دانلود مقالات ISI درباره Nfts + ترجمه فارسی

آلفای گیرنده مرتبط با استروژن در آسیب شناسی بیماری آلزایمر دخیل است

Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology

Keywords: Estrogen-related receptor α; APP/PS1 mice; Amyloidogenesis; Tau phosphorylation; Aβ; amyloid protein; AD; Alzheimer's disease; ADAM10; a disintegrin and metalloproteinase 10; AMPK; AMP-activated protein kinase; APP; β-amyloid precursor protein; APP/PS1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

دارچین، چشم انداز امیدوار کننده به بیماری آلزایمر

Cinnamon, a promising prospect towards Alzheimer's disease

Keywords: AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

قرار گرفتن در معرض گلوتامات مونونوسیدیم در طی دوره نوزادان منجر به نقص شناختی در موش صحرایی اسپراگ داولی

Monosodium glutamate exposure during the neonatal period leads to cognitive deficits in adult Sprague-Dawley rats

Keywords: AD; Alzheimer's disease; T2DM; Type 2 diabetes mellitus; SD rats; Sprague-Dawley rats; MSG; monosodium glutamate; CNS; central nervous system; Aβ; beta-amyloid; NFTs; neurofibrillary tangles; GSK-3β; glycogen synthase-3 kinase; MWM; Morris water maze;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

اثرات محافظتی عصاره های آلپاینا اکسفیللا فورتیوس بر روی مدل حیوانی ناشی از لیپوپلی ساکارید آلزایمر

Protective effects of Alpinae Oxyphyllae Fructus extracts on lipopolysaccharide-induced animal model of Alzheimer's disease

Keywords: AOF; Alpinae Oxyphyllae Fructus; AD; Alzheimer's disease; LPS; lipopolysaccharide; CT; control; MD; model; DPZ; donepezil; TT; total; PE; petroleum ether; CF; chloroform; EA; ethyl acetate; NB; n-butanol; WT; water; MWM; Morris water maze; HE; Hematoxylin

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

ویژگی ها و نتایج داروها برای درمان ترکیبی به عنوان استراتژی چند هدفه ای برای مبارزه با بیماری آلزایمر

Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; β-amyloid peptide; NFTs; neurofibrillary tangles; EOAD; early-onset AD; LOAD; late-onset AD; OMOT; One-molecule-one-target; ROS; reactive oxygen species; CDMT; Combination-drugs-multi-targets; BBB; blood brain barrier; DDT;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

اثر نوروبولوژیک بربرین در برابر عصبی ناشی از فلزات سنگین محیط زیست و بیماری آلزایمر مانند در موش صحرایی

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats

Keywords: Alzheimer's disease; Heavy metals; Berberine; Amyloid-β40/42; Tau protein; Proinflammatory cytokines and In silico analysis; AChE; acetylcholinesterase; AD; Alzheimer's disease; Akt; Protein kinase B; AMPK; 5′ adenosine monophosphate-activated protein

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

پیشرفت اخیر در چارچوب فلزات آلی برای احتیاط و تشخیص بیماری آلزایمر

Recent progress in metal-organic frameworks for precaution and diagnosis of Alzheimer's disease

Keywords: Aβ; amyloid-β peptide; AD; Alzheimer's disease; ASBA; 2-amino-5-sulfobenzoic acid; BDC; 1-4-benzendicarboxylate; BHC; mellitic acid; BIMB; 1,4-bis(1H-imidazol-1-yl)butane; 2,2ˊ-Bipy; 2,2′-Bipyridine; 4,4ˊ-Bipy; 4,4′-Bipyridine; BPTC; 3,3′,5,

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

استرس اکسیداتیو با هیپسفسفوریلاسیون تتو در مواجهه با حافظه 1،2-دی اتیلوبنز باعث اختلال در حافظه می شود

Oxidative stress with tau hyperphosphorylation in memory impaired 1,2-diacetylbenzene-treated mice

Keywords: AD; Alzheimer's Disease; DAB; 1,2-diacetylbenzene; GSK-3β; glycogen synthase kinase-3β; NFTs; neuro fibrillary tangles; PHF; paired helical filament; ROS; reactive oxygen species; 1,2-Diacetylbenzene; Morris Water Maze; Oxidative stress; Tau hyperphos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

توزیع تریروزین کیناز طلایی و تئو فسفریله شده در تیروزین 18 در مدل موش تواوپاتی و در هیپوکامپ انسان

Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus

Keywords: AD; Alzheimer's disease; FTDP-17; frontotemporal dementia with parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; GSK3β; glycogen synthase kinase-3β; NFTs; neurofibrillary tangles; pSyk; spleen tyrosine kinase phosphorylated at t

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

تجمع پروتئین و تولید نوروژنز در بیماریهای نورولوژیکی پیشآهنگی: نمونه هایی از آمیلوئیدوپاتی، تئوپاتی ها و سینوژین پپتیدها

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

Keywords: Aβ; beta-amyloid peptide; AAV; adeno-associated virus; ABAD; amyloid-beta-binding alcohol dehydrogenase; AD; Alzheimer's disease; ALP; autophagy-lysosome pathways; Apaf-1; apoptic protease-activating factor 1; APP; amyloid precursor protein; AICD; APP in

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

نقش اسیدهای چرب اشباع نشده اسیدهای چرب امگا -3 ایکوزاپنتانوئیک و اسید داکوزاگزنئوئیک در درمان افسردگی و بیماری آلزایمر: عمل به صورت جداگانه یا همزمان؟

The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: Acting separately or synergistically?

Keywords: Aβ; amyloid β; AA; arachidonic acid; AD; Alzheimer's disease; ALA; α-linolenic acid; APP; amyloid precursor proteins; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; CSF; cerebral spinal fluid; COX2; cyclooxygenase 2; DHA; docosah

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

استروسیت ها در محافظت از عصب و تولید عصبی: نقش کانکسین 43 و پانکسین 1

Astrocytes in neuroprotection and neurodegeneration: The role of connexin43 and pannexin1

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood-brain barrier; BCAO; bilateral carotid artery occlusion; Cbx; carbenoxolone; CM; conditioned media; Cx43; connexin43; Cxs; connexins; ECM; extracellular matrix; FGF1; fibroblast growth factor; GFAP;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

مکانیسم سلول های بنیادی بتا آمیلوئید 25-35 عصبی در سلول های اولیه مغز استخوان

Mechanism of soluble beta-amyloid 25-35 neurotoxicity in primary cultured rat cortical neurons

Keywords: Aβ25-35; beta-amyloid 25-35; AD; Alzheimer's disease; NFTs; neurofibrillary tangles; Soluble beta-amyloid 25-35; Cell viability; CCK-8; Calcium detection; PI3K-p85 protein;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

توسعه لیگاند های استئوفنون به عنوان عوامل بالقوه نوری برای کولین استراز

Development of acetophenone ligands as potential neuroimaging agents for cholinesterases

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; BuLi; butyl lithium; DTNB; 5,5′-dithiobis 2-nitrobenzoic acid; HPLC; high performance liquid chromatography; HRMS; high resolution mass spectrum; LRMS;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

توسعه داروهای آلزایمر مبتنی بر طراحی مواد مخدر توسط کامپیوتر

Alzheimer's disease drug development based on Computer-Aided Drug Design

Keywords: Alzheimer's disease; Amyloid-β; β-secretases; γ-secretases; Computer-Aided Drug Design; AD; Alzheimer's disease; Aβ1-40; beta-Amyloid isoform 40 amino acids in length; Aβ1-42; beta-Amyloid isoform 42 amino acids in length; NMDA; N-Methyl-d-aspart

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2016 سفارش ترجمه

عصب پس از ضربه مغزی و انسفالوپاتی مزمن

Post-traumatic neurodegeneration and chronic traumatic encephalopathy

Keywords: TDP-43; 43 kDa TAR DNA-binding protein; AD; Alzheimer's disease; APOE ε4; apolipoprotein ε4; Aβ; beta-amyloid; CSF; cerebrospinal fluid; CTE; chronic traumatic encephalopathy; p-tau; hyperphosphorylated tau; mTBI; mild traumatic brain injury; NFTs; ne

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

پیروات مانع توسعه نقص شناختی وابسته به سن در یک مدل موش از بیماری آلزایمر بدون کاهش آسیب شناسی آمیلوئید و تاو

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; NFTs; neurofibrillary tangles; p-tau; hyperphosphorylated tau; ROS; reactive oxygen species; [Zn2 +]i; intraneuronal Zn2 +; [Ca2 +]i; intraneuronal Ca2 +; m.o; month old; m.o.a; months of age; i.p; intraperito

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

خط لوله مواد مخدر در تولید عصبی مبتنی بر مدل موش های ترانس ژنیک بیماری آلزایمر

Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease

Keywords: 7,8-DHF; 7,8-dihydroxyflavone; Aβ; amyloid beta; AchE; acetylcholine-esterase; ABCA1; ATP-binding cassette transporter 1; APP; amyloid precursor protein; Akt; protein kinase B; ApoE; apolipoprotein E; AAV/Aβ; adeno-associated viral vector carrying Aβ c

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β

Keywords: Aβ; Amyloid beta; AD; Alzheimer's disease; ANOVA; Analysis of variance; BBB; Blood-brain barrier; BCA; Bicinchoninic acid; BSA; Bovine serum albumin; COX-2; Cyclooxygenase-2; DAPI; 4′, 6-Diamidine-2′-phenylindole dihydrochloride; DMEM; Dulbecco's m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Imperatorin ameliorates lipopolysaccharide induced memory deficit by mitigating proinflammatory cytokines, oxidative stress and modulating brain-derived neurotropic factor

Keywords: Aβ; amyloid beta; AChE; acetyl cholinesterase; AD; Alzheimer's disease; ANOVA; analysis of variance; BSA; Bovine serum albumin; BDNF; brain derived neurotrophic factor; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Anim

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link

Keywords: 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (Aβ)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells

Keywords: Aβ; Beta amyloid; AD; Alzheimer's disease; ANOVA; Analysis of variance; ATCC; American Tissue Culture Collection; BV-2 cells; Immortalised murine microglial cells; CM; Conditioned media; CNS; Central nervous system; DCM; Dichloromethane; DMEM; Dulbecco's

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells

Keywords: PF; paeoniflorin; OA; okadaic acid; 3-MA; 3-methyladenine; Rapa; rapamycin; LiCl; lithium chloride; AD; Alzhiemer's disease; CAST; Ac-calpastain; CQ; chloroquine; NFTs; neurofibrillary tangles; CaMKII; calcium/calmodulin protein kinase II; MAP2; microtu

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairment

Keywords: Aβ; amyloid beta; AChE; acetyl cholinesterase; AD; Alzheimer's disease; AG; aminoguanidine; AGEs; advanced glycation end products; ANOVA; analysis of variance; AU; arbitrary units; BSA; bovine serum albumin; d-gal; d-galactose; DNP; Donepezil; GSH; red

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies

Keywords: Dihydroactinidiolide; Acetylcholinesterase; Alzheimer's disease; ADME; Amyloid β25-35; Neuro2a cells; AChE; Acetylcholinesterase; AChEI; Acetylcholinesterase Inhibitors; AD; Alzheimer's disease; ADME; Absorption Distribution Metabolism Excretion; NO; N

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome

Keywords: AD; Alzheimer's disease; ANSC; adult neural stem cell; Aβ; amyloid-β protein; CNS; central nervous system; DAMPs; danger-associated molecular patterns; IL-1; interleukin-1; LBs; Lewy bodies; NFTs; neurofibrillary tangles; NLRs; NOD-like receptors; PAMPs

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

High-glucose induces tau hyperphosphorylation through activation of TLR9-P38MAPK pathway

Keywords: DM; diabetes mellitus; DE; diabetic encephalopathy; AD; Alzheimer's disease; NFTs; neurofibrillary tangles; SPs; senile plaques; Aβ; amyloid β-protein; TLR9; toll-like receptor 9; P38MAPK; P38mitogen-activated protein kinase; MAP; microtubule-associated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; AMPAR; AMPA-type glutamate receptor; CNS; central nervous system; FTDP-17; frontotemporal dementia with parkinsonism linked to chromosome 17; GFP; green fluorescent protein; GSK-3β; glycogen synthase kinase-3β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways

Keywords: AD; Alzheimer's disease; Aβ; Amyloid beta; APP; Amyloid precursor protein; NFTs; Neurofibrillary tangles; BACE1; β-secretase 1; TNF-α; Tumor necrosis factor; iNOS; Inducible nitric oxide synthase; NSAIDs; Non-steroidal anti-inflammatory drugs; PPARγ;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Electrochemical studies of tau protein-iron interactions-Potential implications for Alzheimer's Disease

Keywords: CD; circular dichroism spectroscopy; CV; cyclic voltammetry; DPV; differential pulse voltammetry; GSK3β; Glycogen synthase kinase 3-β; Lip-NHS; Lipoic acid N-hydroxysuccinimide ester; NFTs; neurofibrillary tangles; n-tau; native tau; p-tau; phosphoryl

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β peptide; FTDP-17; frontotemporal dementia and Parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; mTOR; mammalian target of rapamycin; NFTs; neurofibrillary tangles; p70S6K; S6 kinases; PI3K;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

TREMs in Alzheimer's disease: Genetic and clinical investigations

Keywords: AD; Alzheimer's disease; TREM; Triggering receptor expressed on myeloid cells; TREML; TREM like transcript; NHD; Nasu-Hakola disease; NFTs; neurofibrillary tangles; p-tau; hyperphosphorylated tau; GWAS; genome-wide association studies; sTREM2; soluble f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Ligand autoradiographical quantification of histamine H3 receptor in human dementia with Lewy bodies

Keywords: DLB; Dementia with Lewy Bodies; AD; Alzheimer's Disease; ADHD; attention deficit hyperactivity disorder; NFTs; neurofibrillary tangles; PM; post mortem delay; RαMHA; R-α-methylhistamine; MMSE; Mini Mental State Examination; UPDRS; Unified Parkinson Di

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Impaired burrowing is the most prominent behavioral deficit of aging htau mice

Keywords: 4R; 4-repeat; AD; Alzheimer's disease; ANOVA; analysis of variance; MAP1A; microtubule-associated protein 1A; mtau−/−; murine tau knockout; NFTs; neurofibrillary tangles; RIPA; radioimmunoassay precipitation; htau; tau knock-out; cognition; behavior

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease

Keywords: PICALM; Tau; NFTs; Alzheimer's disease; Pick disease; Progressive supranuclear palsy; Corticobasal degeneration; FTLD-MAPT; FTLD-TDP; Diffuse Lewy body disease; Autophagy; LC3; Beclin-1;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11 month old APP/PS1 transgenic mice: A Western blot study

Keywords: AD; Alzheimer's disease; Aβ; β-Amyloid; NFTs; neurofibrillary tangles; APP; amyloid precursor protein; GSK3β; glycogen synthase kinase-3β; BACE1; precursor protein-cleaving enzyme 1; FZS; fuzhisan; Glycogen synthase kinase-3β (GSK3β); Fuzhisan (FZS)

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology

Keywords: AD; Alzheimer´s disease; Aβ; amyloid-β peptide; MV; membrane vesicles; NFTs; neurofibrillary tangles; PMCA; plasma membrane Ca2+-ATPase; SERCA; sarco(endo)plasmic reticulum Ca2+-ATPase; SPCA; secretory pathway Ca2+-ATPase; Tau; Calcium; PMCA; Aging; Al

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Herbs to curb cyclic nucleotide phosphodiesterase and their potential role in Alzheimer's disease

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; AD; Alzheimer's disease; PDE; phosphodiesterases; Aβ; amyloid beta; NFTs; neurofibrillary tangles; FAD; familial Alzheimer's disease; SAD; sporadic Alzheimer's disease; APP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease

Keywords: AD; Alzheimer's disease; APP; Aβ (β-Amyloid) precursor protein; BACE1; β-amyloid cleavage enzyme 1; miRs; MicroRNAs; NFTs; neurofibrillary tangles; 3′UTRs; 3′-untranslated regions; UCHL1; ubiquitin carboxy-terminal hydrolase L1; miR-922; UCHL1; p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; BBB; blood-brain barrier; BSA; bovine serum albumin; GSK-3β; glycogen synthase kinase-3β; GST; glutathione S-transferase; ICV; intracerebroventricularly; NFTs; neurofibrillary tangles; Nrf2; nuclear factor-E

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Pterostilbene attenuates lipopolysaccharide-induced learning and memory impairment possibly via inhibiting microglia activation and protecting neuronal injury in mice

Keywords: LPS; lipopolysaccharide; DCX; Doublecortin; AD; Alzheimer's disease; Ab; Amyloid b; TLR; toll-like receptor; NO; nitric oxide; TNF-a; tumor necrosis factor-a; IL-6; interleukin 6; LTP; long-term potentiation; NFTs; neurofibrillary tangles; APP; amyloid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

Keywords: AMPK; AMP-activated protein kinase; STAT; activator of transcription; AGE; advanced glycation end products; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β peptide; ACE; angiotensin converting enzyme; Ang I; angiotensin I; AR-II;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress conditions

Keywords: AD; Alzheimer's disease; SPs; senile plaques; NFTs; neurofibrillary tangles; CAA; cerebrovascular amyloid angiopathy; Aβ; amyloid-β peptides; sHsp; small heat shock protein; SpHsp16.0; sHsp from fission yeast Schizosaccharomyces pombe; Amyloid-β; Amy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; 4EBP1; eukaryotic translation initiation factor 4E (eIF-4E)-binding protein-1; FOXO; Forkhead box-O class transcription factors; FMRP; Fragile-X mental retardation protein; GSK3β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Decisive role of Reelin signaling during early stages of Alzheimer's disease

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; AON; anterior olfactory nucleus; ApoER2; apolipoprotein E receptor 2; APP; amyloid precursor protein; Dab-1; Disabled-1; GWA; genome-wide association; LTP; long term potentiation; MCI; mild cognitive impairmen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events

Keywords: iPS cells; induced pluripotent stem cells; hiPS-C4; hiPS cell line UC C0406 iPS-C4; ES cells; embryonic stem cells; NPCs; neural progenitor cells; CCEs; cell cycle events; Aβ; β-amyloid; NFTs; neurofibrillary tangles; APP; amyloid precursor protein; AD;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons

Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; EGCG; (−)-epigallocatechin-3-gallate; BAG2; BCL2-associated athanogene 2; LAMP1; lysosomal-associated membrane protein 1; NFTs; neurofibillary tangles; BACE1; beta-site APP cleaving enzyme-1; APP; amyloid prec

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric β-amyloid 1-42-induced neurotoxicity

Keywords: AD; Alzheimer's disease; Aβ; β-amyloid peptide; APP; amyloid precursor protein; SPs; senile plaques; NFTs; neurofibrillary tangles; ROS; reactive oxygen species; COSs; chitosan oligosaccharides; Aβ42; β-amyloid fragments 1-42; HFIP; 1,1,1,3,3,3-hexafl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Dissecting the molecular mechanism by which NH2htau and Aβ1-42 peptides impair mitochondrial ANT-1 in Alzheimer disease

Keywords: AA; antimycin A; Aβ; β-amyloid; AD; Alzheimer disease; ANT-1; adenine nucleotide translocator-1; Ap5A; P1,P5-Di(adenosine-5′)penta-phosphate; ATP D.S.; ATP detecting system; ATR; atractyloside; β-OH; β-hydroxybutyrate; CGCs; cerebellar granule cells

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه