Keywords: پیچک سرکوبگر پلی کامب 2; Histone methylation; Histone demethylation; Lung cancer; Histone methyltransferase; Histone demethylase; Inhibitors; ALK; anaplastic lymphoma kinase; DUSP3; dual-specificity phosphatase 3; Elk1; ETS-domain containing protein; EMT; epithelial-to-mesenchyma
مقالات ISI پیچک سرکوبگر پلی کامب 2 (ترجمه نشده)
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Keywords: پیچک سرکوبگر پلی کامب 2; CT; computed tomography; IV; intravenous; PET; Positron Emission Tomography; Gy; gray; PRC2; polycomb repressive complex 2; Myoepithelial carcinoma; Epithelioid sarcoma; SMARCB1 deficiency; EZH2 inhibitor; Case report;
Keywords: پیچک سرکوبگر پلی کامب 2; ChEA; Chip-Enrichment Analysis; DEGs; differentially expressed gene; DE-TFs; differentially expressed TFs; ECs; epithelial-like cells; iNs; induced neurons; iNSCs; induced neural stem cells; NRPCs; neural restricted progenitor cells; NSCs; neural stem cel
Keywords: پیچک سرکوبگر پلی کامب 2; ACVR1; Activin A receptor type1; ATRX; A-thalassemia/mental retardation syndrome X-linked; BMP; Bone morphogenetic protein; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CNS; Central nervous system; DAXX; Death domain-associated protein; DNMT; DNA
Keywords: پیچک سرکوبگر پلی کامب 2; ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a
Keywords: پیچک سرکوبگر پلی کامب 2; CAPRI; Ca2+-promoted RAS inactivator; CRMP-2; collapsin response mediator protein-2; CSRD; cysteine/serine-rich domain; CTD; C-terminal domain; ERK; extracellular signal-regulated kinase; FTI; farnesyltransferase inhibitor; FAK1; focal adhesion kinase 1;
Keywords: پیچک سرکوبگر پلی کامب 2; 5-aza-CdR; 5-aza-2â²-deoxycytidine; AML; acute myeloid leukemia; ANRIL; antisense non-coding RNA in the INK4 locus; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CoREST; co-repressor for element-1-silencing transcription factor
Keywords: پیچک سرکوبگر پلی کامب 2; α-KG; alpha-ketoglutarate; 2-HG; 2-hydroxyglutarate; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; ASXL1; additional sex combs-like 1; AZA; azacytidine; CMML; chronic myelomonocytic leukemia; DAC; decitabine; DNMT3A;
Keywords: پیچک سرکوبگر پلی کامب 2; lncRNA; long/large noncoding RNA; Xist; X-inactive specific transcript; mESC; mouse embryonic stem cell; Evf2; embryonic ventral forebrain 2; Six3os; sine oculis-related homeobox 3 homolog, opposite strand; Dlx1as; distal-less homeobox 1, antisense; EGO;
LncRNA HOXA-AS2 and its molecular mechanisms in human cancer
Keywords: پیچک سرکوبگر پلی کامب 2; lncRNA; HOXA-AS2; Diagnosis; Therapeutic target; Prognosis; APL; Acute promyelocytic leukemia; ATRA; All trans retinoic acid; Bax; BCL2-Associated X; BC; Breast cancer; Bcl-2; B-cell lymphoma-2; c-Myc; MYC proto-oncogene; CRC; Colorectal cancer; DDIT3; DN
Immunohistochemical evaluation of H3K27 trimethylation in malignant peripheral nerve sheath tumors
Keywords: پیچک سرکوبگر پلی کامب 2; Malignant peripheral nerve sheath tumor; H3K27me3; Neurofibromatosis type 1; Polycomb repressive complex 2; Heterochronous;
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis
Keywords: پیچک سرکوبگر پلی کامب 2; carnosol (PubChem CID:442009); resveratrol (PubChem CID:445154); DZNep; 3-Deazaneplanoci A; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CS; carnosol; CCl4; carbon tetrachloride; H3K27me3; catalyzes trimethylation of lysine 27 on histon
Polymorphisms in non-coding RNAs and risk of colorectal cancer: A systematic review and meta-analysis
Keywords: پیچک سرکوبگر پلی کامب 2; SNP; single nucleotide polymorphism; HOTAIR; HOX transcript antisense RNA; PRC2; polycomb repressive complex 2; H3K27; 27th amino acid in Histone H3; LncRNAs; long non-coding RNAs; PFS; progression-free survival; TTP; thrombotic thrombocytopenic purpura;
MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma
Keywords: پیچک سرکوبگر پلی کامب 2; c-Myc/EZH2 double positive; microRNA-26a; Epigenetics modification; Metastasis; Advanced hepatocellular carcinoma; AAV; adeno-associated virus; CDK8; cyclin dependent kinase 8; CTDSP2; CTD small phosphatase 2; DEN; diethylnitrosamine; DZNep; 3-deazaneplan
Interactions between microRNAs and long non-coding RNAs in cardiac development and repair
Keywords: پیچک سرکوبگر پلی کامب 2; AAV; adeno-associated virus; AMI; acute myocardial infarction; APF; autophagy promoting factor; Bvht; Braveheart; CARL/Carl; cardiac apoptosis-related lncRNA; CARMEN/Carmen; cardiac mesoderm enhancer-associated non-coding RNA; CHAER/Chaer; cardiac-hypertr
Dual Role of EZH2 in Cutaneous Anaplastic Large Cell Lymphoma: Promoting Tumor Cell Survival and Regulating Tumor Microenvironment
Keywords: پیچک سرکوبگر پلی کامب 2; CD30+LPD; CD30+ lymphoproliferative disease; CTCL; cutaneous T-cell lymphoma; CXCL10; C-X-C motif chemokine ligand 10; CXCR3; C-X-C motif chemokine receptor 3; EZH2; enhancer of zeste homolog; H3K27me3; histone H3 lysine 27 trimethylation; LCT; large-cell
YAP promotes breast cancer metastasis by repressing growth differentiation factor-15
Keywords: پیچک سرکوبگر پلی کامب 2; ALPP; alkaline phosphatase; AREG; amphiregulin; α-SMA; alpha smooth muscle actin; BIRC5; baculoviral inhibitor of apoptosis repeat-containing 5; ChIP; chromatin immunoprecipitation; CTGF; connective tissue growth factor; DDIT4; DNA-damage inducible trans
BMI1 and PTEN are key determinants of breast cancer therapy: A plausible therapeutic target in breast cancer
Keywords: پیچک سرکوبگر پلی کامب 2; HDAC i; histone deacetylase inhibitors; PcG; polycomb group; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; Bmi1; B lymphoma Mo-MLV insertion region homolog; EMT; epithelial to mesenchymal transition; PTEN; phosphatase and tensi
HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo
Keywords: پیچک سرکوبگر پلی کامب 2; PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM
Overexpression of dJmj differentially affects intestinal stem cells and differentiated enterocytes
Keywords: پیچک سرکوبگر پلی کامب 2; ISCs; intestinal stem cells; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; PRC2; Polycomb repressive complex 2; H3K27me3; tri-methylation of lysine 27 of histone H3; Su(H); suppressor of hairless; Pdm1; POU-domain transcription factor;
EZH2-mediated α-actin methylation needs lncRNA TUG1, and promotes the cortex cytoskeleton formation in VSMCs
Keywords: پیچک سرکوبگر پلی کامب 2; LncRNAs; long non-coding RNAs; TUG1; taurine up-regulated gene 1; VSMCs; vascular smooth muscle cells; SENCR; smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA; Ang II; angiotensin II; PRC2; polycomb repr
Split luciferase-based biosensors for characterizing EED binders
Keywords: پیچک سرکوبگر پلی کامب 2; PRC2; EED; H3K27me3-pocket; Split luciferase; Biosensor; EED[G255D]; EED; embryonic ectoderm development; PRC2; polycomb repressive complex 2; DSF; differential scanning fluorimetry; ITC; isothermal titration calorimetry; EZH2; enhancer of zeste homolog 2
Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway
Keywords: پیچک سرکوبگر پلی کامب 2; SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle
Compositional and functional diversity of canonical PRC1 complexes in mammals
Keywords: پیچک سرکوبگر پلی کامب 2; bps; base pairs; PcG; Polycomb Group; PRC1; Polycomb Repressive Complex 1; PRC2; Polycomb Repressive Complex 2; Pc; Polycomb; Ph; Polyhomeotic; Psc; Posterior sex combs; Sce; Sex combs extra; H3K27me3; histone H3 lysine 27 trimethylation; SAM; sterile alp
Epigenetics during EMT in lung cancer: EZH2 as a potential therapeutic target
Keywords: پیچک سرکوبگر پلی کامب 2; EMT; Epigenetics; Polycomb Repressive Complex 2; SWI/SNF; NSCLC; SCLC; SETD2; chromatin modifications;
Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver
Keywords: پیچک سرکوبگر پلی کامب 2; Hotair; LncRNA HOX transcript antisense RNA; HSCs; hepatic stellate cells; PRC2; polycomb repressive complex 2; H3K27me3; histone H3-lysine27; DNMT1; DNA methyltransferase 1; α-SMA; alpha smooth muscle actin; Col1a1; alpha1(1) collagen; NcRNA; non-coding
MicroRNAs: New regulators of IL-22
Keywords: پیچک سرکوبگر پلی کامب 2; IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Steroid receptor RNA activator: Biologic function and role in disease
Keywords: پیچک سرکوبگر پلی کامب 2; AF-2; activation function-2; AR; androgen receptor; C/EBPα; ccaat-enhancer-binding protein α; CTCF; CCCTC-binding factor; Ddx5; DEAD box protein 5; ERα; estrogen receptor α; GR; glucocorticoid receptor; Hes1; hairy and enhancer of split-1; HP1γ; hete
Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development
Keywords: پیچک سرکوبگر پلی کامب 2; FACS; fluorescence-activated cell-sorting; Krt; keratin; PRC2; polycomb repressive complex 2; RT-qPCR; semiquantitative real-time PCR;
Long noncoding RNAs: Lessons from genomic imprinting
Keywords: پیچک سرکوبگر پلی کامب 2; lncRNA; long noncoding RNA; DMR; Differentially methylated region; ICR; Imprinting control region; PWS; Prader-Willi syndrome; AS; Angelmann syndrome; MEGs; Maternally expressed genes; TTS; Triplex target sites; TFO; Triplex forming oligo; IG-DMR; Inter
Non-coding RNAs in gastric cancer
Keywords: پیچک سرکوبگر پلی کامب 2; ncRNAs; non-coding RNAs; sncRNAs; small ncRNAs; lncRNAs; long ncRNAs; snoRNAs; small nucleolar RNAs; piRNAs; Piwi-associated RNAs; miRNAs; microRNAs; tiRNAs; transcription initiation RNAs; lincRNAs; long intergenic ncRNAs; GC; gastric cancer; nts; nucleot
AEBP2 as a transcriptional activator and its role in cell migration
Keywords: پیچک سرکوبگر پلی کامب 2; Aebp2; Polycomb Repressive Complex 2; Cell migration; Neural crest cells
Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells
Keywords: پیچک سرکوبگر پلی کامب 2; IGF2 imprinting; SUZ12; Intrachromosomal loop; Histone K27 methylation; Epigenetics; CTCF; Promoter; Polycomb repressive complex 2
Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus
Keywords: پیچک سرکوبگر پلی کامب 2; PcG; polycomb group; EZH2; enhancer of zeste homolog 2; shRNA; short hairpin RNA; Rb; retinoblastoma; MDM2; murine double minute 2; CDKIs; cyclin-dependent kinase inhibitors; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; H3K27m
Polycomb recruitment at the Class II transactivator gene
Keywords: پیچک سرکوبگر پلی کامب 2; PRC2; polycomb repressive complex 2; EZH2; enhancer of zeste homolog 2; JARID2; jumonji, AT rich interactive domain 2; YY1; Yin-Yang 1; CIITA pIV; class II transactivator promoter IV; MHC; major histocompatibility complex; lncRNA; long non-coding RNA; HOT
Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives
Keywords: پیچک سرکوبگر پلی کامب 2; C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo
Long noncoding RNAs: Novel insights into gastric cancer
Keywords: پیچک سرکوبگر پلی کامب 2; ABHD11-AS1; antisense RNA 1; ANRIL; CDKN2B antisense RNA 1; EMT; epithelial-mesenchymal transition; FER1L4; Fer-1-like protein 4; GACAT1; gastric cancer-associated transcript 1; GC; gastric cancer; HOTAIR; HOX transcript antisense RNA; LncRNA; long non-
Research ArticleA CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients
Keywords: پیچک سرکوبگر پلی کامب 2; HCC; hepatocellular carcinoma; HBV; hepatitis B virus; E2F1; E2F transcription factor 1; EZH2; enhancer of zeste homolog 2; PRC2; polycomb repressive complex 2; H3K27me3; trimethylation of lysine 27 at histone H3; AR; androgen receptor; CCRK; cell cycle-r
WTIP interacts with ASXL2 and blocks ASXL2-mediated activation of retinoic acid signaling
Keywords: پیچک سرکوبگر پلی کامب 2; Asx; additional sex comb; ASXH; Asx-homology; ASXL; additional sex comb-like; ATRA; all trans-retinoic acid; HARE-HTH; HARE helix-turn-helix; H3K27me3; trimethylated histone H3 lysine 27; NR; nuclear receptor; PHD; plant homeodomain; PRC2; Polycomb repres
A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival
Keywords: پیچک سرکوبگر پلی کامب 2; lncRNA; long noncoding RNA; Sox2ot; Sox2 overlapping transcript; SCC; squamous cell carcinoma; ADC; adenocarcinoma; NSCLC; non-small cell lung cancer; EZH2; enhancer of zeste homolog 2; PRC2; polycomb repressive complex 2; MALAT1; metastasis-associated lu
TAF13 interacts with PRC2 members and is essential for Arabidopsis seed development
Keywords: پیچک سرکوبگر پلی کامب 2; Seed; Arabidopsis; Polycomb Repressive Complex 2; Endosperm; Gene regulation;
Enhancer of Zeste Homolog 2 Silences MicroRNA-218 in Human Pancreatic Ductal Adenocarcinoma Cells by Inducing Formation of Heterochromatin
Keywords: پیچک سرکوبگر پلی کامب 2; Pancreatic Cancer; Gene Regulation; Epigenetic; Messenger RNA Processing; 3â²-UTR; 3â²-untranslated region; 5AZAC; 5-azacytidine; DNMT; DNA methyltransferase; DZnep; 3-deazaneplanocin A; EZH2; enhancer of zeste 2 homolog; H3K27me3; histone 3 lysine 27 t
A687V EZH2 is a gain-of-function mutation found in lymphoma patients
Keywords: پیچک سرکوبگر پلی کامب 2; DLBCL; diffuse large B-cell lymphoma; CPM; counts per minute; GCB; germinal Center B-cell-like; H3K27; histone H3 lysine 27; NHL; non-Hogdkin lymphoma; PKMT; protein lysine methyltransferase; PRC2; Polycomb Repressive Complex 2; SAM; S-adenosylmethionine;