مقالات ISI (ترجمه نشده)
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Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands
Keywords: Nuclear receptor ligands; FXR; PPAR; Drug design; Diphenylmethane
Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs
Keywords: Thiazoles; Stille reactions; Suzuki reactions; Nuclear receptors; PPAR
Effects of interleukin-15 on lipid oxidation: Disposal of an oral [14C]-triolein load
Keywords: IL-15; Lipid metabolism; Skeletal muscle; Liver; PPAR
The Impact of Increased Body Mass Index on the Clinical Course of Crohn's Disease
Keywords: BMI; body mass index; CD; Crohn's disease; CI; confidence interval; IBD; inflammatory bowel disease; PPAR; peroxisome proliferator activated receptor;
Diabetes: Assessing the pipeline
Keywords: Type 2 diabetes; Metabolic syndrome; Cardiovascular complications; GLP-1; Amylin; PPAR; Endocannabinoid
Peroxisome proliferator-activated receptor agonist regulation of glial activation: Relevance to CNS inflammatory disorders
Keywords: Microglia; Astrocyte; PPAR; Cytokine; Neuroinflammation
Inflammatory modulation of PPARγ expression and activity
Keywords: NO, nitric oxide; iNOS, inducible nitric oxide synthase; PPAR, peroxisome proliferation receptorLupus; Nitric oxide; Inflammation; PPAR; iNOS; MRL/lpr
Ageing introduces a complex pattern of changes in several rat brain transcription factors depending on gender and anatomical localization
Keywords: Cortex; Hippocampus; Aged rat; NFκB; AP-1; LXR; PPAR;
Antipsychotic induced metabolic abnormalities: An interaction study with various PPAR modulators in mice
Keywords: Clozapine; Ziprasidone; Hyperglycemia; Dyslipidemia; PPAR;
Dual PPAR-α and -γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential
Keywords: PPAR; TZD; Knoevenagel condensation; Plasma glucose; Lipids
Identification of a truncated alternative splicing variant of human PPARγ1 that exhibits dominant negative activity
Keywords: PPAR; Alternative splicing; Dominant negative activity; Cell proliferation; Clonogenic ability
Expression patterns of the chicken peroxisome proliferator-activated receptors (PPARs) during the development of the digestive organs
Keywords: PPAR; Chicken; Digestive organs; Development
PPAR-γ ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells
Keywords: PPAR; Amino acid; Apoptosis; Melanoma; Breast cancer; Prostate cancer
Differentiation and growth inhibition mediated via the RXR:PPARγ heterodimer in colon cancer
Keywords: Colon cancer; RXR; PPAR; Differentiation induction; Growth inhibitionPPARγ, peroxisome proliferator activated receptor gamma; RXR, retinoid x receptor; PPRE, a peroxisome proliferator activated receptor hormone response element; COX-2, prostaglandin-endop
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARδ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
Keywords: Methionine-choline-deficient diet; NASH; Bezafibrate; PPAR; GW501516; (Mouse)
Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications
Keywords: PPAR; Arteries; Endothelium; Heart; Inflammation
The role of tumor necrosis factor α and the peroxisome proliferator-activated receptor α in modulating the effects of fumonisin in mouse liver
Keywords: H&E; hematoxylin and eosin; PPAR; peroxisome proliferator-activated receptor; PP; peroxisome proliferator; TNF; tumor necrosis factor; WY; WY-14,643; Peroxisome proliferator-activated receptor α; Fumonisin; Tumor necrosis factor α; Apoptosis; Hepatocyte
Effects of 3-thia fatty acids on expression of some lipid related genes in Atlantic salmon (Salmo salar L.)
Keywords: Apolipoproteins; Atlantic salmon; Dodecylthioacetic acid; Fatty acids; PPAR; Real-Time PCR; Scavenger receptor; Tetradecylthioacetic acid
Effect of dietary conjugated linoleic acid (CLA) on lipid composition, metabolism and gene expression in Atlantic salmon (Salmo salar) tissues
Keywords: CLA; PPAR; β-oxidation; Fatty acid; Desaturation; Elongation; Atlantic salmon
Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors α and γ in breast
Keywords: MEHP; MBP; PPAR; Human; Breast
Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis
Keywords: Diethylhexyl phthalate; Phthalates; Anti-androgen; Prenatal; Steroid synthesis; Testosterone; PPAR; SF-1
Fatty acid elongases in mammals: Their regulation and roles in metabolism
Keywords: ACC; acetyl-CoA carboxylase; BAT; brown adipose tissue; CIG30; cold induced glycoprotein of 30Â kDa; CNS; central nervous system; DGAT; diacylglycerol acyltransferase; DHA; docosahexaenoic acid; Elo; yeast elongase; ELOVL; elongation of very long chain fa
Evolutionary relationship and substrate specificity of Arabidopsis thaliana fatty acid omega-hydroxylase
Keywords: AOS; allene oxide synthase; AT; acyltransferase; BSTFA; bis(trimethylsilyl) trifluoroacetamide; DAGAT; diacylglycerol acyltransferase; C12:0; lauric acid; C14:0; myristic acid; C16:0; palmitic acid; C18:1; oleic acid; CoA; coenzyme A; CYP, P450; cytochrom
Peroxisome proliferator-activated receptors: Bridging metabolic syndrome with molecular nutrition
Keywords: PPAR; Inflammation; Adipocyte hypertrophy; Obesity; Metabolic syndrome
Cellular, Molecular Consequences of Peroxisome Proliferator- Activated Receptor-δ Activation in Ovarian Cancer Cells
Keywords: Peroxisome proliferator-activated receptor δ; ovarian cancer; nuclear receptor; gene expression profiling; thiazolidinediones; EOC; epithelial ovarian cancer; FBS; fetal bovine serum; MTT; 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide; PP
Inflammation and immune regulation by 12/15-lipoxygenases
Keywords: IL; interleukin; PPAR; peroxisomal proliferator-activataing receptor; SP-HPLC; straight phase high pressure liquid chromatography; H(p)ODE; hydro(pero)xyoctadecadienoic acid; H(p)ETE; hydro(pero)xyeicosatetraenoic acid; LOX; lipoxygenase; LDL; low density
Putative function and physiological relevance of the mitochondrial uncoupling protein-3: Involvement in fatty acid metabolism?
Keywords: ACS; acyl-CoA synthase; BAT; brown adipose tissue; CPT; carnitine palmitoyltransferase; CRE; cyclic AMP response element; DNP; 2,4-dinitrophenol; FCCP; carbonylcyanide p-trifluoromethoxyphenylhydrazone (an uncoupling reagent); KO; knock-out (animals); MEF
Selective PPARγ modulators with improved pharmacological profiles
Keywords: PPAR; Selective modulator; Partial agonists
Regulatory role of peroxisome proliferator-activated receptor delta (PPARδ) in muscle metabolism. A new target for metabolic syndrome treatment?
Keywords: PPAR; Fatty acid; Obesity; Type 2 diabetes; Metabolic syndrome;
Obesity and NASH in Japan
Keywords: NASH; Prevalence; Fatty liver; Histology; Adipocytokine; HsCRP; PPAR;
Lithium inhibits brown adipocyte differentiation
Keywords: UCP-1; uncoupling protein 1; CO; cytochrome c oxidase; PPAR; peroxisome proliferating activated receptor; PGC-1α; PPAR gamma coactivator-1α; Lithium; Brown adipocyte; Uncoupling protein; Mitochondrion;
Drug-eluting stents for diabetes mellitus
Keywords: BMS; bare-metal stent; DES; drug-eluting stents; ISAR-STEREO; Intracoronary Stenting and Angiographic Results-Strut Thickness Effect on Restenosis Outcomes trial; PCI; percutaneous coronary intervention; PES; paclitaxel-eluting stent; PPAR; peroxisome pro
Roles of PPAR delta in lipid absorption and metabolism: a new target for the treatment of type 2 diabetes
Keywords: PPAR; Fatty acid; Obesity; Type 2 diabetes; Metabolic syndrome;
(2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents
Keywords: PPAR; Chromane-2-carboxylic acid; Atherosclerosis
6-Aryl-4-methylsulfanyl-2H-pyran-2-one-3-carbonitriles as PPAR-γ activators
Keywords: Diabetes; PPAR; Pyran-2-one; Transactivation
Hormone regulation of microglial cell activation: relevance to multiple sclerosis
Keywords: Disorders of the nervous system; Degenerative disease: other; Microglia; Hormone; PPAR; Cytokine; Nitric oxide; Multiple sclerosis;
Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers for Prevention of Type 2 Diabetes
Keywords: ACE; angiotensin-converting enzyme; ARB; angiotensin receptor blocker; PPAR; peroxisome proliferator-activated receptor; RAAS; renin angiotensin aldosterone system;
¿Actúan las estatinas a través de los PPARα?
Keywords: Estatinas; PPAR; NF-κB; Efectos pleieotrópicos; Statins; PPAR; NF-κB; Pleieotropic effects;
Benzoyl 2-methyl indoles as selective PPARγ modulators
Keywords: PPAR; Indole; Selective PPAR modulator;
Regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor
Keywords: PDK4; Glucocorticoids; PPAR; TRB-3; FOXO; Bile acids; Diabetes; Lipid; Glucose;
The metabolic syndrome and the hepatic fatty acid drainage hypothesis
Keywords: Fatty acids; Glucose; Insulin resistance; Metabolic syndrome; TTA; CPT; carnitine palmitoyltransferase; HDL; high density lipoprotein; HMG; 3-hydroxymethyl glutaryl; LPL; lipoprotein lipase; LDL; low density lipoprotein; PPAR; peroxisome-proliferator acti
Proposed involvement of adipocyte glyceroneogenesis and phosphoenolpyruvate carboxykinase in the metabolic syndrome
Keywords: Type 2 diabetes; Adipose tissue; PPAR; Glitazone; Rexinoid; PEPCK; FA; Fatty acid; HbA1c; glycosylated hemoglobin A1c; C/EBP; CCAAT enhancer binding protein; DR1; direct repeat one; NEFA; non-esterified fatty acids; PEPCK-C; cytosolic phosphoenolpyruvate
Phosphorylation of PPARs: from molecular characterization to physiological relevance
Keywords: PPAR; Transcriptional activity; Phosphorylation and kinases; AMPK: AMP-activated protein kinase; ERK: extracellular signal-regulated kinase; JNK: c-Jun N terminal kinase; MAPK: mitogen-activated protein kinase; PKA: cAMP-dependent protein kinase; PKC: cal
Expression of Perilipin A on the Surface of Lipid Droplets Increases along with the Differentiation of Hamster Sebocytes In Vivo and In Vitro
Keywords: insulin; lipogenesis; perilipin; PPAR; sebaceous glands;
Expression and activation of peroxisome proliferator-activated receptors in growth plate chondrocytes
Keywords: Chondrocyte; Growth plate; Thyroid hormone; Peroxisome proliferator activated receptors; PPAR;
Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression
Keywords: global ischemia; CA1 hippocampus; oxygen-glucose deprivation; BV2 microglia; neuroprotection; rat; BV2; immortalized murine cell line; DMEM; Dulbecco's modified eagle's medium; HC2S2; immortalized neuronal progenitor cell line; IL-1ra; IL-1 receptor a
Pulmonary Hypertension
Keywords: HHV; human herpes virus; PPAR; peroxisome proliferator-activated receptor; rVEGF165; recombinant vascular endothelial growth factor; VEGF; vascular endothelial growth factor;
The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium
Keywords: CNBP; cellular nucleic acid-binding protein; CPB; cardiopulmonary bypass; DUSP; dual-specificity phosphatase; FABP; fatty acid-binding protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HADHSC; l-3-hydroxyacyl-CoA dehydrogenase; HSP; heat shock
Identification and organ expression of peroxisome proliferator activated receptors in brown trout (Salmo trutta f. fario)
Keywords: Peroxisome; PPAR; Expression; Teleost;