دانلود مقالات ISI درباره Pai-1 + ترجمه فارسی

MiR-10a and miR-181c regulate collagen type I generation in hypertrophic scars by targeting PAI-1 and uPA

Keywords: ECM; extracellular matrix; HS; hypertrophic scar; HF; hypertrophic scar-derived fibroblast; NF; normal skin-derived fibroblast; mRNA; messenger RNA; miRNA; microRNA; RT-PCR; reverse transcription polymerase chain reaction; UTR; untranslated region; uPA; u

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage

Keywords: CL-PAI-1; cleaved PAI-1; FL-PAI-1; full-length PAI-1; HNE; human neutrophil elastase; HuCASMCs; human carotid artery smooth muscle cells; LRP1; low density lipoprotein receptor-related protein 1; pAkt; phospho-Akt; PAI-1; plasminogen activator inhibitor-1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Keywords: BSA; bovine serum albumin; Enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3; ESRD; end stage renal disease; FFA; free fatty acid; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxigenase-1; MCP-1; monocyte chemoattractant protein-1; 1-MNA; 1-methylnicoti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin-6 inhibits cardiac fibroblasts differentiation into myofibroblasts via inactivation of nuclear factor κB signaling

Keywords: AAC; abdominal aortic constriction; Ang II; angiotensin II; CCK-8; Cell Counting Kit-8; CF; cardiac fibroblast; DAPI; 4′,6-diamidino-2-phenylindol; ECM; extracellular matrix; EGFP; enhanced green fluorescent protein; EMSA; electrophoretic mobility shift

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

Keywords: mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma

Keywords: HCC; hepatocellular carcinoma; HIF; hypoxia-inducible factor; k/d; knockdown; PAI-1; plasminogen activator inhibitor type 1; VEGF; vascular endothelial growth factor; cv; control virus; Plasmin; Aprotinin; Tumor hypoxia; Spheroid-embryonic body-coculture;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Dehydroepiandrosterone prevents linoleic acid-induced endothelial cell senescence by increasing autophagy

Keywords: ANOVA; one-way analysis of variance; AMPK; AMP-activated protein kinase; ATG; autophagy related genes; CVD; cardiovascular disease; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone sulfate; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric ox

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis

Keywords: TGF-β; Oxidative stress; Fibrosis; NADPH oxidases; PAI-1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleRepression of microRNA-130b by thyroid hormone enhances cell motility

Keywords: T3; thyroid hormone; TRs; thyroid hormone receptor; HCC; hepatocellular carcinoma; nTRE; negative thyroid hormone response element; ChIP; chromatin immunoprecipitation; PAI-1; plasminogen activator inhibitor-1; TRAIL; tumor necrosis factor (TNF)-related a

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy

Keywords: α-SMA; α-smooth muscle actin; COL1A1; collagen type I alpha 1; COL3A1; collagen type III alpha 1; COL6A1; collagen type VI alpha 1; DMD; Duchenne muscle dystrophy; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FBN1; fibrillin 1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

TGF-β/BMP proteins as therapeutic targets in renal fibrosis. Where have we arrived after 25 years of trials and tribulations?

Keywords: Kidney fibrosis; Smad proteins; TGF-β1; Bone morphogenetic proteins; Inhibitors; micro-RNAs; ALK1-6; activin receptor-like kinase 1-6; BAMBI; BMP and activin receptor membrane bound inhibitor; BMP; bone morphogenetic protein; CKD; chronic kidney disease;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Cylindromatosis (CYLD) inhibits Streptococcus pneumonia-induced plasminogen activator inhibitor-1 expression via interacting with TRAF-6

Keywords: Streptococcus pneumoniae; PAI-1; Cyindromatosis (CYLD); TRAF-6; Deubiquitination;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Influence of effective noninvasive positive pressure ventilation on inflammatory and cardiovascular biomarkers in stable hypercapnic COPD patients

Keywords: Noninvasive positive pressure ventilation; Chronic obstructive pulmonary disease; Cardiovascular inflammation; COPD; chronic obstructive pulmonary disease; FEV1; forced expiratory volume in 1 s; HbA1c; glycosylated hemoglobin; hs-CRP; high-sensitivity CR

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Regular ArticleResidual vein thrombosis and onset of post-thrombotic syndrome: Influence of the 4G/5G polymorphism of plasminogen activator inhibitor-1 gene

Keywords: CEAP; clinical severity, etiology, anatomy, patophysiology; DVT; deep vein thrombosis; INR; international normalized ratio; OR; odds ratio; PAI-1; plasminogen activator inhibitor-1; PTS; post-thrombotic syndrome; SD; standard deviation; t-PA; tissue-type

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Small molecule PAI-1 functional inhibitor attenuates vascular smooth muscle cell migration and survival: Implications for the therapy of vascular disease

Keywords: Vascular disease; PAI-1; SERPIN; Pericellular proteolysis; Tiplaxtinin; Vascular smooth muscle cells; Migration; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Predictive value of ankle-brachial index and PAI-1 in symptomatic intracranial atherosclerotic disease recurrence

Keywords: Intracranial stenosis; Ankle-brachial index; PAI-1; Biomarkers; Intracranial atherosclerotic disease;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1)

Keywords: Embelin; Natural product; PAI-1; Inhibitory activity; SAR study

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

A novel polymorphism in the PAI-1 gene promoter enhances gene expression. A novel pro-thrombotic risk factor?

Keywords: PAI-1; plasminogen activator inhibitor-1; SERPIN; serine protease inhibitors; t-PA; tissue-type plasminogen activator; u-PA; urokinase-type plasminogen activator; USF-1; upstream stimulatory factor-1; ATIII; antithrombin III; HPA-1; human platelet antigen

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Resistin regulates the expression of plasminogen activator inhibitor-1 in 3T3-L1 adipocytes

Keywords: PAI-1; plasminogen activator inhibitor-1; PI3K; phosphoinositide 3-kinase; PP2A; protein phosphatase 2A; GLUT4; glucose transporter type 4; ChREBP; carbohydrate responsive element-binding protein; PPARγ; peroxisome proliferator activated receptor γ; C/E

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Direct microscopic monitoring of initial and dynamic clot lysis using plasmin or rt-PA in an in vitro flow system

Keywords: FOV; filed of view; PAI-1; plasminogen activator inhibitor-1; RMS; root mean square; rt-PA; recombinant tissue plasminogen activator; Hemodynamics; Microscopy; Plasmin; Plasminogen activator; Thrombolytic therapy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Active PAI-1 as marker for venous thromboembolism: Case-control study using a comprehensive panel of PAI-1 and TAFI assays

Keywords: Fibrinolysis; PAI-1; Sensitivity and specificity; TAFI; Venous Thromboembolism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The glucagon-like peptide 1 receptor agonist enhances intrinsic peroxisome proliferator-activated receptor γ activity in endothelial cells

Keywords: GLP-1; glucagon-like peptide-1; HUVECs; human umbilical vein endothelial cells; PKA; protein kinase A; IRS-1; insulin receptor substrate-1; JNK; c-Jun N-terminal kinase; NF-κB; nuclear factor-kappa B; TNFα; tumor necrosis factor α; ICAM-1; intercellula

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr925

Keywords: Macrophage; PAI-1; FAK; Melanoma; Invasion; LRP1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Regular ArticlePlatelet-related fibrinolysis resistance in patients suffering from PV. Impact of clot retraction and isovolemic erythrocytapheresis

Keywords: ASA; aspirin; CR; clot retraction; CLT; clot lysis time; ECP; erythracytapheresis procedure; MCF; maximum clot firmness; PAI-1; plasminogen activator inhibitor-1; PV; polycythemia vera; PRP; platelet rich plasma; RBC; red blood cells; TF; tissue factor; t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Global Fibrinolytic Activity, PAI-1 Level, and 4G/5G Polymorphism in Thai Children with Arterial Ischemic Stroke

Keywords: Thrombosis; children; euglobulin clot lysis time; PAI-1; 4 G/5G polymorphism;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The influence of apolipoprotein A5 T-1131C and apolipoprotein E common genetic variants on the levels of hemostatic markers in dyslipidemic patients

Keywords: MetS; metabolic syndrome; NCEP; National Cholesterol Education Program; ATP; adult treatment panel; SBP; systolic blood pressure; DBP; diastolic blood pressure; BMI; body mass index; CRP; C-reactive protein; TC; total cholesterol; TG; triglycerides; HDLc;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Plasminogen activator inhibitor-1 4G/5G and the MTHFR 677C/T polymorphisms and susceptibility to polycystic ovary syndrome: a meta-analysis

Keywords: PCOS; PAI-1; MTHFR; Polymorphism; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Purple sweet potato color ameliorates kidney damage via inhibiting oxidative stress mediated NLRP3 inflammasome activation in high fat diet mice

Keywords: ACR; urine albumin/creatinine ratio; AGEs; advanced glycation end products; ASC; apoptosis associated speck-like protein containing a CARD; Col IV; Collagen IV; COX-2; cyclooxygenase-2; HFD; high fat diet; IL-1β; interleukin-1β; iNOS; induce nitric oxid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation

Keywords: PDGF; platelet-derived growth factor; tPA; tissue-type plasminogen activator; Tg; transgenic; KO; knock-out; uPA; urokinase plasminogen activator; ECM; extracellular matrix; PAI-1; plasminogen activator inhibitor-1; IP; intraperitoneally; CUB; complement

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Elevation of soluble form of receptor for advanced glycation end products (sRAGE) in recurrent pregnancy losses (RPL): possible participation of RAGE in RPL

Keywords: Insulin; PAI-1; recurrent pregnancy losses; resistance index of the uterine radial artery; sRAGE;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The LRP1-independent mechanism of PAI-1-inudced migration in CpG-ODN activated macrophages

Keywords: CpG-ODN; Macrophages; PAI-1; LRP1; Migration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Let-7g Improves Multiple Endothelial Functions Through Targeting Transforming Growth Factor-Beta and SIRT-1 Signaling

Keywords: endothelial function; Let-7g; PAI-1; SIRT-1; TGF-β pathwayADMA, asymmetric dimethyl arginine; EC, endothelial cell; HUVEC, human umbilical endothelial cell; IL, interleukin; MCP, monocyte chemotactic protein; miRNA, microribonucleic acid; PAI, plasminogen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity

Keywords: TGF-β1; transforming growth factor-β1; PAI-1; plasminogen activator inhibitor-1; ROS; reactive oxygen species; MEFs; mouse embryo fibroblasts; HPTEC; human proximal tubular epithelial cells; DMEM; Dulbecco's modified Eagle's Medium; DPI; diphenyleneiodo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Increase in AMPK brought about by cocoa is renoprotective in experimental diabetes mellitus by reducing NOX4/TGFβ-1 signaling

Keywords: AER; albumin excretion rate; AMPK; 5′ adenosine monophosphate-activated protein kinase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; CC; compound C; CH; cocoa enriched with polyphenols; DCF-DA; dichlorofluorescein; DM; diabetes mellitus; DN; di

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

A century old renin-angiotensin system still grows with endless possibilities: AT1 receptor signaling cascades in cardiovascular physiopathology

Keywords: RAS; renin-angiotensin system; AOG; angiotensinogen; Ang II; angiotensin II; ACE; angiotensin converting enzyme; ARBs; angiotensin AT1 receptor blockers; Mas R; Mas receptor; TGF-β; transforming growth factor-β; Ang A; angiotensin A; eNOS; endothelial

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Guía de práctica clínica de la ESC sobre diabetes, prediabetes y enfermedad cardiovascular, en colaboración con la European Association for the Study of Diabetes

Keywords: Guías de Práctica Clínica; Diabetes mellitus; Enfermedad cardiovascular; Intolerancia a la glucosa; Manejo del paciente; Prevención; Epidemiología; Pronóstico; Diagnóstico; Factores de riesgo; Tratamiento farmacológico; Intervenciones coronarias;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH

Keywords: Apo; apolipoprotein; BMI; body mass index; CV; coefficient of variation; CVD; cardiovascular disease; ELISA; enzyme-linked immunosorbant assay; F1 + 2; protrombin fragment 1 + 2; FH; familial hypercholesterolaemia; LDL; low density lipoprotein; PAI-1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

Keywords: TGF-β; NOX; NADPH oxidases; PAI-1; ROS; p53; EGFR; SMADs;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Coagulofibrinolytic changes in patients with disseminated intravascular coagulation associated with post-cardiac arrest syndrome― Fibrinolytic shutdown and insufficient activation of fibrinolysis lead to organ dysfunction

Keywords: PCAS; post-cardiac arrest syndrome; ROSC; return of spontaneous circulation; DIC; disseminated intravascular coagulation; MODS; multiple organ dysfunction syndrome; EXDP; fibrin degradation product by neutrophil elastase; TAFI; thrombin-activatable fibrin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

TM5275 prolongs secreted tissue plasminogen activator retention and enhances fibrinolysis on vascular endothelial cells

Keywords: tPA; tissue plasminogen activator; PAI-1; plasminogen activator inhibitor-1; VEC; vascular endothelial cell; TIRF; total internal reflection fluorescence; HBS; HEPES-buffered solution; CLSM; confocal laser scanning microscope; fibrinolysis; plasminogen ac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Investigating the anti-mineralocorticoid properties of synthetic progestins used in hormone therapy

Keywords: Prog; progesterone; MR; mineralocorticoid receptor; HRT; hormone replacement therapy; MPA; medroxyprogesterone acetate; NET; norethisterone; NET-A; norethisterone acetate; NET-EN; norethisterone enanthate; Ald; aldosterone; MRE/GRE; mineralocorticoid/gluc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Obesity and IL-6 interact in modulating the response to endotoxemia in mice

Keywords: ALT; Alanine Aminotransferase; DIO; diet-induced obesity; Gal; galectin; IFN; interferon; IL; interleukin; LPS; lipopolysaccharide; PAI-1; plasminogen activator inhibitor-1; SAA; serum amyloid A; TNF; tumor necrosis factor; Inflammation; Cytokines; Endoto

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Association for Academic SurgerySubstance P is an early mediator of peritoneal fibrinolytic pathway genes and promotes intra-abdominal adhesion formation

Keywords: Intra-abdominal adhesion; Substance P; Neurokinin-1 receptor; tPA; PAI-1; HIF-1α; HIF-2α; VEGF-A;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Rosuvastatin reduced deep vein thrombosis in ApoE gene deleted mice with hyperlipidemia through non-lipid lowering effects

Keywords: VT; venous thrombosis; IVC; inferior vena cava; TW; thrombus weight; PAI-1; plasminogen activator inhibitor-1; IL-6; interleukin-6; VTE; venous thromboembolism; DVT; deep vein thrombosis; PE; pulmonary embolism; JUPITER; justification for the use of stati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Buckwheat trypsin inhibitor enters Hep G2 cells by clathrin-dependent endocytosis

Keywords: rBTI; recombinant buckwheat trypsin inhibitor; Tf; transferrin; DAPI; 2-(4-amidinophenyl)-1H-indole-6-carboxamidine; MDC; monodansylcadaverine; FITC; fluorescein isothiocyanate; DMSO; dimethyl sulfoxide; Noc; nocodazole; HEPES; (4-(2-hydroxyethyl)-1-piper

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients

Keywords: Adjuvant chemotherapy; Node-negative breast cancer; uPA; PAI-1; Prognostic factors; Cancer biomarker;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Ectopic fat and cardiometabolic and vascular risk

Keywords: VAT; visceral adipose tissue; SAT; subcutaneous adipose tissue; T2DM; type 2 diabetes mellitus; USPIO; ultrasmall super-paramagnetic iron oxide; CAD; coronary artery disease; CRP; C-reactive protein; PAI-1; plasminogen activator inhibitor-1; CT; computed

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Genetics of chronic rhinosinusitis: State of the field and directions forward

Keywords: Genetics; genome; variation; chronic rhinosinusitis; nasal polyposis; single nucleotide polymorphism; polymorphism; candidate gene; linkage; genome wide association study; susceptibility; sinusitis; AERD; Aspirin-exacerbated respiratory disease; AF; Allel

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2013 سفارش ترجمه

Hypercoagulability Markers Predict Thrombosis in Single Ventricle Neonates Undergoing Cardiac Surgery

Keywords: 21; ATIII; antithrombin III; CI; confidence interval; CPB; cardiopulmonary bypass; FVIII; factor VIII; ICU; intensive care unit; LOS; length of stay; PAI-1; plasminogen activator inhibitor; PC; protein C; PPP; platelet poor plasma; PS; protein S; RFU; rel

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Human C-reactive protein accentuates macrophage activity in biobreeding diabetic rats

Keywords: C-reactive protein; NF-κB; Macrophages; Tissue factor; PAI-1; PKC; p47Phox

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه