Early growth response-2 expression in uterine leiomyoma cells: regulation and function
Keywords: Collagen; c-myc; dermatopontin; Egr-2; leiomyomata; PCNA; TGF-β3;
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Microglia activation during neuroregeneration in the adult vertebrate brain
Keywords: TH; tyrosine hydroxylase; IBA1; ionized calcium binding adaptor molecule 1; MAC2; Galectin-3/Mac-2; PCNA; proliferating cell nuclear antigen; Neurogenesis; Regeneration; Salamander; Newt; Dopamine; Microglia;
Nitric oxide counteracts the hyperoxia-induced proliferation and proinflammatory responses of mouse astrocytes
Keywords: ACM; astrocyte conditioned medium; ApoE; apolipoprotein E; ApoJ/clusterin; apolipoprotein J; CNS; central nervous system; GFAP; glial fibrillary acidic protein; PCNA; proliferating cell nuclear antigen; PGE2; prostaglandin E2; Nitric oxide; Oxygen; Astroc
Anti-proliferative actions of 2-decylamino-5,8-dimethoxy-1,4-naphthoquinone in vascular smooth muscle cells
Keywords: 2-decylamino-DMNQ; 2-decylamino-5,8-dimethoxy-1,4-naphthoquinone; VSMCs; vascular smooth muscle cells; PDGF; platelet-derived growth factor; Erk1/2; extracellular regulated kinases 1/2; PLCγ; phospholipase γ; PDGF-Rβ; PDGF receptor β; CDK; cyclin-depe
Dynamic regulation of PCNA ubiquitylation/deubiquitylation
Keywords: Ubiquitylation; Deubiquitylation; PCNA; USP1; ELG1;
Effects of benzo(a)pyrene on the skeletal development of Sebastiscus marmoratus embryos and the molecular mechanism involved
Keywords: BaP; Craniofacial skeleton; Developmental defects; Shh; PCNA; Sebastiscus marmoratus;
Daily treatment with α-naphthoflavone enhances follicular growth and ovulation rate in the rat
Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon nuclear translocator; αNF; α-naphthoflavone; eCG; equine chorionic gonadotrophin; hCG; human chorionic gonadotrophin; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; DMBA; dimethylbenz[a]anthracene; BaP;
Diffusion-Weighted Imaging Is Superior to Positron Emission Tomography in the Detection and Nodal Assessment of Lung Cancers
Keywords: 10; ADC; apparent diffusion coefficient; DWI; diffusion-weighted magnetic resonance imaging; 18F-FDG; 18-fluoro-2-deoxy-glucose; FN; false-negative; FP; false-positive; GGO; ground glass opacity; PCNA; proliferating cell nuclear antigen; PET-CT; positron
Ubiquitin-family modifications in the replication of DNA damage
Keywords: DNA polymerase; PCNA; UV light;
Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain
Keywords: Cyclin E; cdk2; Central nervous system; Postmitotic neuron; Cell cycle; Cerebral cortex; Cerebellum; Cortical neuron; Purkinje cell; Proliferation; PCNA; Mouse;
Anticancer activity of a low immunogenic protein toxin (BMP1) from Indian toad (Bufo melanostictus, Schneider) skin extract
Keywords: Common Indian toad; Bufo melanostictus; BMP1; Anti-proliferative; Apoptogenic; CDK; Low immunogenic protein; AO; acridine orange; BMP1; Bufo melanostictus protein 1; CDKI; cyclin-dependent kinase inhibitor; DAPI; 4â²,6-diamidino-2-phenylindole; EAC; Ehrl
Dietary intake of 17α-ethinylestradiol promotes leukocytes infiltration in the gonad of the hermaphrodite gilthead seabream
Keywords: EDCs; endocrine disrupting chemicals; EE2; 17α-ethinylestradiol; AG; acidophilic granulocytes; E2; 17β-estradiol; Mc; macrophages; Ly; lymphocytes; ERs; estrogen receptors; GSI; gonadosomatic index; MG; gonad mass; MB; body mass; T; testosterone; 11KT;
A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
Keywords: PCNA; Sulfolobus tokodaii; Heterotetramer; Holliday junction clamp; Crystal structure;
Dietary acrylamide does not increase colon aberrant crypt foci formation in male F344 rats
Keywords: Aberrant crypt foci; Acrylamide; Azoxymethane; Colon carcinogenesis; Dietary fat; PCNA;
Neutralization of Tumor Necrosis Factor Bioactivity Ameliorates Urethane-Induced Pulmonary Oncogenesis in Mice
Keywords: BAL; bronchoalveolar lavage; CBA; cytometric bead array; COPD; chronic obstructive pulmonary disease; F8A; factor VIII-associated protein; IFN; interferon; IL; interleukin; LLC; Lewis lung carcinoma; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxy
Roles of sequential ubiquitination of PCNA in DNA-damage tolerance
Keywords: DNA repair; DNA-damage tolerance; PCNA; Ubiquitination; TLS;
Ub-family modifications at the replication fork: Regulating PCNA-interacting components
Keywords: PCNA; Ubiquitin; SUMO; DNA replication; DNA repair;
IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest
Keywords: APC; adenomatous polyposis coli; DMSO; dimethyl sulphoxide; GFP; green fluorescent protein; GSK-3β; glycogen synthase kinase-3β; IQGAP1; IQ-domain GTPase activating protein 1; PCNA; proliferating cell nuclear antigen; RNA Polymerase II; RNA Pol II; RPA;
PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance
Keywords: PCNA; Polη; Somatic hypermutation; Translesion synthesis; DNA damage tolerance; Ubiquitination;
Different roles of p53 in the regulation of DNA damage caused by 1,2-heteroannelated anthraquinones and doxorubicin
Keywords: DXR; doxorubicin; DNMT; DNA methyltransferase; HDAC1; histone deacetylase 1; NCI 60; National Cancer Institute 60; NSC number; the NCI's internal ID number; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FACS; fluorescence activated ce
Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: Evidence for inhibition of activated MAPKs/NF-κB and reduced cell proliferation
Keywords: BrdU; bromodeoxyuridine; CNT; cumulative number of tumors; DAS; diallyl sulfide; DMBA; 7, 12-dimethylbenz[a]anthracene; ERK; extracellular signal regulates kinase; PFE; pomegranate fruit extract; H2O2; hydrogen peroxide; IHC; immunohistochemical; JNK; c-J
Characterization of Vascular Injury Responses to Stent Insertion in an Ex-vivo Arterial Perfusion Model
Keywords: ACH; acetylcholine; bDNA; branched DNA; BMS; bare metal stent; BrDU; bromodeoxyuridine; CTGF; connective tissue growth factor; DAPI; diamidino-2-phenylindole; DES; drug-eluting stent; EC; endothelial cell; eNOS; endothelial nitric oxide synthase; MMP2; ma
Glucocorticoids dexamethasone and hydrocortisone inhibit proliferation and accelerate maturation of chicken cerebellar granule neurons
Keywords: AraC; Cytosine arabinoside; BrdU; Bromodeoxyuridine; CCGN; Chicken cerebellar granule cell; DAB; Diaminobenzidine; Dex; Dexamethasone; DIV; Days in vitro; EGL; External granular layer; GC; Glucocorticoid; HC; Hydrocortisone/cortisol; IGL; Internal granula
Activating transcription factor 3 (ATF3) promotes sublytic C5b-9-induced glomerular mesangial cells apoptosis through up-regulation of Gadd45α and KLF6 gene expression
Keywords: MsPGN; mesangioproliferative glomerulonephritis; GMCs; glomerular mesangial cells; ECM; extracellular matrix; Thy-1N; Thy-1 nephritis; ATS; anti-thymocyte serum; HIS; heat-inactivated serum; ATF3; activating transcription factor 3; Gadd45α; growth arrest
Cigarette smoking, cyclooxygenase-2 pathway and cancer
Keywords: AA; arachidonic acid; PLA2; phospholipase A2; COX; cyclooxygenase; PGE2; prostaglandin E2; TxA2; thromboxane A2; TxB2; thromboxane B2; PGI2; prostacyclin; PGES; prostaglandin E synthase; TxAS; thromboxane synthase; PGIS; prostacyclin synthase; GPCR; G-pro
Increased circulating leptin level inhibits folliculogenesis in vespertilionid bat, Scotophilus heathii
Keywords: Leptin; Leptin-receptor; Insulin; LH-receptor; LH; Insulin receptor; Bat; Ovary; Apoptosis; Caspase-3; PCNA; PARP;
Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis
Keywords: CNPase; 2â²,3â²-Cyclic Nucleotide 3â²-Phosphodiesterase; dpi; days post MOG immunization; EAE; Experimental Autoimmune Encephalomyelitis; GFAP; Glial Fibrillary Acidic Protein; GRP; glial restricted progenitor; GST-Ï; glutathione S-transferase isoform
ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation
Keywords: Akt; protein kinase B; CAT; catalase; CDKs; cyclin-dependent kinases; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinase; FASN; fatty acid synthase; FFAs; free fatty acids; H2DCFDA; 2â²,7â²-dichlorofluorescin diacetate; JNK; c-Jun NH2
Selected primary and secondary metabolites in fresh persimmon (Diospyros kaki Thunb.): A review of analytical methods and current knowledge of fruit composition and health benefits
Keywords: VIG; Volatile Independent Group; PCNA; Pollination Constant Non Astringent; VDG; Volatile Dependent Group; PCA; Pollination Constant Astringent; PVA; Pollination Variant Astringent; PVNA; Pollination Variant Non Astringent; FW; Fresh Weight; GC; Gaschroma
Annexin A2 Mediates Up-regulation of NF-κB, β-catenin, and Stem Cell in Response to Progastrin in Mice and HEK-293 Cells
Keywords: CD44; DCAMKL+1; Colorectal Cancer; Signaling; AnxA2; annexin A2; ANXA2+/+ mice; wild-type C57Bl/J6 mice; ANXA2â/â mice; C57Bl/J6 mice knocked down for the expression of annexin A2; CCK1R and CCK2R; cholecystokinin type 1 and type 2 receptors, respecti
Acycloguanosyl 5â²-thymidyltriphosphate, a Thymidine Analogue Prodrug Activated by Telomerase, Reduces Pancreatic Tumor Growth in Mice
Keywords: Suicide Gene Therapy; Human Telomerase Reverse Transcriptase; hTERT; Telomere; ACV; acyclovir; ACV-TP-dA; acycloguanosyl 2â²-deoxy-5â²-adenosyltriphosphate; ACV-TP-dC; acycloguanosyl 5â²-cythydyltriphosphate; ACV-TP-dG; acycloguanosyl 2â²-deoxy-5â²-g
The Physiological Significance of p27KIP1 Expression in Detrusor Function
Keywords: urinary bladder; urinary bladder neck obstruction; cyclin-dependent kinase inhibitor p27; hyperplasia; mice; BOO; bladder outlet obstruction; CDK; cyclin-dependent kinase; CKI; CDK inhibitor; DLPP; detrusor leak point pressure; NFAT; nuclear factor of act
Phenotypic and genomic analysis of an exceptional case of enteropathy associated T-cell lymphoma
Keywords: CD; coeliac disease; CGH; comparative genomic hybridisation; CNV; copy number variants; EATL; enteropathy associated T-cell lymphoma; EMA; endomysial antibodies; FACS; flowcytometry; GFD; gluten free diet; IEL; intraepithelial lymphocytes; LPL; lamina pro
HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death
Keywords: AP-1; activator protein 1; APC; anaphase promoting complex; ATL; adult T-cell leukemia; ATM kinase; ataxia telangiectasia mutated kinase; BES; base excision repair; Chk1; checkpoint kinase 1; Chk2; checkpoint kinase 2; CREB; cyclic AMP response element-bi
Pathologic Assessment of Radiofrequency Ablation of Pulmonary Metastases
Keywords: NADH; reduced nicotinamide adenine dinucleotide; PCNA; proliferative cell nuclear antigen; RF; radiofrequency;
Streamlined, automated protocols for the production of milligram quantities of untagged recombinant human cyclophilin-A (hCypA) and untagged human proliferating cell nuclear antigen (hPCNA) using ÃKTAxpressâ¢
Keywords: Cyclophilin-A; PCNA; Automated protein purification; Liquid chromatography; ÃKTAXpressâ¢;
Comparative proteomic analysis of anti-benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-transformed and normal human bronchial epithelial G0/G1 cells
Keywords: Anti-benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (anti-BPDE); Anti-BPDE-transformed cells; Two-dimensional gel electrophoresis; Q-TOF MS/MS; PCNA; TPD52;
Bone Morphogenetic Protein Signaling Regulates Gastric Epithelial Cell Development and Proliferation in Mice
Keywords: Trefoil Factor 2; TFF2; Transforming Growth Factor α; TGF; BMP; bone morphogenetic protein; ERK; extracellular signal-regulated kinase; GSII; Griffonia (Bandeiraea) simplicifolia lectin II; IF; intrinsic factor; PCNA; proliferating cell nuclear antigen;
Roles of Werner syndrome protein in protection of genome integrity
Keywords: γ-H2AX; phosphorylated histone H2AX; 4-NQO; 4-nitroquinoline 1-oxide; 5-OHdC; 5-hydroxycytidine; 5-OHU; 5-hydroxyuracil; 8-oxodA; 8-oxoadenine; 8-oxodG; 8-oxoguanine; ALT; alternative lengthening of telomeres; APE1; apurinic/apyrimidinic endonuclease 1;
Patterns of cell proliferation and rod photoreceptor differentiation in shark retinas
Keywords: AC; amacrine cells; BP; bipolar cells; ce; ciliary epithelium; CMZ; ciliary marginal zone; GCL; ganglion cell layer; HC; horizontal cells; INL; inner nuclear layer; INLi; inner part of the INL; INLo; outer part of the INL; IPL; inner plexiform layer; L; l
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors α and β/δ (but not γ) and liver X receptor activators
Keywords: Atopic dermatitis; barrier function; liver X receptor; mouse model; peroxisome proliferator-activated receptor α, β/δ, and γ; TH2 cells; AD; Atopic dermatitis; CRTH; Chemoattractant receptor-homologous molecule expressed on TH2; LXR; Liver X recep
ERK1/2-Dependent Vascular Endothelial Growth Factor Signaling Sustains Cyst Growth in Polycystin-2 Defective Mice
Keywords: ADPKD; autosomal dominant polycystic kidney disease; CC3; cleaved caspase-3; DMOG; 2-oxoglutarate analogues dimethyloxaloylglycine; ERK; extracellular signal-regulated kinase; HIF; hypoxia-inducible factor; MEK; mitogen signal-regulated kinase; PC1; pol
Regulation of DNA repair by parkin
Keywords: Parkinson disease; Parkin; DNA excision repair; PCNA;
Cellular proliferation in complicated versus uncomplicated atherosclerotic lesions: Total cell population, foam cells and newly formed microvessels
Keywords: Atheroclerosis; Cellular proliferation; PCNA; Carotid plaques; Foam cells; Neovascularization;
Platelet-derived growth factor expression correlates with tumor grade and proliferative activity in human oligodendrogliomas
Keywords: ABC; avidin-biotin complex; bFGF; basic fibroblast growth factor; DAB; 3,3-diaminobenzidine tetrahydrochloride; EGF; epidermal growth factor; H&E; hematoxylin and eosin; IGF-1; insulinlike growth factor 1; LI; labeling index; NGF; nerve growth factor; PCN
New insights into the relationship of neurogenesis and affect: tickling induces hippocampal cell proliferation in rats emitting appetitive 50-kHz ultrasonic vocalizations
Keywords: neurogenesis; individuality; tickling; depression; ultrasonic vocalization; USV; BrdU; 5-bromo-2â²-deoxyuridine; HCP; hippocampal cell proliferation; PBS; phosphate-buffered saline; PCNA; proliferating-cells-nuclear-antigen; 5-HT; serotonin;
Carbamylated darbepoetin derivative prevents endothelial progenitor cell damage with no effect on angiogenesis
Keywords: EPCs; endothelial progenitor cells; EPO; erythropoietin; CKD; chronic kidney disease; rHuEPO; recombinant human erythropoietin; darbe; darbepoetin; C-darbe; carbamylated darbepoetin; TNBSA; trinitrobenzenesulfonic acid; PCNA; proliferating cell nuclear an
Vascular endothelial cells and smooth muscle cells mediate carbachol-induced hepatocyte proliferation via muscarinic receptors and IP3/PKC signaling cascades
Keywords: Neural obesity; Obese; Vagus nerve; Cell growth; CIHP; carbachol-induced hepatocyte proliferation; Co(HH); coculture with HH; Co(SM-3); coculture with SM-3; HNPC; hepatic nonparenchymal cell; PCNA; proliferating cell nuclear antigen; VEC; vascular endothe
Saccharomyces boulardii Inhibits EGF Receptor Signaling and Intestinal Tumor Growth in Apcmin Mice
Keywords: EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; IGF-1R; insulin-like growth factor-1 receptor; MAP; mitogen-activated protein; PCNA; proliferating cell nuclear antigen; PKC; protein kinase C; Sb; Saccharomyces boulardii
Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice
Keywords: Pten KO; Pten-deficient; EPA; eicosapentaenoic acid; ROS; reactive oxygen species; HCC; hepatocellular carcinoma; NASH; non-alcoholic steatohepatitis; NAFLD; non-alcoholic fatty liver disease; TG; triglyceride; PUFA; polyunsaturated fatty acid; SREBP-1; s