دانلود مقالات ISI درباره Pde + ترجمه فارسی

Crosstalk between Mycobacterium tuberculosis and the host cell

Keywords: AC; adenylyl cyclase; AKAP7; A-kinase anchor protein 7 isoform gamma; AM; alveolar macrophage; ATP; adenosine triphosphate; BCG; Bacille Calmette-Guérin; cAMP; cyclic adenosine monophosphate; CD1; cluster of differentiation 1; c-di-AMP; cyclic-di-adeno

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice

Keywords: ACSF; artificial cerebrospinal fluid; cAMP; cyclic adenosine monophosphate; DA; dopamine; DARPP-32; DA- and cAMP regulated phosphoprotein of 32 kDa; D1R; D1 receptor; A1R; A1 receptor; eIPSCs; evoked IPSCs; sIPSCs; spontaneous IPSCs; IEI; inter-event int

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: Evidence from clinic to laboratory

Keywords: Sal-B; salvianolatic acid B; VASP; vasodilator-stimulated phosphoprotein; AFM; atomic force microscopy; PDE; phosphodiesterase; IBMX; 3-isobutyl-1-methylxanthine; cAMP; 3,5-cyclic adenosine monophosphate; aspirin; acetylsalicylic acid; PRP; platelet-rich

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer

Keywords: cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; CaP; prostate cancer; CRPC; castration-resistant prostate cancer; PDE; phosphodiesterase; GEO; Gene Expression Omnibus; Rolipram; Forskolin; AR; cAMP/PKA pathways; CaP metastasis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Sex differences in SR Ca2 + release in murine ventricular myocytes are regulated by the cAMP/PKA pathway

Keywords: cAMP; cyclic adenosine monophosphate; DMSO; dimethyl sulfoxide; EC; excitation-contraction; Fura-2 AM; fura-2 acetoxymethyl; FR; fractional release; GAPDH; Glyceraldehyde 3-phosphate dehydrogenase; IV; current-voltage; PCR; polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Lack of Efficacy of an Inhibitor of PDE4 in Phase 1 and 2 Trials of Patients With Nonalcoholic Steatohepatitis

Keywords: Fatty Liver Disease; Therapeutic Targets; Treatment; PDE4; AE; adverse event; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under the plasma drug concentration time curve; AUCtau; area under the plasma drug concentration time c

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Systems biology of synaptic plasticity: A review on N-methyl-d-aspartate receptor mediated biochemical pathways and related mathematical models

Keywords: AC; adenylyl cyclase; AKAP; A-kinase anchoring protein; AMPAR; A-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor; CaM; calmodulin; CaMKII; Ca2+/CaM-dependent protein kinase II; cAMP; cyclic adenosine monophosphate; HFS; high frequency stimula

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Eucommia ulmoides Oliv.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine

Keywords: AChE; acetylcholinesterase; AD; Alzheimer's disease; AIDS; acquired immunodeficiency syndrome; Ang II; angiotensin II; AST; aspartate transaminase; BAT-SNA; Brown adipose tissue sympathetic nerve activity; cAMP; cyclic adenosine monophosphate; CJ-S (131);

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

The structural basis of action of vanadyl (VO2+) chelates in cells

Keywords: acac; acetylacetonate, as in bis(acetylacetonato)oxidovanadium(IV) or VO(acac)2; alx; allixin; ASP; acylation-stimulating protein; CHO; Chinese hamster ovary; ENDOR; electron nuclear double resonance; EGFR; epidermal growth factor receptor; EPR; electron

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: Therapeutic perspectives

Keywords: Heart; MAPK; Cardiac diseases; Mitochondria; Cell signaling; AngII; angiotensin II; CA; constitutively active; CHIP; C terminus of Hsc70-interacting protein; CT-1; cardiotrophin-1; ΔΨmit; mitochondrial membrane potential; DN; dominant negative; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2014 سفارش ترجمه

Preliminary investigation of the use of newborn dried blood spots for screening pyridoxine-dependent epilepsy by LC-MS/MS

Keywords: PDE; Pyridoxine-dependent epilepsy; α-AASA; α-Aminoadipic semialdehyde antiquitin; DBS; Dried blood spots; NBS; Newborn screening; P6C; Piperideine-6-carboxylate; Pyridoxine-dependent epilepsy (PDE); α-Aminoadipic semialdehyde (α-AASA); Piperideine-6-

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Case studyEarly diagnosis of pyridoxine-dependent epilepsy: Video-EEG monitoring and biochemical and genetic investigation

Keywords: Pyridoxine; Seizure; PDE; ALDH7A1; Antiquitin; Mutation; EEG;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Targetting cancer with Ru(III/II)-phosphodiesterase inhibitor adducts: A novel approach in the treatment of cancer

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; LDH; lactate dehydrogenase; PDE; cyclic nucleotide phosphodiesterases; PDEi; cyclic nucleotide phosphodiesterases inhibitors; Ru; ruthenium; NO; nitric oxide;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes

Keywords: AE; anion exchanger; AMPK; AMP-activated protein kinase; CA; carbonic anhydrase; CTS; cardiotonic steroids; DAB; 1,4-dideoxy-1,4-imino-d-arabinitol; DIDS; 4,4′-diisothiocyanostilbene-2,2′-disulfonic acid; EGFR; epidermal growth factor receptor; ERK; e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca2 + stores and inhibition of capacitative calcium entry

Keywords: cAMP; adenosine 3′,5′-cyclic monophosphate; [Ca2 +]c; cytoplasmic Ca2 + concentration; PDE; phosphodiesterase; KBS; Krebs bicarbonate solution; db-cAMP; dibutyryl cyclic AMP; FFA; flufenamic acid; SERCA; sarcoplasmic/endoplasmic reticulum Ca2 + ATP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)

Keywords: ELISA; enzyme-linked immunosorbent assay; qRT-PCR; quantitative real-time reverse-transcription polymerase chain reaction; ER; estrogen receptor; SERM; selective estrogen receptor modulator; cAMP; cyclic adenosine monophosphate; ALP; alkaline phosphatase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Ginseng-Aconite Decoction elicits a positive inotropic effect via the reverse mode Na+/Ca2+ exchanger in beating rabbit atria

Keywords: GAD; Ginseng-Aconite Decoction; β-AR; β-adrenoceptor; LTCC; L-type Ca2+ channel; PKA; protein kinase A; NCX; Na+/Ca2+ exchanger; PDE; phosphodiesterase; propranolol; a β-adrenoceptor blocker; diltiazem; an L-type Ca2+ channel inhibitor; KB-R7943; a N

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Potent suppression of c-di-GMP synthesis via I-site allosteric inhibition of diguanylate cyclases with 2′-F-c-di-GMP

Keywords: C-di-GMP; 2′-H-c-di-GMP; 2′-F-c-di-GMP; 2′-OMe-c-di-GMP; Polymorphism; G-quadruplex; DOSY; DGC; PDE; PilZ;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Total synthesis of PDE-I and -II by copper-mediated double aryl amination

Keywords: Amination; Cascade reaction; Copper; One-pot reaction; PDE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle

Keywords: cAMP; cyclic adenosine 3′, 5′-monophosphate; PKA; cAMP-dependent protein kinase; IK; delayed rectifier potassium current; Epac; exchange proteins directly activated by cAMP; GEF; guanine nucleotide exchange factors; ICa; L-type calcium current; PDE; p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

CaV1.2 signaling complexes in the heart

Keywords: LTCC; L-type Ca2 + channel; βAR; β-adrenergic receptor; EPR; E type prostaglandin receptor; RyR2; type 2 ryanodine receptor; AC; adenylyl cyclase; PDE; phosphodiesterase; PP; protein phosphatase; AKAP; A kinase anchoring protein; PKA; protein kinase A;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Botany, traditional uses, phytochemistry and pharmacology of Waltheria indica L. (syn. Waltheria americana): A review

Keywords: WCSP; World Checklist of Selected Plant Families; GRIN; Germplasm Ressources Information Network; US; United States; NO; Nitric oxide; TNF; Tumor necrosis factor; IL; Interleukin; LPS; Lipopolysaccharide; IFN; Interferon; DMSO; Dimethylsulphoxide; MTT; 1-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

cAMP/PKA signaling defects in tumors: Genetics and tissue-specific pluripotential cell-derived lesions in human and mouse

Keywords: BAH; bilateral adrenal hyperplasia; MMAD/AIMAH; massive macronodular adrenocortical disease/ACTH-independent adrenocortical hyperplasia; ACC; adrenal cortical carcinoma; ACA; adrenal cortical adenoma; ACT; adrenal cortical tumor; PRKAR1A; regulatory subun

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Numerical study of CO2 enhanced natural gas recovery and sequestration in shale gas reservoirs

Keywords: Numerical simulation; Shale gas reservoir; CSEGR; Dual-porosity; Knudsen diffusion; Ordinary diffusion; CBM; coal bed methane; CCS; carbon dioxide capture and storage; CSEGR; CO2 sequestration with enhanced natural gas recovery; DGM; dusty gas model; ECBM

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

A Prospective Longitudinal Survey of Erectile Dysfunction in Patients with Localized Prostate Cancer Treated with Permanent Prostate Brachytherapy

Keywords: prostate; prostatic neoplasms; erectile dysfunction; brachytherapy; questionnairesEBRT, external beam radiotherapy; ED, erectile dysfunction; EF, erectile function; IIEF, International Index of EF; OS, overall satisfaction; PB, prostate brachytherapy; PDE

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G

Keywords: AGS; activator of G protein-signaling; cAMP; cyclic adenosine monophosphate; CTD; carboxy-terminal domain; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; Epac; exchange protein activated by cAMP; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibitors of Bacillus anthracis edema factor

Keywords: Adenylyl cyclase; Calmodulin; Edema factor; Fluorescence spectroscopy; (M)ANT-nucleotides; Molecular modeling; ANT; anthraniloyl; AC; adenylyl cyclase; ACD; adenylyl cyclase domain; EF; edema factor AC toxin from Bacillus anthracis; CaM; calmodulin; FRET;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

A parallel coupling strategy for the Chimera and domain decomposition methods in computational mechanics

Keywords: Domain decomposition method; Chimera method; Non-conforming mesh; Parallelization; Finite element methods; PDE

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of human antiquitin in E. coli: Enzymatic characterization of twelve ALDH7A1 missense mutations associated with pyridoxine-dependent epilepsy

Keywords: AASA; α-aminoadipic semialdehyde; ATQ; antiquitin; HGMD; Human Genome Mutation Database; IPTG; isopropylthiogalactoside; P6C; Δ1-piperideine 6-carboxylate; PDE; pyridoxine dependent epilepsy; PLP; pyridoxal phosphate; Metabolic epilepsy; Pyridoxine; Mis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Large area UV SiPMs with extremely low cross-talk

Keywords: SiPM; Crosstalk; PDE;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Novel 2-methoxyacylhydrazones as potent, selective PDE10A inhibitors with activity in animal models of schizophrenia

Keywords: PDE10; PDE10A; Phosphodiesterase; Schizophrenia; Hydrazone; Hydrazide; PDE; Enzyme inhibitor; Cognitive;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Hydrogen sulfide stimulates the catalytic activity of a heme-regulated phosphodiesterase from Escherichia coli (Ec DOS)

Keywords: PDE; phosphodiesterase; Ec DOS; EscherichiacoliDirect Oxygen Sensor or heme-regulated phosphodiesterase from Escherichia coli; c-di-GMP; bis-(3′-5′)-cyclic dimeric guanosine monophosphate; l-di-GMP; linear di-GMP, or pGpG; Fe(III); Fe(III)-protoporp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

PM6 and DFT study of free radical scavenging activity of morin

Keywords: HAT; hydrogen atom transfer; SET-PT; single electron transfer followed by proton transfer; SPLET; sequential proton loss electron transfer; BDE; bond dissociation enthalpy; IP; ionisation potential; PDE; proton dissociation enthalpy; PA; proton affinity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research on the quantitative analysis of subsurface defects for non-destructive testing by lock-in thermography

Keywords: Lock-in thermography; PDE; ANN; Differential normalised phase; Quantification

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice

Keywords: PDE; phosphodiesterase; AED; antiepileptic drug; GBP; gabapentin; VGB; vigabatrin; PTZ; pentylenetetrazole; NO; nitric oxide; NOS; nitric oxide synthase; GC; guanylate cyclase; PKG; cGMP-dependent protein kinase; cGMP; guanosine 3′,5′-monophosphate; C

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Early alcohol exposure disrupts visual cortex plasticity in mice

Keywords: FASD; FAS; Ocular dominance; Vinpocetine; PDE

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages

Keywords: AC; adenylate cyclase; CREB; cAMP response element-binding protein; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NO; nitric oxide; PDE; phosphodiesterase; PKA; protein kinase A; PG; prostaglandin; sGC; soluble guanylyl cyclase; YC-1; 3-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways

Keywords: Rolipram; PDE; Glioblastoma; cAMP; PKA; Epac1; Rap1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Epilepsy as a pyridoxine-dependent condition: Quantified urinary biomarkers for status evaluation and monitoring antiepileptic treatment

Keywords: PDE; pyridoxine-dependent epilepsy; PLP; pyridoxal-5-phosphate; AED; antiepileptic drug(s); GAD; glutamic acid decarboxylase; TRP; tryptophan; KYN; kynurenine; IDO; indoleamine 2,3-dioxygenase; 3-HOKYN; 3-hydroxykynurenine; 3-HOAA; 3-hydroxyanthranilic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling

Keywords: BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; ES; embryonic stem cell; GAP; GTPase accelerating protein; GCAPs; guanylyl cyclase activating proteins; GDP; guanosine diphosphate; GTP; guanosine triphosphate; IBMX; isobutylmethylxanthine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Novel triazines as potent and selective phosphodiesterase 10A inhibitors

Keywords: PDE10A; phosphodiesterase 10A; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanine monophosphate; MSN; medium spiny neuron; MK-801; dizocilpine maleate; MED; minimal effective dose; PDE; cyclic nucleotide phosphodiesterase; LMA; locomotor activity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

A multi-mesh finite element method for Lagrange elements of arbitrary degree

Keywords: FEM; Multi-mesh; PDE

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol as a calorie restriction mimetic: therapeutic implications

Keywords: resveratrol; PDE; AMPK; Sirt1; calorie restriction; diabetes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Avanafil for the Treatment of Erectile Dysfunction: A Multicenter, Randomized, Double-Blind Study in Men With Diabetes Mellitus

Keywords: AE; adverse event; BP; blood pressure; ED; erectile dysfunction; IIEF-EF; International Index of Erectile Function erectile function; LS; least square; PDE; phosphodiesterase; SEP; Sexual Encounter Profile;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The chemotypic variation of Sceletium tortuosum alkaloids and commercial product formulations

Keywords: Central nervous system; Chemotype; Mesembrine-type; Phytochemical variation; Sceletium tortuosum; CNS; central nervous system; PCA; principle component analysis; PDE; phosphodiesterase; PLS; partial least squares; QC; quality control;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity

Keywords: AMPAr; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl) propanoic acid receptors; CREB; cAMP response element binding protein; ERK; extracellular signal-regulated kinase; GABAr; gamma-aminobutyric acid receptor; LTP; long-term potentiation; mAChr; muscarinic ch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Müller glia express rhodopsin in a mouse model of inherited retinal degeneration

Keywords: BSA; bovine serum albumin; DAPI; 4′,6-diamidino-2-phenylindole; EDTA; ethylenediaminetetraacetic acid; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCL; ganglion cell layer; GFAP; glial fibrillary acidic protein; INL; inner nuclear layer; IPL; inner

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Ibudilast, a phosphodiesterase inhibitor with anti-inflammatory activity, protects against ischemic brain injury in rats

Keywords: PDE; phosphodiesterase; MCAO; middle cerebral artery occlusion; CCA; common carotid artery; ECA; external carotid artery; ICA; internal carotid artery; CBF; cerebral blood flow; TTC; 2,3,5-triphenyl tetrazolium chloride; RT-PCR; Reverse transcriptase-poly

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

cAMP: Novel concepts in compartmentalised signalling

Keywords: cAMP; cyclic adenosine 3′,5′-monophosphate; GPCR; G protein-coupled receptor; EC coupling; excitation-contraction coupling; FRET; Förster/fluorescence resonance energy transfer; CFP; cyan fluorescent protein; YFP; yellow fluorescent protein; AKAR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners

Keywords: AMPK; AMP-activated protein kinase; ARF; ADP-ribosylation factor; CDK5; cyclin-dependent kinase 5; CEM; caveolin-enriched membrane; CRMP-2; collapsin response mediator protein-2; EGF; epidermal growth factor; EGFR; EGF receptor; GAP; GTPase-activating pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه