
Mitochondrial tRNA cleavage by tRNA-targeting ribonuclease causes mitochondrial dysfunction observed in mitochondrial disease
Keywords: mnm5U; 5-methylaminomethyluridine; MELAS; mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes; MERRF; myoclonic epilepsy with ragged-red fibers; MTS; mitochondrial-targeting sequence; TALEN; transcription activator-like effector