دانلود مقالات ISI PI3K: 2262 مقاله انگلیسی + ترجمه فارسی

PI3K

در این صفحه تعداد 2262 مقاله تخصصی درباره که در نشریه های معتبر علمی و پایگاه ساینس دایرکت (Science Direct) منتشر شده، نمایش داده شده است. برخی از این مقالات، پیش تر به زبان فارسی ترجمه شده اند که با مراجعه به هر یک از آنها، می توانید متن کامل مقاله انگلیسی همراه با ترجمه فارسی آن را دریافت فرمایید.
در صورتی که مقاله مورد نظر شما هنوز به فارسی ترجمه نشده باشد، مترجمان با تجربه ما آمادگی دارند آن را در اسرع وقت برای شما ترجمه نمایند.

مقالات ISI (ترجمه نشده)

مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.

PI3K/SGK1/GSK3Î² signaling pathway is involved in inhibition of autophagy in neonatal rat cardiomyocytes exposed to hypoxia/reoxygenation by hydrogen sulfide

Keywords: H2S; Autophagy; Cardiomyocyte; Hypoxia/reoxygenation; PI3K; SGK1; GSK3Î²;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Induced cortical neurogenesis after focal cerebral ischemia - Three active components from Huang-Lian-Jie-Du Decoction

Keywords: HLJDD; Huang-Lian-Jie-Du-Decoction; BrdU; 5-bromodeoxyuridine; TCM; Traditional Chinese Medicine; pMACO; permanent middle cerebral artery occlusion; CNS; Central Nervous System; VEGF; Vascular Endothelial Growth Factor; Ang; Angiopoietin; qRT-PCR; quantit

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and Î²-TrCP

Keywords: Nrf2; Keap1; GSK-3; PKB/Akt; PI3K; PTEN; Î²-TrCP; ARE; antioxidant response element; tBHQ; tert-butyl hydroquinone; bZIP; basic-region leucine zipper; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; CNC; cap'n'collar; Cul1; cullin-1; Cu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma

Keywords: Combination therapy; EGFR; KRAS; PI3K; PIK3CA;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner

Keywords: HIF; Hypoxia-inducible Factor; IL-6; Interleukin 6; IRS1; Insulin Receptor Substrate 1; Jak; Januskinase; mTOR; Mammalian Target of Rapamycin; MEF; Mouse Embryonic Fibroblast; NF-ÎºB; Nuclear Factor kappa B; n.s.; non-significant; MAPK; Mitogen-Activated

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves

Keywords: IL-31; IL-31 receptor Î±; dorsal root ganglia; atopic dermatitis; nerve growth; cutaneous hyperinnervation; AD; Atopic dermatitis; DRG; Dorsal root ganglia; ERK; Extracellular signal-regulated kinase; IL-31RA; IL-31 receptor Î±; IPA; Ingenuity pathway ana

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation

Keywords: Akt; PI3K; mTORC1; Signalling; Axon establishment; Polarity;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway

Keywords: CuE; Cucurbitacin E; ECM; extracellular matrix; HSCs; Hepatic stellate cells; TNF-Î±; tumor necrosis factor-Î±; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PARP; poly ADP-ribose polymerase; MAPK; mitogen activated protein kinase; ER

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular characterization and functional analysis of BdFoxO gene in the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae)

Keywords: TOR; target of rapamycin; JNK; Jun NH2-terminal kinase; FoxO; forkhead box O; InR; insulin receptor; Akt; protein kinase B; PI3K; phosphatidylinositol 3-kinase; 4EBP; 4E binding protein; ILPs; insulin-like peptides; RT-qPCR; reverse transcription-quantita

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

The role of CD36 in the regulation of myocardial lipid metabolism

Keywords: ACSL; acyl-coenzyme A synthetase; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ATGL; adipose triglyceride lipase; CPT; carnitine palmitoyltransferase; CVD; cardiovascular disease; FAT (CD36); fatty acid tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; Î²-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the TGF-Î² pathway by deubiquitinases in cancer

Keywords: AMSH; Associated molecule with SH3 domain proteases; AMSH-LP; Associated molecule with SH3 domain-like proteases; ATXN3; ataxin-3; ATXN3L; ataxin 3-like; BMPs; bone morphogenetic proteins; BRCC36; BRCA1/BRCA2-containing complex subunit 36; CHIP; carboxy t

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Insulin-like growth factor 1 (IGF-1) therapy: Mitochondrial dysfunction and diseases

Keywords: ÎÎ¨m; membrane potential; AD; Alzheimer's disease; AMPK; adenosine-monophosphate-activated kinase; ATG proteins; autophagy-related proteins; ATP; adenosine triphosphate; CaMKs; calcium-calmodulin-activated kinases; CDKs; cyclin-dependent kinases; CNS;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological postconditioning against myocardial infarction with a slow-releasing hydrogen sulfide donor, GYY4137

Keywords: GYY4137-Morphilino salt (PubChem CID: 469337261); LY294002 (PubChem CID: 3973); N-Nitro-l-arginine methyl ester hydrochloride (PubChem: 39836); AAR; area at risk; Akt; protein kinase B; DATS; diallyltrisulfide; eNOS; endothelial nitric oxide synthase; ERK

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb)

Keywords: As; arsenic; FGF-2; basic fibroblast growth factor; BMP-2; bone morphogenetic protein-2; Ce; cerium; COX; cyclooxygenase; EC; endothelial cells; EPCR; endothelial cell protein C receptor; EPCs; endothelial progenitor cells; EMT; epithelial to mesenchymal

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca2Â + signaling

Keywords: a.a.; amino acid; ATP; adenosine triphosphate; BH domain; Bcl-2-homology domain; BI-1; Bax inhibitor-1; BIRD-2; Bcl-2/IP3R disruptor-2; BRCA1; breast and ovarian cancer susceptibility gene 1; [Ca2Â +]cyt; cytosolic Ca2Â + concentration; CLL; chronic lymph

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells ViaÂ CD63 Signaling to Create a Premetastatic Niche in the Liver

Keywords: Tissue Inhibitor of Metalloproteinases; Tumor Progression; Signal Transduction; Microenvironment; CP; chronic pancreatitis; HSC; hepatic stellate cell; PanIN; pancreatic intra-epithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PDGF-B; platelet-

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1Î±

Keywords: Akt; protein kinase B; AMPK; AMP-activated protein kinase; AVOs; acidic vesicular organelles; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BNIP3L; BCL2/adenovirus E1B 19Â kDa interacting protein 3-like; CCND1; cyclin D1; CFSE; 5-(6)-carboxyfl

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis

Keywords: 2-AG; 2-arachidonoylglycerol; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; hypothalamic arcuate nucleus; CRH; corticotropin-releasing hormone; DSI; depolarization-induced suppression of inhibition; ERK; extracellular signal-regul

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events

Keywords: CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAK; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; SHC; Src homolog

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Nutrient restriction of glucose or serum results in similar proteomic expression changes in 3D colon cancer cell cultures

Keywords: Nutrient restriction; Three dimensional cell culture; Autophagy; Apoptosis; Quantitative proteomics; Colorectal cancer; NR; nutrient restriction; FBS; fetal bovine serum; iTRAQ; isobaric tags for relative and absolute quantification; SIRT1; sirtuin 1; PIA

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment

Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines

Keywords: Suzuki coupling synthesis of 8- and 6-aryl-2-morpholino-1,3-benzoxazines; DNA-PK; PI3K; Anti-cancer activity;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair targeted therapy: The past or future of cancer treatment?

Keywords: DNA damage; DNA repair; Cancer; Radiation; Replication protein A; NER; nucleotide excision repair; MMR; DNA mismatch repair; BER; base excision repair; HDR; homology directed repair; FA; Fanconi anemia; HR; homologous recombination; DDR; DNA damage respon

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

Keywords: Spleen Tyrosine Kinase; DNA Methylation; Tumor Suppressor; Inflammatory Homeostasis; CES; composite expression score; CLEC2; C-type lectin-like receptor 2; EMT; epithelial to mesenchymal transition; GSK3; glycogen synthase kinase 3; IHC; immunohistochemis

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2016 سفارش ترجمه

ROS/oxidative stress signaling in osteoarthritis

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ATF/CRE; activating transcription factor/cyclic AMP-response element; ATF-2; activating transcription factor 2; Bach 1; broad complex-tramtrack-bric-a-brac (BTB) and cap'n'collar (CNC

دانلود رایگان متن کامل مقاله ISI 99 صفحه سال انتشار : 2016 سفارش ترجمه

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

Keywords: AC; adenylyl cyclase; AI; anemia of inflammation; cdks; cyclin-dependent kinases; bFGF; basic fibroblast growth factor; BpT; 2-benzoylpyridine thiosemicarbazone; Bp4eT; 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone; Bp44mT; 2-benzoylpyridine 4,4-dimethyl-

دانلود رایگان متن کامل مقاله ISI 103 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of mutations in Wnt/Î²-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

Keywords: GSK-3; Wnt/beta-catenin; PI3K; Akt; mTOR; Hedgehog; Notch; Targeted therapy; Therapy resistance;

دانلود رایگان متن کامل مقاله ISI 158 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological targeting of PI3K isoforms as a therapeutic strategy in chronic lymphocytic leukaemia

Keywords: CLL; PI3K; Idelalisib; Duvelisib

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-inflammatory effects of farrerol on IL-1β-stimulated human osteoarthritis chondrocytes

Keywords: Farrerol; Osteoarthritis chondrocyte; IL-1β; NF-κB; PI3K

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy machinery in the context of mammalian mitophagy

Keywords: PINK1; PTEN-induced putative kinase 1; CCCP; carbonyl cyanide m-chlorophenylhydrazone; OMM; outer mitochondrial membrane; ATG; autophagy-related; ULK1; unc-51 like kinase 1; FIP200; focal adhesion kinase family interacting protein of 200Â kDa; mTor; mecha

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

IGFBP-2/PTEN: A critical interaction for tumours and for general physiology?

Keywords: IGFBP-2; PTEN; PI3K; IGF-II; Feedback

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Thymoquinone inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells

Keywords: Thymoquinone; LPS; NF-κB; PI3K; Microglia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

The glucosylceramide synthase inhibitor PDMP sensitizes pancreatic cancer cells to MEK/ERK inhibitor AZD-6244

Keywords: MTT; 3-[4,5-dimethylthylthiazol-2-yl]-2,5 diphenyltetrazolium bromide; PDMP; d,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; mTOR; mammalian target of rapamycin; MAPK; mitogen activat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The protective effect of GLP-1 analogue in arterial calcification through attenuating osteoblastic differentiation of human VSMCs

Keywords: Vascular smooth muscle cells; Calcification; Osteoblastic differentiation; Glucagon-like peptide-1; siRNA; PI3K; Akt; mTOR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo

Keywords: SEMA4B; Non-small cell lung cancer (NSCLC); PI3K; FoxO1; P21;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Echinacea purpurea root extract inhibits TNF release in response to Pam3Csk4 in a phosphatidylinositol-3-kinase dependent manner

Keywords: Akt; Echinacea; Polysaccharide; Pam3Csk4; PI3K; THP-1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions

Keywords: Autophagy; PANC-1; Extreme nutrient deprivation; Apoptosis; Survival; AMPK; 5â² adenosine monophosphate-activated protein kinase; CQ; chloroquine; LC3; microtubule-associated protein 1A/1B-light chain 3; mTOR; mammalian target of rapamycin; PDAC; pancrea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKÎ²

Keywords: 4E-BP1; eukaryotic translation initiation factor 4E-binding protein; BMDM; bone marrow-derived macrophage; CM; conditioned medium; DMEM; Dulbecco's modified essential medium; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?

Keywords: AP; activator protein; APAF; apoptosis protease activating factor; CAD; caspase-activated DNase; CHO; Chinese hamster ovary; CIA; collagen-induced arthritis; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DR; death r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Clinical and Genetic Aspects of the Segmental Overgrowth Spectrum DueÂ to Somatic Mutations in PIK3CA

Keywords: CLOVES; Congenital lipomatous overgrowth with vascular, epidermal, and skeletal anomalies; ddPCR; Droplet digital polymerase chain reaction; FFPE; Formalin-fixed and paraffin-embedded; KTS; Klippel-Trénaunay syndrome; LM; Lymphatic malformation; MCAP; Me

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A randomized, phase 2 trial of docetaxel with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer

Keywords: PIK3CA; PI3K; Docetaxel; Head and neck squamous cell cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Schisandrin B suppresses glioma cell metastasis mediated by inhibition of mTOR/MMP-9 signal pathway

Keywords: Akt; mTOR; Cell invasion; Cell migration; PI3K

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Sphingosine 1-phosphate induced synthesis of glycocalyx on endothelial cells

Keywords: Sphingosine 1-phosphate; Glycocalyx; PI3K

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Differential regulation of Connexin50 and Connexin46 by PI3K signaling

Keywords: Connexin; Lens; Gap junction; PI3K; Akt