S6 kinase; mTOR; Mammalian target of rapamycin; CGN; Cerebellar granule neurons; MAP2; Mic

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

The unknown face of IRE1α - Beyond ER stress

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring kinase enzyme 1; XBP1; x-box binding protein 1; bZIP; basic leucine zipper domain; HAC1; histone acetyl transferase 1; ATF; activating transcription factor; RIDD; regulate

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line

Keywords: Gentiana dinarica transformed roots; Xanthone; Norswertianin; Glioblastoma; Cell differentiation; Autophagy; GBM; Glioblastoma multiforme; Atg; autophagy-related proteins; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AMPK; AMP-act

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Binge-like ethanol treatment in adolescence impairs autophagy and hinders synaptic maturation: Role of TLR4

Keywords: TLR4; toll-like receptor 4; PFC; prefrontal cortex; PND; postnatal day; mTOR; mammalian target of rapamycin; LC3-II; light chain 3-II; PSD; postsynaptic density; SHANK3; SH3 and multiple ankyrin repeat domains 3; p62/SQSTM1; protein 62/sequestosome 1; ULK

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

T-Track-CMV and QuantiFERON-CMV assays for prediction of protection from CMV reactivation in kidney transplant recipients

Keywords: ATG; anti-thymocyte globulin; AUC; area under curve; CI; confidence interval; CMI; cell-mediated immunity; CMV; cytomegalovirus; CNI; calcineurin inhibitor; D; donor; GCV; Ganciclovir; HLA; human leukocyte antigens; KTx; kidney transplant; M; Month; MMF;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

The subsequent biological effects of simulated microgravity on endothelial cell growth in HUVECs

Keywords: Simulated microgravity; Growth inhibition; miR-22; Serum response factor; LAMC1; mTOR;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR

Keywords: Lipopolysaccharide; Acute lung injury; Metformin; AMPK; mTOR;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways

Keywords: Cardiac glycoside; Anti-Cancer; Helleborus thibetanus Franch.; Apoptosis; ERK and JNK pathways; PI3K-Akt-mTOR pathway; CGs; cardiac glycosides; FEN1; flap endonuclease 1; PARP; (poly (ADP-ribose) polymerase; MAPK; mitogen-activated protein kinase; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology

Keywords: AMPK; 5′AMP-activated protein kinase; LRRK2; Leucine rich repeat kinase; LAMP1; Lysosomal associated membrane protein 1; iPD; idiopathic PD; mTOR; mammalian target of rapamycin; LC3; microtubule-associated protein1A/1B light chain 3; PD; Parkinson's d

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization

Keywords: Vaccine; Bet v 1; flagellin; rFlaA; fusion protein; birch pollen allergy; IL-10 dendritic cell; mammalian target of rapamycin; metabolism; alum; Aluminum hydroxide; APC; Antigen-presenting cell; B/A; Bet v 1/alum; DC; Dendritic cell; 2-DO; 2-Deoxyglucose;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of mTOR complexes protects cancer cells from glutamine starvation induced cell death by restoring Akt stability

Keywords: Akt; Autophagy; Cancer metabolism; Cell survival; Glutamine; mTOR;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

PKM2, a potential target for regulating cancer

Keywords: PK; pyruvate kinase; HCC; hepatocellular carcinoma; FBP; fructose 1,6-bisphosphate; SAICAR; Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-50-phosphate; hnRNPs; heterogeneous nuclear ribonucleoproteins; PTB; polypyrimidine tract-binding protein; NEK2; n

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Promising horizon to alleviate Alzeheimer's disease pathological hallmarks via inhibiting mTOR signaling pathway: A new application for a commonplace analgesic

Keywords: Alzheimer's disease; Autophagy; mTOR; Tau phosphorylation; Tramadol;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

High collagen density augments mTOR-dependent cancer stem cells in ERα+ mammary carcinomas, and increases mTOR-independent lung metastases

Keywords: Breast cancer; Luminal B subtype; Extracellular matrix density/ stiffness; Cancer stem cells; mTOR;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo

Keywords: NB; Neuroblastoma; IGF; Insulin and insulin-like growth factors; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; p70S6K; p70 ribosomal protein S6 kinase; 4E-BP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

Keywords: DEPDC5; Focal cortical dysplasia; mTOR; Familial focal epilepsy; Seizures; Conditional knockout; Megalencephaly;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling

Keywords: Insulin resistance; FTO; TSC1; mTOR; Tau; AD; Diabetes;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

BCA3 contributes to the malignant progression of hepatocellular carcinoma through AKT activation and NF-κB translocation

Keywords: Hepatocellular carcinoma; Breast cancer-associated protein 3; AKT; MTOR; NF-κB;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Hydromorphone protects CA1 neurons by activating mTOR pathway

Keywords: Hydromorphone (HM); Ischemia-reperfusion (IR) injury; mTOR; Oxidative stress; Bcl-2;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies

Keywords: Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy

Keywords: Nitrite; mTOR; Oxidative stress; Cardiac remodeling; Hypertension;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Copine1 regulates neural stem cell functions during brain development

Keywords: Copine1; Neural stem cell; Neurogenesis; Gliogenesis; mTOR; CPNE1; Copine 1; NSC; Neural stem cell; ES cell; Embryonic stem cell;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Gut microbiota and mTOR signaling: Insight on a new pathophysiological interaction

Keywords: Gut microbiota; mTOR; Butyrate; Obesity; Diabetes; Colon cancer;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease

Keywords: Asthma; house dust mite; glycolysis; IL-1; inhibitor of κB kinase ε; lactate; lactate dehydrogenase A; AHR; Airways hyperresponsiveness; BAL; Bronchoalveolar lavage; BMI; Body mass index; DC; Dendritic cell; 2-DG; 2-Deoxyglucose; ECAR; Extracellular aci

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway

Keywords: JPJD; Jianpi Jiedu decoction; CRC; colorectal cancer; TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labeling; IHC; immunohistochemistry; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; mTOR; mammalian target of rapamyc

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Liver Angiomyolipomas in Tuberous Sclerosis Complex-Their Incidence and Course

Keywords: tuberous sclerosis; mTOR; angiomyolipoma; mTOR inhibitors; everolimus; TSC1; TSC2;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluation of miRNAs expression in medullary thyroid carcinoma tissue samples: miR-34a and miR-144 as promising overexpressed markers in MTC

Keywords: MTC; AXL; mTOR; miR-144; miR-34a;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

High glucose up-regulates Semaphorin 3A expression via the mTOR signaling pathway in keratinocytes: A potential mechanism and therapeutic target for diabetic small fiber neuropathy

Keywords: Semaphorin 3A; Diabetic small fiber neuropathy; Keratinocyte; mTOR; 4E-BP1; Eukaryotic initiation factor 4E-binding protein 1; AD; atopic dermatitis; CPT; cold perception threshold; DPN; diabetic peripheral neuropathy; DRG; dorsal nerve root ganglia; FPG;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway

Keywords: ɑ-Tocopherol; Depression; Autophagy; mTOR; AMPK; Behaviour;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Dysregulation of mRNA translation and energy metabolism in cancer

Keywords: mRNA translation; Energy metabolism; mTOR; Cancer;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه