Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Feeding management; Fatty liver; Light control; Nutritional stress; Steatosis; FA; fatty acids; TG; triglyceride; NEFA; non-esterified free fatty acids; VLDL; very low-density lipoprotein; CP; crude protein; Fabp1; fatty acid binding protein 1; Srebp1; st
مقالات ISI گیرنده پروتئینی فعال پروکسایزوم α (ترجمه نشده)
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Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Dibutyryl adenosine cyclophosphate; Growth performance; Lipid metabolism; Peroxisome proliferator-activated receptor α; Hormone sensitive glycerol three lipase; Early weaning piglets;
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NIC; nicotine; JAK2; janus tyrosine kinase; STAT3; signal transducer and activator of transcription 3; SOCS3; suppressor of cytokine signaling 3; OB-R; leptin receptors; GD; gestational day; isSWAT; interscapular subcutaneous white adipose tissue; igSWAT;
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; PTP1B; protein tyrosine phosphatase 1B; CNS; central nervous system; HFD; high fat diet; NPY; neuropeptide Y; AMPK; 5' AMP-activated protein kinase; BAT; brown adipose tissue; AF; albiflorin; hAMSCs; human adipose tissue-derived mesenchymal stem cells; PP
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Dio2; type II iodothyronine deiodinase; Dio3; type III iodothyronine deiodinase; TRα and TRβ; thyroid hormone receptor α and β; SOD; superoxide dismutase; HSP; heat shock protein; PHGPx; phospholipid hydroperoxide glutathione peroxidase; CPT; carnitin
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NASH; NAFLD; HCV; HBV; ROS; AFLD; alcoholic fatty liver disease; AMPK; adenosine monophosate-activated protein kinase; ASH; alcoholic steatohepatitis; ASK1; mitogen-activated protein kinase kinase kinase 5; ATP; adenosine triphosphate; CoA; coenzyme A;
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; AKI; acute kidney injury; α-SMA; αâsmooth muscle actin; CKD; chronic kidney disease; ECM; extracellular matrix; CTGF; (connective tissue growth factor); DC; dendritic cells; DTR; diphtheria toxin receptor; EGF; epidermal growth factor; EMT; epithelial
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Flavonoids; Quercetin; Plant-derived polyphenol; Cardiovascular action; Bioassay; CVD; Cardiovascular disease; eNOS; endothelial nitric oxide synthase; BcL2; B-cell lymphoma 2; MDA; malonaldehyde; TNFα; tumor necrosis factor α; IL-6; Interleukin 6; PPAR
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; IL-6; interleukin-6; ND; normal diet; HFD; high fat diet; FAs; fatty acids; CD36; cluster of differentiation 36; MCP-1; monocyte chemoattractant protein 1; PPARα; peroxisome proliferator-activated receptor α; CPT-1; carnitine palmitoyltransferase 1; End
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; DAC; 5-Aza-2â²-deoxycytydine; DNMT; DNA methyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; HDACì; HDAC inhibitors; IL-2; interleukin-2; INS; insulin; LADA; latent autoimmune diabetes in adults; miRNA; microRNA; PBMCs; peripher
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; PPARα; peroxisome proliferator-activated receptor α; AOX; alternative oxidase; ACC; acetyl-CoA carboxylase; SREBP-1c; sterol regulatory element binding protein-1c; DGAT; diacylglycerol O-acyltransferase; ACS; acetyl-CoA synthetase; TNF-α; tumor necrosi
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Lysosome-associated membrane protein-2; Autophagy; Diabetes; Obesity; Lysosome; ATF4; activating transcription factor 4; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; Cidea; cell death-inducing DNA fragmentation factor-α-like effector A; FGF21; fibro
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; FATP1; Fatty acid transport protein 1; FA; Fatty acids; MHD; Metabolic heart disease; ROS; Reactive oxygen species; PPARα; Peroxisome proliferator-activated receptor α; PGC1α; PPARγ coactivator-1 α; DG; Diacylglycerol; CREB; Cyclic AMP responsive ele
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; AbFW; abdominal fat weight; ADD-1; adipocyte determination and differentiation-dependent factor 1; ANOVA; analysis of variance; BJY; Beijing-You; C/EBPα; CCAAT/enhancer-binding protein factors α; C/EBPβ; CCAAT/enhancer-binding protein factors β; GLM;
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ACADl; acyl-CoA dehydrogenase, long chain; ACADm; acyl-CoA dehydrogenase, medium chain; ACADvl; acyl-CoA dehydrogenase, very long chain; AMPK; 5â² AMP-activated protein kinase; CD36; cluster of differentiation 36; CPT2; carnitine palmitoyltransferase II;
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ALD; alcoholic liver disease; BBR; berberine; ROS; reactive oxygen species; TBARS; TBA reactive substances; GSH; glutathione; CYP2E1; cytochrome P450 2E1; ALD; alcoholic liver disease; PPARα; peroxisome proliferator-activated receptor α; PGC-1α; peroxi
G0S2a1 (G0/G1 switch gene 2a1) is downregulated by TNF-α in grass carp (Ctenopharyngodon idellus) hepatocytes through PPARα inhibition
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ATGL; adipose triglyceride lipase; HSL; hormone-sensitive lipase; MGL; monoacylglycerol lipase; ORF; open reading frame; TAG; triacylglycerol; FA; fatty acid; G0S2; G0/G1 switch gene 2; PPAR; Proliferator-Activated Receptor; TSGD; teleost-specific genome
Roles of microRNA in prostate cancer cell metabolism
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; AMPK; adenosine monophosphate-activated protein kinase; HIF-1α; hypoxia-inducible factor 1-alpha; mTOR; mammalian target of rapamycin; PI3K/AKT; phosphatidylinositol 3-kinase; ATP; adenosine triphosphate; TCA cycle; tricarboxylic acid cycle; GLUTs; gluco
TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP-ATF response elements in the Fgf21 promoter
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ATF; activating transcription factor; C/EBP; CCAAT/enhancer-binding protein; ER; endoplasmic reticulum; FGF21; fibroblast growth factor 21; MEF; mouse embryonic fibroblast; PPARα; peroxisome proliferator-activated receptor α; TRIB3; Tribbles homolog 3;
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;
A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Propaquizafop; Carcinogenicity; Rodent hepatocarcinogenesis; PPARα; Liver; Peroxisome proliferators; Mode of action; Human relevance framework; Enzyme induction; Rats; ACO; Acyl-CoA oxidase; bw; body weight; BrdU; bromodeoxyuridine; CAT; catalase; CYP; c
Binding interactions of halogenated bisphenol A with mouse PPARα: In vitro investigation and molecular dynamics simulation
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Fluorescence polarization; Electrostatic potential; Molecular docking; Halogenated bisphenol A; Peroxisome proliferator-activated receptor α;
Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho
Mitochondrial uncoupling, ROS generation and cardioprotection
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ANT; adenine nucleotide translocator; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CcO; cytochrome c oxidase; DNP; 2,4-dinitrophenol; FCCP; carbonyl cyanide p-trifluoromethoxyphenylhydrazone; GSIS; glucose-stimulated insulin secretion; HNE; 4-hydroxy-2
Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Biliary excretion; PPARα; Bile acids; Gender difference; 1oBAs; Primary bile acids; 2oBAs; secondary bile acids; 12-OH; 12-hydroxylated bile acid; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; Baat; bile acid CoA:amino acid N-acyltr
Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; CREBH; PPARα; Liver Injury; Mouse Model; Steatohepatitis; AHF; atherogenic high-fat; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CREBH; hepatocyte-specific cAMP-responsive element binding protein; DECR; 2,4 dienoyl-coA reductase; FAO;
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa
The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic proteins via PPARα down-regulation
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; CYP2E1; cytochrome P450 2E1; ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophin-3; DMSO; dimethyl sulfoxide; ChIP; chroma
The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka LongâEvans Tokushima fatty rats and HepG2 cells
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Alnus japonica; Curcuma longa; Massa Medicata Fermentata; Peroxisome proliferator-activated receptor α; Fatty acid oxidation; Lipogenesis;
Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di
Protective effects of gomisin N against hepatic steatosis through AMPK activation
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Gomisin N; Nonalcoholic fatty liver disease; Lipogenesis; AMP-activated protein kinase; Sterol regulatory element-binding protein 1c; High-fat diet; ACC; Acetyl-CoA carboxylase; AMPK; Adenosine monophosphate (AMP)-activated protein kinase; CPT 1; Carnitin
Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; CYP2A6; Cytochrome P450 2A6; CYP2E1; Cytochrome P450 2E1; Cyp2e1â/â mice; Cyp2e1 knockout mice; CYP2A5; Cytochrome P450 2A5; Cyp2a5â/â mice; Cyp2a5 knockout mice; NRF2; nuclear factor-erythroid 2-related factor 2; Nrf2â/â mice; Nrf2 knockout m
Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ
Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CCK8; Cell Counting Kit-8; DAB; 3,3â²-diaminobenzidine; DAPI; 4â², 6-diamidino-2-phenylindole; DCFH-DA; 2â²,7â²-Dichlorofluorescein diacetate; DHE; dihydroethidium; D
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; AhR; aryl hydrocarbon receptor; CAR; constitutive activated receptor; DEHP; di-(2-ethylhexyl)phthalate; ERα; estrogen receptor α; ERE; estrogen response element; GH; growth hormone; LXR; liver X receptor; Nrf2; nuclear factor erythroid-2-related factor
Oleic acid-derived oleoylethanolamide: A nutritional science perspective
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ABHD4; α/β-hydrolase domain-containing protein 4; AEA; arachidonoylethanolamide; A:G; android-to-gynoid; CHO; carbohydrate; DHEA; docosahexaenoylethanolamide; DXA; dual-energy X-ray absorptiometry; E; energy; EEA; elaidoylethanolamide; FAAH; fatty acid
Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFSC; high fructose corn syrup; ALT; alanine aminotransferase; AST; aspartate aminotransferase; RBP4; retinol binding protein 4; FGF21; fibroblast growth factor 21; CRP; C-reac
An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Bile Acids; Farnesoid X Receptor; Metabolic Disease; Ceramides; BSH; bile salt hydrolase; CA; cholic acid; cAMP; cyclic adenosine monophosphate; CDCA; chenodeoxycholic acid; CYP; cytochrome P450s; CYP7A1; CYP with cholesterol 7α-hydroxylase; DCA; deoxych
Carnitine palmitoyltransferase 1C: From cognition to cancer
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ACC; acetyl-CoA carboxylase; ACO; aconitase; AICAR; 5-aminoimidazole-4-1-b-d-ribofuranoside; AMPK; AMP-dependent protein kinase; Arc; Arcuate; BSX; brain-specific homeobox; cAMP; cyclic AMP; CNS; central nervous system; COT; carnitine octanoyltransferase;
Beneficial effects of neomangiferin on high fat diet-induced nonalcoholic fatty liver disease in rats
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Neomangiferin; Nonalcoholic fatty liver; Peroxisome proliferator-activated receptor α; Fatty acid transport protein 2; High-fat diet;
High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Epigenetics; Metabolic syndrome; Nutrition; Corn syrup; Gene expression; Dyslipidemia; PPARα; peroxisome proliferator-activated receptor α; CPT1&Agr; carnitine palmitoyltransferase 1A; LDLR; low density lipoprotein receptor; MTTP; microsomal triglycerid
The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Nitric oxide; Hepatoprotection; Liver steatosis; Glucose tolerance; Fatty acid metabolism; ABCA1; ATP-binding cassette transporter family member 1; ACC; native isoform acetyl-CoA carboxylase; Akt; serine/threonine-protein kinase; ALT; alanine aminotransfe
Short communication: The pharmacological peroxisome proliferator-activated receptor α agonist WY-14,643 increases expression of novel organic cation transporter 2 and carnitine uptake in bovine kidney cells
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; bovine kidney cells; novel organic cation transporter 2; peroxisome proliferator-activated receptor α;
NPC1, intracellular cholesterol trafficking and atherosclerosis
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NPC1; Niemann-Pick type C1; LE/LY; late endosome/lysosome; LDL; low-density lipoprotein; LDL-C; LDL-cholesterol; ER; endoplasmic reticulum; SSD; sterol-sensing domain; NTD; N-terminal domain; apoE; apolipoprotein E; LXR; liver X receptor; OSBP; oxysterolÂ
Research ArticleThyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; NAFLD; non-alcoholic fatty liver disease; SCH; subclinical hypothyroidism; TSH; thyrotropin; T4; free thyroxine; TG; triglyceride; SREBP-1c; sterol regulatory element-binding protein-1c; PPARα; peroxisome proliferator-activated receptor α; AMPK; AMP-act
Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty
The ethanol extract of Zingiber zerumbet Smith attenuates non-alcoholic fatty liver disease in hamsters fed on high-fat diet
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; High-fat diet; Non-alcoholic fatty liver disease; Peroxisome proliferator-activated receptor α; Sterol regulatory element-binding protein-1c; Zingiber zerumbet rhizome;
Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; Ad; adiponectin; NEB; negative energy balance; AdipoR1; adiponectin receptor 1; AdipoR2; adiponectin receptor 2; AMPK; AMP-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; SREBP-1c; sterol regulatory element-binding protein
Punctum on two different transcription factors regulated by PGC-1α: Nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2
Keywords: گیرنده پروتئینی فعال پروکسایزوم α; γGCS; gamma-glutamylcysteine synthetase; ARE; antioxidant responsive element; BAT; brown adipose tissue; CNC; Cap 'n' collar; COX; cytochrome c oxidase; CR; calorie restriction; CREB; cAMP response element-binding protein; ERRs; Estrogen-related rece