Glabridin protects osteoblastic MC3T3-E1 cells against antimycin A induced cytotoxicity

► Glabridin restored mitochondrial dysfunction that was induced by antimycin A treatment. ► Glabridin scavenged ROS and mitochondrial superoxide anions generated by antimycin A. ► Glabridin prevented antimycin A-induced nitrotyrosine increase and thioredoxin reductase inactivation. ► Glabridin restored antimycin A-induced inactivation of PI3K and CREB.