دانلود مقالات ISI درباره Nrf2 + ترجمه فارسی

Magnolia officinalis (Hou Po) bark extract stimulates the Nrf2-pathway in hepatocytes and protects against oxidative stress

Keywords: ARE; antioxidant response element; GCLC; glutamate-cysteine ligase catalytic subunit; Hepa1c1c7; murine hepatoma cells; HepG2; human hepatoma cells; HMOX1; heme oxygenase-1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; Keap1; Kelch-like ECH-associated

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Redox signaling: An evolution from free radicals to aging

Keywords: Oxidative stress; Redox signaling; Superoxide; Hydrogen peroxide; NADPH oxidase; AP-1; Nrf2; Aging; Homeostasis; Antioxidant; Air pollution; Thiolate; Glutathione;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation

Keywords: ALI; acute lung injury; APCs; antigen-presenting cells; ARE; antioxidant responsive element; Bach1; Broad complex-Tramtrack-Bric-a-brac (BNB) and Cap'n'collar (CNC) homolog 1; BAL; bronchoalveolar lavage; BR; bilirubin-IXα; BV; biliverdin-IXα; BVR;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy

Keywords: CKD; Chronic kidney disease; CRF; Chronic renal failure; RA; Rheumatoid arthritis; ON; Obstructive nephropathy; ROS; Reactive oxygen species; UUO; Unilateral ureteral obstruction; HE; Hematoxylin and eosin; SIN; Sinomenine; LPS; Lipopolysaccharide; 3-MA;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface

Keywords: PTS; pterostilbene; ARE; antioxidant responsive element; Keap1; Kelch-like ECH-associated protein-1; Nrf2; nuclear factor erythroid 2-related factor 2; MIN6 cells; mouse insulinoma-6 cells; MD; molecular dynamics; RMSD; root-mean square deviation; MM-GBSA

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

α-Lipoic acid protects against the cytotoxicity and oxidative stress induced by cadmium in HepG2 cells through regeneration of glutathione by glutathione reductase via Nrf2/ARE signaling pathway

Keywords: α-Lipoic acid; Cadmium; Glutathione; Glutathione reductase; Nrf2;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

The protective mechanism of docosahexaenoic acid in mouse model of Parkinson: The role of heme oxygenase

Keywords: Heme oxygenase; Docosahexaenoic acid; Nrf2; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin

Keywords: CE; cornified cell envelope; EDC; epidermal differentiation complex; FLG; filaggrin; Gly/Ser; glycine/serine; Keap1; Kelch-like ECH-associated protein 1; Lce1; late cornified envelope 1; LKO; Lor knockout; LOR; loricrin; Nrf2; NF-E2-related factor 2; tBHQ

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

Keywords: Nrf2; Keap1; GSK-3; PKB/Akt; PI3K; PTEN; β-TrCP; ARE; antioxidant response element; tBHQ; tert-butyl hydroquinone; bZIP; basic-region leucine zipper; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; CNC; cap'n'collar; Cul1; cullin-1; Cu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1

Keywords: Luteolin; Pseudorabies virus (PRV); STAT1/3; NF-κB; Nrf2; HO-1;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic modifications of triterpenoid ursolic acid in activating Nrf2 and blocking cellular transformation of mouse epidermal cells

Keywords: UA; Nrf2; JB6 P+; DNMT; HDAC; Skin cancer;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

6-Shogaol, an active compound of ginger, alleviates allergic dermatitis-like skin lesions via cytokine inhibition by activating the Nrf2 pathway

Keywords: 6-Shogaol; 2,4-Dinitrochlorobenzene; Allergic dermatitis; Antiinflammation; Antioxidant; Nrf2;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy

Keywords: Diabetic nephropathy; PPARα agonist; FGF21; Nrf2; Type 1 diabetes; Oxidative stress; Antioxidants;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway

Keywords: SPRC; S-propargyl-cysteine; CSE; cystathionine γ-synthase; FLS; fibroblast-like synoviocytes; AIA; adjuvant-induced arthritis; Nrf2; nuclear factor erythroid-2-related factor 2; ARE; antioxidant response element; Keap1; kelch-like ECH-associated protein

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Glucagon-like peptide-1 improves beta-cell antioxidant capacity via extracellular regulated kinases pathway and Nrf2 translocation

Keywords: DCFH; dichorofluorescin; GLP-1; glucagon-like peptide-1; GPx; glutathione peroxidase; GR; glutathione reductase; GSIS; glucose-stimulated insulin secretion; GSH; reduced glutathione; Nrf2; nuclear transcription factor erythroid 2p45-related factor; ROS; r

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells

Keywords: PM2.5; DDAH1; Nrf2; iNOS; ROS;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R

Keywords: I/R; Ischemia/reperfusion; NF-κB; Factor-kappa-B; Nrf2; Nuclear factor-erythroid-related factor-2; MCAO; Middle cerebral artery occlusion; BBB; Blood brain barrier; WHO; World Health Organization; MMPs; Matrix metalloproteinase; CCA; Common carotid arter

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators

Keywords: ARE; antioxidant response element; br; broad; 6G; [6]-gingerol; GFP; green fluorescent protein; gstp 1; glutathione S-transferase pi 1; hpf; hours postfertilization; Keap1; Kelch-like ECH-associated protein 1; LC/MS; liquid chromatography-mass spectrome

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling

Keywords: Sevoflurane; Postconditioning; Diabetes; Nrf2; Brg1; HO-1;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway

Keywords: PFOS; Nrf2; Pparγ; Adipogenesis; Glucose uptake; ARE;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages

Keywords: AA-5-HT; arachidonoyl serotonin; AEA; arachidonoyl ethanolamide (anandamide); COX-2; cyclooxygenase 2; DHA; docosahexaenoic acid (22:6n-3); DHA-5-HT; docosahexaenoyl serotonin; DHEA; docosahexaenoyl ethanolamine; EPA-5-HT; eicosapentaenoyl serotonin; FAA;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Concomitant ingestion of lactic acid bacteria and black tea synergistically enhances flavonoid bioavailability and attenuates d-galactose-induced oxidative stress in mice via modulating glutathione antioxidant system

Keywords: Black tea; Flavonoid bioavailability; LAB fermentation; Oxidative stress; Glutathione; Nrf2;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Novel triterpenoid AECHL-1 induces apoptosis in breast cancer cells by perturbing the mitochondria-endoplasmic reticulum interactions and targeting diverse apoptotic pathways

Keywords: AECHL-1; Ailanthus excelsa chloroform extract-1; ER; Endoplasmic reticulum; PERK; Protein Kinase R-like ER kinase; eIF2α; eukaryotic Initiation Factor 2α; ROS; Reactive Oxygen Species; Nrf2; Nuclear factor (erythroid-derived 2)-like factor 2; GSH; Gluta

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Circadian modulation of proteasome activity and accumulation of oxidized protein in human embryonic kidney HEK 293 cells and primary dermal fibroblasts

Keywords: ARE; antioxidant response element; BMAL1 or ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1; CLOCK; circadian Locomotor Output Cycles Kaput; ChT-L; chymotrypsin-like; CRY; cryptochrome; DCFDA; 2,7- dichlorofluorescein diacetate; DNPH;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis

Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH associated protein 1; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; MTT; 3-(4,5-di

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes

Keywords: tBHQ; tert-butylhydroquinone; MDA; malondialdehyde; SOD; superoxide dismutase; CAT; catalase; NRF2; nuclear factor E2-related factor 2; HO-1; heme oxygenase-1; NQO1; NAD(P)H: quinine oxidoreductase 1; r-GCL; glutamate-cysteine ligase; Bcl-2; B-cell lympho

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells

Keywords: ADAM19; a disintegrin and metalloproteinase 19; AP-1; activator protein-1; ARE; antioxidant response element; BSP; bisulfite sequencing PCR; CA9; carbonic anhydrase IX; CIH; chronic intermittent hypoxia; COX-2; cyclooxygenase-2; DCF; 2',7'-dichlorofluores

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Pomegranate protects against arsenic-induced p53-dependent ROS-mediated inflammation and apoptosis in liver cells

Keywords: Arsenic; Hepatotoxicity; Pomegranate; Apoptosis; p53; Nrf2;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2016 سفارش ترجمه

Heme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunction

Keywords: PI; protease inhibitors; ROS; reactive oxygen species; HO-1; heme oxygenase-1; CO; carbon monoxide; CORM2; carbon monoxide releasing molecule-2; iCORM2; inactivated carbon monoxide releasing molecule-2; CM-H2DCFDA; 5-(and-6)-chloromethyl-2,7-dichlorodihyd

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism

Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2016 سفارش ترجمه

Gleditsia species: An ethnomedical, phytochemical and pharmacological review

Keywords: AFGS; the ethanol extract from the anomalous fruits of Gleditsia sinensis Lam.; ALI; acute lung injury; AML; acute myelogenous leukemia; AP-1; activator protein-1; ARDS; acute respiratory distress syndrome; bFGF; basic fibroblast growth factor; CDK; cycli

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2016 سفارش ترجمه

Role of NF-E2-related factor 2 in neuroprotective effect of l-carnitine against high glucose-induced oxidative stress in the retinal ganglion cells

Keywords: Diabetic retinopathy; Antioxidant defense; Nrf2; Keap-1; l-Carnitine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of the Nrf2 defense pathway contributes to neuroprotective effects of phloretin on oxidative stress injury after cerebral ischemia/reperfusion in rats

Keywords: Phloretin; Cerebral ischemia/reperfusion; SOD; MDA; GSH-Px; Nrf2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Neopterin as a potential cytoprotective brain molecule

Keywords: Neopterin; Cytoprotective effects; Astrocytes; Nrf2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Indole-3-carbinol as inhibitors of glucocorticoid-induced apoptosis in osteoblastic cells through blocking ROS-mediated Nrf2 pathway

Keywords: Osteoporosis; Apoptosis; Indole-3-carbinol; ROS; Nrf2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

Keywords: Cysteine targeting; Keap1; NQO1; Nrf2; Reversible covalent drug;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1

Keywords: PF-4708671; p70 ribosomal S6 kinase 1 (S6K1); p62; Autophagy; Nuclear factor erythroid 2-related factor 2 (Nrf2); Kelch-like ECH-associated protein 1 (Keap1); GSTA1; glutathione S-transferase A1; Keap1; Kelch-like ECH-associated protein 1; MEF; mouse embr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effect of forsythiaside A on lipopolysaccharide/d-galactosamine-induced liver injury

Keywords: Forsythiaside; Lipopolysaccharide (LPS); Nrf2; NF-κB; Acute liver injury

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Myrosinase-treated glucoerucin is a potent inducer of the Nrf2 target gene heme oxygenase 1 - studies in cultured HT-29 cells and mice

Keywords: Glucoerucin; Heme oxygenase 1; Nrf2; Glucosinolates; Myrosinase; MAPK;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

One-week administration of hydroxytyrosol to humans does not activate Phase II enzymes

Keywords: Hydroxytyrosol; Inflammation; Phase II enzymes; Nrf2; Cardiovascular disease; Mediterranean diet

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A protective mechanism of licorice (Glycyrrhiza uralensis): Isoliquiritigenin stimulates detoxification system via Nrf2 activation

Keywords: Licorice; Glycyrrhiza uralensis; Isoliquiritigenin; Nrf2; Detoxification;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Associate Editor: P. MolenaarActivation of endogenous antioxidants as a common therapeutic strategy against cancer, neurodegeneration and cardiovascular diseases: A lesson learnt from DJ-1

Keywords: DJ-1; Endogenous antioxidant; Mechanism-oriented therapy; Disease-oriented therapy; ASK1; apoptosis signal regulating kinase; JNK; Jun N-terminal kinase; NQO1; NAD(P)H:quinone oxidoreductase 1; Nrf2; nuclear factor erythroid 2-related factor; p53; tumor p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A fast Resazurin-based live viability assay is equivalent to the MTT-test in the KeratinoSens assay

Keywords: LLNA; local lymph node assay; Nrf2; nuclear factor-erythroid 2-related factor 2; NRU; neutral red uptake assay; PB; PrestoBlue®; MTT; (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide = thiazolyl blue tetrazolium bromide; SDS; sodium dodecy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Resveratrol dimers, nutritional components in grape wine, are selective ROS scavengers and weak Nrf2 activators

Keywords: Resveratrol oligomer; Parthenocissin A; Quadrangularin A; Pallidol; Singlet oxygen; Nrf2; ARE;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Potential drugs which activate nuclear factor E2-related factor 2 signaling to prevent diabetic cardiovascular complications: A focus on fumaric acid esters

Keywords: Nrf2; Diabetic complications; Oxidative stress; Dimethyl fumarate; Bardoxolone; Sulforaphane

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Dihydroquercetin (DHQ) ameliorated concanavalin A-induced mouse experimental fulminant hepatitis and enhanced HO-1 expression through MAPK/Nrf2 antioxidant pathway in RAW cells

Keywords: Antioxidant; ConA; DHQ; Hepatitis; Mitogen-activated protein kinases; HO-1; Nrf2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Impact of nuclear factor erythroid-derived 2–like 2 and p62/sequestosome expression on prognosis of patients with gliomas

Keywords: Gliomas; Nrf2; p62; Survival; Prognosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effect of oroxylin A against lipopolysaccharide and/or D-galactosamine–induced acute liver injury in mice

Keywords: Oroxylin A; LPS; Nrf2; TLR4; NF-κB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه