Keywords: Alternative splicing; Immunohistochemistry; Afadin; Peptide antibody; Brain; Retina; CA; cornu Ammonis; CNS; central nervous system; DG; dentate gyrus; DIV; days in vitro; DAPI; 4â²,6â²-diamidino-2-phenylindole; En; embryonic day n; ERK; extracellular s
مقالات ISI (ترجمه نشده)
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Keywords: ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CLL; B-cell chronic lymphocytic leukemia; CML; chronic myelogenous leukemia; ERK; extracellular signal-regulated kinase; FN3; fibronectin type-III (domain); GBM; glioblastoma multiforme; JMML
Keywords: Affinity tags; Fusion protein; Proteases; Recombinant protein; Solubility enhancing tag; SUMO; Tag removal; Tandem affinity purification; CBP; Calmodulin-binding peptide; DsbA; Protein disulphide isomerase I; HA; Human influenza hemagglutinin; MBP; Maltos
Keywords: BAC; bacterial artificial chromosome; bp; base pair; CNS; central nervous system; ES; embryonic stem; IL-5Rα; interleukin-5 receptor α subunit; KO; knock out; L-LP; large intestinal lamina propria; LP; lamina propria; PC; peritoneal cavity; PDZ; PSD-95/
Keywords: Prostacyclin receptor; Estrogen receptor; Sterol response element binding protein (SREBP); PDZK1(PDZ-domain-containing protein 1); IKEPP (intestinal and kidney enriched PDZ protein); C/EBP, CCAAT/enhancer binding protein; Rab11; Gene; Cardiovascular; AoSM
Keywords: Auditory pathway; Inner hair cells; Ribbon synapse; Endbulb of Held; Calyx of Held; Synaptopathy; AMPA; Alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate; ATD; Action potential transmission delay; AVCN; Anteroventral cochlear nucleus; CAPS; Ca2+-depen
Keywords: SLRP; small leucine-rich proteoglycan; LRR; leucine-rich repeat; RTK; receptor tyrosine kinase; GAG; glycosaminoglycan; HS; heparan sulfate; HSPG; heparan sulfate proteoglycan; He; heparin; CS; chondroitin sulfate; KS; keratan sulfate; CSPG; chondroitin s
Keywords: AD; Alzheimer's disease; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CDC14A/B; cell division cycle 14A/B; CDK1; cyclin-dependent kinase 1; DDR1; discoidin domain receptor family 1; DLC1; dynein light chain 1; EMT; epithelial-to-
Association between SHANK3 polymorphisms and susceptibility to autism spectrum disorder
Keywords: ASD; Autism spectrum disorder; SNPs; single nucleotide polymorphisms; CHB; Han Chinese in Beijing population; MAF; minimum allele frequency; PCR; polymerase chain reaction; iMLDR; improved multiplex ligation detection reaction; HWE; Hardy-Weinberg equilib
Role of the Crumbs proteins in ciliogenesis, cell migration and actin organization
Keywords: AJ; adherens junction; TJ; tight junction; aPKC; atypical protein kinase C; CRB; crumbs; DLG; discs large; ECM; extracellular matrix; FERM; 4.1 ezrin radixin moesin; LGL; lethal giant larvae; MAGUK; membrane-associated guanylate kinase; MUPP1; multi PDZ d
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ
Keywords: Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;
Junctional adhesion molecule C (JAM-C) dimerization aids cancer cell migration and metastasis
Keywords: ECM; extracellular matrix; EGF; epithelial growth factor; EMT; epithelial to mesenchymal transition; JAM; junctional adhesion molecule; LEF-1; lymphoid enhancer-binding factor 1; MDCK-II; Madin Darby canine kidney II; MMP; matrix metalloproteinase; PDZ; p
Dually modified transmembrane proteoglycans in development and disease
Keywords: ActR; activin type receptor; ALK; activin receptor like kinase; AV; atrioventricular cushion; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; C1; conserved domain 1; C2; conserved domain 2; Cdc42; control protein 42 homolog; CS
Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke
Keywords: 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;
Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine
Keywords: Cystic Fibrosis; Dishevelled; Organoids; Intracellular pH; Neoplasia; CBC; crypt-base columnar cell; CCH; carbachol; CF; cystic fibrosis; Cftr; cystic fibrosis transmembrane conductance regulator; DEP; Dishevelled, Egl-10, and Pleckstrin; Dvl; Dishevelled
Structural and Intermolecular Associations Between Connexin36 and Protein Components of the Adherens Junction-Neuronal Gap Junction Complex
Keywords: AJ-nGJ; adherens junction-neuronal gap junction complex; CNS; central nervous system; Cx36; connexin36; E-cadherin; epithelial cadherin; MesV; mesencephalic trigeminal nucleus; MUPP1; multi-PDZ protein-1; N-cadherin; neural cadherin; nGJs; neuronal ga
PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice
Keywords: Apoptosis; Atherosclerosis; HDL; Macrophage; Signaling; BMT; bone marrow transplantation; CC3; cleaved caspase 3; CHOP; CEBP-homologous Protein; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; ER; endoplasmic reticulum; GRP; glucose regulated prote
EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function
Keywords: βGal; β-Galactosidase; Aβ; amyloid-β; Abl; Abelson murine leukemia viral oncogene homolog; AD; Alzheimer's disease; AMPAR; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; BLA; basolateral amygdala; CaMKI
Paving the Rho in cancer metastasis: Rho GTPases and beyond
Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena
Cell adhesion and matricellular support by astrocytes of the tripartite synapse
Keywords: β (Greek Small Letter Beta): 03B2; α (Greek Small Letter Alpha): 03B1; δ (Greek Small Letter Delta): 03B4; γ (Greek Small Letter Gamma): 03B3; ACM; astrocyte-conditioned medium; AMIGO; adhesion molecule with IG-like domain; AMOG; A Molecule On Glia; A
Tight junction protein ZO-1 controls organic cation/carnitine transporter OCTN2 (SLC22A5) in a protein kinase C-dependent way
Keywords: BSA; bovine serum albumin; DAPI; 2-(4-amidinophenyl)-1H -indole-6-carboxamidine; DMEM; Dulbecco's modified Eagle Medium; DMSO; dimethylsulfoxide; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IGEPAL CA-630; octylphenoxypolyethoxyethanol (nonidet P-40);
Investigation of rabies virus glycoprotein carboxyl terminus as an in vitro predictive tool of neurovirulence. A 3R approach
Keywords: 3R; Post-licensing safety test; Live viral vaccine; Rabies virus; Neurite outgrowth; PDZ;
Low level of PDZ domain containing 1 (PDZK1) predicts poor clinical outcome in patients with clear cell renal cell carcinoma
Keywords: ccRCC; clear cell renal cell carcinoma; PDZK1; PDZ domain containing 1; CAP70; cystic fibrosis transmembrane conductance regulator associated protein of 70Â kDa; DEPs; differentially expressed proteins; GO; gene ontology; KEGG; Kyoto Encyclopedia of Genes
DLG1 polarity protein expression associates with the disease progress of low-grade cervical intraepithelial lesions
Keywords: DLG1; human Discs large; HPV; Human papillomavirus; MAGUKs; membrane-associated guanylate kinase homologues; PDZ; PSD-95/DLG/ZO-1 domains; LSIL; low-grade squamous intraepithelial lesions; HSIL; high-grade squamous intraepithelial lesions; CIN; cervical i
Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications
Keywords: AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Î1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem
Identification of novel transplantable GPCR recycling motif for drug discovery
Keywords: GPCR; β-Adrenergic receptors; Trafficking; PDZ; SNX27; Confocal microscopy;
The role of connexin43-Src interaction in astrocytomas: A molecular puzzle
Keywords: Cx43; connexin43; Cx43CT; C-terminal domain of connexin43; GLUT-3; glucose transporter-3; GSC; glioma stem cells; HIF; hypoxia-inducible factor; HK2; type II hexokinase; IDP; intrinsically disordered protein; IDR; intrinsically disordered region; MAPK; mi
Whirlin increases TRPV1 channel expression and cellular stability
Keywords: Nociception; Thermosensory; PDZ; Synapsis; Cytoskeleton; Pain;
The Paracaspase MALT1
Keywords: NF-κB signaling; Protease; Caspase; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1); ABC; activated B cell-like; ABC-DLBCL; activated B cell-like diffuse large B cell lymphoma; Ac; acetyl; ALL; acute lymphomblastic leukemia; AM
Phospholipase Cβ1b directly binds the SH3 domain of Shank3 for targeting and activation in cardiomyocytes
Keywords: Scaffold protein; Cardiomyocyte; Hypertrophy; Localization; NRVM; neonatal rat ventricular myocytes; PDZ; post synaptic density protein, drosophila disc large tumor suppressor, and zonula occludens-1 protein; PLC; phospholipase C; SH3; Src homology domain
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus
Keywords: PDZ domain; Rabies virus; Neurons; Neuronal signaling; Phosphorylation; Enzymatic regulation; CytoG; C-terminal cytoplasmic tail of G protein; MAST2; microtubule-associated serine and threonine kinase 2; PBM; PDZ binding motif; PDZ; PSD-95/Dlg/ZO-1; PSD;
APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription
Keywords: AP-1; activating protein 1; APPL; adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif; CKI; casein kinase I; Dvl; Dishevelled; GST; glutathione S-transferase; JNK; c-Jun N-terminal kinase; LRP; lo
The atypical 'b' splice variant of phospholipase Cβ1 promotes cardiac contractile dysfunction
Keywords: DGKζ; diacylglycerol kinase ζ; FS; fractional shortening; LVIDd; left ventricular internal diameter at diastole; LVIDs; left ventricular internal diameter at systole; LVPWd; left ventricular posterior wall thickness at diastole; LVPWs; left ventricular
PTEN-PDZ domain interactions: Binding of PTEN to PDZ domains of PTPN13
Keywords: PTEN; PDZ; PTPN13; Protein tyrosine phosphatase; Protein-protein interaction;
Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1
Keywords: 5HT2AR; Serotonin 2A receptor; ACTH; Adrenocorticotropin hormone; ANOVA; Analysis of variance; CAL; CFTR-associated ligand; cAMP; Cyclic adenosine monophosphate; CFTR; Cystic Fibrosis Transmembrane Conductance Regulator; CNS; Central nervous system; CRF;
GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease
Keywords: 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3â²,5â²-cyclic adenosine monophosphate;
PDZK1/NHERF3 Differentially Regulates Corticotropin-releasing Factor Receptor 1 and Serotonin 2A Receptor Signaling and Endocytosis
Keywords: ANOVA; analysis of variance; β 1AR; β 1-adrenergic receptor; β2AR; β2-adrenergic receptor; CRF; corticotropin-releasing factor; CRFR1; CRF receptor 1; CRFR2; CRF receptor 2; ERK1/2; extracellular signal-regulated kinase; GKAP; guanylate kinase-associa
microRNA regulation of Wnt signaling pathways in development and disease
Keywords: Wls; wntless; Porc; porcupine; HSPG; heparin sulfate proteoglycans; ARF; ADP-Ribosylation Factor; Dsh/Dvl; disheveled; DIX; disheveled Axin domain; PDZ; postsynaptic density 95, discs large, zonula occludens-1; DEP; Dvl, Egl-10, Pleckstrin; LRP5/6; low-de
Towards multifunctional magnetic systems through molecular-programmed self assembly of Re(IV) metalloligands
Keywords: nD (n = 1-3); one-, two- and three-dimensional; SMMs; single-molecule magnets; SCMs; single-chain magnets; H2ox; oxalic acid; Me6-[14]ane-N4; (±)-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane; tetren; 3,6,9-triazaundecamethylenediamine;
Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα
Keywords: CPPs; cell-penetrating peptides; GAGs; glycosaminoglycans; HSPGs; heparan sulfate proteoglycans; Syn-4; syndecan-4; CD; cytoplasmic domain; PKCα; protein kinase C-alpha; PtdIns[4,5]P2; phosphatidylinositol (4,5) bisphosphate; Syn-4ÎV; V domain-lacking s
PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway
Keywords: DH; dbl homology; DHR; dock homology region; DMEM; Dulbecco's modified Eagle's medium; Eph; ephrin receptor; FBS; fetal bovine serum; GAP; GTPase activating protein; G-protein; guanosine triphosphate-binding protein; GPCR; heterotrimeric G-protein-coupled
Membrane-associated cargo recycling by tubule-based endosomal sorting
Keywords: BAR; Bin/Amphiphysin/Rvs; ERC; endosome recycling compartment; FERM; 4.1/ezrin/radixin/moesin; GPCR; G protein coupled receptor; PDZ; PSD-95/Dlg1/Zo-1; PX; phox homology; SNX; sorting nexin; TEN; tubular endosomal network; TfR; transferrin receptor; TGN;
Usher protein functions in hair cells and photoreceptors
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CD; cytoplasmic domain; CDH23; cadherin 23; CIB2; calcium integrin binging protein 2; dfcr; deaf circler; EAR; epilepsy associated repeat; FERM; 4.1 protein, ezrin, radixin, moesin; GST; glutath
Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein
Keywords: HPV; E6 protein; PDZ; Cell polarity; Par3; DLG1; human Disc large; E6AP; E6 associated protein; GFP; green fluorescent protein; HA; Influenza Virus Hemagglutinin epitope; HPV; Human Papillomavirus; MAGUKs; membrane-associated guanylate kinase homologues;
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules
Keywords: ELISA, enzyme linked immunosorbent assay; GH, growth hormone; hnRNPA1, heterogeneous nuclear ribonucleoprotein A1; IL6 receptor, interleukin 6 receptor; PSMD9, Proteasome Macropain non-ATPase subunit 9Proteasome; C-termini; PSMD9; PDZ
BDNF mechanisms in late LTP formation: A synthesis and breakdown
Keywords: Brain-derived neurotrophic factor (BDNF); TrkB signaling; Synaptic plasticity; Long-term potentiation (LTP); Protein synthesis; Translation control; Cytoskeletal dynamics; Arc; activity-regulated cytoskeleton-associated protein; AS; Angelman syndrome; AS-
Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95
Keywords: AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionate; DIV; day in vitro; EGFP; enhanced green fluorescent protein; MAGUK; membrane-associated guanylate kinase; PBS; phosphate-buffered saline; PDZ; PSD-95/discs large/zona occludens-1; PSD; postsynaptic
Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling
Keywords: Breast cancer; NHERF1; PDZ; PDGFR; PTEN; EBP50;
Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST
Keywords: PDZ; PSD-95/Drosophila discs-large protein/zonula occludens protein; NHERF; Na+/H+ exchanger regulatory factor; ER; endoplasmic reticulum; ERGIC; ER-Golgi intermediated compartment; EGFP; enhanced green fluorescent protein; COPII; coatomer protein compl
Modification of p115RhoGEF Ser330 regulates its RhoGEF activity
Keywords: ATRA; All-trans retinoic acid; DH; Dbl homology; DMEM; Dulbecco's modified Eagle's medium; FBS; Fetal bovine serum; GAP; GTPase activating protein; HPLC-MS/MS; High pressure/tandem mass spectrometry; LARG; Leukemia-associated RhoGEF; LC/MS/MS; Liquid ch