Keywords: OSBP; ORP4; ORP5; ORP8; Cancer; Metastasis; Cell signalling;
مقالات ISI (ترجمه نشده)
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Keywords: ABPM; ambulatory blood pressure monitoring; ADBP; ambulatory diastolic blood pressure; ASBP; ambulatory systolic blood pressure; CH; combined systolic/diastolic hypertension; eGFR; estimated glomerular filtration rate; ISH; isolated systolic hypertension;
Keywords: CSR; complete spatial randomness; EM; electron microscopy; FAPP1; four-phosphate-adaptor protein 1; FRAP; fluorescence recovery after photobleaching; GFP; green fluorescent protein; GST; glutathione S-transferase; IMP; intramembrane particle; INPP5E; inos
Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
Keywords: FAPP1; four-phosphate-adaptor protein 1; GFP; green fluorescent protein; OSBP; oxysterol-binding protein; OSH; oxysterol-binding protein homologs; P4M; PtdIns(4)P binding of SidM; PtdIns(4)P; phosphatidylinositol 4-phosphate; PtdIns(4,5)P2; phosphatidylin
Keywords: ABPP; activity-based protein profiling; ALPS; amphipathic lipid packing sensor; CERT; ceramide transport protein; CG; coarse-grained; DESRES; D.E. Shaw research; DMS; DESRES molecular structure; EM; electron microscopy; EPR; electron paramagnetic resonanc
Keywords: Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti
Keywords: CERT; ceramide transfer protein; CETP; cholesteryl ester transfer protein; ER; endoplasmic reticulum; FABP; fatty acid-binding protein; FFAT; diphenylalanine in an acidic tract; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GLs;
Keywords: CERT; ceramide transfer protein; ER; endoplasmic reticulum; FFAT; two phenylalanines in an acidic tract; LE; late endosome; LTP; lipid transfer protein; MCS; membrane contact site; OSBP; oxysterol-binding protein; ORP; OSBP-related protein; ORD; OSBP-rela
Keywords: 7-KC; 7 ketocholesterol; ACAT; acyl-CoA cholesterol acyl transferase; CHEH; cholesterol-5-6-epoxide hydrolase; CNS; central nervous system; CT; cholestane 3β-5α-6β triol; EC; epoxycholesterol; EGF; epidermal growth factor; ER; endoplasmic reticulum; ER
Keywords: CERT; ceramide transport protein; CPE; ceramide phosphoethanolamine; ER; endoplasmic reticulum; HDL; high density lipoprotein; LCAT; lecithin:cholesterol acyltransferase; LDL; low density lipoprotein; OSBP; oxysterol binding protein; PC; phosphatidylcholi
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons
Keywords: DIV; days in vitro; ER; endoplasmic reticulum; ERGIC; ER-Golgi intermediate compartment; E-Syt2; extended synaptotagmin2; FFAT; two phenylalanines in an acidic tract; GalT; 1,4-galactosyltransferase; ORD; OSBP-related ligand binding domain; ORP; oxyster
Cadmium induced redistribution of cholesterol by upregulating ABCA1 and downregulating OSBP
Keywords: Cadmium; Cholesterol; ABCA1; OSBP; Lysosomal acidity; Ubiquitination;
Modulation of proteolytic polyprotein processing by coxsackievirus mutants resistant to inhibitors targeting phosphatidylinositol-4-kinase IIIβ or oxysterol binding protein
Keywords: Enterovirus; PI4KB; OSBP; Polyprotein processing; Resistance mutation;
A pleckstrin homology-like domain is critical for F-actin binding and cofilin-phosphatase activity of Slingshot-1
Keywords: Slingshot; Cofilin; Pleckstrin homology (PH) domain; Actin binding; Phosphatase; Btk; Bruton's tyrosine kinase; CD; circular dichroism; CFP; cyan fluorescent protein; Itk; interleukin-2-inducible T-cell tyrosine kinase; LHK motif; Leu-His-Lys motif; OSBP;
Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307
Keywords: Enterovirus; Replication; OSBP; TTP-8307; Antiviral;
A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity
Keywords: Cholesterol efflux; High-density lipoprotein; Oxysterol-binding protein; OSBPL1A; Rare variant; ABCA1; ATP-binding cassette transporter A-1; ER; Endoplasmic reticulum; GFP; Green fluorescent protein; GST; Glutathione-S-transferase; HDL-C; High-density-lip
VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome
Keywords: AKAP; A-kinase anchor protein; ALS; Amyotrophic Lateral Sclerosis; CERT; ceramide transfer protein; ER; endoplasmic reticulum; ERAD; ER-associated destruction; FFAT; two phenylalanines in an acidic tract; MSP; major sperm protein; ORP; OSBP-related protei
The counterflow transport of sterols and PI4P
Keywords: 25-OH; 25-hydroxycholesterol; DHE; dehydroergosterol; FFAT; two phenylalanines in an acidic track; LDL; low-density lipoprotein; LTP; lipid transfer protein; MCS; membrane contact site; OSBP; oxysterol-binding protein; ORP; OSBP-related proteins; Osh; OSB
Oxysterols: From cholesterol metabolites to key mediators
Keywords: ABC; ATP-binding cassette; ACAT; acyl-coenzyme A cholesterol acyltransferase; C4; 7-hydroxycholestenone; CA; cholestanoic acid; CH25H; cholesterol-25-hydroxylase; ChEH; cholesterol epoxide hydrolase; CNS; central nervous system; CSF; cerebrospinal fluid;
OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity
Keywords: BiFC; bimolecular fluorescence complementation; ER; endoplasmic reticulum; FFAT; two phenylalanines in an acidic tract; GST; glutathione S-transferase; hyper-P; hyperphosphorylated; hypo-P; hypophosphorylated; LTP; lipid binding/transfer protein; MCS; mem
Organelle communication: Signaling crossroads between homeostasis and disease
Keywords: Organelles; Endoplasmic reticulum; Mitochondria; Calcium signaling; BNIP1; BCL2/adenovirus E1B interacting protein 1; Ca2+; calcium; CERT; ceramide transfer protein; CMT2A; Charcot-Marie-Tooth type 2A; ÎÏmt; mitochondrial transmembrane potential; Dr
NPC1, intracellular cholesterol trafficking and atherosclerosis
Keywords: NPC1; Niemann-Pick type C1; LE/LY; late endosome/lysosome; LDL; low-density lipoprotein; LDL-C; LDL-cholesterol; ER; endoplasmic reticulum; SSD; sterol-sensing domain; NTD; N-terminal domain; apoE; apolipoprotein E; LXR; liver X receptor; OSBP; oxysterolÂ
Research ArticleApolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production
Keywords: HCV; hepatitis C virus; LDs; lipid droplets; ApoJ; apolipoprotein J; ER; endoplasmic reticulum; DM; diabetes mellitus; NS; non-structural; VLDL; very-low density lipoprotein; apo; apolipoprotein; OSBP; oxysterol binding protein; CERT; ceramide-transfer pr
Oxysterol-Binding Protein Is a Phosphatidylinositol 4-Kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking
Keywords: Lipid Transfer Proteins; Phosphatidylinositol 4-Phosphate; Lipid Kinase; Viral Replication; DENV; Dengue virus; DMV; double-membrane vesicle; DRM; detergent-resistant membrane; HCV; hepatitis C virus; MβCD; methyl-β-cyclodextrin; OSBP; oxysterol-binding
Oxysterol-binding proteins: Functions in cell regulation beyond lipid metabolism
Keywords: ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinase; FFAT; two phenylalanines in an acidic tract; KC; ketocholesterol; LE; late endosome; MCS; membrane contact site; OHC; hydroxycholesterol; ORD; OSBP-related ligand-binding domain; ORP;
Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks
Keywords: ARF; ADP-ribosylation factor; DAG; diacylglycerol; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; FAPP2; Four-phosphate adaptor protein 2; FAAT motif; two phenylalanines in an acidic tract motif; GPCR; G-p
Interrelationship between ATP-binding cassette transporters and oxysterols
Keywords: ABC; ATP-binding cassette; apo; apolipoprotein; BCRP; breast cancer resistance protein; CYP; cytochrome P450; EC; epoxycholesterol; ER; endoplasmic reticulum; GS-X; glutathione-conjugate; HDL; high-density lipoprotein; INSIG; insulin-inducible genes; 7-KC
Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus
Keywords: Oxysterol-binding protein; OSBP; Salmonella enterica serovar Typhimurium; Type three secretion; SPI-2; SseL;
Intracellular sterol dynamics
Keywords: PM; plasma membrane; ER; endoplasmic reticulum; ERC; endosomal recycling compartment; LE; late endosome; LY; lysosome; LSO; LE/LY-like storage organelle; PC; phosphatidylcholine; SM; sphingomyelin; PS; phosphatidylserine; PE; phosphatidylethanolamine; DO;
Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization
Keywords: Oxysterol-binding protein-related protein 4 (ORP4); Vimentin; 25-hydroxycholesterol; Cholesterol; OSBP; Leucine repeat
Molecular mechanisms and regulation of ceramide transport
Keywords: ARF; ADP-ribosylation factor; CERT; ceramide transport protein; CGlcT; ceramide glucosyltransferase; CHO; Chinese hamster ovary; DAG; diacylglycerol; D609; tricyclodecan-9-yl xanthate; HPA-12; N-(3-hydroxyl-1-hydroxylmethyl-3-phenylpropyl)dodecanamide; ER
Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants
Keywords: DPER; dilated peripheral ER; EM; electron microscopy; ER; endoplasmic reticulum; FFAT motif; two phenylalanines in an acidic tract motif; IF; immunofluorescence; OR; OSBP-related; 25OH; 25-hydroxycholesterol; ORP; OSBP-related protein; OSBP; oxysterol bin