PAMPs, PRRs and the genomics of gram negative bacterial recognition in fish
Keywords: Innate immunity; Bacteria; PRR; PAMP; Microarray
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Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands
Keywords: IPA; Ingenuity Pathway Analysis; LPS; lipopolysaccharide; PAMP; pathogen-associated molecular pattern; PRR; pattern recognition receptors; RNAi; RNA interference; TLR; Toll-like receptor; Innate immunity; Gene expression; RNA interference; Lipopolysacchar
Characterization and expression studies of Gaduscidin-1 and Gaduscidin-2; paralogous antimicrobial peptide-like transcripts from Atlantic cod (Gadus morhua)
Keywords: 0 h; individuals that were collected prior to injection; AMP; antimicrobial peptide; ANOVA; analysis of variance; ASAL; formalin-killed, atypical Aeromonas salmonicida; BLAST; basic local alignment search tool; cDNA; complimentary DNA; GAD; gaduscidin; CG
Making sense of regulatory T cell suppressive function
Keywords: APC; antigen presenting cells; BM; bone marrow; BMT; bone-marrow transplantation; cAMP; cyclic AMP; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DN; double negative Treg cells; EAE; experimental autoimmune e
Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant
Keywords: PAMP; Pathogen-associated molecular pattern; Poly I:C; polyinosinic:polycytidylic acid; GVHD; graft-versus-host disease; HCT; hematopoietic cell transplant; RVI; respiratory viral infection; LB; lymphocytic bronchiolitis; BO; bronchiolitis obliterans; LPS
Individual sequence variability and functional activities of fibrinogen-related proteins (FREPs) in the Mediterranean mussel (Mytilus galloprovincialis) suggest ancient and complex immune recognition models in invertebrates
Keywords: PAMP; pathogen-associated molecular patterns; MBL; mannose-binding lectin; MASPs; MBL-associated serine proteases; MAC; membrane attack complex; EST; expressed sequence tag; LTA; lipoteichoic acid; FREP; fibrinogen-related protein; ORF; open reading frame
Biochemical and phylogenetic analysis of CEBiP-like LysM domain-containing extracellular proteins in higher plants
Keywords: CEBiP; Chitooligosaccharide; GPI; LYM; LysM; Medicago truncatula; @ATPase; anti-P-type H+-ATPase antiserum; @biotin; anti-biotin antiserum; @LYM1; anti-MtLYM1 antiserum; @LYM2; anti-MtLYM2 antiserum; CEBiP; chitin elicitor-binding protein; EGS; ethylene g
MAp19, the alternative splice product of the MASP2 gene
Keywords: MBL; mannan-binding lectin; MASP; MBL-associated serine protease; MAp; MBL-associated protein; pAb; polyclonal antibody; MBS; m-maleimidobenzoyl-N-hydroxysuccinimid; DVS; divinylsulfone; PPD; purified protein derivative; HRP; horseradish peroxidase; KLH;
CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS
Keywords: TLR4; CD14; TRIF; MyD88; LPS; PAMP; DAMP; MHC I; Phagocytosis
A systems biology perspective on plant-microbe interactions: Biochemical and structural targets of pathogen effectors
Keywords: AIS; artificial immune system; AVR; AViRulence; DAMP; danger-associated molecular pattern; DOR; dense overlapping regulon; EDV; effector detector vector; ETI; effector-triggered immunity; ETS; effector-triggered susceptibility; FFN; feed-forward network (
Functional immune response in Pecten maximus: Combined effects of a pathogen-associated molecular pattern and PAH exposure
Keywords: Pecten maximus; Scallop; Immune function; Phagocytosis; Lipopolysaccharide; PAMP; Polycyclic aromatic hydrocarbon; Phenanthrene
Molecular cloning and functional characterization of a mouse gene upregulated by lipopolysaccharide treatment reveals alternative splicing
Keywords: FBS; fetal bovine serum; FCM; flow cytometry; GNB; Gram-negative bacterium; LBP; LPS binding protein; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MLrg; mouse lipopolysaccharide-responding gene; MLrgW; MLrg wild-type; MLrgS; MLrg splic
Differential expression of toll-like receptor mRNA in selected tissues of goat (Capra hircus)
Keywords: TLR, toll-like receptor; PRR, pattern recognition receptor; PAMP, pathogen-associated molecular pattern; RT-PCR, reverse transcriptase-polymerase chain reactionTLR; Expression profile; PAMP; PRR; Innate immunity; RT-PCR; Sequencing
The multifunctional leucine-rich repeat receptor kinase BAK1 is implicated in Arabidopsis development and immunity
Keywords: Receptor kinase; Plant development; Plant immunity; Arabidopsis; BAK1; PEPR1; Effector protein; PAMP
Research ArticleThe scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells
Keywords: DC; dendritic cell; MÏ; macrophage; PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; ACAMP; apoptotic cell-associated molecular pattern; SR; scavenger receptor; CLR; C-type lectin receptor; TLR; Toll-like receptor; RIG; ret
CD14 but not MD2 transmit signals from DAMP
Keywords: PAMP; DAMP; TLR; CD14; LPS; MD2
Plant Immunity Triggered by Microbial Molecular Signatures
Keywords: Disease resistance; plant–microbe interactions; signal transduction; PAMP; innate immunity; receptor
Oncolytic viruses as experimental treatments for malignant gliomas: Using a scourge to treat a devil
Keywords: AdV; Adenovirus; APC; antigen-presenting cell; BBB; blood-brain barrier; CED; convection-enhanced delivery; CNS; central nervous system; ECM; extracellular matrix; FasL; Fas ligand; GALV; gibbon ape leukemia virus; GBM; glioblastoma mulitforme; GIM; gli
Partial role of TLR4 as a receptor responding to damage-associated molecular pattern
Keywords: NC, necrotic cells; DAMP, damage-associated molecular pattern; PAMP, pathogen-associated molecular patternToll-like receptor; Necrotic cells; Dendritic cells; NF-κB; Inflammation; DAMP; PAMP
NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish
Keywords: BIR; baculovirus inhibitor of apoptosis protein repeat; CARD; caspase recruitment domain; CIITA; class IImajor histocompatibility complex, transactivator; HET-E; bacterial nucleotide triphosphatase protein; IPAF; ice protease-activating factor; LRR; leuci
ReviewTreatment failure in hepatitis C: Mechanisms of non-response
Keywords: AA; African-American; CA; Caucasian-American; HCV; hepatitis C virus; ISG; interferon-stimulated gene; PAMP; pathogen-associated molecular pattern; RVR; rapid virologic response; SVR; sustained virologic response; Hepatitis C; Interferon; Treatment; Race;
Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors
Keywords: AD; Alzheimer 's disease; ADDL; amyloid-β derived diffusible ligand; APP; amyloid-β precursor protein; BBB; blood-brain barrier; CNS; central nervous system; CSF; cerebrospinal fluid; DAMP; danger-associated molecular pattern; FPR; N-formyl peptide re
Postnatal Sepsis, Necrotizing Entercolitis, and the Critical Role of Systemic Inflammation in White Matter Injury in Premature Infants
Keywords: CONS; Coagulase-negative staphylococcus (CONS); LPS; Lipopolysaccharide; MRI; Magnetic resonance imaging; NEC; Necrotizing enterocolitis; PAMP; Pathogen-associated molecular pattern; pre-OL; Premyelinating oligodendrocyte; PVL; Periventricular leukomalaci
Flagellin as a good carrier and potent adjuvant for Th1 response: Study of mice immune response to the p27 (Rv2108) Mycobacterium tuberculosis antigen
Keywords: MT p27; PAMP; Flagellin; Immune response; Adjuvant
Effect of concurrent intratracheal lipopolysaccharide and human serum albumin challenge on primary and secondary antibody responses in poultry
Keywords: Airborne; Chicken; Human serum albumin; Immune response; LPS; PAMP
Differential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: Implications for understanding the “switch” to opiate addiction
Keywords: post-translational processing; opiates; endorphin; TRH; hypothalamus; drug addiction; AHiAL; anterolateral nucleus of the amygdala; ATF-1; activation transcription factor-1; CRE; cyclic AMP-response element; CREM; cAMP response element modulator; CRH; cor
Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization
Keywords: CD8 T cell; immunologic memory; innate immunity; allergy; TH1/TH2; dendritic cell; IL-12; BAL; Bronchoalveolar lavage; CD8 Tm; CD8 memory T cell; DC; Dendritic cell; NK; Natural killer; PAMP; Pathogen-associated molecular pattern; SEB; Staphylococcal ente
Innate microbial sensors and their relevance to allergy
Keywords: Innate; immunity; receptor; microbial recognition; Toll-like receptor; PAMP; PRR; CLR; NOD-like receptor; antimicrobial peptide; allergy; asthma; hygiene hypothesisAD, Atopic dermatitis; APC, Antigen-presenting cell; CLR, C-type lectin receptor; CRP, C-re
Receptor mosaics of neural and immune communication: Possible implications for basal ganglia functions
Keywords: Ab; amyloid-beta protein; ABGA; antibasal ganglia antibody; AD; Alzheimer's disease; AGE; advanced glycation endproducts; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; CA; cornu ammonis; CB; cannabinoid; CD; cluster designa
Physiopathologie du choc septique
Keywords: Sepsis; SIRS; PAMP; PRR; NF-κB; cytokine; TNF; apoptose; endothélium; dysoxie tissulaire; système nerveux autonome; axe hypothalamo-hypophyso-surrénalien; polymorphisme génétique; Sepsis; SIRS; PAMP; PRR; NF-κB; cytokine; TNF; apoptosis; endotheliu
New perspectives on mannan-binding lectin-mediated complement activation
Keywords: C3 convertase; Lectin pathway; MBL; Complement bypass pathway; AP; alternative pathway; CP; classical pathway; CRD; carbohydrate-recognition domain; FBG; fibrinogen-like domain; IGFBP-5; insulin-like growth factor-binding protein 5; LP; lectin pathway; MA
How bacteria and their products provide clues to vaccine and adjuvant development
Keywords: Adjuvant; PAMP; TLR pathway; Lipopolysaccharide; CpG
Analysis of ESTs from Lutzomyia longipalpis sand flies and their contribution toward understanding the insect-parasite relationship
Keywords: GALE; galectin; AMP; antimicrobial peptide; GNBP; gram-negative binding protein; PAMP; pathogen-associated molecular pattern; PGRP; peptidoglycan recognition proteins; PRR; pattern recognition receptor; TEP; thioester-containing protein family; SCR; scave
Intricacies of Host Response in Acute Pancreatitis
Keywords: ACAMP; apoptotic cell-associated molecular pattern; CCK; cholecystokinin; HSP; heat shock protein; ICAM; intercellular adhesion molecule; IL; interleukin; NF-κB; nuclear factor κB; PAMP; pathogen-associated molecular pattern; RIP; receptor interacting p
Strategies for targeting T-cells in allergic diseases and asthma
Keywords: AHR; airway hyperreactivity; AP; activator protein; APC; antigen-presenting cell; BAL; bronchoalveolar lavage; cAMP; cyclic adenosine monophosphate; CBP; CREB-binding protein; CpG DNA; CpG-containing immunostimulatory deoxyribonucleic acid; CsA; cyclospor
IL-17 production by thymocytes upon CD3 stimulation and costimulation with microbial factors
Keywords: Thymocytes; Interleukin-17; Cytokines; PAMP; Autoimmunity; T cell; Inflammation
Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides
Keywords: Proadrenomedullin; PAMP; MrgX2; Hypotension; Adrenal chromaffin cells; DRG; GPCR;
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
Keywords: Atopic eczema; asthma; allergic rhinoconjunctivitis; IgE; CARD4; NOD1; SNP; haplotype; association; CARD; Caspase recruitment domain-containing protein; KORA; Cooperative Health Research in the Region of Augsburg; NOD; Nucleotide-binding oligomerization
Effect of adrenomedullin and proadrenomedullin N-terminal 20 peptide on sugar transport in the rat intestine
Keywords: Jejunum; PAMP; Adrenomedullin; SGLT1; Alpha-methylglucoside (MG); cAMP;
Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation
Keywords: MDP; Chitosan; Adjuvant synergy; PAMP; NOD; TLR
Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
Keywords: Drosophila melanogaster; Innate immunity; JNK signaling; aop; anterior open; dSR-CI; Drosophila scavenger receptor CI; GNBP; Gram-negative bacteria-binding protein; hep; hemipterous; Imd; immune defiency; kay; kayak; MAPK; mitogen-activated protein kinase
Candida albicans double-stranded DNA can participate in the host defense against disseminated candidiasis
Keywords: Candida albicans infection; Candida albicans DNA; Macrophages; Cytokines; CFU; colony-forming units; CQ; chloroquine; CT DNA; calf thymus DNA; dsDNA; double-stranded DNA; IFN; interferon; IL; interleukin; i.p.; intraperitoneally; ODN; oligodeoxynucleotide
Sex steroids, APOE genotype and the innate immune system
Keywords: Aβ; amyloid beta peptide; AD; Alzheimer's disease; APOE; apolipoprotein E; APOE TR; apolipoprotein E targeted replacement; APP; amyloid precursor protein; AR; androgen receptor; c-fms; colony stimulating factor receptor gene; CSF; colony stimulating fact
Links between the innate immune system and sleep
Keywords: Sleep; infection; innate immunity; virus; bacteria; toll-like receptors; cytokines; circadian rhythms; stress; asthma; APR; Acute-phase response; dsRNA; Double-stranded RNA; EEG; Electroencephalographic; GHRH; Growth hormone-releasing hormone; NK cells;
Gene-inducing program of human dendritic cells in response to BCG cell-wall skeleton (CWS), which reflects adjuvancy required for tumor immunotherapy
Keywords: ADA; adenosine deaminase; ANOVA; analysis of variance; AP-1; activating protein-1; BCG-CWS; bacillus Calmette-Guérin cell-wall skeleton; BIGM103; BCG-induced gene in monocyte, clone 103; CCL; chemokine (C-C motif) ligand; CD; cluster of differentiation;
Characterization of adrenomedullin in birds
Keywords: Adrenomedullin; PAMP; Gallus; Hypoxia; Glucocorticoid; Synteny;
Neurochemical brain groups activated after an isotonic blood volume expansion in rats
Keywords: Fos-oxytocin immunoreactivity; Fos-vasopressin immunoreactivity; Fos-serotonin immunoreactivity; Fos-tyrosine hydroxylase immunoreactivity; central cardiovascular pathways; ANP; atrial natriuretic peptide; AP; area postrema; AVP; vasopressin; BNST; bed nu
The role of suppressors of cytokine signalling in thymopoiesis and T cell activation
Keywords: SOCS; suppressor of cytokine signalling; CIS; cytokine-induced SH2-containing protein; SH2; src-homology 2; JAK; Janus kinase; STAT; signal transducers and activators of transcription; IL; interleukin; IFN; interferon; SCF; stem cell factor; SP; single po
Comparative genetics and innate immune functions of collagenous lectins in animals
Keywords: APP; Actinobacillus pleuropneumoniae; CG; conglutinin; CL-43; collectin-43; CL-46; collectin-46; CL-L1; collectin liver 1; CL-P1; collectin placenta 1; CRD; carbohydrate-recognition domain; FCN; ficolin; GlcNAc; N-acetyl-d-glucosamine; MASP; MBL-associate