دانلود مقالات ISI درباره Ngs + ترجمه فارسی

RNA editing independently occurs at three mir-376a-1 sites and may compromise the stability of the microRNA hairpin

Keywords: A; adenosine; ADAR; adenosine deaminase; Cq; quantification cycle; dsRNA; double-stranded RNA; G; guanosine; I; inosine; MFE; minimum free energy; mRNA; messenger RNA; miRNA; microRNA; NGS; next generation sequencing; nt; nucleotide; RT-qPCR; real time qu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Large Cell Neuroendocrine Carcinoma Transformation and EGFR-T790M Mutation as Coexisting Mechanisms of Acquired Resistance to EGFR-TKIs in Lung Cancer

Keywords: EGFR; epidermal growth factor receptor; LCNEC; large cell neuroendocrine carcinoma; NGS; next-generation sequencing; NSCLC; non-small cell lung cancer; SCLC; small cell lung cancer; TKI; tyrosine kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical and genetic characteristics of 17 Chinese patients with glycogen storage disease type IXa

Keywords: GSD; glycogen storage disease; PhK; phosphorylase kinase; XLG; X-linked liver glycogenosis; ALT; aminotransferase; AST; aspartate aminotransferase; CR; serum creatinine; TC; total cholesterol; TG; total triglyceride; CK; creatine kinase; NGS; next-generat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

NPY up-regulation in the tadpole brain of Euphlyctis cyanophlyctis during osmotic stress

Keywords: ADH; vasopressin; Al; amygdala lateralis; Am; amygdala medialis; CNS; central nervous system; CRH; corticotropin-releasing hormone; DP; dorsal pallium; IR; infundibular recess; LP; lateral pallium; ME; median eminence; MP; medial pallium; NCER; nucleus ce

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleThe high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians

Keywords: AML; acute myeloid leukemia; BM; bone marrow; FISH; fluorescence in situ hybridization; MDS; myelodysplastic syndrome; MPN; myeloproliferative neoplasm; NGS; next generation sequencing; RAEB; refractory anemia with excess blasts; RARS; refractory anemia w

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperInter-relationship between PD-L1 expression and clinic-pathological features and driver gene mutations in pulmonary sarcomatoid carcinomas

Keywords: PSC; pulmonary sarcomatoid carcinoma; NSCLC; non-small cell lung cancer; NGS; next-generation sequencing; Pulmonary sarcomatoid tumor; Pulmonary carcinosarcoma; PD-L1; Immunotherapy; Immunohistochemistry; Mutational burden;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling

Keywords: aa; amino acid; BWA; Burrows-Wheeler aligner; CaM; calmodulin; CPR; cardiopulmonary resuscitation; DNA; deoxyribonucleic acid; ECG; electrocardiogram; GOF; gain of function; KCNE1; potassium voltage-gated channel subfamily E member 1; Kv7.1; voltage-gated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation

Keywords: Vascular smooth muscle cells; Calciprotein particles; Sulfide; H2S/HS−; NQO1; VSMC; vascular smooth muscle cells; CKD; chronic kidney disease; CPP; calciprotein particles; H2S; hydrogen sulfide; NaHS; sodium hydrosulfide; NGS; next generation sequencing

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

USP7 inhibitors, downregulating CCDC6, sensitize lung neuroendocrine cancer cells to PARP-inhibitor drugs

Keywords: L-NET; CCDC6; USP7; NGS; P5091; PARP-Inhibitors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Draft genome sequence of an O25:H4-ST131 Escherichia coli harbouring blaNDM-1 on an IncHI3 plasmid: A first report

Keywords: NDM; Carbapenemase; Next-generation sequencing; NGS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Endocytosis in primary mesenchyme cells during sea urchin larval skeletogenesis

Keywords: PMC; primary mesenchyme cell; SMP; spicule matrix protein; WGA; wheat germ agglutinin; FNS; filtered natural seawater; NGS; normal goat serum; GPI; glycosylphosphatidylinositol; Calcium; Endocytosis; Calcein; msp130; Endoskeleton; Sea urchin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes

Keywords: CI; confidence interval; CPM; counts per million; CSF; cerebrospinal fluid; dPCR; digital PCR; HDL; high-density lipoprotein; NGS; next-generation sequencing; microRNA; Small RNA; Exosome; Cerebrospinal fluid; Next-generation sequencing; Digital PCR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment

Keywords: MM; multiple myeloma; MGUS; monoclonal gammopathy of undetermined significance; SMM; smoldering multiple myeloma; NGS; next-generation sequencing; PC; plasma cell; GFP; green fluorescent protein; tdT; tandem dimer tomato; PCR; polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original Research ArticleSecretory pathway optimization of CHO producer cells by co-engineering of the mitosRNA-1978 target genes CerS2 and Tbc1D20

Keywords: CHO; Chinese Hamster Ovary; ER; endoplasmic reticulum; NGS; next generation sequencing; miRNA; microRNA; HSA; human serum albumin; hsa-miR; Homo sapiens miRNA; mitosRNA; mitochondrial genome-encoded small RNA; siRNA; small-interfering RNA; shRNA; short ha

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Determinants of orofacial clefting II: Effects of 5-Aza-2′-deoxycytidine on gene methylation during development of the first branchial arch

Keywords: 1-BA; first branchial arch; AzaD; 5-Aza-2′-deoxycytidine; CGI; CpG island; CM; complete media; CP; cleft palate; CL/P; cleft lip with or without cleft palate; GD; gestational day; IPA; ingenuity pathway analysis; MCS; MethylCap-sequencing; MEMM; mouse e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Comparative genomic analysis of two heat-resistant Rhodobacter capsulatus mutants with different hydrogen production levels reveals mutations related to hydrogen production

Keywords: Next generation sequencing; Biohydrogen; Bacterial genomics; Purple nonsulfur bacteria; PII uridylyl-transferase; Hydrogen; H2; Nitrogen; N; Quantitative reverse transcription polymerase chain reaction; qRT-PCR; Next generation sequencing; NGS; Calvin-B

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

HLA-E regulatory and coding region variability and haplotypes in a Brazilian population sample

Keywords: HLA-E, 3′ untranslated region; Promoter; Variability; Next generation sequencing; Polymorphism; ABC MRP7; ATP-binding cassette transporter multidrug resistance associated protein; bp; Base pairs; DNA; Deoxyribonucleic acid; EBV; Epstein-Barr virus; HCMV

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters

Keywords: Brugada syndrome; hiPSC-cardiomyocytes; Ajmaline; INa; IKr; Activation-recovery interval; AP; Action Potential; APD; Action Potential Duration; Br1; Brugada Type 1 ECG; BrS; Brugada Syndrome; cFPD; Corrected Field Potential Duration (Bazett's formula); CM

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

HLA-G variability and haplotypes detected by massively parallel sequencing procedures in the geographicaly distinct population samples of Brazil and Cyprus

Keywords: HLA-G; Next generation sequencing; NGS; Massive parallel sequencing; Brazil; Cyprus; Haplotypes; Variability; Polymorphisms;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacogenomics: Precision Medicine and Drug Response

Keywords: CYP; cytochrome P450; EHR; electronic health record; eMERGE; Electronic Medical Records and Genomics; GWAS; genome-wide association study; NGS; next-generation sequencing; NIH; National Institutes of Health; ns; nonsynonymous; PGRN; Pharmacogenomics Resea

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

BAL31-NGS approach for identification of telomeres de novo in large genomes

Keywords: Telomere; NGS; BAL31; RepeatExplorer; Tandem Repeats Finder; Tandem Repeats Merger;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

An ELISA protocol to improve the accuracy and reliability of serological antibody assays

Keywords: ELISA; enzyme-linked immunosorbent assay; BL; blank; BG; background; OD; optical density; NGS; normal goat serum; RA; rheumatoid arthritis; NL; normal; CCP; cyclic citrullinated peptide; LPS; lipopolysaccharide; ELISA; Antibody Assay; ChonBlock™; False

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Searching for active mobile genetic elements in dsRNA fraction of Pinus sylvestris having witches broom abnormalities

Keywords: NGS; dsRNA; Mobile genetic elements;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

A case study of tuning MapReduce for efficient Bioinformatics in the cloud

Keywords: Hadoop; YARN; Parameter optimization; K-mer counting; NGS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Complete genome sequence of Ostreid herpesvirus type 1 µVar isolated during mortality events in the Pacific oyster Crassostrea gigas in France and Ireland

Keywords: Ostreid herpesvirus-1 µVar; Complete genome; Indels; NGS; Crassostrea gigas;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Impact and influence of “omics” technology on hyper tension studies

Keywords: Hypertension; Blood pressure; Genomics; Proteomics; NGS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Neurology Individualized Medicine: When to Use Next-Generation Sequencing Panels

Keywords: ACMG; American College of Medical Genetics and Genomics; bp; base pair; CNV; copy number variation; HGMD; Human Gene Mutation Database; NGS; next-generation sequencing; OMIM; Online Mendelian Inheritance in Man; WES; whole-exome sequencing; WGS; whole-gen

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region

Keywords: HIV-1; Vaccine; gp41; MPER; Rabbit; Neutralizing antibody; Antibody maturation; Next-generation sequencing; NGS;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Bacteriophage SPP1 pac Cleavage: A Precise Cut without Sequence Specificity Requirement

Keywords: dsDNA; double-stranded DNA; TerS; small subunit of the terminase; TerL; large subunit of the terminase; NGS; next-generation sequencing; DBD; DNA-binding domain; bacteriophage; genome recognition; DNA packaging; pac cleavage; terminase;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

A Child with Epidermolytic Ichthyosis from a Parent with Epidermolytic Nevus: Risk Evaluation of Transmission from Mosaic to Germline

Keywords: EN; epidermolytic nevus; EI; epidermolytic ichthyosis; gDNA; genomic DNA; NGS; next-generation sequencing;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Detection of viromes of RNA viruses using the next generation sequencing libraries prepared by three methods

Keywords: AIV; avian influenza virus; IBV; infectious bronchitis virus; NDV; Newcastle disease virus; NGS; next-generation sequencing; PBS; phosphate buffered solution; PCR; polymerase chain reaction; PGM; Personal Genome Machine; RT; reverse transcription; SISPA;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Phospholamban immunostaining is a highly sensitive and specific method for diagnosing phospholamban p.Arg14del cardiomyopathy

Keywords: ACM; Arrhythmogenic cardiomyopathy; ARVC; Arrhythmogenic right ventricular cardiomyopathy; DCM; Dilated cardiomyopathy; IHC; Immunohistochemistry; LVAD; Left ventricular assist device; NGS; Next-generation sequencing; PLN; Phospholamban; RVEMB; Right vent

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

The clinical role of circulating free tumor DNA in gastrointestinal malignancy

Keywords: cfDNA; circulating cell-free DNA; ctDNA; circulating cell-free tumor-derived DNA; NGS; next generation sequencing; ALU; short interspersed nucleic acid element repeats; LINE1; long interspersed nucleotide elements; RT-PCR; reverse transcriptase polymerase

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

An in vitro Model to Mimic Selection of Replication-Competent HIV-1 Intersubtype Recombination in Dual or Superinfected Patients

Keywords: RT; reverse transcriptase; CRF; circulating recombinant form; URF; unique recombinant form; C1; conserved domain 1; NGS; next generation sequencing; FRP; functional recombinant production; sgRNA; subgenomic RNA; nfl; near full-length; VSV-G; vesicular sto

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of pig-specific Cryptosporidium species in mixed infections using Illumina sequencing technology

Keywords: Cryptosporidium; Mixed infections; NGS; Identification;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis

Keywords: unexplained polyposis; mutation; Wnt signaling; colorectal carcinogenesis; NGS; next-generation sequencing;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility

Keywords: mAb; monoclonal antibody; pAbs; polyclonal antibodies; IHC; immunohistochemistry; ELISA; enzyme-linked immunosorbent assay; NGS; next-generation sequencing; aa; amino acid; Ig; immunoglobulin; Fz; frizzled; Kr; kringle; BC; breast cancer; CAR-T; chimeric

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Differential gene expressions of innate immune related genes of the Asian honeybee, Apis cerana, latently infected with sacbrood virus

Keywords: Apis cerana; Sacbrood virus; Transcriptome; NGS; Innate immune;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Multiplex PCR and NGS-based identification of mRNA splicing variants: Analysis of BRCA1 splicing pattern as a model

Keywords: ASV(s); alternative splicing variant(s); mPCR; multiplex PCR; NGS; next generation sequencing; SAS; splice acceptor shift; SDS; splice donor shift; VUS; variant of unknown clinical significance; Alternative splicing; mRNA splicing variant; BRCA1; Multiple

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted Next Generation Sequencing in patients with Myotonia Congenita

Keywords: Myotonia Congenita; NGS; CLCN1; Thomsen disease; Becker disease;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

High-throughput sequencing of the entire genomic regions of CCM1/KRIT1, CCM2 and CCM3/PDCD10 to search for pathogenic deep-intronic splice mutations in cerebral cavernous malformations

Keywords: Cerebral cavernous malformation; CCM1; CCM2; CCM3; Deep-intronic variants; NGS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Two novel mutations in the PPIB gene cause a rare pedigree of osteogenesis imperfecta type IX

Keywords: cDNA; DNA complementary to RNA; NGS; next-generation sequencing; OI; osteogenesis imperfecta; OI-IX; osteogenesis imperfecta type IX; PCR; polymerase chain reaction; PGD; preimplantation genetic diagnosis; PTC; premature termination codon; RTQ-PCR; real-t

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Phylogenetic position of the rainbow sardine Dussumieria (Dussumieriidae) and its bearing on the early evolution of the Clupeoidei

Keywords: A; adenosine; C; cytidine; G; guanosine; T; thymidine; PCR; polymerase chain reaction; ML; maximum likelihood; 16S rRNA; 16S ribosomal RNA gene; 12S rRNA; 12S ribosomal RNA gene; tRNA; transfert RNA; NGS; Mitogenome; Fish; Clupeiformes; Evolution; Phyloge

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of a novel splicing mutation within SLC17A8 in a Korean family with hearing loss by whole-exome sequencing

Keywords: ADNSHL; autosomal dominant non-syndromic hearing loss; CRISPR; clustered regularly interspaced short palindromic repeats; CV; consensus values; DNA; deoxyribonucleic acid; HHL; hereditary hearing loss; HL; hearing loss; HSF; Human Splicing Finder; IHCs; i

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Gene-Targeted Next Generation Sequencing Identifies PNPLA1 Mutations in Patients with a Phenotypic Spectrum of Autosomal Recessive Congenital Ichthyosis: The Impact of Consanguinity

Keywords: ARCI; autosomal recessive congenital ichthyosis; bp; base pair; NGS; next generation sequencing;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Identification and molecular cloning of novel transcripts of the human kallikrein-related peptidase 10 (KLK10) gene using next-generation sequencing

Keywords: Kallikreins; Alternative splicing; Serine proteases; NGS; Splice variant;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Potential Resistance Mechanisms Revealed by Targeted Sequencing from Lung Adenocarcinoma Patients with Primary Resistance to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs)

Keywords: Lung adenocarcinoma; EGFR TKIs; NGS; Primary resistance;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Buccal swab genomic DNA fragmentation predicts likelihood of successful HLA genotyping by next-generation sequencing

Keywords: HLA; NGS; gDNA fragmentation; Buccal swab;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Mutation analysis of TRPS1 gene including core promoter, 5′UTR, and 3′UTR regulatory sequences with insight into their organization

Keywords: Alternative splicing; Chromosomal rearrangement; Mutation; NGS; Promoter;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Dystrophic Epidermolysis Bullosa: COL7A1 Mutation Landscape in a Multi-Ethnic Cohort of 152 Extended Families with High Degree of Customary Consanguineous Marriages

Keywords: DEB; dystrophic epidermolysis bullosa; EB; epidermolysis bullosa; Mb; mega-base pair; NGS; next-generation sequencing; RDEB; recessive dystrophic EB; SNP; single nucleotide polymorphism; WES; whole-exome sequencing;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه