دانلود مقالات ISI درباره Mtor + ترجمه فارسی

Phenotypes associated with inherited and developmental somatic mutations in genes encoding mTOR pathway components

Keywords: mTOR; Mamalian target of rapamycin; PI3K; phosphoinositide 3-kinase related kinase; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; AMP; Adenosine monophosphate; ATP; Adenosine triphosphate; S6K; ribosomal S6 Kinase; 4E-BP1; eukaryotic initiation factor 4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Efficacy of everolimus in second- and third-line therapy for metastatic renal cell carcinoma: A registry-based analysis1

Keywords: Everolimus; mTOR; Renal cell carcinoma; Tyrosine kinase inhibitors; Therapy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR inhibitors and their clinical application in cervical, endometrial and ovarian cancers: A critical review

Keywords: mTOR; Gynecologic cancer; Cervical; Endometrial; Ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome virus (PRRSV) replication

Keywords: PRRSV; mTOR; Akt; Autophagy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DNA topoisomerases in mtDNA maintenance and ageing

Keywords: AMPK; AMP-dependent protein kinase; AMPKα2; alpha-subunit of AMP-dependent protein kinase; MEFs; Murine embryonic fibroblasts; mtDNA; mitochondrial DNA; mTOR; Mammalian target of rapamycin; ROS; Reactive oxygen species; TFAM; Mitochondrial transcription

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR inhibition: A promising strategy for stabilization of atherosclerotic plaques

Keywords: Atherosclerosis; mTOR; Rapamycin; Everolimus; Drug-eluting stent; Autophagy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Human cytomegalovirus latent infection alters the expression of cellular and viral microRNA

Keywords: miRNAs; microRNAs; HCMV; human cytomegalovirus; THP-1; human monocytic leukemia cell line; nt; nucleotides; mRNAs; messenger RNAs; 3′ UTR; 3′ untranslated regions; AIDS; Acquired Immune Deficiency Syndrome; HSV-1; herpes simplex virus 1; LATs; latency

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy is induced by raptor degradation via the ubiquitin/proteasome system in granular corneal dystrophy type 2

Keywords: Autophagy; Granular corneal dystrophy type 2; mTOR; Raptor; TGFBIp; Ubiquitin/proteasome system;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

β-Hydroxy-β-methylbutyrate facilitates PI3K/Akt-dependent mammalian target of rapamycin and FoxO1/3a phosphorylations and alleviates tumor necrosis factor α/interferon γ-induced MuRF-1 expression in C2C12 cells

Keywords: FoxO; forkhead box class O; HMB; β-Hydroxy-β-methylbutyrate; IFN-γ; interferon γ; mTOR; mammalian target of rapamycin; MuRF-1; muscle RING-finger protein-1; PI3K; phosphatidylinositol 3-kinase; TNF-α; tumor necrosis factor-α; β-Hydroxy-β-methylbut

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Next-generation sequencing of salivary high-grade neuroendocrine carcinomas identifies alterations in RB1 and the mTOR pathway

Keywords: NEC; neuroendocrine carcinoma; MCPyV; Merkel cell polyomavirus; FFPE; formalin-fixed paraffin-embedded; Salivary; Neuroendocrine carcinoma; Retinoblastoma 1 (RB1); mTOR; Targeted next generation sequencing;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Helicobacter pylori promotes eukaryotic protein translation by activating phosphatidylinositol 3 kinase/mTOR

Keywords: H. pylori; mTOR; S6 ribosomal protein; eIF4; Protein synthesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dihydromyricetin induces autophagy in HepG2 cells involved in inhibition of mTOR and regulating its upstream pathways

Keywords: DHM; dihydromyricetin; mTOR; mammalian targets of rapamycin; ERK1/2; extracellular signal-regulated kinase 1/2; AMPK; AMP-activated kinase; PI3K; class III phosphatidylinositol 3-kinase; PDK 1; phosphoinositide-dependent protein kinase 1; Akt; protein kin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The anti-inflammatory effect of 3-deoxysappanchalcone is mediated by inducing heme oxygenase-1 via activating the AKT/mTOR pathway in murine macrophages

Keywords: 3-Deoxysappanchalcone; Heme oxygenase-1; Anti-inflammatory effect; Translation; mTOR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Transient increase in proteinuria, poly-ubiquitylated proteins and ER stress markers in podocyte-specific autophagy-deficient mice following unilateral nephrectomy

Keywords: UNX; unilateral nephrectomy/uninephrectomy; GFP; green fluorescent protein; mTor; mammalian target of rapamycin; Autophagy; Atg7; Podocyte; Nephrectomy; Ubiquitin; ER stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR Signaling in Autophagy Regulation in the Kidney

Keywords: Autophagy; rapamycin; mTOR; mTORC1; AMPK; renal proximal tubular cell; podocyte;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR-dependent transcriptional repression of Pdcd4 tumor suppressor in lung cancer cells

Keywords: Pdcd4; Tumor suppressor; mTOR; Transcriptional suppression; Lung cancer cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The human myometrium differentially expresses mTOR signalling components before and during pregnancy: Evidence for regulation by progesterone

Keywords: mTOR; Myometrium; Progesterone; Preterm labour

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting bone metastatic cancer: Role of the mTOR pathway

Keywords: Bone metastatic cancer; mTOR; Everolimus; Cellular signaling; Osteoclast; Osteoblast;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; caRags; constitutively active Rags B and C; caRheb; constitutively active Rheb; caRhoA; constitutively active RhoA; mTOR; mechanistic target of rapamycin; mTORC; mechanistic target of rapamycin co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling

Keywords: ANOVA; analysis of variance; CUL7; Cullin7; CRL7; Cullin RING E3 ubiquitin ligase 7; FBXW8; F-box/WD repeat-containing protein 8; GLUT4; glucose transporter 4; HSP90; heat shock protein 90; IRS; insulin receptor substrate; IGF-1; insulin-like growth hormo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dysregulation of the IGF-I/PI3K/AKT/mTOR signaling pathway in autism spectrum disorders

Keywords: AKT; mTOR; Autism spectrum disorders; Rett syndrome

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Rapamycin Treatment of Healthy Pigs Subjected to Acute Myocardial Ischemia-Reperfusion Injury Attenuates Cardiac Functions and Increases Myocardial Necrosis

Keywords: AAR; Area at risk; ADP; adenosine diphosphate; AKT; Protein kinase B; ANOVA; Analysis of variance; cTnI; Cardiac troponin I; dP/dT Max; left ventricular maximum contractility; dV/dT max; Left ventricular maximum filling; ECL; Enhanced chemiluminescense; E

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Blockage of Stat3 enhances the sensitivity of NSCLC cells to PI3K/mTOR inhibition

Keywords: Akt; Bim; CHOP; mTOR; PI3K; Stat3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014

Keywords: 3-MA; 3-methyaldenine; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; mTOR; mammalian target or rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; S6K; p70-S6 Kinase 1; LC3B; light chain 3B; Colorectal cancer; AZD-2014; mTOR complexes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Rapamycin-mediated CD36 translational suppression contributes to alleviation of hepatic steatosis

Keywords: Rapamycin; CD36; Translation; mTOR; NAFLD;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

Keywords: Acsl; long-chain acyl-CoA synthetase; FA; fatty acid; mTOR; mechanistic target of rapamycin; mTORC1; mTOR complex-1; MPI; mean performance index; Fatty acid oxidation; mTOR; Insulin resistance; Gene expression; Ventricular function; Substrate switching;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors

Keywords: UPR; Calpains; Mitochondria; mTOR; Autophagy; Rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways

Keywords: EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; mTOR; mammalian target of rapamycin; mTORC2; mTOR complex 2; RMAECs; rat mesenteric arterial endothelial cells; rTERT; rat telomerase reverse transcriptase; SA-β-gal; senescence-as

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

GABARBP down-regulates HIF-1α expression through the VEGFR-2 and PI3K/mTOR/4E-BP1 pathways

Keywords: GABARBP; human γ-aminobutyrate type A (GABAA) receptor-binding protein; VEGF; vascular endothelial growth factor; HIF-1α; hypoxia-inducible factor-1α; PDK1; phosphoinositide-dependent protein kinase-1; mTOR; mammalian target of rapamycin; TSC-2; tubero

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTORC1 signaling controls multiple steps in ribosome biogenesis

Keywords: 4E-BP; eIF4E-binding protein; 5′-TOP; 5′-terminal oligopyrimidine tract; BOP1; block of proliferation 1; eEF2; eukaryotic elongation factor; eEF2K; eEF2 kinase; eIF; eukaryotic initiation factor; ERK; extracellular ligand-regulated kinase; MEK; MAP an

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Biological significance of 18F-FDG uptake on PET in patients with non-small-cell lung cancer

Keywords: 18F-FDG PET; NSCLC; GLUT1; Hypoxia; mTOR; PTEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells

Keywords: Amino acids; Anabolic signaling; C2C12; Skeletal muscle; mTOR; Protein synthesis; ANOVA; analysis of variance; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; FBS; fetal bovine serum; mTOR; mechanistic target of rapamycin; mTORC1; mechanistic t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A phase Ib study investigating the combination of everolimus and dovitinib in vascular endothelial growth factor refractory clear cell renal cancer

Keywords: Dovitinib; Everolimus; Combination; Renal cancer; FGF; VEFG; mTOR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Ginsenoside Rg1 regulates innate immune responses in macrophages through differentially modulating the NF-κB and PI3K/Akt/mTOR pathways

Keywords: Ginsenoside Rg1; Tumor necrosis factor-α; Interleukin-6; mTOR; Macrophages; Lipopolysaccharide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR inhibition of cardamonin on antiproliferation of A549 cells is involved in a FKBP12 independent fashion

Keywords: cardamonin (PubChem CID: 641785)Cardamonin; mTOR; Rapamycin; Proliferation; Apoptosis; FKBP12

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy in regulation of acute lung injury: a review and perspective

Keywords: mTOR; Autophagy; Acute lung injury

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Status of PI3K/Akt/mTOR Pathway Inhibitors in Lymphoma

Keywords: Akt; Lymphoma; mTor; PI3K; Review; Signalling; Targeted; Therapy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Leptin modulates autophagy in human CD4+CD25− conventional T cells

Keywords: mTOR; mammalian-target of rapamycin; TCR; T cell receptor; hLepRb; human leptin receptor-b; LC3-II; microtubule associated protein light chain 3-II; Tconv; T conventional; Leptin; Autophagy; T cells; Metabolism; mTOR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleDevelopment and validation of a polycystic liver disease complaint-specific assessment (POLCA)

Keywords: PCLD; polycystic liver disease; SA; somatostatin analogue; LTx; liver transplantation; POLCA; PCLD complaint-specific assessment; SF36; 36-item short form health survey; CT; computed tomography; LV; liver volume; LAN; lanreotide; mTOR; mammalian target of

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular and cellular pharmacologyThe dual PI3K/mTOR inhibitor NVP-BEZ235 prevents epithelial-mesenchymal transition induced by hypoxia and TGF-β1

Keywords: EMT; Epithelial-mesenchymal transition; Hif; hypoxia inducible factor; HRE; Hif-responsive elements; ILK; Integrin-linked kinase; mTOR; Mammalian Target of Rapamycin; PI3K; Phosphatidyl Inositol 3-kinase; RTV; relative tumor volume; TGF; Transforming gr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Protective effect of 7-O-succinyl macrolactin A against intestinal inflammation is mediated through PI3-kinase/Akt/mTOR and NF-κB signaling pathways

Keywords: 5-ASA; 5-aminosalycilic acid; BCECF-AM; 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein-acetoxymethyl ester; CD; Crohn's disease; DMSO; dimethyl sulfoxide; ELISA; enzyme linked immunosorbent assay; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-ph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking

Keywords: ABC; ATP-binding cassette; Akt; v-Akt murine thymoma viral oncogene homolog 1; BCRP; breast cancer resistance protein; EGFR; epidermal growth factor; MAPK; mitogen-activated protein kinase; MDR; multidrug resistance; mTOR; mammalian target of rapamycin; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Exémestane-évérolimus dans les cancers du sein métastatiques de la femme ménopausée, HER2-négatifs, exprimant les récepteurs hormonaux et résistants aux inhibiteurs de l'aromatase non stéroïdiens : une nouvelle option thérapeutique

Keywords: exémestane; évérolimus; cancer du sein métastatique; mTOR; hormonorésistance; exemestane; everolimus; metastatic; breast cancer; mTOR; hormonoresistance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Subchronic toxicity study of β-hydroxy-β-methylbutyric free acid in Sprague-Dawley rats

Keywords: A/G ratio; albumin to globulin ratio; ALT; alanine aminotransferase; ANOVA; analysis of variance; AST; aspartate aminotransferase; CaHMB; calcium β-hydroxy-β-methylbutyrate-monohydrate; FDA; Food and Drug Administration; GGT; gamma-glutamyltransferase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

miRNA expression analysis in cortical dysplasia: Regulation of mTOR and LIS1 pathway

Keywords: Cortical dysplasia; miRNA; Microarray; mTOR; LIS1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α

Keywords: Cucurbitacin B; HIF-1α; Translation; mTOR; Antitumor activity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Iron chelators induce autophagic cell death in multiple myeloma cells

Keywords: Iron chelation; Deferasirox; Deferoxamine; Multiple myeloma; Autophagy; mTOR; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Tetracyclines cause cell stress-dependent ATF4 activation and mTOR inhibition

Keywords: Doxycycline; Minocycline; mTOR; ATF4; Endoplasmic reticulum stress; Magnesium

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Minocycline inhibits angiogenesis in vitro through the translational suppression of HIF-1α

Keywords: HIF-1; VEGF; Minocycline; mTOR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه