دانلود مقالات ISI درباره Pi-3K + ترجمه فارسی

چهره یانوس از فعال سازی نوتروفیل تحت کنترل مکمل در طی سپسیس

Janus face of complement-driven neutrophil activation during sepsis

Keywords: C3aR; C3a receptor; C5aR1/2; C5a receptor 1/2; CLP; cecal ligation and puncture; CXCR4; C-X-C chemokine receptor type 4; DAMPs/PAMPs; damage-/pathogen-associated molecular patterns; Efb; extracellular fibrinogen-binding protein; ERK; extracellular signal-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

جلوگیری از آسیب تابشی توسط محصولات طبیعی

Prevention from radiation damage by natural products

Keywords: Cancer; Phytochemical; Radiotherapy; Radioprotection; Side effects; AP-1; activator protein-1; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CAPE; caffeic acid phenylethylester; CAT; chloramphenicol acetyltransferase; CBMN; cytokinesis block

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

مقاله پژوهشیکارامازپین باعث بازسازی و زنده ماندن کبد در موش می شود

Research ArticleCarbamazepine promotes liver regeneration and survival in mice

Keywords: CBZ; carbamazepine; PHx; partial hepatectomy; PI-3K; phosphotidylinositol-3 kinase; MAPK; ras-mitogen-activated protein kinase; ERK; extracellular signal regulated kinase; DMSO; dimethyl sulfoxide; H&E; haematoxylin and eosin; IHC; immunohistochemistry; R

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

عوامل و مکانیسم های عضله اسکلتی در بیماری مزمن انسدادی ریه

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Keywords: 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Mesenchymal stem cells drive paclitaxel resistance in ErbB2/ErbB3-coexpressing breast cancer cells via paracrine of neuregulin 1

Keywords: Mesenchymal stem cells (MSCs); Paclitaxel-resistance; ErbB2/ErbB3-coexpressing breast cancer; Tumor microenvironment; hUC-MSCs; Human umbilical cord mesenchymal stem cells; NRG-1; neuregulin 1; PI-3K; phosphoinositide 3-kinase; qRT-PCR; real-time quantita

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer

Keywords: HER3; Survivin; miRNA; Paclitaxel resistance; Breast cancer; RTKs; Receptor tyrosine kinases; PI-3K; Phosphoinositide 3-kinase; CHX; Cycloheximide; ELISA; Enzyme-linked immunosorbent assay; IHC; Immunohistochemistry; i.p.; Intraperitoneal;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2

Keywords: Exendin-4; Pancreas; Impaired autophagy; Apoptosis; Ex-4; Exendin-4; GLP-1; glucagon-like peptide 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide; LC3B; light chain 3B; LAMP-2; lysosome associated membrance protein; CatB/L; cathepsin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Understanding the biology of HER3 receptor as a therapeutic target in human cancer

Keywords: Ab; antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FDA; Food and Drug Administration; HER; Human epidermal growth factor receptor; HRG; heregulin; IGF-1R; insu

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers

Keywords: ARTN; artemin; AS; activation segment; CD; cadherin-like domain; CDK; cyclin-dependent protein kinase; CL; catalytic loop; CS or C-spine; catalytic spine; CTT; carboxyterminal tail; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor re

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

A phosphoproteomic study reveals shp-1 cleavage reprograms LPS signaling via a PI-3K/NF-κB and mTORC1 related mechanism

Keywords: Shp-1; PI-3K; mTORC1; MODS; Phosphoproteome;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Keywords: Coumarins; Anticancer; Synthesis; Targets; SAR; IC50; ARI; aromatase inhibitor; CAM; choriallanotoic membrane; CDC; cell cycle division protein; CDK2; cyclin dependent kinase 2; CDKN1A; cyclin-dependent kinase inhibitor 1A; CYP; cytochromes P450; DDIT4; D

دانلود رایگان متن کامل مقاله ISI 72 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of chondrogenesis by protein kinase C: Emerging new roles in calcium signalling

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ADSC; adipose-derived stem cell; ATP; adenosine triphosphate; BMP; bone morphogenic protein; cAMP; cyclic adenosine monophosphate; COMP; cartilage oligomeric matrix protein; CREB; cAM

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Combination of bendamustine and entinostat synergistically inhibits proliferation of multiple myeloma cells via induction of apoptosis and DNA damage response

Keywords: MM; Multiple myeloma; CLL; chronic lymphocytic leukemia; HDAC; histone deacetylase; HDACi; Inhibitor of HDAC; HAT; Histone acetyltransferase; PARP; poly(ADP-ribose) polymerase; ELISA; enzyme-linked immunosorbent assay; PAGE; polyacrylamide gel electrophor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection

Keywords: GPCR; G protein-coupled receptors; GRK; G protein-coupled receptor kinase; LAM; lipoarabinomannan; PI-3K; phosphoinositide 3-kinases; ERK; extracellular signal-regulated kinase; Akt; serine/threonine protein kinase; COPD; chronic obstructive pulmonary dis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Absence of pyruvate anti-oxidant effect on granulocytes stimulated toll-like receptors

Keywords: Type 2 diabetes; Pyruvate; ROS; TLR4; Granulocytes; AGEs; advanced glycation end products; Con A; concanavalin A; DAG; diacylglycerol; DMEM; Dulbecco's modified Eagle's medium; GSH; glutathione; GSH-Et; glutathione ethyl ester; HMGB-1; high-mobility g

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Viridin analogs derived from steroidal building blocks

Keywords: PI-3K; Wortmannin; Viridin; Steroid; Irreversible enzyme inhibitors;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Oxidative stress and diabetes: What can we learn about insulin resistance from antioxidant mutant mouse models?

Keywords: 4HNE; 4-hydroxynonenal; 8-OHdG; 8-hydroxyguanosine; AGE; advanced glucation end-product; Akt/PKB; protein kinase B; Cat; catalase, CuZnSod; Sod1; copper/zinc superoxide dismutase, ECSod; Sod3; extracellular superoxide dismutase; ETC; electron transport ch

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status

Keywords: Apaf-1; apoptosis-protease activating factor-1; BH; Bcl-2 homology domain; CREB; cAMP response element-binding protein; Ct; cycle threshold; GPX1; glutathione peroxidise-1; H2O2; hydrogen peroxide; IAP; inhibitor of apoptosis protein; IFN-γ; interferon-Î

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Multi-mechanisms are involved in reactive oxygen species regulation of mTORC1 signaling

Keywords: AMPK; AMP-activated protein kinase; CHAPS; 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonic acid; 2,7-DCFH-DA; 2,7 Dichlorodihydrofluorescein diacetate; DTT; dithiothreito; EGFR; epidermal growth factor receptor; MDA; malondialdehyde; mSin1; mamm

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior

Keywords: GluR1; GluR2; Carrageenan; Rat; PI-3K; TNF;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Cationic lipids activate cellular cascades. Which receptors are involved?

Keywords: AP-1; activator protein 1; CD 14/80/86; cluster of differentiation 14/80/86; diC14-amidine; N-t-butyl-N′-tetradecyl-3-tetradecylaminopropionamidine; DAG; diacylglycerol; DMPC; dimyristoyl-phosphatidylcholine; DMPG; dimyristoyl-phosphatidylglycerol; DMKD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Up-regulation of IAPs by PI-3K: A cell survival signal-mediated anti-apoptotic mechanism

Keywords: TRAIL; IAP; PI-3K; Akt; PTEN; LNCaP cells; Caspase-3; Apoptosis; Cell survival signal

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Exogenous application of persephin influences phosphatidylinositol-3 kinase and MAPK/ERK signalling and enhances proliferation during early development in retinospheres

Keywords: Persephin; Glial cell line-derived neurotrophic factor; Retina; PI-3K; MAPK; Proliferation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Proteasome inhibitors induce osteoclast survival by activating the Akt pathway

Keywords: Osteoclast; Apoptosis; MG132; ALLN; PI-3K

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Amitriptyline induces nuclear transcription factor-κB-dependent glutamate transporter upregulation in chronic morphine-infused rats

Keywords: amitriptyline; nuclear transcription factor-kB; glutamate transporters; excitatory amino acids; microdialysis; morphine tolerance; CSF; cerebrospinal fluid; EAAC1; excitatory amino acid carrier 1; GLAST; glutamate-aspartate transporter; GLT-1; glutamate t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Development of a pharmacologically improved peptide agonist of the leptin receptor

Keywords: Ab; antibody; ANOVA; analysis of variance; ATCC; American Type Culture Collection; BBB; blood-brain barrier; BSA; bovine serum albumin; CNS; central nervous system; CRH; cytokine receptor homology; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium

Keywords: Fibronectin; MMP-2; MMP-9; MT1-MMP; NF-κB; ERK; PI-3K

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells

Keywords: Epigallocatechin gallate; Ephrin-A1; EphA2; PI-3K; ERK-1/2; Cell migration; Angiogenesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

NGF-dependent formation of ruffles in PC12D cells required a different pathway from that for neurite outgrowth

Keywords: NGF; PC12D; Ruffle; Rac1; Ras; PI-3k; GSK-3β; Neurite

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Stromal cell derived factor-1 acutely promotes neural progenitor cell proliferation in vitro by a mechanism involving the ERK1/2 and PI-3K signal pathways

Keywords: Neural progenitor cells (NPCs); SDF-1; Proliferation; ERK1/2; PI-3K;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

α2-Adrenergic receptor subtype-specific activation of NF-κB in PC12 cells

Keywords: α2-ARs; α2-adrenergic receptors; GPCR; G-protein coupled receptor; CNS; central nervous system; KO; knock-out; MAPK; mitogen-activated protein kinase; AP-1; activator protein-1; NF-κB; nuclear factor-kappaB; PI-3K; phosphatidyl inositol-3′OH kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation

Keywords: PI-3K; Akt; PTEN; FAK; Src; Anoikis; Osteosarcoma;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Amphiregulin: An early trigger of liver regeneration in mice

Keywords: AR; amphiregulin; BrdU; 5-bromo-2′-deoxyuridine; CRE; cyclic adenosine monophosphate-responsive element; EGF; epidermal growth factor; EGF-R; epidermal growth factor receptor; ERK; extracellular regulated kinase; FCS; fetal calf serum; HB-EGF; heparin-b

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Adaptive evolution of the human fatty acid synthase gene: Support for the cancer selection and fat utilization hypotheses?

Keywords: FAS; Fatty acid Synthase; NADPH; Nicotinamide adenine dinucleotide phosphatase; PTEN; Phosphatase and tensin homolog; MAP(K1); Mitogen-activated protein (kinase 1); PI-3K; Phosphatidylinositol-3 kinase; SREBP; Sterol regulatory Element binding Proteins; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Effects on the serotoninergic system in sub-acute transmissible spongiform encephalopathies: current data, hypotheses, suggestions for experimentation

Keywords: TSEs; sub-acute transmissible spongiform encephalopathies; PrP; prion protein; PrPC; normal protease-sensitive PrP; PrPres; abnormal protease-resistant PrP; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; TRP; tryptophan; BSP; bovine spastic paresis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Pathogénie des vascularites systémiques primitives (I) : vascularites ANCA-positives

Keywords: Ac; anticorps; Akt; sérine/thréonine kinase (ou protein kinase B); α1-AT; α 1-antitrypsine; ANCA; Ac anti-cytoplasme de polynucléaire neutrophile; CE; cellule endothéliale; ELAM-1; endothelial-leucocyte adhesion molecule-1; ERK; extracellular signal

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2?

Keywords: Development and regeneration; Neuronal death; Ara-C; Cytosine arabinoside; BSA; Bovine serum albumin; CaMKIV; Calcium-calmoduline kinase IV; CAPP; Ceramide activated protein phosphatase; cer: c2-ceramide; CREB; CAMP-response element binding protein; ECLEn

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen

Keywords: AEC; aortic endothelial cell; bFGF; basic fibroblast growth factor; cAMP; cyclic adenosine 3′,5′-monophosphate; CKI; cyclin-dependent kinase inhibitor; CRY1; cryptochrome 1; CYP3A6; cytochrome p450 oxidase 3A6; DEC1; deleted in esophageal cancer 1; 4E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Facilitation of conditioned fear extinction by d-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala

Keywords: extinction; D-cycloserine; MAPK; PI-3 kinase; amygdala; ACT+DCS; actinomycin D+d-cycloserine; ACT+SAL; actinomycin D+saline; ANI+DCS; anisomycin+d-cycloserine; ANI+SAL; anisomycin+saline; BLA; basolateral nucleus of the amygdala; CS; conditioned stimulus;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Insulin neuroprotection against oxidative stress in cortical neurons-Involvement of uric acid and glutathione antioxidant defenses

Keywords: BSA; bovine serum albumin; t-BHP; tert-butylhydroperoxide; CNS; central nervous system; ERK; extracellular signal-related kinase; DNPH; 2,4-dinitrophenylhydrazine; DTT; 1,4-dithiotreitol; GLUT; glucose transporter; GPx; glutathione peroxidase; GRed; gluta

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه