دانلود مقالات ISI درباره LIKK + ترجمه فارسی

پیوستن به انتهای غیرخطی: راه حل خوبی برای پایان دادن به بد است

Nonhomologous end joining: A good solution for bad ends

Keywords: LIKK; Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats

Keywords: LIKK; LBP; Lycium barbarum polysaccharide; DM; diabetes mellitus; DPN; diabetic peripheral neuropathy; LC3-II; microtubule-associated protein 1 light chain 3-II; HDL; high density lipoprotein; SC; Schwarm cell; STZ; streptozotocin; LA; lipoic acid; PWT; paw wit

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum

Keywords: LIKK; GSH; Cysteine transport; NGF; mTOR; Redox; Cerebellum; 4F2hc; 4F2 cell surface antigen; BBB; blood-brain barrier; BSO; L-buthionine-S-R-sulfoximine; CNS; central nervous system; DAPI; 4′,6-diamidino-2-phenylindole DTPA; diethylenetriamine penta-acetic a

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Sustained anti-inflammatory effects of TGF-β1 on microglia/macrophages

Keywords: LIKK; bFGF; basic fibroblast growth factor; Contra; contralateral cortex; DAMPs; damage-associated molecular patterns; dpr; days post-reperfusion; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HGF; hepatocyte growth factor; HMGB1; high mobility group box 1;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Original ArticleThe depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades

Keywords: LIKK; ATM; Colon cancer; B56γ2; CD44; Tumorigenic potential; ATM; Ataxia-telangiectasia mutated; PIKK; phosphatidylinositol-3 kinase related kinase; FAT; FRAP-ATM-TRRAP domain; FATC; FAT-C-terminal domain; DDR; DNA damage response; DSBs; double strand breaks;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of kinases phosphorylating 13 sites in the nuclear, DNA-binding protein NUCKS

Keywords: LIKK; NUCKS; nuclear, ubiquitous, casein kinase and cyclin kinase substrate; NLS; nuclear localization signal; CK2; casein kinase 2; DNA-PK; DNA activated kinase; PIKK; phosphatidylinositol 3-kinase-related kinase; ATM kinase; ataxia telangiectasia mutated kina

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors

Keywords: LIKK; ATR; ataxia telangiectasia and Rad-3 related protein; PIKK; phosphatidylinositol 3-kinase-related protein kinase; ATM; ataxia telangiectasia mutated; mTOR; mammalian target of Rapamycin; DNA-PK; DNA-dependent protein kinase; 3D; three-dimensional; MCL; ma

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

ATR-mediated regulation of nuclear and cellular plasticity

Keywords: LIKK; ATR; Ataxia Telangiectasia and Rad3-related; PIKK; Phosphatidylinositol 3-Kinase-related Kinases; PTM; Post Translation Modification; ssDNA; single stranded DNA; ATRIP; ATR interacting protein; RPA; Replication Protein A; DDR; DNA damage response; HEAT; H

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Melanoma antigen-D2: A nucleolar protein undergoing delocalization during cell cycle and after cellular stress

Keywords: LIKK; CPT; Camptothecin; CTA; Cancer/testis antigen; DFC; Dense fibrillar component; DRB; 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole; eGFP; Enhanced green fluorescent protein; FBL; Fibrillarin; FC; Fibrillar center; GC; Granular component; MAGE; Melanoma

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases

Keywords: LIKK; FKH-TF; forkhead transcription factor; FoxO; forkhead box O family; HA; hemagglutinin; PIKK; phosphatidylinositol kinase-related kinase; PI3K; phosphoinositide 3-kinase; ROS; reactive oxygen species; RT-PCR; quantitative real-time PCR; Forkhead transcript

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis

Keywords: LIKK; NF-κB; Sinomenine; Invasion and metastasis; IKK phosphorylation; CUEDC2; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; EMT; epithelial-mesenchymal transition; IκB; inhibitor of NF-κB; IKK; IκB kinase; pIKK; phosphorylated I

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

Keywords: LIKK; DNA-dependent protein kinase; Non-homologous end joining; Mitosis; ATM; ataxia telangiectasia mutated; ATR; ATM- and Rad3-related; ds; double-stranded; cryo-EM; cryo-electron microscopy; DSB; DNA double strand break; DNA-PK; DNA-activated/dependent protei

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2015 سفارش ترجمه

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity

Keywords: LIKK; AHR; aryl hydrocarbon receptor; ALDH; aldehyde dehydrogenase; CDK; cyclin-dependent kinase; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; CSE; cigarette smoke extract; DDR; DNA damage response; FA; Fanconi anemia; FANCD2; a member of t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair

Keywords: LIKK; APE1; apurinic/apyrimidinic endonuclease; A-T; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; DNA double-strand break; ECL; enhanced chemiluminescence; F

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The structural basis for mTOR function

Keywords: LIKK; mTOR; PI3K; Rapamycin; 4E-BP1; S6K1; PIKK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy

Keywords: LIKK; CMC; critical micelle concentration; DihepPC; 1,2-diheptanoyl-sn-glycero-3-phosphocholine; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DPC; dodecylphosphocholine; FAT(C); FRAP, ATM, TRRAP (C-terminal); GB1; B1 immunoglobulin binding domain of strep

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A

Keywords: LIKK; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; ATRIP; ATR-interacting protein; CDK; cyclin-dependent kinase; CIP; calf intestinal phosphatase; DDR; DNA damage response; DNA-PKcs; D

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR signaling in tumorigenesis

Keywords: LIKK; mTOR; the mechanistic target of rapamycin or the mammalian target of rapamycin; PIKK; phosphoinositide 3-kinase related protein kinase; ATM; ataxia-telangiectasia mutated; ATR; ataxia-telangiectasia and rad3-related; DNAPK; DNA-dependent protein kinase; R

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

Keywords: LIKK; MDA; malondialdehyde; 4-HNE; 4-hydroxynonenal; EAE; experimental allergic encephalomyelitis; MS; mutiple sclerosis; SSB; single strand break; DSB; double strand break; 8-OxoG; 8-hydroxyguanosine; 8-NO(2)-G; 8-nitroguanine; AP; apurinic/apyrmidinic; OGG1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The role of pseudokinases in cancer

Keywords: LIKK; ALL; Acute Lymphoblastic Leukaemia; AML; Acute Myeloid Leukaemia; AMPK; 5′-Adenosine Monophosphate Activated Protein Kinase; ATF4; Activating Transcriptional Factor 4; ATP; Adenosine-5′-Triphosphate; BTICs; Brain Tumour-Initiating Cells; C/EBPα; CCAA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: LIKK; 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

Cell context-dependent involvement of ATR in early stages of retroviral replication

Keywords: LIKK; PIKK; ATR; ATM; DNA repair; Integration; Retroviral replication; Caffeine; Wortmannin; Antiviral chemotherapy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Insights into the domain and repeat architecture of target of rapamycin

Keywords: LIKK; Protein repeats; HEAT; TPR; TOR; HHpred; PIKK;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Common mechanisms of PIKK regulation

Keywords: LIKK; ATR; ATM; DNA-PK; mTOR; SMG1; PIKK

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Induction of genomic instability in cultured human colon epithelial cells following exposure to isocyanates

Keywords: LIKK; Genomic instability; DNA damage; Apoptosis; Inflammation; Isocyanates; MIC; Methyl isocyanate; ATM; Ataxia telangiectasia mutated; PIKK; Phosphoinositide-3-kinase-like kinases; DAPI; 4′, 6′-Diamidino-2-phenylindole dihydrochloride; FITC; Fluorescence

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin

Keywords: LIKK; DNA damage; MRN complex; PIKK; Mre11 phosphorylation; Checkpoint recovery;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase η-deficient human cells treated with cisplatin and oxaliplatin

Keywords: LIKK; ICL; interstrand crosslink; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR interacting protein; PIKK; PI-3 kinase-related protein kinase; DNA-PK; DNA-dependent protein kinase; Polη; DNA polymerase η; RPA; replication protein A

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

The DNA damage response during an unperturbed S-phase

Keywords: LIKK; A-T; Ataxia-Telangiectasia; ATM; Ataxia-Telangiectasia Mutated; ATR; ATM and Rad3 related (mec1); DSBs; double-strand breaks; ssDNA; single strand DNA; PIKK; phosphoinositol kinase like kinase; IR; ionizing radiation; UV; ultraviolet; HU; hydroxyure

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: Involvement of ATM pathway

Keywords: LIKK; ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related protein; DMSO; dimethyl sulfoxide; DNA-PK; DNA-activated protein kinase; DSB; DNA double-strand break; ERK; extracellular signal-regulated protein kinase; HRP; horseradish peroxidase; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage

Keywords: LIKK; DNA damage response; NBS1; PIKK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of the cloned full-length and a truncated human target of rapamycin: Activity, specificity, and enzyme inhibition as studied by a high capacity assay

Keywords: LIKK; TOR; Rapamycin; PIKK; Kinase inhibitor; Anticancer; High-throughput screening;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

The role of SMG-1 in nonsense-mediated mRNA decay

Keywords: LIKK; NMD; nonsense-mediated mRNA decay; EJC; exon-junction complex; PTC; premature translation termination codon; IC; initial SMG-1-Upf1 complex; PIKK; phosphoinositide 3-kinase related kinase; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3 related;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه