Preparation of radioiodinated peptide nucleic acids with high specific activity
Keywords: Peptide nucleic acid; PNA; Radiolabeling; Radioiodination; Northern blot
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Detection of a rare oligo(A) repeat tract mutation (8As â 7As) in the sequence encoding the La/SS-B autoantigen
Keywords: Mutation; La autoantigen; PNA; Oligo(A);
RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA
Keywords: Oligonucleotide; Peptide; PNA; siRNA; Tat-dependent trans-activation; Cell delivery
Evaluation of two chelators for labelling a PNA monomer with the fac-[99mTc(CO)3]+ moiety
Keywords: PNA; Antisense; Tricarbonyl; Technetium; Rhenium
Efectos renales y sistémicos en la prevención de la nefrotoxicidad por contraste con sueros salino (0,9%) e hiposalino (0,45%)
Keywords: Nefrotoxicidad por contraste; Salino isotónico; Hiposalino; Volumen plasmático; Osmolalidad; Protección renal; Contrast nephrotoxicity; Isotonic saline; Hypotonic saline; Plasma volume; Osmolality; Renal protection; Crp; creatinina plasmática; FE; fra
Insight into the profibrinolytic activity of dermatan sulfate: Effects on the activation of plasminogen mediated by tissue and urinary plasminogen activators
Keywords: Plm; plasmin; Plg; plasminogen; PA; plasminogen activators; t-PA; tissue plasminogen activator; u-PA; urinary plasminogen activator; DS; dermatan sulfate; GAG; glycosaminoglycan; MW; molecular weight; HC II; heparin cofactor II; EACA; 6-aminohexanoic acid
Lectin binding and effects in culture on human cancer and non-cancer cell lines: Examination of issues of interest in drug design strategies
Keywords: Lectin-derivatized microbeads; CCL-220/Colo320DM; CRL-1459/CCD-18Co; PNA; DBA; Lectin-cell binding;
Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metallo-proteases as well as tyrosine phosphatases
Keywords: PNA; Protease inhibitors; Phosphatase inhibitors; Combinatorial chemistry; Microarrays; CDI; 1,1â²-carbodiimidazole; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DIC; diisopropylcarbodiimide; 4-DMAP; 4-dimethylaminopyridine; DMP; Dess-Martin periodinane; D
Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells
Keywords: Bn; benzyl; ConA; concanavalin A; Gal; galactose; GlcNAc; N-acetylglucosamine; HP; helix pomatia; MAA; Maackia amurensis agglutinin; MALDI; matrix-assisted laser desorption ionization; Man; mannose; MS; mass spectrometry; PHA; phaseolus vulgaris hemagglut
Synthesis of a novel ester analog of nucleic acids bearing a serine backbone
Keywords: Nucleic acid analog; Polyester; Serine; Solid-phase synthesis; Racemization; Condensing reagent; PNA
Mass spectrometric characterization of DNA microarrays as a function of primary ion species
Keywords: DNA; PNA; TOF-SIMS; Biosensor; Microarray; Cluster ions;
Dda helicase unwinds a DNA–PNA chimeric substrate: Evidence for an inchworm mechanism
Keywords: MMT, monomethoxytrityl; DMT, dimethoxytrityl; PNA, peptide nucleic acid; ss, single stranded; ds, double strandedHelicase; Peptide nucleic acids; PNA; DNA–PNA chimera; Unwinding
Identification and biochemical characterization of Leishmania strains isolated in Peru, Mexico, and Spain
Keywords: Leishmania species; In vitro culture; Lectin agglutination: Con A; lectin from Canavalia ensiformis; VV; lectin from Vicia villosa; WGA; lectin from Triticum vulgaris; PNA; lectin from Arachis hypogae; Isoenzyme electrophoresis: ME; malic enzyme [EC 1.1.1
Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates
Keywords: Conjugation; Oligolysine; PNA; Splicing correction; Endocytosis
Comparison of basic peptides- and lipid-based strategies for the delivery of splice correcting oligonucleotides
Keywords: Antisense oligonucleotide; PNA; Delivery; Cell penetrating peptide; Liposome; Splicing correction
Extracellular matrix glycoproteins inhibit neurite outgrowth of different types of identified leech neurons in culture
Keywords: neurite outgrowth; regeneration; extracellular matrix; inhibitory proteins; PNA; leechAE, annulus erector; AP, anterior pagoda; ECM, extracellular matrix; PNA, peanut
The 'fully protected backbone' approach as a versatile tool for a new solid-phase PNA synthesis strategy
Keywords: PNA; Solid-phase synthesis; FPB strategy;
Synthesis and oligodeoxynucleotide binding properties of pyrrolidinyl peptide nucleic acids bearing prolyl-2-aminocyclopentanecarboxylic acid (ACPC) backbones
Keywords: β-Amino acid; DNA; PNA; Binding; Hybridization; Proline; Foldamer;
Avian thymic hormone treatment of peripheral blood mononuclear cells from young chicks stimulates acute graft-versus-host reaction in chicken embryos
Keywords: ATH; avian thymic hormone; CAM; chorioallantoic membrane; CTL; cytotoxic T lymphocyte; FBS; foetal bovine serum; GVHR; graft-versus-host reaction; PBMC; peripheral blood mononuclear cells; PHA; phytohaemagglutinin; PNA; peanut agglutinin; NK cell; natural
DNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles
Keywords: DNA; PNA; Nanoassemblies; DNA-gold nanoparticle interactions;
Structural and functional characterization of self-assembled monolayers of peptide nucleic acids and its interaction with complementary DNA
Keywords: Biosensor; DNA; Self-assembling; PNA;
FISH and immunocytochemistry: towards visualising single target molecules in living cells
Keywords: FISH; fluorescence in situ hybridization; FRET; fluorescence resonance energy transfer; IC; immunocytochemistry; PNA; peptide nucleic acid; QD; quantum dot;
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes
Keywords: GC; germinal center; BCR; B cell receptor; GEF; guanine nucleotide exchange factor; CDM; CED-5, DOCK180, Myoblast city; CZH; CDM-zizimin homology; GFP; green fluorescence protein; PNA; peanuts agglutinin; PH; pleckstrin homology; GST; glutathione S-transf
The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy
Keywords: Peanut anaphylaxis; Chinese herbal medicine formula; TH2 cytokine modulation; BUN; Blood urea nitrogen; CBC; Complete blood cell count; ConA; Concanavalin A; FAHF; Food allergy herbal formula; PNA; Peanut allergy;
Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice
Keywords: AA; ambient air; DSFC; dorsal skin-fold chamber; dsDNA; double stranded DNA; EDTA; ethylenediaminetetraacetate; EMSA; electrophoretic mobility-shift assay; HEPES; N-2-hydroxyethylpiperazine-N-2-ethanesulfonic acid; HR; hypoxia-reoxygenation; ICAM-1; inter
Advantages of peptide nucleic acid oligonucleotides for sensitive site directed 16S rRNA fluorescence in situ hybridization (FISH) detection of Campylobacter jejuni, Campylobacter coli and Campylobacter lari
Keywords: Campylobacter; FISH; Hybridization; PNA; Probe;
A chymotrypsin-like proteinase from the midgut of Tenebrio molitor larvae
Keywords: Chymotrypsin; Digestive proteinase; Midgut; Tenebrio molitor; Yellow mealworm; Ac; acetyl; AM; anterior midgut; Bz; benzoyl; DMF; dimethyl formamide; E-64; l-trans-epoxysuccinyl-l-leucylamido(4-guanidino) butane; Glp; pyroglutamyl; PM; posterior midgut; P
Flow cytometric assessment of Leishmania spp metacyclic differentiation: Validation by morphological features and specific markers
Keywords: Trypanosomatid parasitic protozoa; Metacyclic promastigotes; Metacyclogenesis; LPG; lipophosphoglycan; PNA; peanut agglutinin; BPL; Bauhinia purpurea lectin; FCM; flow cytometry; FSC; forward-angle light scatter; SSC; side-angle light scatter; mAb; monocl
Non-aqueous nanofiltration: solute rejection in low-polarity binary systems
Keywords: Nanofiltration; Membrane; PDMS; Non-aqueous; Solute rejection; Polymer swelling; Filtration; Organometallic; PNA;
Development of a peptide nucleic acid polymerase chain reaction clamping assay for semiquantitative evaluation of genetically modified organism content in food
Keywords: PCR clamping; PNA; GMO traceability; Maize; Soybean;
Electrochemical activity of new ferrocene-labelled PNA monomers to be applied for DNA detection: Effects of the molecular structure and of the solvent
Keywords: DNA detection; PNA; Ferrocene; Electrochemically active markers; Reversible outer-sphere electron transfer; Molecular structure effect; Medium effect;
Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)
Keywords: DPP; dipeptidyl-peptidase; GLP-1; glucagon-like peptide-1; GIP; glucose-dependent insulinotropic polypeptide; PO; prolyl oligopeptidase; pNA; para-nitroaniline; DTT; dithiothreitol; Dipeptidyl-peptidase IV; LAF237; GLP-1; GIP; Substance P; Protease inhibi
Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease
Keywords: TEMPOL; 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl; PNA; polynitroxylated albumin; DOPAC; dihydroxyphenylacetic acid; HVA; homovanilic acid; TH; tyrosine hydroxylase; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-te
Membrane destabilizing properties of cell-penetrating peptides
Keywords: CF; 5- (and 6-) carboxyfluorescein; CHO; Chinese hamster ovary; CPP; cell-penetrating peptide; DPPG; 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocoline; DOPG; 1,2-dioleoyl-sn-glycero-3-phosphoglycerol; DSPE-PEG; 1,
Dde-protected PNA monomers, orthogonal to Fmoc, for the synthesis of PNA-peptide conjugates
Keywords: PNA; Dde; Fmoc; Orthogonality; Conjugate; Peptide;
Hypoxia-reoxygenation-induced mitochondrial damage and apoptosis in human endothelial cells are inhibited by vitamin C
Keywords: H-R; hypoxia-reoxygenation; ROS; reactive oxygen species; DCFH-DA, 2â²,7â²; dichlorodihydrofluorescein diacetate; Cyt C; cytochrome C; DAPI; (4â²,6â²-diamidino-2-phenylindole); HUVEC; human umbilical vein endothelial cells; HCAEC; human coronary arter
Possible mechanisms underlying copper-induced damage in biological membranes leading to cellular toxicity
Keywords: MDA; malondialdehyde; DTNB; 5,5â²-dithio-bis (2-nitrobenzoic) acid; GSH; glutathione; TCA; trichloroacetic acid; EDTA; ethylene-diamino-tetra-acetic acid; NEM; N-ethyl-maleimide; PNA; p-nitroanisole; TBA; 2-thiobarbituric acid; TBARS; thiobarbituric acid
Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery
Keywords: Antp; penetratin peptide from Antennapaedia; CPP; cell penetrating peptide; ELP; elastin-like polypeptide; MβCD; methyl-β-cyclodextrin; MTS; membrane translocating sequence from Kaposi fibroblast growth factor; PBS; phosphate buffered saline; PNA; pepti
Lipophilic peptide nucleic acids containing a 1,3-diyne function: synthesis, characterization and production of derived polydiacetylene liposomes
Keywords: Nucleic acid biosensors; PNA; Polydiacetylenes; Liposomes;
Plant serine proteases: biochemical, physiological and molecular features
Keywords: Enzyme; Mechanism; Substrate specificity; Function; Clp; chloroplast protease; DFP; diisopropylfluorophosphate; HR; hypersensitive response; PCD; programmed cell death; PMSF; phenylmethylsulfonylfluoride; pNA; para-nitroanilide; TE; tracheary element;
Distinct binding patterns of fucose-specific lectins from Biomphalaria alexandrina and Lotus tetragonolobus to murine lymphocyte subsets
Keywords: Fucosylated; Glycoconjugates; Lectin; BaSI; Biomphalaria alexandrina lectin; BSA; bovine serum albumin; L. tetragonolobus; Lotus tetragonolobus; mAb; monoclonal antibody; PNA; peanut agglutinin;
The selective expression of distinct fucosylated glycoproteins on murine T and B lymphocyte subsets
Keywords: Anguilla anguilla agglutinin; Fucosylated determinants; Splenocytes; Thymocytes; Ulex europaeus agglutinin; AAA; Anguilla anguilla agglutinin; BSA; Bovine serum albumin; mAb; Monoclonal antibody; PALS; Periarteriolar lymphoid sheath; PNA; Peanut agglutini
Recent climate change in the Arctic and its impact on contaminant pathways and interpretation of temporal trend data
Keywords: AO; Arctic Oscillation; DDT; dichlorodiphenyltrichloroethane; ENSO; El Niño-Southern Oscillation; GHG; greenhouse gases; HCB; hexachlorobenzene; HCH; hexachlorocyclohexane; HLC; Henry's Law Constant; IABP; International Arctic Buoy Programme; IPCC; Int