دانلود مقالات ISI درباره Pi3K + ترجمه فارسی

The Drosophila larva as a tool to study gut-associated macrophages: PI3K regulates a discrete hemocyte population at the proventriculus

Keywords: Haemocyte; Gut; Intestine; Innate immunity; Insect; Migration; Phagocytosis; PV; proventriculus; L3W; L3 wandering larvae; DH31; diuretic hormone 31; PI3K; phosphoinositide 3-kinase; DN; dominant negative; CA; constitutively active;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Staurosporine-induced apoptosis presents with unexpected cholinergic effects in a differentiated neuroblastoma cell line

Keywords: AChE; acetylcholinesterase; AChE-T; tailed AChE; AChE-R; readthrough AChE; AMP-PNP; adenosine 5′-(β,γ-imido)triphosphate; AV; Annexin V-FITC; ChAT; choline acetyltransferase; FBS; fetal bovine serum; HACU; high affinity choline uptake; HC-3; hemicholi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The role of amino acid transporters in GSH synthesis in the blood-brain barrier and central nervous system

Keywords: AA; amino acid; AARE; amino acids response elements; ApN; aminopeptidase N; ARE; antioxidant response element; BBB; blood-brain barrier; BEC; brain endothelial cell; CNS; central nervous system; CSF; cerebrospinal fluid; EC; endothelial cell; ERK; extra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats

Keywords: DAG; des-acyl ghrelin; GHS-R1a; growth hormone secretagogue receptor 1a; GHRP-2; growth hormone releasing peptide 2; GSK3β; glycogen synthase kinase-3 beta; IGF-I; insulin-like growth factor 1; IL-6; interleukin-6; MAFbx; muscle atrophy F-box protein/atr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Keywords: BCA; bicinchoninic acid protein; ECL; enhanced chemiluminescence; IR; insulin receptor; mTOR; mammalian target of rapamycin; mTORC1; mammalian target of rapamycin complex 1; mTORC2; mammalian target of rapamycin complex 2; NODAT; new onset diabetes after

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Restoration of glucose metabolism in leptin-resistant mouse hearts after acute myocardial infarction through the activation of survival kinase pathways

Keywords: AMPK; AMP activated protein kinase; ATP; adenosine triphosphate; CNTF; ciliary neurotrophic factor; FA; fatty acid; MDA; malondialdehyde; MI; myocardial infarction; ObR; leptin receptor; ObRKO; leptin receptor knockout; ObR+/+; oil treated ObRKO mice; ObR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Keywords: ARE; Antioxidant response element; DCF; 2′,7′-dichlorofluorescein; DDC; 2′,3′-dihydroxy-4′,6′-dimethoxychalcone; DHE; Dihydroethidium; DMSO; Dimethyl sulfoxide; EI; Electron impact; ETH; Ethidium; γ-GCS; ⁎γ-glutamylcysteine synthetase; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia

Keywords: LD; lipid droplet; TG; triglyceride; TLR4; Toll-like receptor 4; LPS; lipopolysaccharides; ADRP; adipocyte differentiation-related protein; CNS; central nervous system; NO; nitric oxide; MAPK; mitogen-activated protein kinases; JNK; c-Jun N-terminal kinas

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Redox control of cytosolic Akt phosphorylation in PTEN null cells

Keywords: AMS; 4-acetamido-4-maleimidylstilbene-2, 2-disulfonic acid; DDC; diethyldithiocarbamate; DMSO; dimethyl sulfoxide; DPI; diphenyleneiodonium; MEFWT; wild-type mouse embryonic fibroblasts; MEFPTEN−/−; PTEN knockout mouse embryonic fibroblasts; O2•−;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Interferon gamma induces actin polymerization, Rac1 activation and down regulates phagocytosis in human monocytic cells

Keywords: IgG receptors; Macrophages; F-actin; Cytoskeleton; Phagocytosis; PI3K; DBA; 3,3′-diaminobenzidine; FBS; fetal bovine serum; FcγR; receptor for the Fc portion of IgG; GMF; geometric mean of fluorescence intensity; HRP; horseradish peroxidase; IgG-SRBC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38

Keywords: AKT/PKB; protein kinase B; AP-1; activator protein-1; ARE; antioxidant response element; CHX; cycloheximide; DAPI; 6-diamidino-2-phenylindole; DTT; dithiothreitol; ERK; extracellular regulated kinase; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosp

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus

Keywords: AFM; atomic force microscopy; CC50; 50% cytotoxic concentration; CPE; cytopathic effect; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DPBS; Dulbecco's phosphate-buffered saline; EC50; half maximal effective concentration; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Lithium attenuates bupivacaine-induced neurotoxicity in vitro through phosphatidylinositol-3-kinase/threonine-serine protein kinase B- and extracellular signal-regulated kinase-dependent mechanisms

Keywords: lithium; local anesthetics; neurotoxicity; PI3K; Akt signaling; ERK signalingAkt, threonine-serine protein kinase B; API, triciribine; Bup, bupivacaine; ERK, extracellular signal-regulated kinase; GSK-3β, glycogen synthase kinase-3β; JC-1, 5,5′,6,6′-tetra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks

Keywords: Abl; Abelson tyrosine-protein kinase 1; ADAP1; arf-GAP with dual PH domain-containing protein 1; AFM; atomic force microscopy; cAMP; cyclic adenosine monophosphate; ApoER2; apolipoprotein E receptor 2; BCAR1; breast cancer anti-estrogen resistance 1; p130

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor-associated kinase M

Keywords: IL-13; IL-1 receptor-associated kinase M; Toll-like receptor 2; airway epithelial cells; ALI; Air-liquid interface; AP-1; Activator protein 1; BEGM; Bronchial epithelial cell growth medium; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; hBD2; Human β

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy

Keywords: Cancer therapy; Regrowth resistance; PI3K; mTOR; NVP-BEZ235

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

EGF-like peptide-enhanced cell movement in Dictyostelium is mediated by protein kinases and the activity of several cytoskeletal proteins

Keywords: EGF; epidermal growth factor; EGFL; EGF-like; EGFL1; 1st EGFL repeat of CyrA; EGFR; EGF receptor; EGFRL; EGFR-like protein; Ten14; 14th EGFL repeat of tenascin C; ECM; extracellular matrix; CaM; calmodulin; CaMBP; CaM binding protein; MHC; myosin II heavy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Role of the phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways in the neuroprotective effects of cilnidipine against hypoxia in a primary culture of cortical neurons

Keywords: CCBs; calcium channel blockers; COX; cyclooxygenase; DAPI; DNA-specific fluorochrome 4′,6-diamidino-2-phenylindole dihydrochloride; DCF; 2′7′-dichlorofluorescein; DCFH-DA; dichlorodihydrofluorescein diacetate; DCFH2; 2′,7′-dichlorodihydrofluores

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA

Keywords: OX40L; Fyn; PI3K; mast cell; degranulation; anaphylaxis; BM; Bone marrow; Cbp; C-terminal Src kinase-binding protein; Csk; C-terminal Src kinase; DNP; Di-nitro-phenyl; MC; Mast cell; MTOC; Microtubule organizing center; NIH; National Institutes of Healt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF)

Keywords: MEF; mouse embryonic fibroblast; TX; tamoxifen; VH; vehicle; SEM; standard error of the mean; SRC; scramble RNA control; LY; LY294002.; ILK; Wound healing; HGF; Proliferation; Conditional ILK-KO mice; PI3K;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness

Keywords: Asthma; airway hyperresponsiveness; airway smooth muscle mass; airway smooth muscle contraction; Ca2+ mobilization; extracellular signal-regulated kinase; G protein-coupled receptors; knockout mice; ovalbumin-sensitized/-challenged murine model of asth

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor

Keywords: ACE-2; angiotensin converting enzyme-2; ANG (1-7); angiotensin-(1-7); ANG-II; angiotensin-II; ARBs; angiotensin receptor blockers; AT1R; angiotensin-II type 1 receptor; AT2R; angiotensin-II type 2 receptor; DHE; dihydroethidium; EAM; experimental autoim

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Potential roles of PI3K/Akt and Nrf2-Keap1 pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygen and glucose deprivation

Keywords: Z-ligustilide; Oxygen glucose deprivation; PI3K; Nrf2 pathway; Heme oxygenase-1; Hormetic effect;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Sp1 is involved in regulation of cystathionine γ-lyase gene expression and biological function by PI3K/Akt pathway in human hepatocellular carcinoma cell lines

Keywords: CSE; cystathionine γ-lyase; PLP; pyridoxal-5′-phosphate; PI3K; phosphoinositide 3-kinase; Myr-Akt2; myristylated variants of Akt2; IGF-1; insulin-like growth factor-1; PTEN; phosphatase and tensing homolog; CHX; cycloheximide; MEF; mouse embryonic fibr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

ATP acts as a survival signal and prevents the mineralization of aortic valve

Keywords: Calcific aortic valve disease; Aortic stenosis; P2Y2 receptor; PI3K; Ectonucleotidase; ENPP1; ATP; Mineralization

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The role of pseudokinases in cancer

Keywords: ALL; Acute Lymphoblastic Leukaemia; AML; Acute Myeloid Leukaemia; AMPK; 5′-Adenosine Monophosphate Activated Protein Kinase; ATF4; Activating Transcriptional Factor 4; ATP; Adenosine-5′-Triphosphate; BTICs; Brain Tumour-Initiating Cells; C/EBPα; CCAA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Perspectives des thérapies ciblées dans le cancer du sein métastatique

Keywords: thérapie ciblée; cancer du sein métastatique; HER-2; anti-angiogénèse; étude clinique; targeted therapy; metatstatic breast cancer; HER-2; anti-agiogenesis; clinical trial; ADCC; cytotoxicité à médiation cellulaire anticorps-dépendante; Akt; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

The Transcriptional Consequences of Somatic Amplifications, Deletions, and Rearrangements in a Human Lung Squamous Cell Carcinoma

Keywords: lincRNA; long intergenic non-coding RNA; miRNA; microRNA; ncRNA; non-coding RNA; PI3K; phosphatidylinositol 3-kinase; SCC; squamous cell carcinoma; snoRNA; small nucleolar RNA, RNA; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin

Keywords: IL-33; TH2; innate lymphoid cells; asthma; mammalian target of rapamycin; rapamycin; AHR; Airway hyperresponsiveness; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; Lin; Lineage-specific marker;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Research ReportHyperstimulation of macropinocytosis leads to lysosomal dysfunction during exposure to methamphetamine in SH-SY5Y cells

Keywords: FITC; fluorescein isothiocyanate; FTS; farnesyl thiosalicylic acid; GFP; green fluorescent protein; LC3; microtubule‐associated protein 1 light chain 3; METH; methamphetamine; MAPK; mitogen‐activated protein kinase; PI; propidium iodide; PI3K; phospho

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Potent vasodilation effect of amurensin G is mediated through the phosphorylation of endothelial nitric oxide synthase

Keywords: ACC; acetyl-CoA carboxylase; ACh; acetylcholine; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; adenosine 5′-monophosphate-activated protein kinase; CA-AMPK; constitutive active AMPK; CaMK II; calmodulin-dependent protein kinase II;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

What We Have Learned About Pancreatic Cancer From Mouse Models

Keywords: COX; cyclooxygenase; CT; computed tomography; FDG-PET; 18F-fluoro-2-deoxyglucose positron emission tomography; GEMM; genetically engineered mouse model; IPMN; intraductal papillary mucinous neoplasm; MAPK; mitogen-activated protein kinase; MCN; mucinous c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Exchange protein activated by cyclic adenosine monophosphate regulates the switch between adipogenesis and osteogenesis of human mesenchymal stem cells through increasing the activation of phosphatidylinositol 3-kinase

Keywords: hMSCs; Epac; PI3K; Adipogenesis; Osteogenesis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Campylobacter jejuni Induces Colitis Through Activation of Mammalian Target of Rapamycin Signaling

Keywords: Crypt Abscesses; Imaging; Mouse Model; Immune Response; Signal Transduction; CFU; colony-forming unit; EGFP; enhanced green fluorescent protein; FISH; fluorescence in situ hybridization; IL; interleukin; MLN; mesenteric lymph node; mTOR; mammalian target

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

Keywords: Chemoprevention; Colon Cancer; Oncogene; Tumor Suppressor; ACC; acetyl-CoA carboxylase; ADP; adenosine diphosphate; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; CRC; colorectal cancer; eIF4E; eukaryotic translatio

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Oncogenic Pathways, Molecularly Targeted Therapies, and Highlighted Clinical Trials in Non–Small-Cell Lung Cancer (NSCLC)

Keywords: MET; EGFR; EML4-ALK; IGF-1R; KRAS; LKB1; Lung cancer; PI3K; Targeted therapies

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Protective potential of IL-6 against trimethyltin-induced neurotoxicity in vivo

Keywords: γ-GCL; γ-glutamylcysteine ligase; GSH; reduced glutathione; GSSG; oxidized glutathione; HO-1; heme oxygenase-1; TNF-α; tumor necrosis factor-α; IFN-γ; interferon-γ; IL-6; interleukin-6; rIL-6; recombinant IL-6 protein; Nrf2; NF-E2-related factor 2;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagy and polyglutamine diseases

Keywords: HD; Huntington's disease; SCA; spinocerebellar ataxia; DRPLA; Denatorubral-pallidoluysian atrophy; SBMA; spinal and bulbar muscular atropy; Htt; Huntingtin; UPS; ubiquitin-proteasome system; HDL-2; Huntington's disease-like 2; IBs; inclusion bodies; RNA

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis

Keywords: 7α-OH; 7α-hydroxycholesterol; 7-K; 7-ketocholesterol; 9-ONC; 9-oxononanoyl cholesterol; 15d-PGJ2; 15-deoxy-Δ12,14-prostaglandin J2; α-EPOX; 5α,6α-epoxycholesterol; AP-1; activator protein-1; ARE; antioxidant-responsive element; ATF; activating trans

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Phenotypic characterization of lung macrophages in asthmatic patients: Overexpression of CCL17

Keywords: Asthma; macrophage; chemokine; steroid; AF647; Alexa Fluor 647; APC; Allophycocyanin; APC-Cy7; Allophycocyanin-cyanine 7; Arg1; Arginase 1; BAL; Bronchoalveolar lavage; CLEC10A; Macrophage galactose C-type lectin (CD301); COPD; Chronic obstructive pulmo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Redox-regulating role of insulin: The essence of insulin effect

Keywords: 4-HNE; 4-hydroxynonenal; 8-OHdG; 8-hydroxydeoxyguanosine; 8-OHG; 8-hydroxyguanine; 8-iso-PGF2α; 8-iso-prostaglandin F2α; AD; Alzheimer's disease; AIDS; acquired immunodeficiency syndrome; Akt; protein kinase B; AMI; acute myocardial infarction; APS; a

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Using mice to unveil the genetics of cancer resistance

Keywords: AC; adenocarcinoma; AOM; azoxymethane; APC; antigen-presenting cells; BH; BCL2 homology; CCl4; carbon tetrachloride; cM; centimorgan; COX; cyclo-oxygenase; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DEN; diethylnitrosamine; DMBA; 7,12-

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner

Keywords: PDK1; 3-phosphoinositide-dependent protein kinase 1; PI3K; phosphatidylinositol 3 kinase; PIP3; phosphatidylinositol 3,4,5 triphosphate; PH; pleckstrin homology; shRNA; short hairpin RNA;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics

Keywords: Akt; protein kinase B; EGFR; epidermal growth factor receptor; ERK; extracellular-regulated kinase; FasL; Fas ligand; JNK; c-Jun N-terminal kinase; MAPK; mitogen activated protein kinase; NF-κB; nuclear factor kappa B; PCD; programmed cell death; PI3K; p

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

PTEN inhibitors cause a negative inotropic and chronotropic effect in mice

Keywords: PTEN; PI3K; Cardiac contractility; Reperfusion injury; Myocardial infarction

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors

Keywords: PI3K; mTOR; Kinase inhibitor; iMHBS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Neuregulin-1β regulates outgrowth of neurites and migration of neurofilament 200 neurons from dorsal root ganglial explants in vitro

Keywords: CNTF; cholinergic neurotrophic factor; DRG; dorsal root ganglion; DRGs; dorsal root ganglia; DMEM/F-12; Dulbecco's Modified Eagle Medium with F-12 supplement; E15; embryonic day 15; Egr-3; early growth response 3; NF; neurofilament; NF-200; neurofilament

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk

Keywords: AKT; acutely transforming retrovirus AKT8 in rodent T cell lymphoma; BCR; B cell receptor; Btk; Bruton's tyrosine kinase; ChIP; chromatin immunoprecipitation; GCN5; general control non-depressible 5; H2O2; hydrogen peroxide; HAT; histone acetyltransfera

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability

Keywords: mTOR; PI3K; Torin1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه