Expression of PTHrP and PTH/PTHrP receptor 1 in the superior cervical ganglia of rats
Keywords: Superior cervical ganglion; PTHrP; PTHR1; Ovariectomy
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Contribution of PTHrP to mechanical strain-induced fibrochondrogenic differentiation in entheses of Achilles tendon of miniature pigs
Keywords: Entheses; Mechanical strain; Cyclic tensile strain; Ihh; PTHrP; Fibrochondrocytes;
MiR-126-5p regulates osteolysis formation and stromal cell proliferation in giant cell tumor through inhibition of PTHrP
Keywords: PTHrP; miR-126-5p; Giant cell tumor; Osteolysis; Osteoclast differentiation;
In vitro microenvironments to study breast cancer bone colonisation
Keywords: 2D; two-dimensional; 3D; three-dimensional; BSP; bone sialoprotein; COL; collagen; FN; fibronectin; IL; interleukins; ECM; extracellular matrix; OPN; osteopontin; PGE2; prostaglandin E2; PTHrP; parathyroid hormone related protein; RGD; arginine-glycineâ
SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD
Keywords: ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi
Ser/Thr-phosphoprotein phosphatases in chondrogenesis: neglected components of a two-player game
Keywords: ADAMTS; A Disintegrin And Metalloproteinase with Thrombospondin Motifs; BMP; bone morphogenic protein; CaMK; Ca2Â +/calmodulin-dependent protein kinase; CaN; calcineurin; CNA, CNB; calcineurin catalytic (A) and regulatory (B) subunits; COX; cyclooxygenase
Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment
Keywords: Betulinic acid; Osteolytic bone metastasis; PTHrP; RANKL; Osteoclastogenesis; Estrogen deficiency
Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress
Keywords: PTHrP; Caco-2 cell; Apoptosis; MAPK; AKT;
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease
Keywords: BPs; bisphosphonates; ZOL; zoledronate; RANKL; receptor activator of nuclear factor-κB ligand; NTx; N-terminal telopeptide; CATK; cathepsin K; OPG; osteoprotegerin; PTHrP; parathyroid hormone-related peptide; M-CSF; macrophage colony-stimulating factor;
Calcium homeostasis in a patient with hypoparathyroidism during pregnancy, lactation and menstruation
Keywords: Calcium; Hypoparathyroidism; Lactation; Pregnancy; PTHrP
The Ihh signal is essential for regulating proliferation and hypertrophy of cultured chicken chondrocytes
Keywords: Indian hedgehog; Ihh signal; PTHrP; Cyclopamine; Chondrocytes
Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies
Keywords: PTH; PTHrP; Bone formation; Bone repair; Bone anabolic therapyBMPs, bone morphogenetic proteins; BMU, basic multicellular unit; ERKs, extracellular signal-regulated kinases; FGF-2, basic fibroblast growth factor-2; FoxO, forkhead box O; IGFs, insulin-like
Parathyroid hormone–related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2
Keywords: apoptosis; PTHrP; Runx2; tubular epithelial cells
Parathyroid hormone-related protein regulates integrin α6 and β4 levels via transcriptional and post-translational pathways
Keywords: PTHrP; Integrin α6β4; Caspase; Apoptosis; Migration
The calcium-sensing receptor in the breast
Keywords: breast; mammary gland; PMCA2; PTHrP; skeletal metastasis; lactation; milk
The promotion of osteochondral repair by combined intra-articular injection of parathyroid hormone-related protein and implantation of a bi-layer collagen-silk scaffold
Keywords: Cartilage tissue engineering; PTHrP; Collagen-silk scaffold; Osteochondral defects; Chondrocyte terminal differentiation; Chondrogenesis
Vitamin D for Health: A Global Perspective
Keywords: CD; Crohn disease; DBP; vitamin D binding protein; DC; dendritic cell; ESCEO; European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis; GWAS; genome-wide association study; HR; hazard ratio; ILT; immunoglobulin-like transcript
T cells stimulate catabolic gene expression by the stromal cells from giant cell tumor of bone
Keywords: Giant cell tumor; CD40; CD40L; PTHrP; MMP-13; RANKL;
PTHrP isoforms have differing effect on chondrogenic differentiation and hypertrophy of mesenchymal stem cells
Keywords: PTHrP; Chondrogenic differentiation; Hypertrophy; Mesenchymal stem cell
AU-rich elements in the 3â²-UTR regulate the stability of the 141 amino acid isoform of parathyroid hormone-related protein mRNA
Keywords: ARE; AU-rich element; PTHrP; parathyroid hormone-related protein; 3â²-UTR; 3â²-untranslated region; TGF-β; transforming growth factor-beta; HHM; humoral hypercalcemia of malignancy; TTP; tristetraproline; EMSA; electrophoretic mobility shift assay; Par
Expression of BMP-2 and Ets1 in BMP-2-stimulated mouse pre-osteoblast differentiation is regulated by microRNA-370
Keywords: ALP; alkaline phosphatase; BMP-2; bone morphogenetic protein-2; Ets1; V-ets Erythroblastosis Virus E26 Oncogene Homolog 1; miR; microRNA; OPN; osteopontin; Runx2; runt-related transcription factor 2; PTHrP; parathyroid hormone-related protein; Non-coding
Original Full Length ArticleSost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
Keywords: DMP1; dentin matrix protein 1; PTHrP; PTH related protein; BMP; bone morphogenetic protein; Cx43; connexin 43; WT; wild type; TG; transgenic mice; ChoB; ribosomal protein S2; LRP; low density lipoprotein receptor-related protein; Tph1; Tryptophan hydroxyl
Mechanistic investigations on the etiology of Risperdal® Consta®-induced bone changes in female Wistar Hannover rats
Keywords: ACTH; adrenocorticotropic hormone; ANOVA; analysis of variance; BMC; bone mineral content; BMD; bone mineral density; BUN; blood urea nitrogen; CT-scan; computed tomography scan; DXA; dual-energy X-ray absorptiometry; ELISA; enzyme-linked immunosorbent as
Hipercalcemia
Keywords: Hipercalcemia; Hiperparatiroidismo; PTH; PTHrp; TGF-β; RANK-LHypercalcemia; Hyperparathyroidism; PTH; PTHrp; TGF-β; RANK-L
cAMP: Novel concepts in compartmentalised signalling
Keywords: cAMP; cyclic adenosine 3â²,5â²-monophosphate; GPCR; G protein-coupled receptor; EC coupling; excitation-contraction coupling; FRET; Förster/fluorescence resonance energy transfer; CFP; cyan fluorescent protein; YFP; yellow fluorescent protein; AKAR;
Differential expression of PTHrP and its receptor in pituitary gland and gills in estradiol-treated gilthead sea bream (Sparus auratus, L.)
Keywords: Estradiol; PTHrP; PTH1R; Pituitary gland; Gill; Sea bream
Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
Keywords: PTH; parathyroid hormone; DMP1-caPTHR1; dentin matrix protein 1-constitutively active PTH receptor 1 mice; FGF23; fibroblast growth factor 23; PTHrP; PTH related protein; FGFR1; FGF receptor 1; GALNT3; galactosaminyl transferase 3; BMP; bone morphogenetic
Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis
Keywords: Bone metastasis; Osteoblast; Osteoclast; MMPs; Vicious cycle; Prostate cancer; Breast cancer; Tumor–host microenvironment; PTHrP; RANKL; TGFβ; VEGF
Advances in the biology of bone metastasis: How the skeleton affects tumor behavior
Keywords: Tumor-induced bone disease; Osteoclast activation; Breast cancer; PTHrP; Bone destruction
Metastasis and bone loss: Advancing treatment and prevention
Keywords: Metastasis; Bisphosphonate; RANK; Bone targeted; PTHrP; Bone loss; Denosumab; Zoledronic acid
Alterations of the Wnt/β-catenin pathway and its target genes for the N- and C-terminal domains of parathyroid hormone-related protein in bone from diabetic mice
Keywords: Type 1 diabetes mellitus; Bone formation; PTHrP; Wnt/β-catenin pathway
cAMP-response-element-binding protein positively regulates breast cancer metastasis and subsequent bone destruction
Keywords: CREB; Breast cancer; Bone metastasis; TGF-β; PTHrP;
Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation
Keywords: Osteostatin; Osteoblastic growth and differentiation; PTHrP; Silica-based bioceramics
Stroma in breast development and disease
Keywords: E; embryonic day; ECM; extracellular matrix; FGF; fibroblast growth factor; PTHrP; parathyroid hormone related peptide; TEB; terminal end bud; ER; estrogen receptor; EGFR; epidermal growth factor receptor; GH; growth hormone; IGF; insulin-like growth fact
Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone
Keywords: RUNX2; Runt-related transcription factor 2; OSX; OSTERIX; SOX4; Sex determining region Y-box 4; POSTN; Periostin; TWIST1; Twist homolog 1; COL1A1; Collagen 1a1; PTH; Parathyroid hormone; PTHR1; Parathyroid hormone receptor 1; PTHrP; Parathyroid hormone r
PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1
Keywords: PTHrP; Integrin α6β4; Phosphatidylinositol 3-kinase; Tiam1; Rac1
Distinct roles for mitogen-activated protein kinase phosphatase-1 (MKP-1) and ERK-MAPK in PTH1R signaling during osteoblast proliferation and differentiation
Keywords: PTH; parathyroid hormone; PTHrP; PTH-related protein; PTH1R; PTH/PTHrP receptor; MC-4; MC3T3-E1 clone-4; BMSC; Bone marrow stromal cell; MAPK; mitogen-activated protein kinase; MKP-1; MAPK phosphatase-1; ERK; extracellular signal-regulated kinase; MTT; 3-
Paraneoplastic Syndromes: An Approach to Diagnosis and Treatment
Keywords: ADH; antidiuretic hormone; CSF; cerebrospinal fluid; CT; computed tomography; IL; interleukin; IV; intravenous; IVIG; IV immunoglobulin; LEMS; Lambert-Eaton myasthenia syndrome; NICTH; non-islet cell tumor hypoglycemia; PNS; paraneoplastic neurologic sy
The TIP39-PTH2 receptor system: Unique peptidergic cell groups in the brainstem and their interactions with central regulatory mechanisms
Keywords: ACTH; adrenocorticotropin; AVP; arginine-vasopressin; CGRP; calcitonin gene-related peptide; CRH; corticotropin releasing hormone; DRG; dorsal root ganglion; ED; embryonic day; GH; growth hormone; i.c.v.; intracerebroventricular; LH; luteinizing hormone;
Effects of Calcitonin, Calcitonin Gene-Related Peptide, Human Recombinant Bone Morphogenetic Protein-2, and Parathyroid Hormone-Related Protein on Endodontically Treated Ferret Canines
Keywords: BMP; CGRP; CT; PTHrP; reparative dentin;
Phytoestrogen modulation of bone-related cytokines and its impact on cell viability in human prostate cancer cells
Keywords: Phytoestrogens; Prostate cancer; PTHrP; Osteomimetic; Apoptosis
PTH and PTHrP signaling in osteoblasts
Keywords: PTH; PTHrP; PTH1R; Osteoblast; Signaling
Parathyroid hormone 2 receptor and its endogenous ligand tuberoinfundibular peptide of 39 residues are concentrated in endocrine, viscerosensory and auditory brain regions in macaque and human
Keywords: tuberoinfundibular peptide; neuroendocrine modulator; primate hypothalamus; subparafascicular area; medial paralemniscal nucleus; in situ hybridization in monkey brain; CRH; corticotropin-releasing hormone; Cy; carbocyanine; DAPI; 4â²,6-diamidino-2-pheny
Commonalities in the endocrinology of stem cell biology and organ regeneration
Keywords: PTH; parathyroid hormone; HSC; haematopoietic stem cell; IGF; insulin-like growth factor; PTHrP; PTH-related peptide; FGF; fibroblast growth factor; ESC; embryonic stem cell; GLP; glucagon-like peptide; T3; triiodothyronine; TR; thyroid hormone receptor;
PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs
Keywords: Chondrogenesis; PTHrP; Tissue engineering; Hypertrophy; Differentiation
PTHrP promotes homotypic aggregation of breast cancer cells in three-dimensional cultures
Keywords: PTHrP; Integrin α6; KISS-1; 3D culture; TGFβ
Disp1 regulates growth of mammalian long bones through the control of Ihh distribution
Keywords: Disp1; Dispatched1; Ihh; Indian hedgehog; N-Shh; non-cholesterol modified Sonic hedgehog; PTHrP; parathyroid hormone related peptide; Shh; sonic hedgehog; Ptch1; Patched1; Smo; Smoothened; PPR; Parathyroid hormone-PTHrP receptor; Disp2; Dispatched2; Disp1
PTHrP promotes malignancy of human oral cancer cell downstream of the EGFR signaling
Keywords: PTHrP; EGFR; AG1478; RNA interference; Oral cancer; Therapeutics
Melatonin synthesis under calcium constraint in gilthead sea bream (Sparus auratus L.)
Keywords: Melatonin; Hypocalcemia; PTHrP; Calcitriol; Sea bream; Diet;
Trps1 deficiency enlarges the proliferative zone of growth plate cartilage by upregulation of Pthrp
Keywords: Trps1; Growth plate; Pthrp; Chondrocytes; Differentiation;