Keywords: Actin dynamics; Rho GTPases; dendritic spines; postsynapse; Abi-1; Abelson interacting protein 1; Abp1; actin binding protein 1; ACTN4; α-actinin-4; ADF; actin-depolymerizing factor; ADHD; attention deficit/hyperactivity disorder; ADNP; activity-dependen
مقالات ISI (ترجمه نشده)
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Keywords: Ketamine; Depression; NMDAR; GluN2B; AMPAR; Ambient glutamate; Cortex; Inhibition; Disinhibition; NMDA receptor; AMPA receptor; Homeostatic synaptic plasticity; Protein synthesis; Folimycin (PubChem CID: 6438151); Glutamate (PubChem CID: 33032); Ketamine
Keywords: mEPSC; miniature excitatory postsynaptic current; Hippocampus culture; Ethanol; Calcium; Synapses; Dendritic spines;
Keywords: Corticosterone; Noradrenaline; Metaplasticity; mEPSC; PTSD; Consolidation;
Extinction and Reinstatement of Cocaine-seeking in Self-administering Mice is Associated with Bidirectional AMPAR-mediated Plasticity in the Nucleus Accumbens Shell
Keywords: ACSF; artificial cerebral spinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; COC; cocaine; CUE; cocaine-associated discrete cue light; D-AP5; D-aminophosphonovaleric acid; FR1; fixed ratio 1 schedule of reinforcement; GAB
Functional significance of O-GlcNAc modification in regulating neuronal properties
Keywords: PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF
UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism
Keywords: NLGN3; neuroligin3; ASDs; autism spectrum disorders; UPR; unfolded protein response; ER; endoplasmic reticulum; WT; wild type; mEPSC; miniature excitatory post-synaptic currents; DMSO; dimethyl sulfoxide; ATF6; activating transcription factor 6; BiP; immu
EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function
Keywords: βGal; β-Galactosidase; Aβ; amyloid-β; Abl; Abelson murine leukemia viral oncogene homolog; AD; Alzheimer's disease; AMPAR; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; BLA; basolateral amygdala; CaMKI
Cell adhesion and matricellular support by astrocytes of the tripartite synapse
Keywords: β (Greek Small Letter Beta): 03B2; α (Greek Small Letter Alpha): 03B1; δ (Greek Small Letter Delta): 03B4; γ (Greek Small Letter Gamma): 03B3; ACM; astrocyte-conditioned medium; AMIGO; adhesion molecule with IG-like domain; AMOG; A Molecule On Glia; A
The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord
Keywords: [Ca2+]i; intracellular Ca2+ concentration; 5-HT; serotonin; Ach; acetylcholine; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin;
Prostaglandin E2 modulates presynaptic regulation of GnRH neurons via EP4 receptors in accordance with estrogen milieu
Keywords: D1; diestrus 1; E2; 17β-estradiol; EP1; prostaglandin E receptor 1; EP2; prostaglandin E receptor 2; EP4; prostaglandin E receptor 4; GnRH; gonadotropin-releasing hormone; mEPSC; miniature excitatory postsynaptic current; OVX; ovariectomized; PGE2; prost
Electrophysiological properties of neurons and synapses in the lateral habenular complex (LHb)
Keywords: AMPA-R; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; 5-HT; 5-hydroxytryptamine (serotonin); EP; entopeduncular nucleus (rodent equivalent of the internal globus pallidus in higher mammals); GABA; gamma-aminobutyric acid; GABA-A receptor
Enkephalin and neuropeptide-Y interaction in the intergeniculate leaflet network, a part of the mammalian biological clock
Keywords: ACSF; artificial cerebro-spinal fluid; AP-5; 2-amino-5-phosphonopentanoic acid; Bic; bicuculline methiodide; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; EGTA; ethylene glycol tetraacetic acid; ENK; enkephalin; GABA; γ-aminobutyric acid; GGT; geniculo-gen
Modulation of hippocampal synapse maturation by activity-regulated E3 ligase via non-canonical pathway
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BCA; bicinchoninic acid; CA; Cornu Ammonis; DG; Dentate Gyrus; DIV; days in vitro; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; Glial Fibrilary Acidic Protein; GFP; Green Fluorescent P
Research reportCRMP4 regulates dendritic growth and maturation via the interaction with actin cytoskeleton in cultured hippocampal neurons
Keywords: CRMP4; Actin; Dendritic development; Spine; mEPSC; Hippocampal neuron;
The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission
Keywords: GABA; Galanin; Glutamate; mEPSC; NAX-5055; Seizure activity; Toxicity; Vesicular neurotransmitter release; ANOVA; analysis of variance; AUC; area under the curve; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Essential Medium; f.c.; fin
Serotonin differentially modulates excitatory and inhibitory synaptic inputs to putative sleep-promoting neurons of the ventrolateral preoptic nucleus
Keywords: VLPO; Single-cell RT-PCR; Gal-GFP neurons; EPSCs; IPSCs; NREM; 5-HT; serotonin; 5-HTR; serotonergic receptor; Gal; galanin; mEPSC; miniature excitatory post-synaptic current; mIPSC; miniature inhibitory post-synaptic current; NA; noradrenaline; PSP; putat
Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy
Keywords: ACSF; artificial cerebrospinal fluid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANDRO; andrographolide; APV; 2-amino-5-phosphonovaleric acid; AraC; 1-β-D-arabinofuranosylcytosine; CaMKII; calmodulin-dependent protein kinase II
Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis
Keywords: 2-AG; 2-arachidonoylglycerol; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; hypothalamic arcuate nucleus; CRH; corticotropin-releasing hormone; DSI; depolarization-induced suppression of inhibition; ERK; extracellular signal-regul
Palmitoylation in Alzheimerâ¿¿s disease and other neurodegenerative diseases
Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer⿿s disease; ADAM17; a disintegrin and metalloproteinase 17; AICD; APP intracellular domain; AKAP79; A-kinase anchoring protein 79; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APP; amy
Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS
Keywords: ALS; amyotrophic lateral sclerosis; SOD1; superoxide dismutase-1; AMPA; α-amino-3-hydroxy-5-methylisoxazole propionic acid; VGCC; voltage-gated Ca2 + channel; PCCa; persistent Ca2 + current; mSOD1; mutant SOD1; TEA-Cl; tetraethylammonium chloride; 4-AP
Synaptic structure and function are altered by the neddylation inhibitor MLN4924
Keywords: NEDD8; neural precursor cell expressed, developmentally down-regulated 8; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Ubc12; ubiquitin carrier protein 12; RING; really interesting new gene; HECT; homologous to the E6-AP carboxyl
The role of chromatin repressive marks in cognition and disease: A focus on the repressive complex GLP/G9a
Keywords: AAV-Cre; adeno-associated virus with Cre recombinase; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; BIX-01924; G9a inhibitor; CA1; cornu ammonis 1; DNA; deoxyribonucleic acid; Drd1; dopamine recep
Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro
Keywords: ACSF; artificial cerebral spinal fluid; DOR; delta opioid receptor; DRG; dorsal root ganglion; EGFR; epidermal growth factor receptor; GSK-3β; glycogen synthase kinase-3β; mEPSC; miniature excitatory postsynaptic current; NMDA; N-methyl-d-aspartate; OIH
Orexins/hypocretins modulate the activity of NPY-positive and -negative neurons in the rat intergeniculate leaflet via OX1 and OX2 receptors
Keywords: Bic; bicuculline methbromide; dLGN; dorsal part of lateral geniculate nucleus; DMSO; dimethyl sulfoxide; ENK; enkephalin; GHT; geniculo-hypothalamic tract; IGL; intergeniculate leaflet; Kyn; kynurenic acid sodium salt; mEPSC; miniature excitatory postsyna
Statistical models suggest presence of two distinct subpopulations of miniature EPSCs in fast-spiking interneurons of rat prefrontal cortex
Keywords: ACSF; artificial cerebrospinal fluid; CP-AMPARs; Ca2+-permeable GluA2-lacking AMPA receptors; CV; coefficient of variation; EGTA; ethylene glycol tetraacetic acid; FSI; fast-spiking interneuron; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; m
Artemisia santolinifolia enhances glutamatergic neurotransmission in the nucleus of the solitary tract
Keywords: CG; CalciumGreen 1-dextran; DNQX; 7-dinitroquinoxaline-2,3-dione; mEPSC; miniature excitatory postsynaptic current; NST; nucleus of the solitary tract; PMI-5011; Artemisia dracunculus L; ROI; region of interest; SANT; Artemisia santolinifolia; SCO; Artemi
Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration
Keywords: LRRK2; leucine rich repeat kinase 2; LRRK2-3HA; C-terminal 3Ã-hemagglutinin tagged LRRK2; cDNA; complementary deoxyribonucleic acid; mEPSC; miniature excitatory postsynaptic current; PD; Parkinson's disease; AMPA; (2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-
Hydrogen-rich saline prevents remifentanil-induced hyperalgesia and inhibits MnSOD nitration via regulation of NR2B-containing NMDA receptor in rats
Keywords: ANOVA; analysis of variance; EGFR; epidermal growth factor receptor; HRS; hydrogen-rich saline; mEPSC; miniature excitatory postsynaptic current; MnSOD; manganese superoxide dismutase; NMDA; N-methyl-d-aspartate; NMDAR; NMDA receptor; NS; normal saline; O
Astrocyte calcium microdomains are inhibited by Bafilomycin A1 and cannot be replicated by low-level Schaffer collateral stimulation in situ
Keywords: Calcium; Group I mGluRs; Bafilomycin A1; mEPSC;
Arg kinase signaling in dendrite and synapse stabilization pathways: Memory, cocaine sensitivity, and stress
Keywords: Arg; Abl-related gene; F-actin; filamentous actin; SH2, SH3; Src homology domain 1,2; P21, P42; postnatal day 21, 42; argKD; arg knockdown; p190; p190RhoGAP, 190Â kDa GTPase activating protein for Rho; p120; p120RasGAP, 120Â kDa GTPase activating protein
Molecular mechanisms of COMPLEXIN fusion clamp function in synaptic exocytosis revealed in a new Drosophila mutant
Keywords: AZ; active zone; BRP; BRUCHPILOT; CPX; COMPLEXIN; DLM; dorsal longitudinal flight muscle; EPSC; excitatory postsynaptic current; mEPSC; miniature excitatory postsynaptic current; mEPSP; miniature excitatory postsynaptic potential; NSYB; neuronal-SYNAPTOBR
Research ReportCharacterization of nociceptive responses to bee venom-induced inflammation in neonatal rats
Keywords: mEPSC; the miniature excitatory postsynaptic current; EPSCs; excitatory postsynaptic currents; IPSCs; Inhibitory postsynaptic currents; α2-AR; α2-adrenergic receptor; PAG; the midbrain periaqueductal grey; RVM; retroventral medulla; Development; Bee ven
Research reportAcute neuregulin-1 signaling influences AMPA receptor mediated responses in cultured cerebellar granule neurons
Keywords: AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; CGCs; cerebellar granule cells; chemLTP; high-glycine/0 Mg2+-induced LTP; KA; kainate; LTP; long-term potentiation; mEPSC; miniature excitatory post-synaptic currents; NMDA; N-methyl-d-aspartic ac
α-Tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus
Keywords: AMPA; α-amino-3-hydroxy-5-methylisoazol-4-propionate; AP5; d-amino-5-phosphonovalerate; α-TOH; α-tocopherol; α-TP; α-tocopheryl phosphate; CB1R; cannabinoid receptor type 1; CP; CP55,940; DSE; depolarization-induced suppression of excitation; eCB; en
Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus
Keywords: sphingosine kinase; sphingosine 1-phosphate; S1P receptor; long-term potentiation; hippocampus; memory; ACSF; artificial cerebrospinal fluid; eEPSC; evoked excitatory postsynaptic current; fEPSP; field excitatory postsynaptic potentials; HACPT; 2-(p-hydro
Enhanced excitatory and reduced inhibitory synaptic transmission contribute to persistent pain-induced neuronal hyper-responsiveness in anterior cingulate cortex
Keywords: persistent nociception; anterior cingulate cortex; sEPSC; sIPSC; mEPSC; mIPSCACC, anterior cingulate cortex; BV, bee venom; EAA, excitatory amino acid; IAA, inhibitory amino acid; mEPSC, miniature excitatory post-synaptic current; mIPSC, miniature inhibit
Cell-dependent physiological synaptic action of morphine in the rat habenular nucleus: Morphine both inhibits and facilitates excitatory synaptic transmission
Keywords: Morphine; Opioid; Thalamus; Habenular nucleus; mEPSC
Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain
Keywords: CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CPPG; (RS)-α-cyclopropyl-4-phosphonophenylglycine; eEPSCs; evoked excitatory postsynaptic current; GDP-β-S; guanosine 5â²-O-(2-thiodiphosphate); IPSC; inhibitory postsynaptic current; l-AP4; l(+)-2-amino-4-ph
In developing hippocampal neurons, NR2B-containing N-methyl-d-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death
Keywords: apoptosis; necrosis; extrasynaptic; neuroprotection; NR2A; mEPSC; miniature excitatory postsynaptic current; NMDA; N-methyl-d-aspartate; NMDAR; N-methyl-d-aspartate receptor; NR2A-NMDAR; NR2A-containing N-methyl-d-aspartate receptor; SGG; salt-glucoseâ
Epidermal growth factor administered in the periphery influences excitatory synaptic inputs onto midbrain dopaminergic neurons in postnatal mice
Keywords: neurotrophic factor; dopamine; ventral tegmental area; AMPA; ErbB1; ACSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; AP; alkaline phosphatase; CNQX; 6-cyano-7-nitoroquinoxaline-2,3-dione; DIG; digoxigenin; EGF; epidermal growth factor; E
Parasynaptic signalling by fast neurotransmitters: the cerebellar cortex
Keywords: cerebellum; spillover; synaptic transmission; glutamate; GABA; LTD; long-term depression; mEPSC; miniature EPSC;
Recovery of network-driven glutamatergic activity in rat hippocampal neurons during chronic glutamate receptor blockade
Keywords: 1X; 100 μM/10 μM AP5/CNQX concentrations or chronically treated culture condition; 2X; 200 μM/20 μM AP5/CNQX concentrations or chronically treated culture condition; 5X; 500 μM/50 μM AP5/CNQX concentrations or chronically treated culture condi
Regulation of AMPA receptors and synaptic plasticity
Keywords: long-term potentiation; long-term depression; glutamate; receptor trafficking; receptor phosphorylation; ABP; AMPA receptor-binding protein; AMPAR; AMPA receptor; Arc; activity-regulated cytoskeleton-associated protein; Aβ; beta-amyloid; BAR; Bin/amphyph
Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons
Keywords: Down syndrome; mEPSC; Ts65Dn; Hippocampus
Nitric oxide modulates the firing rate of the rat supraoptic magnocellular neurons
Keywords: patch clamp; supraoptic neurons; firing rate; hyperpolarizing after-potential; nitric oxide; AVP; vasopressin; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; dl-AP5; dl-2-amino-5-phosphonovaleric acid; d-NAME; NÏ-Nitro-d-arginine methyl ester hydrochloride;
Nongenomic regulation of glutamatergic neurotransmission in hippocampus by thyroid hormones
Keywords: thyroxine; 3,3â²,5â²-l-triiodothyronine; NMDA receptors; AMPA receptors; patch-clamp; BME; basal Eagle's Medium; DIV; days in vitro; DME; Dulbecco's Modified Basal Eagle's medium; IC50; agonist concentration eliciting the half-maximal response; KA
Making quantal analysis more convenient, fast, and accurate: User-friendly software QUANTAN
Keywords: Synaptic transmission; Quantal content; EPSC; mEPSC; Quantal size; Deconvolution; Synaptic latency; Binomial model;
Ivermectin potentiates ATP-induced ion currents in cortical neurones: Evidence for functional expression of P2X4 receptors?
Keywords: Ivermectin; Cortex; mEPSC; Purinoceptor; P2X4; Purinergic neurotransmission
Increase in AMPA receptor-mediated miniature EPSC amplitude after chronic NMDA receptor blockade in cultured hippocampal neurons
Keywords: Synaptic plasticity; mEPSC; NMDA receptor; AMPA receptor; AP5; Neuronal culture;