دانلود مقالات ISI درباره Pi3K + ترجمه فارسی

Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat

Keywords: DZ, diazoxide; MitoKATP, mitochondrial ATP-sensitive potassium; 5-HD, 5-hydroxydecanoic acid; WTN, wortmannin; PI3K, phosphatidylinositol-3-kinase; MDA, malondialdehyde; SOD, superoxide dismutase; CA3, cornu ammonis region 3Diazoxide; PI3K; Oxidative stre

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Mutational analysis of PTEN/PIK3CA/AKT pathway in oral squamous cell carcinoma

Keywords: Oral cancer; Head and neck cancer; Oral squamous cell carcinoma; PI3K; AKT; RAS; PTEN

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

P2 receptor stimulation induces amyloid precursor protein production and secretion in rat cortical astrocytes

Keywords: 2MeSADP; 2-methylthio-ADP; 8PSPT; 8-(p-sulfophenyl)-theophylline; AD; Alzheimer's disease; APP; amyloid precursor protein; BzATP; 3′-O-(4-benzoyl)benzoyl-ATP; DAPI; 4′-6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; ERK; extracel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Concanavalin A: A potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics

Keywords: BHA; butylated hydroxyanisole; BNIP3; adenovirus E1B 19 kDa-interacting protein 3; ConA; Concanavalin A; COX-2; cyclooxygenase-2; Cyto c; cytochrome c; DAPK; dual-specificity protein kinase; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activ

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors

Keywords: Oxatriazine scaffold; PI3K; mTOR; Akt; PKI-587; PKI-402

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of contractility and metabolic signaling by the β2-adrenergic receptor in rat ventricular muscle

Keywords: β2-adrenergic receptor; Cardiac contractility; Cardiac metabolism; AMPK; PI3K;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Research reportNMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways

Keywords: NMDA preconditioning; Signaling pathways; PI3K; PKA; Neuroprotection; Quinolinic acid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes

Keywords: ERK; extracellular signal-regulated kinase; GSK3β; glycogen synthase kinase-3β; I-κB-α; inhibitor of kappaB-alpha; IKKβ; IκB kinase β; iNOS; inducible nitric oxide synthase; IR; insulin receptor; IRS-1; insulin receptor substrate-1; JNK; c-Jun N-te

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Thyroid hormone differentially modulates Warburg phenotype in breast cancer cells

Keywords: T3; triiodothyronine; T4; thyroxine; 2NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diaxol-4-yl)amino]-2-deoxyglucose; DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; TMRM; tetramethyl rhodamine methyl ester; ROS; reactive

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Genes that integrate multiple adipogenic signaling pathways in human mesenchymal stem cells

Keywords: Functional genomics; Adipogenesis; Human mesenchymal stem cell; Gene screening; Multiple pathway communication; hMSCs; human mesenchymal stem cells; Dex; dexamethasone; IBMX; 3-isobutyl-1-methylxanthine; C/EBP; CCAAT/enhancer-binding protein; PPARγ; pero

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Perfluorooctane sulfonate triggers tight junction “opening” in brain endothelial cells via phosphatidylinositol 3-kinase

Keywords: Perfluorooctane sulfonate; Brain endothelial cells; Tight junction; PI3K; Blood-brain barrier;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes

Keywords: EETs, epoxyeicosatrienoic acids; PI3K, phosphatidylinositol 3-kinase; JNK, c-Jun N-terminal kinase; IRS-1, insulin receptor substrate-1; sEH, soluble epoxide hydrolaseInsulin resistance; Epoxyeicosatrienoic acids; Insulin signal; AKT; PI3K; JNK

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Hypoxia induces RANK and RANKL expression by activating HIF-1α in breast cancer cells

Keywords: RANK; receptor activator of NF-κB; RANKL; receptor activator of NF-κB ligand; OPG; osteoprotegerin; PI3K; the phosphoinositide 3-kinase; HIF; hypoxia-inducible factor; Hypoxia; RANK; RANKL; Migration; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori

Keywords: Bombyx mori; PTTH; Ecdysteroidogenesis; Prothoracic gland; PI3K; Akt; Signal transduction; Crosstalk

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor

Keywords: EGCG; (−)-epigallocatechin-3-gallate; PI3K; phosphoinositide-3-kinase; mTOR; mammalian target of rapamycin; PI(3,4,5)P3; phosphatidylinositol-3,4,5-triphosphate; ATP; adenosine 5′-triphosphate; mTORC2; mammalian target of rapamycin complex 2; FRAP1; F

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells

Keywords: PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex1; mTORC2; mTOR complex2; S6K1; p70 S6 kinase1; S6; ribosomal protein S6; 4E-BP1; eIF4E1 binding protein1; eIF2α; eukaryotic initiation factor 2α; PKR; ds RNA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling

Keywords: miRNA; microRNA; EGFR; epidermal growth factor receptor; PI3K; phosphatidyl inositide 3 kinase; DNA-PKcs; DNA-dependent protein kinase; microRNA-7; EGFR; PI3K; Akt; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799

Keywords: PI3K; Cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibitory effect of Sanguisorba officinalis ethanol extract on NO and PGE2 production is mediated by suppression of NF-κB and AP-1 activation signaling cascade

Keywords: PG; prostaglandin; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; (TNF)-α; tumor necrosis factor; ERK; extracellular signal-related kinase; TLR; toll-like receptors; MAPK; mitogen activated protein kinase; NF-κB; nuclear factor-κB;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of novel class 1 phosphatidylinositide 3-kinases (PI3K) fragment inhibitors through structure-based virtual screening

Keywords: Docking; Fragment-based; Phosphatidylinositide 3-kinase; PI3K; p110β inhibitor; Virtual screening

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway

Keywords: AD; Alzheimer's disease; ERT; estrogen replacement therapy; SERMs; selective estrogen receptor modulators; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetraz-olium bromide; LDH; Lactate dehydrogenase; FACS; Fluorescence activated cell sorting; PBS; phos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Prevention of the wortmannin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents

Keywords: wortmannin; sulfhydryl reducing agent; phosphoinositide 3-kinase; PI3K; 2-mercaptoethanol; dithiothreitol

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Activation of PI3K/mTOR signaling pathway contributes to induction of vascular endothelial growth factor by hCG in bovine developing luteal cells

Keywords: PI3K; mTOR; HIF-1α; VEGF; Letual cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways

Keywords: Psoralidin; LPS; Syk; PI3K; IKK; NF-κB; iNOS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury

Keywords: mesenchymal stem cells; ischemia reperfusion; paracrine; growth factors; PI3K; cardioprotection;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Antiapoptotic Intervention in Repeated Blood Cardioplegia: A Porcine Study of Myocardial Function

Keywords: 31; Erk1/2; extracellular signal-regulated kinase; GSK3β; glycogen-synthase kinase; IGF-I/IGF-II; insulin-like growth factor; MEK1/2; mitogen-activated protein kinase; mPTP; mitochondrial permeability transition pore; mTOR; mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Glabridin protects osteoblastic MC3T3-E1 cells against antimycin A induced cytotoxicity

Keywords: Glabridin; Mitochondrial dysfunction; Osteoblastic MC3T3-E1 cells; PI3K; CREB;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice

Keywords: G-CSF; ERK; JNK; p38; PI3K; Spinal; Pain; Hyperalgesia; Nociception; Hot plate; Morphine; Opioid;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo

Keywords: AICAR; 5-aminoimidazole-4-carboxamide 1-β-d-furanoside; AMPK; adenosine monophosphate-activated protein kinase; HUVEC; human umbilical vein endothelial cells; NF-κB; nuclear factor kappa-B; PI3K; phopsphatidyl inositol-3kinase; iNOS; inducible nitric ox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors

Keywords: Neural progenitor cells; Electric field; Cell migration; PI3K; Akt; Growth factors;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Moving in the right direction: How eukaryotic cells migrate along chemical gradients

Keywords: Chemotaxis; Dictyostelium; Neutrophils; PI3K; PTEN; TORC2; LEGI

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleHepatitis B virus X protein stimulates IL-6 expression in hepatocytes via a MyD88-dependent pathway

Keywords: HCC; hepatocellular carcinoma; HBV; hepatitis B virus; IL-6; interleukin-6; MyD88; myeloid differentiation factor 88; TGF-β; transforming growth factor β; ERK; extracellular signal-stimulated kinase; TLR; Toll-like receptor; PI3K; phosphatidylinositol-3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Rho GTPases as regulators of morphological neuroplasticity

Keywords: C3; Clostridium botulinum ribosyltransferase; cAMP; cyclic adenosine monophosphate; Cdc42; cell division control protein 42 homolog; CRIB; Cdc42/Rac interactive binding; DRG; dorsal root ganglia; ERK; extracellular signal-regulated kinase; FAK; focal adhe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

AKT Signaling Pathway in the Nucleus Accumbens Mediates Excessive Alcohol Drinking Behaviors

Keywords: Addiction; AKT; alcohol; GSK-3; nucleus accumbens; PI3K;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Sensitizing effect of 3-methyladenine on radiation-induced cytotoxicity in radio-resistant HepG2 cells in vitro and in tumor xenografts

Keywords: Liver cancer; Radio-resistance; Autophagy; 3-MA; 3-methyladenine; AO; acridine orange; AVOs; acidic vesicular organelles; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HCC; hepatocellular carcinoma; IR; ionizing radiation; mTOR; mammalian target of rap

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)–Nrf2–ARE signaling and ROS–PI3K/Akt signaling in an NF-κB-independent mechanism

Keywords: Bay 11-7082; Heme oxygenase-1; NF-κB; Reactive oxygen species; Nrf2; PI3K

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Oncogenic mutations in gastric cancer with microsatellite instability

Keywords: Gastric cancer; MAPK; Oncogenic mutations; MSI; KRAS; MLK3; PI3K; EGFR; BRAF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition

Keywords: Pim 1; Kinase inhibitors; PI3K; AML

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of sodium transport in the inner ear

Keywords: ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; EIPA; ethylisopropylamiloride; EMNE; extramacular non-sensory epithelium; ENaC; epithelial sodium channel; LAASC; low-amiloride-affinity Na+ channel; Nedd; neural precursor cell-expressed

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes

Keywords: iNOS; inducible nitric oxide synthase; NO; nitric oxide; GCDC; glycochenodeoxycholate; SNAP; S-nitroso-N-acetyl-penicillamine; SNP; sodium nitroprusside; PI3K; Phosphoinositide 3-kinase; NF-κB; nuclear factor kappaB; p38MAPK; P38 mitogen-activated protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The localisation of PtdIns3P in Drosophila fat responds to nutrients but not insulin: a role for Class III but not Class II phosphoinositide 3-kinases

Keywords: AEL; after egg lay; eL3; early third larval instar; hVps15; mammalian vacuolar protein sorting 15 homologue; hVps34; mammalian vacuolar protein sorting 34 homologue; L3; third larval instar; MTM; myotubularin; PI3K; phosphoinositide 3-kinase; S6K1; S6 kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells

Keywords: miR-29a; PEPCK; PI3K; Diabetes; Insulin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Leptin differentially regulates NPY secretion in hypothalamic cell lines through distinct intracellular signal transduction pathways

Keywords: Neuropeptide Y; Secretion; Leptin; Signal transduction; AMPK; PI3K; MAPK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of novel 2-arylamino-3-(arylsulfonyl)quinoxalines as PI3Kα inhibitors

Keywords: 2-Arylamino-3-(arylsulfonyl)quinoxaline; PI3K; PI3Kα; Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Identifying Inhibitors of Epithelial-Mesenchymal Transition by Connectivity Map–Based Systems Approach

Keywords: TGF-beta; Epithelial-mesenchymal transition; Connectivity map; Lung cancer; mTOR; PI3K; HSP90

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

16-Hydroxycleroda-3,13-dien-15,16-olide deregulates PI3K and Aurora B activities that involve in cancer cell apoptosis

Keywords: PL3, 16-hydroxycleroda-3,13-dien-15,16-olide; APK, mitogen-activated protein kinases; CPC, chromosomal passenger complex; INCENP, inner centromere protein16-Hydroxycleroda-3,13-dien-15,16-olide; Aurora B; PI3K; Mitotic block; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

IL-15 and dendritic cells induce proliferation of CD4+CD25+ regulatory T cells from peripheral blood

Keywords: Akt; protein kinase B; APC; antigen presenting cell; CPC; cytokine presenting cell; cpm; counts per minute; DC; dendritic cell; ERK; extracellular signal-regulated kinase; GM-CSF; granulocyte-macrophage clone stimulating factor; 3H-TdR; 3H-thymidine deoxy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleAltered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway

Keywords: PI3K; phosphatidylinositol 3-kinase; Tg; transgenic; FA; fatty acid; OA; oleic acid; HCC; hepatocellular carcinoma; PTEN; phosphatase and tensin homolog deleted on chromosome 10; FBS; fetal bovine serum; Erk; extracellular signal-regulated kinase; WT; wil

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of ceramide synthesis reverses endothelial dysfunction and atherosclerosis in streptozotocin-induced diabetic rats

Keywords: DC group; diabetic control group; NC group; normal control group; MTD group; myriocin treated diabetic group; SPT; serine palmitoyl-CoA transferase; EDVD; endothelium-dependent vasodilation; EC; endotheliocyte; IRS; insulin receptor substrate; PI3K; phosp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The Role of Phosphatidylinositol 3-Kinase Signaling Pathways in Pancreatic Cancer

Keywords: Pancreatic cancer; PI3K; Signaling pathway;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه