دانلود مقالات ISI درباره Pde + ترجمه فارسی

New findings from the first transcriptome of the Bothrops moojeni snake venom gland

Keywords: Bothrops moojeni; Transcriptomics; Snake venom; cysteine-rich secretory protein; Hyaluronidase; Three-finger toxin; NGS; Next Generation Sequencing; RIN; RNA Integrity Number; SRA; Sequence Read Archive; TSA; Transcriptome Shotgun Assembly; NCBI; National

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

MC1R signaling. Intracellular partners and pathophysiological implications

Keywords: AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; ARRB; β-arrestin; ASIP; agouti signal protein; CBD103; dog β-defensin-3; CREB; cAMP responsive-element binding protein; EDN1; endothelin 1; ER; endoplasmic reticulum; ERK; extracellular signal-reg

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2017 سفارش ترجمه

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease

Keywords: 5-HT; 5-hydroxytryptamine; 7,8-DHF; 7,8-dihydroxyflavone; ACh; acetylcholine; AD; adenosine; ADL; activities of daily living; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; 5′AMP-activated protein kinase; BDNF; brain-derived neurotro

دانلود رایگان متن کامل مقاله ISI 91 صفحه سال انتشار : 2017 سفارش ترجمه

Converting high order linear PDEs to first order

Keywords: Polynomial matrix; PDE; Exact sequence;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Original articleInvestigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteers: A 31P MRS study

Keywords: ATP; Fructose infusion; Oral challenge; NAFLD; Liver; 31P MRS; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; ATP; adenosine triphosphate; MRS; magnetic resonance spectroscopy; Pi; inorganic phosphate; PDE; phosphodiesters;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Phagocytosis of bone marrow derived macrophages is controlled by phosphoinositide 3-kinase γ

Keywords: BMDM; bone marrow derived macrophages; PI3Kγ; phosphoinositide 3-kinase gamma; PAMP; pathogen associated molecular pattern; DAMP; damage associated molecular patterns; PKA; protein kinase A; PDE; phosphodiesterase; KO; knock out; KD; kinase dead; PI3Kγ;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase

Keywords: AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; CaMK; Ca2 +/calmodulin-dependent protein kinase; ERK; extracellular-regulated kinase; HSL; hormone-sensitive lipase; PDE; phosphodiesterase; PKA; protein kinase A; PKB; protein kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Nitrosopersulfide (SSNO−) targets the Keap-1/Nrf2 redox system

Keywords: Hmox1; heme oxygenase-1; Keap-1; Kelch-like ECH-associated protein; SSNO−; nitrosopersulfide; Nrf2; nuclear factor (erythroid-derived 2)-like 2; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; NO and H2S cross talk; Nitroxyl; Nitrosopersulfide;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors

Keywords: PDE; phosphodiesterase; TNF-α; tumour necrosis factor; nm; nanomolar; IL; interleukin; μM; micromolar; @; at; PBMC; peripheral blood mononuclear cells; LPS; lipopolysaccharides; COPD; chronic obstructive pulmonary disease; CC; column chromatography; HCl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment

Keywords: PDE4D inhibitors; cAMP enhancers; Memory behavior test; Pharmacokinetic analyses; Molecular dynamics simulation; In silico ADMET properties; AD; Alzheimer Disease; cAMP; cyclic adenosine monophosphate; CR3; conserved region 3; CREB; cAMP response element-

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Comprehensive analysis of chemokine-induced cAMP-inhibitory responses using a real-time luminescent biosensor

Keywords: AC; adenylate cyclase; APC; allophycocyanin; AUC; area under curve; CHK; chemokine; EPAC; exchange protein directly activated by cAMP; FSK; forskolin; HEKgloCX3CR1; HEK293 clone stably expressing CX3CR1 and the GloSensor™ F-22; PDE; phosphodiesterase; P

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Ca2 +/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function

Keywords: Heart; Sinoatrial node pacemaker cells; Phosphodiesterase Type 1A; Calcium; cAMP; AC; adenylyl cyclase; AKAP; A-kinase-anchoring protein; AP; action potential; CaM; calmodulin; CaMKII; calmodulin-dependent protein kinase II; Cav-3; caveolin-3; FRET; fluor

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics

Keywords: AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; AKAP; A-kinase anchor protein; AMP; 5′ adenosine monophosphate; AMPK; AMP-activated protein kinase; Arfgap1; ADP-ribosylation factor GTPase-activating protein 1; Arhgef2; Rho guanine nucleotide ex

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

A mesh adaptivity scheme on the Landau-de Gennes functional minimization case in 3D, and its driving efficiency

Keywords: 3D mesh adaptivity; Metrics; Finite elements; Nematic liquid crystals; PDE; Nonlinear analysis;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Rainfall induced groundwater mound in wedge-shaped promontories: The Strack-Chernyshov model revisited

Keywords: Dirichlet conditions for Poisson equation; Analytic and numeric solutions; Dupuit-Forchheimer model; Water table with natural recharge; Evaporation and sea water intrusion; BVP; Boundary value problem; PDE; Partial differential equation; PK-77; Polubari

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Epidermal growth factor receptor inhibitor cancer drug gefitinib modulates cell growth and differentiation of acute myeloid leukemia cells via histamine receptors

Keywords: 4-MH; 4-methylhistamine; AML; acute myelogenous leukemia; CML; chronic myelogenous leukemia; cAMP; cyclic adenosine monophosphate; CRE; cAMP response element; EGFR; epidermal growth factor receptor; ER; estrogen receptor alpha; FSK; Forskolin; GPCR; G-pro

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Modeling of dislocations in a CDW junction: Interference of the CDW and normal carriers

Keywords: CDW; Vortex; Dislocation; Junction; PDE; Comsol

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of human skin mast cell histamine release by PDE inhibitors

Keywords: Mast cell; Histamine; PDE;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells

Keywords: Resveratrol; Bone marrow mesenchymal stem cells (BM-MSCs); Neuronal differentiation; Sirtuin1 (SIRT1); AMPK; AMP-activated protein kinase; BHA; butylated hydroxyanisole; BM-MSCs; bone marrow-mesenchymal stem cells; cAMP; cyclic AMP; ctrl-MSCs; control-MSC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Oral Phenylephrine HCl for Nasal Congestion in Seasonal Allergic Rhinitis: A Randomized, Open-label, Placebo-controlled Study

Keywords: Seasonal allergic rhinitis; Phenylephrine HCl; Nasal congestion; Dose-ranging trial; Oral decongestant; AE; adverse event; AR; allergic rhinitis; BP; blood pressure; EE; efficacy evaluable; FDA; Food and Drug Administration; HR; heart rate; ITT; intent-to

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Granulocyte-colony stimulating factor activates JAK2/PI3K/PDE3B pathway to inhibit corticosterone synthesis in a neonatal hypoxic-ischemic brain injury rat model

Keywords: Hypoxia-ischemia; Granulocyte colony stimulating factor; Y1; Corticosterone; JAK2; PDE; Cholera toxin; Adrenal cortical cells; Hypothalamic-pituitary-adrenal axis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

A Double-Blind Placebo-Controlled Study of the Effects of Olprinone, a Specific Phosphodiesterase III Inhibitor, for Preventing Postoperative Atrial Fibrillation in Patients Undergoing Pulmonary Resection for Lung Cancer

Keywords: AF; atrial fibrillation; AMP; adenosine monophosphate; BNP; B-type natriuretic peptide; CRP; C-reactive protein; LV; left ventricular; PDE; phosphodiesterase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Weighted curvature-preserving PDE image filtering method

Keywords: Image filtering; Curvature-preserving; PDE; Structure tensor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors

Keywords: AD; Alzheimer disease; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; cGMP; cyclic guanosine monophosphate; OLT; object location test; ORT; object recognition test; PDE; phosphodiesterase; PDE4Is; PDE4 inhibitors; PTC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of β2-adrenergic receptor by (R,R′)-4′-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells

Keywords: AC; adenylate cyclase; α-MSH; α-melanocyte stimulating hormone; ANOVA; analysis of variance; AR; adrenergic receptor; ATR; ataxia telangiectasia and Rad3-related protein; BCA; bicinchoninic acid; cAMP; cyclic adenosine monophosphate; CI; cell index; CIM

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphodiesterase inhibitor, pentoxifylline enhances anticancer activity of histone deacetylase inhibitor, MS-275 in human breast cancer in vitro and in vivo

Keywords: HDAC; MS-275; PDE; Pentoxifylline; Apoptosis; Xenograft

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Herbs to curb cyclic nucleotide phosphodiesterase and their potential role in Alzheimer's disease

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; AD; Alzheimer's disease; PDE; phosphodiesterases; Aβ; amyloid beta; NFTs; neurofibrillary tangles; FAD; familial Alzheimer's disease; SAD; sporadic Alzheimer's disease; APP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

PDE and cognitive processing: Beyond the memory domain

Keywords: cAMP; cGMP; PDE; Attention; Gating; Response inhibition;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Bivariate spline solution of time dependent nonlinear PDE for a population density over irregular domains

Keywords: Bivariate splines; Numerical solution; PDE; Allee effect; Ecology; Epidemiology50-030; 70-060; 70-140

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Temporal and organ-specific detection of cNMPs including cUMP in the zebrafish

Keywords: Cyclic CMP; Cyclic UMP; Zebrafish; cAMP; adenosine 3′,5′-cyclic monophosphate; cCMP; cytidine 3′,5′-cyclic monophosphate; cGMP; guanosine 3′,5′-cyclic monophosphate; cIMP; inosine 3′,5′-cyclic monophosphate; cNMP; nucleoside 3′,5′-cycl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer

Keywords: ABTS; 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); AML; acute myeloid leukemia; ApnA; diadenosine polyphosphates; ATP; adenosine-5′-triphosphate; ATX; autotaxin; BALF; bronchoalveolar lavage fluid; bis-pNPP; bis(p-nitrophenyl) phosphate; BLM

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review

Keywords: Anthelmintics; Benzimidazole; Heterocyclic ring systems; Pharmacological activities; SAR study; NPY; neuropeptide; CYP450; cytochrome P450; HBV; hepatitis B virus; HCV; hepatitis C virus; RSV; respiratory syncytial virus; VV; varicella virus; BVDV; bovine

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

An adaptive octree finite element method for PDEs posed on surfaces

Keywords: Surface; PDE; Finite elements; Traces; Unfitted grid; Octree grid

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatum

Keywords: Basal ganglia; Schizophrenia; Parkinson's disease; Huntington's disease; ANOVA; Analysis of Variance; BAC; bacterial artificial chromosome; c-Fos(+); c-Fos immunopositive nuclei; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effect of cilostazol against doxorubicin-induced cardiomyopathy in mice

Keywords: AMPK; AMP-activated protein kinase; BNP; B-type natriuretic peptide; Cilo; cilostazol; CTGF; connective tissue growth factor; DIC; Dox-induced cardiomyopathy; Dox; doxorubicin; HMGB1; high-mobility group box 1; HO-1; heme oxygenase 1; LVEDD; left ventricl

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells

Keywords: AC; adenylyl cyclases; AKAR; A-kinase activity receptor 3; AP; action potential; β-AR; β-adrenergic receptor; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; ISO; isoproterenol; M; membrane; PDE; phosphodiesterase; PKA; protein kinase A; PLB; pho

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Proof of concept for a banding scheme to support risk assessments related to multi-product biologics manufacturing

Keywords: Biologics; Manufacturing; Cross-contamination; Cleaning validation; Impurities; Risk assessment; ADE; acceptable daily exposure; API; active pharmaceutical ingredient; FDA; Food and Drug Administration; G-CSF; granulocyte colony stimulating factor; GM-CSF

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2015 سفارش ترجمه

Exponential speed of uniform convergence of the cell density toward equilibrium for subcritical mass in a Patlak-Keller-Segel model

Keywords: Chemotaxis; Patlak-Keller-Segel; PDE; Parabolic-elliptic system; Speed of convergence; Gradient flow;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2015 سفارش ترجمه

Soluble adenylyl cyclase accounts for high basal cCMP and cUMP concentrations in HEK293 and B103 cells

Keywords: cAMP; adenosine 3′,5′-cyclic monophosphate; cGMP; guanosine 3′,5′-cyclic monophosphate; cCMP; cytidine 3′,5′-cyclic monophosphate; cNMP; 3′,5′-cyclic nucleoside monophosphate; cUMP; uridine 3′,5′-cyclic monophosphate; pGC; particulate

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of recombinant human antiquitin in E. coli: Partial enzyme activity in selected ALDH7A1 missense mutations associated with pyridoxine-dependent epilepsy

Keywords: AASA; α-aminoadipic semialdehyde; ATQ; antiquitin; HGMD; Human Genome Mutation Database; IPTG; isoproplythiogalactoside; P6C; Δ1-piperideine-6-carboxlylate; PDB; Protein Data Base; PDE; pyridoxine dependent epilepsy; PLP; pyridoxal phosphate; SDS-PAGE;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

PDE7A1 hydrolyzes cCMP

Keywords: A549; human lung carcinoma cell line; AMP; adenosine 5′-monophosphate; cAMP; adenosine 3′,5′-cyclic monophosphate; B103; rat neuroblastoma cells; CMP; cytidine 5′-monophosphate; cCMP; cytidine 3′,5′-cyclic monophosphate; CyaA; Bordetella pertu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator

Keywords: c-di-GMP; cyclic dimeric guanosine monophosphate; DGC; diguanylate cyclase; GTP; guanosine triphosphate; MorA; motility regulator A; PDB; protein data bank; PDE; phosphodiesterase; pGpG; phosphate guanosine phosphate guanosine; Motility regulator A; Digua

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleNon-alcoholic fatty liver disease: Spectral patterns observed from an in vivo phosphorus magnetic resonance spectroscopy study

Keywords: NAFLD; non-alcoholic fatty liver disease; 31P-MRS; phosphorus magnetic resonance spectroscopy; NASH; non-alcoholic steatohepatitis; PME; phosphomonoesters; PE; phosphoethanolamine; PDE; phosphodiesters; GPC; glycerophosphocholine; NTP; nucleotide triphosp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Infinity Laplacian on graphs with gradient terms for image and data clustering

Keywords: Weighted graphs; PdE; Laplacian; Unsupervised; Classification; Segmentation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Iso-level tool path planning for free-form surfaces

Keywords: Iso-level tool path; Globally optimal; PDE; Iso-scallop; Smooth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling

Keywords: 5-HT; 5-hydroxytryptamine; AKAP; A-kinase anchoring protein; DMSO; dimethyl sulfoxide; GRK; G protein-coupled receptor kinase; HEK293; human embryonic kidney cell line; IBMX; isobutylmethylxanthine; IP; immunoprecipitation; PDE; phosphodiesterase; PKA; pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in can

Keywords: luteolin; 3′,4′,5,7-tetrahydroxyflavone; IFN; interferon; JAK; Janus kinase; STAT; signal transducer and activator of transcription; ISRE; interferon α-stimulated response element; PDE; phosphodiesterase; cAMP; cyclic adenosine 3′,5′-monophosphat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding

Keywords: aPKC; atypical protein kinase C; cAMP; cyclic AMP-dependent protein kinase; LC3; microtubule-associated protein 1A/B light chain 3; MEK; mitogen-activated protein kinase kinase/ERK kinase; MEKK; MEK kinase; NBR; neighbour of BRCA1 gene 1 protein; NF-κB;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphodiesterase from Daboia russelli russelli venom: Purification, partial characterization and inhibition of platelet aggregation

Keywords: Phosphodiesterase; Daboia russelli russelli; Snake venom; Platelet aggregation; Enzyme inhibition; ADP; adenosine diphosphate; AMP; adenosine monophosphate; ATP; adenosine triphosphate; AVS; anti-venom serum; BCIP; 5-bromo-4-chloro-3′-indolyphosphate; b

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A soluble phosphodiesterase in Leishmania donovani negatively regulates cAMP signaling by inhibiting protein kinase A through a two way process involving catalytic as well as non-catalytic sites

Keywords: L. donovani; Phosphodiesterase; Psudosubstrate residues; Phosphorylation; Protein kinase A; PDE; phosphodiesterase; DAPI; 4′,6-diamidino-2′-phenylindole dihydrochloride; LdPDEA; L. donovani cAMP phosphodiesterase A; LdPDED; L. donovani cAMP phosphodie

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه