Keywords: سنتز موازی; Parallel synthesis; Polymer library; Non-viral vector; Degradable cationic polymers; Low charge density; Gene delivery;
مقالات ISI سنتز موازی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: سنتز موازی; UKJDZGMKCIFXFI-FVALVINRSA-N; BGEKALKTMWNTQD-RFIQQHCTSA-N; CQIMLMYPHBOQSL-RFIQQHCTSA-N; IRAOESAINDQEIG-UUOLGLRASA-N; VAKQHCQRJMYBJV-YAZVLAJYSA-N; FNRQKKGAOVAEOI-ABUSLMHJSA-N; DAVUQBKACMLZJU-IGXOHMADSA-N; GGLYYGLRTMUIDR-YMIIJLGTSA-N; OPIFYJPCQJSGJM-KFQSXEOQ
Keywords: سنتز موازی; Glycine receptor; Allosteric potentiator; Pain; Parallel synthesis; Pharmacophore-based virtual screen;
Keywords: سنتز موازی; Thiazole; Parallel synthesis; Amyloid reducing agent; Alzheimer’s disease
Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process
Keywords: سنتز موازی; Antiplatelet therapy; ADP; P2Y12 antagonists; HTS; Parallel synthesis;
Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators
Keywords: سنتز موازی; mGlu5 receptor; Negative allosteric modulator; 4-amino-3-arylsulfonyl-quinolines; Parallel synthesis; Optimization;
Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors
Keywords: سنتز موازی; Sphingosine 1-phosphate lyase; Hit-to-lead; Inhibitor; Parallel synthesis; Structure-based design
Efficient access to sp3-rich tricyclic amine scaffolds through Diels-Alder reactions of azide-containing silyloxydienes
Keywords: سنتز موازی; Parallel synthesis; Diels-Alder cycloaddition; Polycyclic heterocycles; PTSA; para-toluenesulfonic acid; NP; natural product; Fsp3; fraction sp3; HBD; hydrogen bond donors; HBA; hydrogen bond acceptors; tPSA; topological polar surface area; rotB; rotata
Rapid development of two factor IXa inhibitors from hit to lead
Keywords: سنتز موازی; Factor IXa; Hit-to-lead; Structure based drug design; Parallel synthesis; Anticoagulant
Development of two novel Eu2+-activated phosphors in the Na-Sc-Si-O system and their photoluminescence properties
Keywords: سنتز موازی; Na3ScSi3O9; NaScSi2O6; Solution method; Parallel synthesis;
Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors
Keywords: سنتز موازی; Hepatitis C virus; NS5B polymerase; Antiviral; Non-nucleoside inhibitor; Structure based drug design; Parallel synthesis;
Antimalarial and cytotoxic activities of chiral triamines
Keywords: سنتز موازی; Chiral amines; Antimalrial; Malaria; Solid-phase organic synthesis; Libraries; Mixtures based libraries; Parallel synthesis
Microwave-mediated synthesis and manipulation of a 2-substituted-5-aminooxazole-4-carbonitrile library
Keywords: سنتز موازی; Microwave-assisted synthesis; Oxazoles; Parallel synthesis; Flow chemistry;
Synthesis of a 1,3,5-benzotriazepine-2,4-dione based library
Keywords: سنتز موازی; Microwaves; Parallel synthesis; Heterocycles; Amides; Cyclisation;
Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway
Keywords: سنتز موازی; PI3-Kinase inhibitors; Pharmacological tools; Aminothiazoles; Parallel synthesis; Isoform selectivity;
Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins
Keywords: سنتز موازی; Sirtuin; Parallel synthesis; Chemical tool; Metabolism; Neurodegenerative diseases;
An efficient one-pot synthesis of 3-aryl-5-methylisoxazoles from aryl aldehydes
Keywords: سنتز موازی; One-pot synthesis; Isoxazoles; Parallel synthesis; Library synthesis; 1,3-Dipolar cycloaddition;
Synthesis and solid state study of pyridine- and pyrimidine-based fragment libraries
Keywords: سنتز موازی; Heterocycles; Microwaves; Parallel synthesis; Piperazines; Flow chemistry;
Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors
Keywords: سنتز موازی; Hypoxia-inducible factor-1α; Quinazolin-4-ones; Parallel synthesis;
Pregnenolone derivatives as potential anticancer agents
Keywords: سنتز موازی; Pyrazoline; Pregnenolone; Parallel synthesis; Benzylidene; MDA-MB-231; HepG2 cell lines
Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity
Keywords: سنتز موازی; Parallel synthesis; Microwaves; Benzodiazepines; Trypanosoma;
A simple subatmospheric pressure device to drive reagents through microchannels for solution-phase synthesis in a parallel fashion
Keywords: سنتز موازی; Parallel synthesis; Subatmospheric pressure; Microreactor; Solution-phase synthesis; Suzuki coupling
On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity
Keywords: سنتز موازی; Solid-phase synthesis; Gramicidin-S; Gramicidin analogs; Antimicrobial; Combinatorial chemistry; Parallel synthesis
Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs
Keywords: سنتز موازی; mGluR5; Negative allosteric modulator; Parallel synthesis;
Parallel synthesis and anti-inflammatory activity of cyclic peptides cyclosquamosin D and Met-cherimolacyclopeptide B and their analogs
Keywords: سنتز موازی; Parallel synthesis; Solid phase synthesis; Natural cyclopeptides; Anti-inflammatory activity
Discovery and optimization of N-acyl and N-aroylpyrazolines as B-Raf kinase inhibitors
Keywords: سنتز موازی; B-Raf inhibitor; Pyrazoline; Parallel synthesis
Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonists
Keywords: سنتز موازی; Corticotropin-releasing factor; Depression; Anxiety; Parallel synthesis;
Discovery and structure-guided drug design of inhibitors of 11β-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold
Keywords: سنتز موازی; 11β-Hydroxysteroid-dehydrogenase type I inhibitors; Spiro-carboxamide; Structure-guided drug design; Hit-to-Lead process; Parallel synthesis
Discovery and optimization of a novel Neuromedin B receptor antagonist
Keywords: سنتز موازی; NMBR; Antagonist; Parallel synthesis; Ary-hexahydro-dibenzodiazepin-1-one;
Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis
Keywords: سنتز موازی; CB2; Agonist; Lipophilicity; LiPE; Parallel synthesis;
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization
Keywords: سنتز موازی; Histone deacetylases; Parallel synthesis
Parallel synthesis of potent dopaminergic N-phenyltriazole carboxamides applying a novel click chemistry based phenol linker
Keywords: سنتز موازی; Dopamine receptor; D3; Click chemistry; Parallel synthesis; Catch and release; Triazole
Solution-phase parallel synthesis of substituted chalcones and their antiparasitary activity against Giardia lamblia
Keywords: سنتز موازی; Parallel synthesis; Chalcones; Giardia lamblia; Antiparasitary
Three-component one-pot synthetic route to 2-amino-5-alkylidene-thiazol-4-ones
Keywords: سنتز موازی; 2-Amino-5-alkylidene-thiazol-4-one; Rhodanine; Knoevenagel condensation; Multi-component reaction; Parallel synthesis; Microwave-assisted organic synthesis;
Novel and potent small-molecule urotensin II receptor agonists
Keywords: سنتز موازی; Urotensin II; Agonists; SAR; R-SAT; Parallel synthesis
Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-κB
Keywords: سنتز موازی; Resveratrol analogues; Parallel synthesis; Cyclooxygenase; Inhibition; NF-κB
Parallel synthesis, molecular modelling and further structure–activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors
Keywords: سنتز موازی; Acylthiocarbamates; HIV-1; Non-nucleoside reverse transcriptase inhibitors; Parallel synthesis
N-Acylated and N,N′-diacylated imidazolidine-2-thione derivatives and N,N′-diacylated tetrahydropyrimidine-2(1H)-thione analogues: Synthesis and antiproliferative activity
Keywords: سنتز موازی; Acylthioureas; Antiproliferative activity; Parallel synthesis
Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors
Keywords: سنتز موازی; O-(2-Phthalimidoethyl)-N-arylthiocarbamates; HIV-1; Non-nucleoside reverse transcriptase inhibitors; Parallel synthesis; Molecular docking
Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)
Keywords: سنتز موازی; Solid-phase library; Hit to lead; Combinatorial chemistry; Non-additive SAR; Non-linear SAR; Growth hormone secretagogue receptor; GHSR; G-protein coupled receptor; GPCR; Solid-phase synthesis; Parallel synthesis; GPCR agonist; Matrix library
Synthesis of a natural product-inspired eight-membered ring lactam library via ring-closing metathesis
Keywords: سنتز موازی; Eight-membered; Natural product; Lactam; Library; Ring-closing metathesis; Medium-ring; Octalactin; Parallel synthesis
2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: Optimization via array synthesis
Keywords: سنتز موازی; CETP; HDL; Parallel synthesis; Benzoxazole; Cholesteryl ester transfer protein; CETP inhibitor; Coronary heart disease; CHD; SAR
Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity
Keywords: سنتز موازی; Anti-parasitic; Anti-protozoan; Neglected diseases; Tropical diseases; Compound library; Parallel synthesis; Whole-cell assays
Substrate specificity and screening of the integral membrane protease Pla
Keywords: سنتز موازی; Yersinia pestis; Plasminogen activator; Protease substrate; Peptide inhibitor; Positional scan; Parallel synthesis;
Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands
Keywords: سنتز موازی; Cannabinoid CB2 receptor; Parallel synthesis; Sulfamoyl benzamides; Structure–activity relationship; Antiallodynic activity
Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides
Keywords: سنتز موازی; Nitroderivatives; Antileishmanial agents; Parallel synthesis; SAR
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure–activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate
Keywords: سنتز موازی; Thiocarbamates; HIV-1; Non-nucleoside reverse transcriptase inhibitors; Parallel synthesis
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure–activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates
Keywords: سنتز موازی; Thiocarbamates; HIV-1; Non-nucleoside reverse transcriptase inhibitors; Parallel synthesis
Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists
Keywords: سنتز موازی; Progesterone; Receptor; Antagonist; oxa-Steroid; Glucocorticoid; Parallel synthesis; SAR study; In vitro; In vivo
Parallel synthesis of individual shikimic acid-like molecules using a mixture-operation strategy and ring-closing enyne metathesis
Keywords: سنتز موازی; Shikimic acid; Carbocycle; Ring-closing enyne metathesis; Stereochemistry; Parallel synthesis;