دانلود مقالات ISI درباره Mtor + ترجمه فارسی

p70 S6-kinase mediates the cooperation between Akt1 and Mek1 pathways in fibroblast-mediated extracellular matrix remodeling

Keywords: Akt1; Mek1; mTOR; p70 S6-kinase; Extracellular matrix; Integrin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells

Keywords: DDIT4; Baicalein; mTOR; IRF1; Cellular stress;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleSIRT1 regulates oncogenesis via a mutant p53-dependent pathway in hepatocellular carcinoma

Keywords: HCC; hepatocellular carcinoma; RFS; relapse-free survival; OS; overall survival; mTOR; mammalian target of rapamycin; SIRT1; silent mating-type information regulation 2 homolog 1; AMPK; AMP-activated protein kinase; ROS; reactive oxygen species; ACC; acet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Radiosensitization of metformin in pancreatic cancer cells via abrogating the G2 checkpoint and inhibiting DNA damage repair

Keywords: Metformin; Radiosensitizer; Pancreatic cancer; Wee1; Rad51; mTOR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells

Keywords: Autoimmunity; Drug delivery; Immunomodulation; Nanoparticles; TGF-β; Interleukin-2; CD; cluster of differentiation; DMSO; dimethylsulfoxide; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescent activated cell sorting; FBS; fetal bovine serum; GFP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine

Keywords: Cocaine; mTOR; Cell signaling; Nucleus accumbens; Dopamine; Raptor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of mTOR dependent signaling pathway is a necessary mechanism of antidepressant-like activity of zinc

Keywords: Zinc; FST; mTOR; PKA; PKC; PI3K; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Akt, PKB; protein kinase B; BDNF; brain derived neurotrophic factor; CaMKII; Ca2+-and calmodulin-dependent protein kinase II; CNS; central nervous system; eEF2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Metabolic control of regulatory T cell development and function

Keywords: metabolism; vitamin; commensal microbiota; SCFA; mTOR; obesity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Erratum to ARID2, p110α, p53, and β-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications

Keywords: Immunohistochemistry; Hepatocarcinogenesis; mTOR; Oncoprotein; Recurrence

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

AT-rich interactive domain 2, p110α, p53, and β-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications

Keywords: Immunohistochemistry; Hepatocarcinogenesis; mTOR; Oncoprotein; Recurrence

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Fibronectin promotes cell proliferation and invasion through mTOR signaling pathway activation in gallbladder cancer

Keywords: Fibronectin; Gallbladder cancer; mTOR; Proliferation; Invasion;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth

Keywords: mTOR; Glut3; NFκB; Aerobic glycolysis; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

mTOR and its tight regulation for iNKT cell development and effector function

Keywords: iNKT cell; mTOR; Raptor; Rictor; TSC1/2; Diacylglycerol kinases; RasGRP1; PTEN; Ras; CARMA1; iNKT1; iNKT2; iNKT17; Signal transduction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of mTOR pathway restrains astrocyte proliferation, migration and production of inflammatory mediators after oxygen-glucose deprivation and reoxygenation

Keywords: Mammalian target of rapamycin; Reactive astrogliosis; Oxygen-glucose deprivation; Proliferation; Migration; Inflammation mediator; EdU; 5-ethynyl-29-deoxyuridine; mTOR; mammalian target of rapamycin; p-mTOR; phosphorylated mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activated AMPK boosts the Nrf2/HO-1 signaling axis-A role for the unfolded protein response

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated kinase; ARE; antioxidant response element; βTrcP1; β-transducin-repeat containing protein 1; CaMKK; calcium calmodulin-dependent kinase kinase; CHO; Chinese hamster ovary; DCF; dichlorofluorescein; DMSO;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade

Keywords: IR; insulin receptor; IGFR; insulin-like growth factor receptor; IRS-1; insulin receptor substrate-1; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of rapamycin; Grb2; growth factor receptor-bound protein 2; FGF2; fibroblast growth factor 2; DTP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression

Keywords: MicroRNA; Diabetic nephropathy; mTOR; Mesangial cell pathology;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

PI3K/Akt signaling in osteosarcoma

Keywords: OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: A tale of two complexes

Keywords: mTOR; mTORC1; mTORC2; S6K; 4E-BP1; GBM;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway

Keywords: 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2′-deoxyguanosine; AMPK; 5′ AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The proliferation of amplifying neural progenitor cells is impaired in the aging brain and restored by the mTOR pathway activation

Keywords: Aging; Stem cell; Proliferation; Neurogenesis; mTOR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Do airborne biogenic chemicals interact with the PI3K/Akt/mTOR cell signalling pathway to benefit human health and wellbeing in rural and coastal environments?

Keywords: Autophagy; Cell-signalling; Green-blue space; mTOR; Phytochemicals;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Fatty acid metabolism in the regulation of T cell function

Keywords: T cells; fatty acids; fatty acid oxidation; fatty acid synthesis; mTOR; ACC; AMPK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Original StudyA Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer

Keywords: mTOR; PI3K; Positron emission tomography; Prostatic adenocarcinoma; PTEN;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy and proteins involved in vesicular trafficking

Keywords: AMD; age-related macular degeneration of the eye; AMPK; AMP-activated protein kinase; ATG; autophagy-related protein; CMA; chaperone-mediated autophagy; COPII; coat protein complex II; DFCP1; double FYVE domain-containing protein 1; EGF; epidermal growth

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of AMPK accentuates prolonged caloric restriction-induced change in cardiac contractile function through disruption of compensatory autophagy

Keywords: Caloric restriction; AMPK; Myocardial; Autophagy; mTOR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice

Keywords: ASD; autism spectrum disorders; TSC; tuberous sclerosis complex; mTOR; mechanistic target of rapamycin; PTEN; phosphatase and tensin homolog; 5-HT; 5-hydroxytryptophan; SerT/Slc6a4; serotonin transporter; CaMKIIα; Ca2 +/calmodulin-dependent protein kina

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

mTOR signaling controls VGLUT2 expression to maintain pain hypersensitivity after tissue injury

Keywords: ANOVA; one-way analysis of variance; CGRP; anti-calcitonin gene-related peptide; DRG; dorsal root ganglion; IB4; biotin-conjugated isolectin B4; mTOR; mammalian target of rapamycin; p-mTOR; phosphorylated mTOR; TRPV1; transient receptor potential vanilloi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in diabetic nephropathy

Keywords: mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; DN; diabetic nephropathy; EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; GBM; glomerular basement membrane; STZ; streptozotocin; Diabetic nephropathy; Epithelial-mesenchy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Control of macrophage metabolism and activation by mTOR and Akt signaling

Keywords: mTOR; Akt; Macrophage activation; Macrophage metabolism; Immunometabolism

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The PI3K/AKT Pathway and Renal Cell Carcinoma

Keywords: PI3K; AKT; mTOR; Renal cell carcinoma; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy

Keywords: mTOR; Alzheimer disease; Autophagy; Down Syndrome

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

Keywords: mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload

Keywords: Cardiac hypertrophy; Fibrosis; PHF8; mTOR; Rapamycin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Xanthohumol from Humulus lupulus L. induces glioma cell autophagy via inhibiting Akt/mTOR/S6K pathway

Keywords: Autophagy; Glioblastoma multiforme; MAPK; mTOR; Xanthohumol;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of the PI3K/AKT Pathway and Fuel Utilization During Primate Torpor in the Gray Mouse Lemur, Microcebus murinus

Keywords: Insulin signaling pathway; PI3K/AKT; mTOR; GSK3; Pyruvate dehydrogenase; Metabolic rate depression

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

Keywords: Actb; β-actin; AMPK; adenosine monophosphate protein kinase; Bgn; biglycan; CDK; cyclin-dependent kinase; Dcn; decorin; EGFR; epidermal growth factor receptor; GFP; green fluorescent protein; IGF-IR; insulin-like growth factor receptor I; LC3; microtubul

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Esclerosis tuberosa de Bourneville

Keywords: Esclerosis tuberosa de Bourneville; Genodermatosis; Hamartoma; Angiofibromas; Astrocitomas de células gigantes; mTOR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Incidence and risk of xerosis with targeted anticancer therapies

Keywords: Bcr-Abl; CD20; CD52; dry skin; EGFR; HDAC; HER2; incidence; MEK; mTOR; Raf; risk; xerosis; VEGFRADL, activities of daily living; AE, adverse event; CI, confidence interval; CTCAE, Common Terminology Criteria for Adverse Events; dAE, dermatologic adverse e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Rapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea

Keywords: Transplantation; Sodium Transport; mTOR; ImmunosuppressionAMC, Albany Medical College; mTOR, mammalian target of rapamycin; NHE3, Na+/H+ exchanger 3

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Keywords: Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive companion of mTOR; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; m-TORC2; mTOR complex 2; Sp1; specific protein 1; MTH; mithramycin; RAPA; rapamycin; ChIP; chromat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival

Keywords: Photoreceptors; Cone survival; PI3K; mTOR; Diabetic retinopathy; Retinitis pigmentosa; Visual function; Neuroprotective;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Cohesin modulates transcription of estrogen-responsive genes

Keywords: ER; estrogen receptor alpha; ERE; estrogen response element; TAD; topologically associated domain; CdLS; Cornelia de Lange Syndrome; FOXA1; Forkhead Box A1; GATA3; GATA Binding Protein 3; ChIP; chromatin immunoprecipitation; ErbB; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT3 protects cells from hypoxia via PGC-1α- and MnSOD-dependent pathways

Keywords: Δψ; mitochondrial membrane potential; DMSO; dimethyl sulfoxide; HBSS; Hanks' balanced salt solution; LDH; lactate dehydrogenase; MnSOD; manganese superoxide dismutase; MOI; multiplicity of infection; mTOR; mammalian target of rapamycin; MTT; 3-(4,5-di

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of tubular Flcn expression as a mouse model for renal tumor induction

Keywords: BHD; FLCN; gene targeting; kidney cancer; mouse model; mTOR; RCC; TGF-β;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin

Keywords: AKAP; A-kinase anchoring proteins; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; BSA; bovine serum albumin; C and R; catalytic and regulatory regions; cAMP; adenosine 3′,5′-cyclic monophosphate; Cav-1; caveolin-1; CREB; cAMP response element bindin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Similar PDK1–AKT–mTOR pathway activation in balloon cells and dysmorphic neurons of type II focal cortical dysplasia with refractory epilepsy

Keywords: Focal cortical dysplasia; Intractable epilepsy; mTOR; Balloon cells; Dysmorphic neurons

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Mammalian target of rapamycin complex 1 (mTORC1) Is required for mouse spermatogonial differentiation in vivo

Keywords: Translation; Spermatogonia; Retinoic acid; Testis; Spermatogenesis; mTOR

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه