دانلود مقالات ISI درباره Pkb + ترجمه فارسی

Involvement of the ERK/MAP kinase signalling pathway in milli-calpain activation and myogenic cell migration

Keywords: BCA; bicinchoninic acid; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DTT; DL-dithiothreitol; EGF; epidermal growth factor; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid; ERK; extracellular-signal regulat

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Apoptosis and the cardiac action of insulin-like growth factor I

Keywords: Insulin-like growth factor; Apoptosis; Myocardium; Ischaemia; Reperfusion injury; Signaling; ARC; apoptotic repressor with CARD; ATP; adenosine triphosphate; bFGF; basic fibroblast growth factor (also known as FGF2); BAK; Bcl-2 antagonist/killer protein;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Keywords: Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Ras: The stress and the strain

Keywords: ERK; extracellular signal-regulated kinase; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; GqPCR; Gq protein-coupled receptor; GSH; glutathione; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PI3K; phosphoi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Keywords: Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Emerging role of protein kinase B/Akt signaling in pancreatic β-cell mass and function

Keywords: cdk4, cyclin-dependent kinase 4; IGFI, Insulin-like growth factor; IKB, Protein kinase B; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; PIP3, phosphatidylinositol (3,4,5)P3 phosphate; PH, pleckstrin homologyAkt; PKB; Islets; β-Cell mas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Emerging role of protein kinase B/Akt signaling in pancreatic β-cell mass and function

Keywords: cdk4, cyclin-dependent kinase 4; IGFI, Insulin-like growth factor; IKB, Protein kinase B; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; PIP3, phosphatidylinositol (3,4,5)P3 phosphate; PH, pleckstrin homologyAkt; PKB; Islets; β-Cell mas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

Keywords: Akt inhibitors; Akt; PKB; Protein kinase B; GSK3; FL5.12-Akt1; Anticancer; Apoptosis; X-ray

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

p38-MAPK and PKB/Akt, possible role players in red palm oil-induced protection of the isolated perfused rat heart?

Keywords: Red palm oil; MAPKs; PKB; Ischemia; Reperfusion

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Protein kinase Cα regulates insulin receptor signaling in skeletal muscle

Keywords: PKCα; IRS-1; PKB; Threonine phosphorylation; Serine phosphorylation; Insulin signaling; Blood glucose

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

A phototaxis signalling complex in Dictyostelium discoideum

Keywords: Dictyostelium; phototaxis; RasD; filamin; ErkB; GRP125; PKB

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Tryptase activates PKB in inflammatory reaction in ECV304 cells

Keywords: Tryptase; PAR-2; PKB; NF-κB; Inflammation; Mast cell

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Glutamate-dependent translational regulation in cultured Bergmann glia cells: Involvement of p70S6K

Keywords: p70S6K; glutamate receptors; Bergmann glia; mTOR; translational control; Akt I; 1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate; AMPA; amino α-3-hydroxy-5-methyl-4-isoaxazolepropionate; ANOVA; analysis of variance; BAPTA-AM; 1,2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Endothelial Akt activation by hyperoxia: Role in cell survival

Keywords: Hyperoxia; Akt; PKB; Endothelial; Glucose consumption; Necrosis; Mitochondria; Endoplasmic reticulum; Free radicals

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The very C-terminus of protein kinase Cɛ is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1

Keywords: aPKC; atypical PKC; cPKC; classic PKC; MD; molecular dynamics; nPKC; novel PKC; PAGE; polyacrylamide gel electrophoresis; PDK-1; 3-phosphoinositide-dependent kinase-1; PKA; cAMP-dependent protein kinase; PKB; protein kinase B; PKC; protein kinase C; RMSD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Gonadotropin-releasing hormone in apoptosis of prostate cancer cells

Keywords: Gonadotropin; Prostate cancer cells; GnRH-a; Signaling cascades; MAPK; PKB

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Differential and Epigenetic Gene Expression Profiling Identifies Frequent Disruption of the RELN Pathway in Pancreatic Cancers

Keywords: ApoER2; apolipoprotein E receptor 2; COBRA; combined bisulfite restriction analysis; 5Aza-dC; 5-aza-2′-deoxycytidine; HDAC; histone deacetylase; IPMN; intraductal papillary mucinous neoplasm of the pancreas; MSP; methylation-specific polymerase chain re

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2006 سفارش ترجمه

Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B

Keywords: PKB; Inhibitors; Cancer; Structure-based drug design

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2006 سفارش ترجمه

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

Keywords: Akt; PKB; Kinase cancer;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

SHARP-2/Stra13/DEC1 as a potential repressor of phosphoenolpyruvate carboxykinase gene expression

Keywords: 36B4; ribosomal protein 36B4; SHARP-2; enhancer of split- and hairy-related protein-2; Stra13; stimulation of retinoic acid 13; PI 3-K; phosphoinositide 3-kinase; PEPCK; phosphoenolpyruvate carboxykinase; Dex; dexamethasone; EGCG; (−)-epigallocatechin g

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Expression and purification of active PKB kinase from Escherichia coli

Keywords: PKB; Co-expression; His-tag; FLAG-tag; E. coli; Kinase; Recombinant protein;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Activation of a GST-tagged AKT2/PKBβ

Keywords: AKT; PKB; PDK1; Autophosphorylation; Baculovirus; Protein purification;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives

Keywords: Muscarinic agonist; Subtype selectivity; Dioxolane derivative; Oxathiolane derivative; Binding studies; Functional studies; CHO; Chinese hamster ovary; hm1-hm5; human muscarinic subtypes; M1-M5; muscarinic subtypes; Ki; inhibitor equilibrium dissociat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Targeted Inhibition of β-Adrenergic Receptor Kinase-1-Associated Phosphoinositide-3 Kinase Activity Preserves β-Adrenergic Receptor Signaling and Prolongs Survival in Heart Failure Induced by Calsequestrin Overexpression

Keywords: βAR; β-adrenergic receptor; βARK1; βAR kinase-1; cAMP; cyclic adenosine monophosphate; CSQ; calsequestrin; GSK; glycogen synthase kinase 3β; ISO; isoproterenol; MAPKs; mitogen-activated protein kinases; PKB; protein kinase B; PI3K; phosphoinositide-3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of the extracellular signal-regulated kinase pathway in adult myocardium: differential roles of Gq/11, Gi and G12/13 proteins in signalling by α1-adrenergic, endothelin-1 and thrombin-sensitive protease-activated receptors

Keywords: ARVM; adult rat ventricular myocytes; CPA; cyclopentyladenosine; ERK; extracellular signal-regulated kinase; ET-1; endothelin-1; EGFP; enhanced green fluorescent protein; GPCR; G protein-coupled receptor; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: From diabetes, obesity to cell cycle, and cancer

Keywords: EGFR; epidermal growth factor receptor; GHR; growth hormone receptor; IGF-IR; insulin-like growth factor I receptor; IR; insulin receptor; IRS; insulin receptor substrate; JAK; janus kinase; KO; knockout; LeptinR; leptin receptor; PDGFR; platelet derived

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Substrate specificity of protein kinases and computational prediction of substrates

Keywords: AGC; protein kinases A, G, C; AMPK; AMP-activated protein kinase; CaMK; calmodulin-dependent kinase; CDK; cyclin-dependent kinase; CMGC kinases; cyclin-dependent kinases, MAP kinases, glycogen synthase kinase 3 (GSK3) and CK2-related protein kinases; FRET

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Tramadol enhances hepatic insulin sensitivity via enhancing insulin signaling cascade in the cerebral cortex and hypothalamus of 90% pancreatectomized rats

Keywords: Dexamethasone; Mu receptor agonist; Serotonin reuptake inhibitor; Cerebral cortex; Hypothalamus; Neuronal cells; CREB; cAMP response element binding protein; CSII; continuous subcutaneous insulin infusion therapy; DEX; dexamethasone; DMEM; Dulbecco's Modi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Human adenosine A3 receptor leads to intracellular Ca2+ mobilization but is insufficient to activate the signaling pathway via phosphoinositide 3-kinase γ in mice

Keywords: A3AR; adenosine A3 receptor; A3ARh/h mice; A3AR-humanized mice; BMMCs; bone marrow-derived mast cells; [Ca2+]i; intracellular Ca2+ concentration; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)adenosine-5′-N-methyluronamide; DT-A; diphtheria toxin A fragment; EP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2?

Keywords: Development and regeneration; Neuronal death; Ara-C; Cytosine arabinoside; BSA; Bovine serum albumin; CaMKIV; Calcium-calmoduline kinase IV; CAPP; Ceramide activated protein phosphatase; cer: c2-ceramide; CREB; CAMP-response element binding protein; ECLEn

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human β-cells from hyperglycemia-induced apoptosis

Keywords: PKB; protein kinase B; FLIP; Fas-associated death domain (FADD)-like interleukin-1β-converting enzyme (FLICE inhibitory protein); cAMP; cyclic adenosine monophosphate; GFP; green fluorescence protein; PBS; phosphate buffered saline; TBST; tris-buffered s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

The conditional kinase ΔMEKK1:ER* selectively activates the JNK pathway and protects against serum withdrawal-induced cell death

Keywords: Bad; Bcl-2 antagonist of cell death; BH; Bcl-2 homology domain; Bim; Bcl-2 interacting modulator; BimEL; Bim extra long; ERK; Extracellular signal-regulated kinase; FBS; Fetal bovine serum; JNK; c-Jun N-terminal kinase; MAPK; Mitogen-activated protein kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

Keywords: Insulin resistance; IRS1; Serine phosphorylation; Kinases; PI 3-kinase; phosphoinositide 3-kinase; Gab1; Grb2-associated binder-1; IRS; insulin receptor substrate; ERK; extracellular signal-regulated kinase; APS; adaptor protein containing PH and SH2 doma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Differential signalling during B-cell maturation

Keywords: BCR; B-cell antigen receptor; DAG; diacylglycerol; GC; germinal centre; IP3; inositol-1,4,5-trisphosphate; ITAM; immunoreceptor tyrosine-based activation motif; ITIM; immunoreceptor tyrosine-based inhibition motif; MAPK; mitogen activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Crystallography for protein kinase drug design: PKA and SRC case studies

Keywords: PKA; Protein kinase A; PIFtide; Phosphoinositide-dependent kinase 1 interacting fragment peptide; CDK2; cyclin-dependent kinase 2; ATP; adenosine triphosphate; PKB; Protein kinase B; PKC; Protein Kinase C; PKG; Protein kinase G; PKI; protein kinase A inhi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists: evidence for disparate functional effects which are independent of NF-κB and PPARγ

Keywords: COX; cyclooxygenase; PPAR; peroxisome proliferator-activated receptor; 15d-PGJ2; 15-deoxy-Δ12,14 prostaglandin J2; HRP; horseradish peroxidase; BADGE; bisphenol A diglycidyl ether; PKB; protein kinase B; mPGES; microsomal prostaglandin E synthase; GSK; g

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Regulatory roles and molecular signaling of TNF family members in osteoclasts

Keywords: AP-1; activator protein-1; ASK1; apoptosis signal-regulated kinase-1; CARD; caspase recruiting domain; CFU-GM; colony forming unit-granulocyte/macrophage; CRD; cysteine-rich repeat; CTR; calcitonin receptor; DD; death domain; DED; death effector domain; E

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Protein kinase structure and function analysis with chemical tools

Keywords: AANAT; serotonin N-acetyltransferase or arylalkylamine N-acetyltransferase; aPP; avian pancreatic polypeptide; CaMKII; Ca2+/calmodulin kinase II; CAT; chloramphenicol acetyltransferase; CHO; Chinese hamster ovary; Csk; C-terminal Src kinase; Fmoc; fluoren

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

The last five amino acid residues at the C-terminus of PRK1/PKN is essential for full lipid responsiveness

Keywords: aPKC; atypical PKC; cPKC; classic PKC, MD molecular dynamics; nPKC; novel PKC; PAGE; polyacrylamide gel electrophoresis; PRK1; protein kinase C-related kinase 1; PKC; protein kinase C; PKA; cAMP-dependent protein kinase; PKB; protein kinase B; PDK-1; 3-ph

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Phosphoinositide 3-kinases can act independently of p27Kip1 to regulate optimal IL-3-dependent cell cycle progression and proliferation

Keywords: BMMC; bone marrow-derived mast cells; CFDA SE; carboxy-fluoroscein diacetate succinimidyl ester; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; ERK; extracellular-regulated kinase; FOXO; Forkhead family transcription factors; G1; Ga

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

PKB mediates c-erbB2-induced epithelial β1 integrin conformational inactivation through Rho-independent F-actin rearrangements

Keywords: ca; constitutively active; dn; dominant-negative; ERK; extracellular signal-regulated kinase; GFP; green fluorescent protein; GST; glutathione-S-transferase; ILK; integrin-linked kinase; LPA; lysophosphatidic acid; LTB; latrunculin B; mDia; mammalian ho

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing

Keywords: AEA; anandamide; DNBS; dinitrobenzene sulphonic acid; ERK; extracellular-regulated kinase; FAAH; fatty acid amide hydrolase; GSK; glycogen synthase kinase; LPA; lysophosphatidic acid; MAPK; mitogen-activated protein kinase; NE; noladin ether; PI3K; phosph

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; AIF; apoptosis-inducing factor; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; APC; adenomatous polyposis coli; APP; amyloid precursor protein; BrdU; bromodeoxyuridine; CARD; cas

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2005 سفارش ترجمه