کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8842173 1615351 2018 75 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cell adhesion and matricellular support by astrocytes of the tripartite synapse
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Cell adhesion and matricellular support by astrocytes of the tripartite synapse
چکیده انگلیسی
Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes enwrap the neuronal components of the tripartite synapse, and due to this close interaction they are perfectly positioned to modulate neuronal communication. The interaction between astrocytes and synapses is facilitated by cell adhesion molecules and matricellular proteins, which have been implicated in the formation and functioning of tripartite synapses. The importance of such neuron-astrocyte integration at the synapse is underscored by the emerging role of astrocyte dysfunction in synaptic pathologies such as autism and schizophrenia. Here we review astrocyte-expressed cell adhesion molecules and matricellular molecules that play a role in integration of neurons and astrocytes within the tripartite synapse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neurobiology - Volumes 165–167, June–August 2018, Pages 66-86
نویسندگان
, , ,