Preparation and characterization of curcumin-piperine dual drug loaded nanoparticles
Keywords: Polymeric nanoparticles; Cancer treatment; Nanoparticles; Curcumin; Piperine;
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Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis
Keywords: EGCG; Epigallocatechin-3-gallate; DSS; dextran sodium sulfate; ROS; reactive oxygen species; SOD; superoxide dismutase; CAT; catalase; GPO; gluthathione peroxidase; ERK; extracellular signal-regulated kinase; MPO; myeloperoxidase; MDA; malondialdehyde; TB
Involvement of serotonergic system in the antidepressant-like effect of piperine
Keywords: 5-HT, serotonin; 5-HTP, 5-hydroxy-l-tryptophan; i.p., intraperitoneally; pCPA, p-chlorophenylalanineAntidepressant; Mice; Piperine; Serotonergic system
Role of 5-HT1A and 5-HT1B receptors in the antidepressant-like effect of piperine in the forced swim test
Keywords: Piperine; Antidepressant; Forced swim test; Serotonin receptor
TRPV1 agonist piperine but not olvanil enhances glutamatergic spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons
Keywords: Spinal dorsal horn; Excitatory transmission; Olvanil; Piperine; TRPV1 channel;
Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage
Keywords: Curcumin; Piperine; Benzo(a)pyrene; Genoprotective;
Simultaneous UFLC–ESI–MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: Application to pharmacokinetic studies in rats
Keywords: Piper longum L.; Piperine; Piperlonguminine; UFLC–ESI–MS/MS; Pharmacokinetics
Piperidine alkaloids from Piperretrofractum Vahl. protect against high-fat diet-induced obesity by regulating lipid metabolism and activating AMP-activated protein kinase
Keywords: AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; SREBPs; sterol regulatory element-binding proteins; FAS; fatty acid synthase; CPT; carnitine palmitoyltransferase; UCP; uncoupling protein; PPAR; peroxisome proliferator-activated receptor;
Piperine ameliorates the severity of cerulein-induced acute pancreatitis by inhibiting the activation of mitogen activated protein kinases
Keywords: Piperine; Acute pancreatitis; Cerulein; Acinar cells; Cytokine; Mitogen activated protein kinases
Leishmanicidal effects of piperine, its derivatives, and analogues on Leishmania amazonensis
Keywords: Piper nigrum; Piperaceae; Leishmania amazonensis; Piperine; Phenylamide; Leishmaniasis treatment;
Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression
Keywords: Piperine; MMP-9; PKCα; Invasion; Antitumor activity
Proposed structural basis of interaction of piperine and related compounds with monoamine oxidases
Keywords: Piperine; Monoamine oxidase; Docking; AutoDock
Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease
Keywords: Piperine; Spatial memory; Neuroprotective; Neurotrophic effect; mg/kg; milligram/kilogram; BW; body weight; gm; gram; Inc.; incorporated; cm; centimeter; C; Celsius; NE; northeast; NW; northwest; SE; southeast; SW; southwest; N; North; E; East; S; South;
Correlation of metabolites in the leaf and berries of selected black pepper varieties
Keywords: Black pepper; Essential oil; Piperine; Caryophyllene; Germacrene-D; Elemol
Synthesis and Antileishmanial activity of Piperoyl-Amino Acid Conjugates
Keywords: Leishmaniasis; Amastigote; Amino acid; Piperine; Promastigote
In vitro TRPV1 activity of piperine derived amides
Keywords: Piperine; Piperine-derived amides; Transient receptor potential vanilloid 1; Fluorometric assays; Pain; Analgesic activity
Inhibition of lipopolysaccharide-induced inflammatory responses by piperine
Keywords: Type 1 interferon; Endotoxin shock; Interferon regulatory factor; Piperine; Signal transducer and activator of transcription
Biomolecule–metal interactions: Applications in extraction and separation techniques
Keywords: Heavy metals; Arachin; Piperine; Adsorption; Extraction; Biosorption
Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes
Keywords: Curcumin; Piperine; Chronic unpredictable stress; Forced swim test (FST); Monoamine oxidase (MAO); Serotonin
Ionic liquid-based ultrasonic-assisted extraction of piperine from white pepper
Keywords: Ionic liquids; Ultrasonic-assisted extraction; White pepper; Piperine; Ultra-performance liquid chromatography
The degradation kinetics of flavor in black pepper (Piper nigrum L.)
Keywords: Flavor degradation; Kinetics; Black pepper; Piperine; Oleoresin; Cookers
Effects of penetration enhancers on Shuangwu traumatic formula: In vitro percutaneous absorption and in vivo pharmacodynamic evaluation of an herb medicine
Keywords: The Shangwu traumatic formula; Penetration enhancer; Piperine; Hot-plate assay; Xylene-induced ears edema test
Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer
Keywords: Curcumin; Bioavailability; Nanoparticles; Oral; Piperine
Chemopreventive potential of piperine in 7,12-dimethylbenz[a]anthracene-induced skin carcinogenesis in Swiss albino mice
Keywords: Skin cancer; Piperine; Lipid peroxidation; Antioxidants; Detoxification agents
Immunomodulatory role of piperine in cadmium induced thymic atrophy and splenomegaly in mice
Keywords: Cadmium; Apoptosis; Piperine; Thymic atrophy; Splenomegaly
Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides
Keywords: Hepatoprotective activity; Piperine; Piper chaba; Piperaceae; Piperchabamide; Anti-TNF-α activity
Plasmodium chabaudi: Efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice
Keywords: Malaria; Curcumin; Piperine; Artemisinin; Artemisinin combination therapy (ACT)
Protective effects of amide constituents from the fruit of Piper chaba on d-galactosamine/TNF-α-induced cell death in mouse hepatocytes
Keywords: Piper chaba; Piperine; Piperchabamide E; Amide constituent; Hepatoprotection; TNF-α
Novel 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine as trypanocidal agents: Chemical and biological studies
Keywords: Chagas’ disease; Mesoionic compounds; 1,3,4-Thiadiazolium-2-phenylamine; Piperine; Trypanosoma cruzi
Comparative study of Rhodiola preparations on behavioral despair of rats
Keywords: Rhodiola rosea; Rhodioloside; Rosavin; Piperine; Anti-depressant; Drug–herb interaction
From lignins to tannins: Forty years of enzyme studies on the biosynthesis of phenolic compounds
Keywords: Biosynthesis; Enzymology; Carboxyl-activated 'energy-rich' intermediates; Cinnamoyl-coenzyme A thioesters; Lignin; Piperine; Tannin;
Effect of heat processing of spices on the concentrations of their bioactive principles: Turmeric (Curcuma longa), red pepper (Capsicum annuum) and black pepper (Piper nigrum)
Keywords: Capsaicin; Curcumin; Piperine; Loss during heat processing; Spice principles; Turmeric; Curcuma longa; Red pepper; Capsicum annuum; Black pepper; Piper nigrum
Studies on the in vitro absorption of spice principles – Curcumin, capsaicin and piperine in rat intestines
Keywords: Curcumin; Capsaicin; Piperine; In vitro absorption; Everted intestine; Encapsulation
Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells
Keywords: Cisplatin; Heme oxygenase; MAPK; Nrf2; Piperine
Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms
Keywords: Piperine; Hippocampal progenitor cell proliferation; Brain-derived neurotrophic factor; Antidepressant; Chronic mild stress; Primary cultured hippocampal neuron
Involvement of TRPV1-dependent and -independent components in the regulation of vagally induced contractions in the mouse esophagus
Keywords: TRPV1; Primary afferent neuron; Capsaicin; Piperine; Esophagus; Striated muscle; Vagus nerve; Esophageal motility; (Mouse); (Rat)
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats
Keywords: Ally isothiocyanate; Capsaicin; Piperine; Gastric lesion
Piperine inhibits TNF-α induced adhesion of neutrophils to endothelial monolayer through suppression of NF-κB and IκB kinase activation
Keywords: Human endothelial cells; Cell adhesion molecules; Nuclear factor-κB; Piper longum; Piperine; IκB kinase
Cytoprotective and immunomodulating properties of piperine on murine splenocytes: An in vitro study
Keywords: Piperine; Apoptosis; Oxidative stress; Phenotyping; Blastogenesis; Cadmium
In vivo effect of piperine on serum and tissue glycoprotein levels in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice
Keywords: Benzo(a)pyrene; Piperine; Lung cancer; GlycoproteinsB(a)p, benzo(a)pyrene
Piperine inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells
Keywords: 1-Methyl-4-phenylpyridinium; Piperine; PC12 cells; Mitochondrial membrane permeability; Cell injury
Modulation of cadmium induced alterations in murine thymocytes by piperine: Oxidative stress, apoptosis, phenotyping and blastogenesis
Keywords: Piperine; Murine thymocytes; Apoptosis; Oxidative stress; Phenotyping; Blastogenesis
Preliminary study on inhibition of genotoxicity by piperine in mice
Keywords: Piperine; Inhibition; Genotoxicity; Micronucleus test;
Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties
Keywords: Curcumin; Piperine; Bioconjugate; Antibacterial; Antifungal;