دانلود مقالات ISI درباره Pi3K + ترجمه فارسی

Old and new generation lipid mediators in acute inflammation and resolution

Keywords: 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling

Keywords: ROS; reactive oxygen species; Nox; NADPH oxidase; O2•−; superoxide; RNS; reactive nitrogen species; •NO; nitric oxide; SOD; superoxide dismutase; NOS; nitric oxide synthase; GSH; glutathione; AngII; angiotensin II; PDGF; platelet-derived growth fact

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice

Keywords: Neoplasia; Colon Cancer; Drug Resistance; Tumor Resistance to Chemotherapy; AKT/PKB; AKT/protein kinase B; ALDH; aldehyde dehydrogenase; APC; adenomatous polyposis coli; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; CR; color

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Relationship of electrophilic stress to aging

Keywords: 4-HNE; 4-hydroxynon-2-enal; GST; glutathione transferase; Hsp; heat shock protein; I/R; ischemia/reperfusion; IIS; insulin/insulin-like signaling; MUFA; monounsaturated fatty acid; PI3K; phosphatidylinositol 3-kinase; PUFA; polyunsaturated fatty acid; RNA

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer

Keywords: PLC-γ; PI3K; PTEN; SHC; GRB2; RAS; STAT; IGFR; c-MET

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Mutant Kras Promotes Hyperplasia and Alters Differentiation in the Colon Epithelium but Does Not Expand the Presumptive Stem Cell Pool

Keywords: Colon Cancer; Oncogene; Tumor Suppressor; Transgenic Mice; Cdk; cyclin-dependent kinase; CRC; colorectal cancer; EGFP; enhanced green fluorescent protein; ERK; extracellular signal-regulated kinase; EYFP; enhanced yellow fluorescent protein; HPP; hyperpla

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2011 سفارش ترجمه

Energy metabolism in adult neural stem cell fate

Keywords: ACC; adenylate cyclase complex; AICAR; aminoimidazole carboxamide ribonucleotide; AMPK; AMP-activated protein kinase; Aspm; abnormal spindle-like microcephaly-associated; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; bHLH;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2011 سفارش ترجمه

CD151 Amplifies Signaling by Integrin α6β1 to PI3K and Induces the Epithelial-Mesenchymal Transition in HCC Cells

Keywords: Liver Cancer; Tumor Progression; Metastasis; Tumor Invasion; α-SMA; α-smooth muscle actin; Akt; protein kinase B; EMT; epithelial-mesenchymal transition; ERK; extracellular regulated protein kinase; GSK-3; glycogen synthase kinase 3; Ln-5; Laminin 5; MA

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2011 سفارش ترجمه

Increased expression of Akt2 and activity of PI3K and cell proliferation with the ascending of tumor grade of human gliomas

Keywords: Gliomas; Akt2; PI3K; Cell proliferation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

4-Methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors

Keywords: PI3K; mTOR; Kinase inhibitor; Cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3Kα

Keywords: mTOR; PI3K; Kinase inhibitors; Cancer; Oncology

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitors

Keywords: mTOR; PI3K; Kinase; Inhibitor; Cancer; Oncology; Antiproliferative

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor

Keywords: PI3K; mTOR; Kinase inhibitors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles

Keywords: PTEN; Phosphatase; PI3K; Tau; Neurofibrillary tangles; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

IL-13 promotes the proliferation of rat pancreatic stellate cells through the suppression of NF-κB/TGF-β1 pathway

Keywords: Pancreatic stellate cell (PSC); Interleukin-13; Chronic pancreatitis; Fibrosis; Proliferation; α-SMA; α-smooth muscle actin; ELISA; enzyme-linked immunosorbent assay; HRP; Horseradish peroxidase; HSC; hepatic stellate cell; Ig; immunoglobulin; IL; inter

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways

Keywords: Akt; phosphatidylinosoltol regulated protein kinase; IGF-I; insulin-like growth factor-I; IOD; integrated optical densities; IRS-1; insulin related substrate-1; MKR; IGF-I receptor mutant mouse; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinoso

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma

Keywords: Akt; Immunoresistance; PI3K; PTEN tumor suppressor gene

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K

Keywords: mTOR; PI3K; Cancer; Oncology; Kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Keywords: mTOR; PI3K; Cancer; Serine/threonine kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Differential modulation of a radiation-induced bystander effect in glioblastoma cells by pifithrin-α and wortmannin

Keywords: Microbeam irradiation; Glioma cells; Nitric oxide; p53; PI3K

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Role and regulation of PI3K in sperm capacitation and the acrosome reaction

Keywords: Spermatozoa; Capacitation; Acrosome reaction; PI3K; PKA; PKC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Methylation, a key step for nongenomic estrogen signaling in breast tumors

Keywords: ERα; Src; PI3K; FAK; PRMT1; Breast cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras–Raf and PI3K–Akt signaling pathways

Keywords: Polygonatum cyrtonema lectin (PCL); Apoptosis; Autophagy; Ras; PI3K

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Modulation of μ-opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase γ

Keywords: MOR; PI3Kγ; DRG; VGCC; desensitization; opioid tolerance; DAMGO; D-Ala2,N-Me-Phe4,Gly5-ol-enkephalin; DRG; dorsal root ganglion; GPCR; G protein-coupled receptor; MOR; μ-opioid receptor; PI3K; phosphoinositide 3-kinase, class 1; TRPV1; transient recepto

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

GTPase activating protein function of p85 facilitates uptake and recycling of the β1 integrin

Keywords: Phosphoinositide 3-kinase; p85; Staphylococcus aureus; Statins; Breakpoint cluster region; GTPases; small-guanosine triphosphatases; PI3K; phosphoinositide 3-kinase; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; GAP; GTPase activating protein; BCR; brea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: Optimization of human microsomal stability

Keywords: mTOR; PI3K; Kinase inhibitors; Cancer; Oncology; Microsomes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Fine tuning T lymphocytes: A role for the lipid phosphatase SHIP-1

Keywords: T Lymphocyte; Lipid phosphatase; PI3K; Chemotaxis; miRNA; TReg;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Addiction to protein kinase CK2: A common denominator of diverse cancer cells?

Keywords: ALCL; anaplastic large cell lymphoma; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CML; chronic myeloid leukemia; MDR; multi-drug resistance; MM; multiple myeloma; NF-kB; nuclear factor-kB; PDK1; 3′-phosphoinositide-dependent kinase-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of survivin by PI3K/Akt/p70S6K1 pathway

Keywords: Survivin; PI3K; Akt; p70S6K1; siRNA; CEF

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Cyclophosphamide promotes cell survival via activation of intracellular signaling in cultured cortical neurons

Keywords: Cyclophosphamide; PI3K; ERK; Bcl2; Cell survival; Cell death

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR

Keywords: Neural stem cells; PI3K; mTOR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Spatiotemporal alteration in phosphatidylinositide 3-kinase–serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung

Keywords: PI3K; AKT; Nitrofen; Hypoplastic lung; Congenital diaphragmatic hernia

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Insulin temporal sensitivity and its signaling pathway in the rat pineal gland

Keywords: Pineal gland; Melatonin synthesis; Insulin action; Arylalkylamine-N-acetyltransferase (AANAT); PI3K

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular networks in respiratory epithelium carcinomas

Keywords: Respiratory epithelium carcinomas; EGFR; Ras; Raf; MAPK; PI3K; Akt; JAK; STAT; PLC; PKC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck

Keywords: mTOR; CCR7; PI3K; Squamous cell carcinoma of head and neck; Survival;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: Involvement of EGF receptor/PI3K/Akt signaling pathway

Keywords: Apoptosis; Akt; Ca9-22 cell; EGF receptor; PI3K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Targeting Endocrine Resistance: Is There a Role for mTOR Inhibition?

Keywords: Estrogen receptor; Mammalian target of rapamycin; Metastatic breast cancer; PI3K;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein

Keywords: Coronary artery bypass graft; IGF-1; Internal mammary artery; Intimal hyperplasia; PI3K; Akt/PKB; Proliferation; Restenosis; Saphenous vein; Vascular smooth muscle cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Poly(I:C) induces BLyS-expression of airway fibroblasts through phosphatidylinositol 3-kinase

Keywords: BLyS; Fibroblast; Airway; dsRNA; PI3K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Impact of HDL on adipose tissue metabolism and adiponectin expression

Keywords: aP2; adipocyte lipid-binding protein; apo; apolipoprotein; C; cholesterol; CETP; cholesterol ester transfer protein; LPS; lipopolysaccharide; PI3K; phosphatidylinositol-3-kinase; TNF-α; tumor necrosis factor alpha; TLR; Toll like receptor; Apo A-I; Adipo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

CommentaryModulation of cell sensitivity to antitumor agents by targeting survival pathways

Keywords: AMPK; AMP-dependent protein kinase; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinases; GRP78; glucose-regulated protein 78; HDAC; histone deacetylase; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; PI3K;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticlePancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation

Keywords: PDX-1; Pancreatic Duodenal Homeobox-1; NRC; normal rat cultured cholangiocytes; BDL; bile duct ligation; cAMP; cyclic adenosine 3′,5′-monophosphate; FBS; fetal bovine serum; PKA; protein kinase A; PI3K; phosphatidyl-inositol-3-kinase; PCNA; proliferat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleSynergistic interactions between sorafenib and bortezomib in hepatocellular carcinoma involve PP2A-dependent Akt inactivation

Keywords: HCC; Sorafenib; Proteasome inhibitor; Akt; Apoptosis; PP2A; Molecular targeted therapy; HCC; hepatocellular carcinoma; HBV; hepatitis B virus; HCV; hepatitis C virus; PP2A; protein phosphatase 2A; PI3K; phosphatidylinositol-3-kinase; PDK1; phosphatidylino

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells

Keywords: CDKI; cyclin-dependent kinase inhibitor; I3C; indole-3-carbinol; PARP; poly (ADP-ribose) polymerase; PI3K; phosphatidylinositol 3-kinase; z-IETD-FMK; benzyloxycarbonyl-Ile-Glu (OMe)-Thr-Asp (OMe)-fluoromethyl ketone; Indole-3-carbinol; Lung cancer; A549;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanisms involved in phosphatidylinositol 3-kinase pathway mediated up-regulation of the mu opioid receptor in lymphocytes

Keywords: Morphine; Mu opioid receptor; PI3K; Signaling; Gene expression; Regulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Leukotriene B4 mediates vascular smooth muscle cell migration through αvβ3 integrin transactivation

Keywords: LTB4; SMC; FAK; PI3K; αvβ3 integrin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Tight Glycemic Control Protects the Myocardium and Reduces Inflammation in Neonatal Heart Surgery

Keywords: BG; blood glucose; BNP; brain-natriuretic peptide; CHS; congenital heart surgery; CIT; conventional insulin therapy; CO; cardiac output; CPB; cardiopulmonary bypass; CRP; C-reactive protein; cTnI; cardiac troponin-I; DSC; delayed sternal closure; d-TGA; t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Non-canonical functions of RGS proteins

Keywords: AC; adenylyl cyclase; CHO; Chinese hamster ovary; CNK1; connector enhancer of KSR1; CREB; cAMP-response element binding protein; DH; dbl-homology; DMAP1; Dnmt1-associated protein 1; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; ERK; ext

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The lipid-modulating effects of a CD4-specific recombinant antibody correlate with ZAP-70 segregation outside membrane rafts

Keywords: ADAP; adhesion- and degranulation-promoting adapter protein; Carma1; caspase-recruitment domain [CARD]-membrane-associated guanylate kinase [MAGUK] protein 1; CDR3; complementary determining region 3; GM1; ganglioside M1; GC; gas chromatography; HER2; hum

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of the PI3K–Akt pathway by human T cell leukemia virus type 1 (HTLV-1) oncoprotein Tax increases Bcl3 expression, which is associated with enhanced growth of HTLV-1-infected T cells

Keywords: HTLV-1; Bcl3; PI3K; AKT; Post-transcriptional mechanisms

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه