Keywords: مطالعه فارماکوکینتیک; Tasimelteon; Anhydrates; Hemihydrate; Pharmacokinetic study;
مقالات ISI مطالعه فارماکوکینتیک (ترجمه نشده)
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Keywords: مطالعه فارماکوکینتیک; Diarylpentadienone; Prostate cancer; Antiproliferative activity; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; BGE; background electrolyte; CD; cyclodextrin; CM-β-CD; carboxymethyl-β-cyclodextrin; CSEI; cation-selective exhaustive injection; EOF; electroosmotic flow; FESI; field-enhanced sample injection; HP-β-CD; hydroxypropyl-β-cyclodextrin; S-β-CD; sulfate
Keywords: مطالعه فارماکوکینتیک; Solid-SNEDDS; Pharmacokinetic study; Spray drying; Dissolution; Stability study;
Simple protein precipitation extraction technique followed by validated chromatographic method for linezolid analysis in real human plasma samples to study its pharmacokinetics
Keywords: مطالعه فارماکوکینتیک; LNZ; linezolid; IS; internal standard; LLOQ; lower limit of quantification; Linezolid; HPLC; Human plasma; Protein precipitation; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; Nanofluidic LC-chip-MS/MS; UHPLC-MS/MS; Whole blood microsampling; Mass spectrometry; Pharmacokinetic study; Estrogens;
Keywords: مطالعه فارماکوکینتیک; 2-morpholinoquinoline based 1,2,4-oxadiazole; Antimicrobial activity; Molecular docking; Pharmacokinetic study; Cytotoxicity;
Keywords: مطالعه فارماکوکینتیک; Whole blood microsampling; Volumetric absorptive microsampling; Dried blood spot; Capillary microsampling; Dried plasma spot; Pharmacokinetic study; Toxicokinetic study; Therapeutic drug monitoring;
Fast and efficient zirconia-based reversed phase chromatography for selective determination of triptans in rat plasma
Keywords: مطالعه فارماکوکینتیک; Zirchrom; Polybutadiene; Chromatography; Triptans; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; Tip-loaded microneedle; Donepezil hydrochloride; High content; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Timolol maleate; Hydrogel contact lenses; Ring implantation; Controlled drug delivery; Pharmacokinetic study; Pharmacodynamic study;
Keywords: مطالعه فارماکوکینتیک; Caffeine; Antidepressant drugs; Forced swim test; Pharmacokinetic study; Mice
Keywords: مطالعه فارماکوکینتیک; UPLC-MS; Morroniside; Loganin; Shanzhuyu extract; Chronic kidney disease; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; UFLC–MS/MS; Danmu injection; Danmu tablet; Alkaloid components; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Steroidal saponins; UHPLC–MS/MS; Rat plasma; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Adefovir; Liquid chromatography–tandem mass spectrometry; Solid phase extraction; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Bosentan; Glimepiride; UPLC–MS/MS; Human plasma; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Darifenacin; HPLC; Method of validation; Mouse plasma; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; Andrographis paniculata; HMPL-004; Chemical components; LC-MS/MS; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; Depression; Venlafaxine; Alginate nanoparticles; Forced swim test; Pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Alfuzosin; Solifenacin; Fixed dose combination; Bioequivalence; 90% Confidence interval; Pharmacokinetic study;
Keywords: مطالعه فارماکوکینتیک; RRLC-ESI-Q-TOF-MS; Yuanhu Zhitong prescription; Cerebrospinal fluid; Pharmacokinetic study;
A validated LC-MS/MS method for simultaneous determination of linagliptin and metformin in spiked human plasma coupled with solid phase extraction: Application to a pharmacokinetic study in healthy volunteers
Keywords: مطالعه فارماکوکینتیک; ALG; alogliptin; AUC0-t and AUC0-â; the areas under the plasma concentration-time curve; Cmax; maximum plasma concentration; DPP-IV; dipeptidyl peptidase; ER; extraction recovery; GIP; glucose-dependent insulinotropic polypeptide; GLP 1; glucagon-
Quantitative analysis of the cyclic peptide GG-8-6 in rat plasma using LC-MS/MS and its application to a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; LC-MS/MS; liquid chromatographic method with tandem mass spectrometric detection; HCC; hepatocellular carcinoma; GG-8-6; cyclo-(Val1-Leu2-Pro3-Ile4-Leu5-Leu6-Leu7-Val8-Leu9); UV; ultraviolet; IS; internal standard; A6; cyclo-(Val1-Leu2-Pro3-Ala4-Leu5-Leu6
Development, characterization & invivo evaluation of proniosomal based transdermal delivery system of Atenolol
Keywords: مطالعه فارماکوکینتیک; Proniosomes; Atenolol; Niosomes; Pharmacokinetic study; Transdermal delivery;
QBD-based systematic development of BosentanSNEDDS: Formulation, characterization and pharmacokinetic assessment
Keywords: مطالعه فارماکوکینتیک; Bosentan; Self-emulsifying drug delivery system; Quality by design; Central composite design; Pharmacokinetic study;
Determination and pharmacokinetic study of Enasidenib in rat plasma by UPLC-MS/MS
Keywords: مطالعه فارماکوکینتیک; Enasidenib; UPLC-MS/MS; Rat plasma; Pharmacokinetic study;
A facile synthesis of 3D NiFe2O4 nanospheres anchored on a novel ionic liquid modified reduced graphene oxide for electrochemical sensing of ledipasvir: Application to human pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Ledipasvir; 3D NiFe2O4 nanospheres; Reduced graphene oxide; Morpholinium acid sulphate; Harvoni® tablets; Pharmacokinetic study;
Rapid determination of 3â², 4â²-dimethoxy flavonol-3-β-d-glucopyranoside in rat plasma by LC-MS/MS method followed by protein precipitation
Keywords: مطالعه فارماکوکینتیک; LC-MS/MS; liquid chromatography/tandem mass spectrometry; LLOQ; lower limit of quantification; IS; internal standard; QC; quality control; DF3G; 3â²,4â²-dimethoxy flavonol-3-β-d-glucopyranoside; HPLC; high performance liquid chromatography; SD; standar
Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents
Keywords: مطالعه فارماکوکینتیک; Flavonol; Prostate cancer; Structure-activity relationship; Pharmacokinetic study; Cell apoptosis;
Short communicationDevelopment of a sensitive LC-MS/MS method for quantification of coniferyl ferulate and its metabolite coniferyl alcohol in rat plasma: Application to a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Coniferyl ferulate; Coniferyl alcohol; LC-MS/MS; Pharmacokinetic study;
Development a validated highly sensitive LC-MS/MS method for simultaneous quantification of Ledipasvir, sofosbuvir and its major metabolite GS-331007 in human plasma: Application to a human pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; LC-MS/MS; Sofosbuvir; Ledipasvir; GS-331007; Human plasma; Pharmacokinetic study; Hepatitis C;
Comparatively evaluating the pharmacokinetic of fifteen constituents in normal and blood deficiency rats after oral administration of Xin-Sheng-Hua Granule by UPLC-MS/MS
Keywords: مطالعه فارماکوکینتیک; Xin-Sheng-Hua Granule; Multi-constituents; Pharmacokinetic study; UPLC-TQ-MS/MS; Blood deficiency;
Design and optimization of a novel implantation technology in contact lenses for the treatment of dry eye syndrome: In vitro and in vivo evaluation
Keywords: مطالعه فارماکوکینتیک; Hyaluronic acid; Contact lenses; Implantation; Optimization; Pharmacokinetic study; In vivo efficacy study;
Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; CXCR4; Amide-sulfamide; Inflammation; Structure-activity relationship; Pharmacokinetic study; KBWXKIUGGGUTOE-UHFFFAOYSA-N;
Sensitive Analysis and Pharmacokinetic Study of Berberrubine Using LC-MS/MS
Keywords: مطالعه فارماکوکینتیک; berberrubine; berberrubine glucuronide; LC-MS/MS; pharmacokinetic study; rat biological samples;
Determination of AZD3759 in rat plasma and brain tissue by LC-MS/MS and its application in pharmacokinetic and brain distribution studies
Keywords: مطالعه فارماکوکینتیک; AZD3759; Epidermal growth factor receptor tyrosine kinase inhibitor; Pharmacokinetic study; Brain distribution; Rat;
Enhanced LC-MS/MS determination of alogliptin and metformin in plasma: Application to a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Alogliptin; Metformin; Tandem mass; Pharmacokinetic study; Egyptian African volunteers;
Synthesis, anticancer evaluation and pharmacokinetic study of novel 10-O-phenyl ethers of dihydroartemisinin
Keywords: مطالعه فارماکوکینتیک; 10-O-phenyl ethers of dihydroartemisinin; Anticancer activity; Multidrug resistance; G0/G1 phase cell cycle arrest; Pharmacokinetic study;
Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: Antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies
Keywords: مطالعه فارماکوکینتیک; 1,5-Diheteroarylpenta-1,4-dien-3-one; Prostate cancer; Cell proliferation; Pharmacokinetic study; Cell apoptosis;
Simultaneous quantification of picfeltarraenins IA and IB in rat plasma by UPLC–MS/MS: Application to a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Picfeltarraenins; Triterpenoid saponins; UPLC–MS/MS; Pharmacokinetic study
Determination of a potential antitumor quassinoid in rat plasma by UPLC–MS/MS and its application in a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Brusatol; Quassinoid; Rat plasma; UPLC–MS/MS; Pharmacokinetic study
Pharmacokinetic analysis of levo-tetrahydropalmatine in rabbit plasma by rapid sample preparation and liquid chromatography–tandem mass spectrometry
Keywords: مطالعه فارماکوکینتیک; Levo-tetrahydropalmatine; l-THP; Liquid chromatography; –tandem mass spectrometry; LC–MS/MS; Self-microemulsifying drug delivery system; Pharmacokinetic study
An improvement of separation and response applying post-column compensation and one-step acetone protein precipitation for the determination of coenzyme Q10 in rat plasma by SFC-MS/MS
Keywords: مطالعه فارماکوکینتیک; Coenzyme Q10; Post-column compensation; SFC-ESI–MS/MS; Pharmacokinetic study; Rat plasma
Pharmacokinetic profiles of falcarindiol and oplopandiol in rats after oral administration of polyynes extract of Oplopanax elatus
Keywords: مطالعه فارماکوکینتیک; Oplopanax elatus; Polyynes; LC-MS; Pharmacokinetic study;
Enhanced oral delivery of celecoxib via the development of a supersaturable amorphous formulation utilising mesoporous silica and co-loaded HPMCAS
Keywords: مطالعه فارماکوکینتیک; Amorphous formulation; Pharmacokinetic study; Mesoporous material; In vitro pH shift assay
Development and validation of a highly sensitive LC–MS/MS-ESI method for quantification of IIIM-019—A novel nitroimidazole derivative with promising action against Tuberculosis: Application to drug development
Keywords: مطالعه فارماکوکینتیک; IIIM-019; Nitroimidazole; LC–MS/MS; Pharmacokinetic study; Microsomal stability
Simultaneous determination of loganin, morroniside, catalpol and acteoside in normal and chronic kidney disease rat plasma by UPLC–MS for investigating the pharmacokinetics of Rehmannia glutinosa and Cornus officinalis Sieb drug pair extract
Keywords: مطالعه فارماکوکینتیک; UPLC–MS; Loganin; Morroniside; Catalpol; Acteoside; Chronic kidney disease; Rehmannia glutinosa; Cornus officinalis; Pharmacokinetic study
An improved LC–MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5-hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study
Keywords: مطالعه فارماکوکینتیک; Pyrazinamide; Pyrazinoic acid; 5-hydroxy pyrazinoic acid; LC–MS/MS; Human plasma; Pharmacokinetic study
Bioanalysis of dried saliva spot (DSS) samples using detergent-assisted sample extraction with UHPLC-MS/MS detection
Keywords: مطالعه فارماکوکینتیک; Dried saliva spot (DSS); Detergent-assisted sample extraction; Ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS); BMS-927711; Quantitation; Pharmacokinetic study