دانلود مقالات ISI درباره Ptp1B + ترجمه فارسی

Design, synthesis, and evaluation of 2-substituted ethenesulfonic acid ester derivatives as protein tyrosine phosphatase 1B inhibitors

Keywords: PTP1B; TCPTP; Diabetes; Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The Zinc Transporter Zip14 Influences c-Met Phosphorylation and Hepatocyte Proliferation During Liver Regeneration in Mice

Keywords: Micronutrient; Signal Transduction; Tissue Regeneration; Interleukin-6; ANOVA; analysis of variance; BrdU; bromodeoxyuridine, CM, conditioned medium; ERK; extracellular signal-regulated kinase; HGF; hepatocyte growth factor; IL; interleukin; LPS; lipopo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control

Keywords: PTP1B; Type 2 diabetes mellitus; Obesity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Chronic central leptin infusion differently modulates brain and liver insulin signaling

Keywords: PTP1B; Leptin; Insulin-resistance; Insulin sensitivity; Signaling pathways; Hypothalamus; Liver

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Calcium as a mediator between erythropoietin and protein tyrosine phosphatase 1B

Keywords: Erythropoietin; PTP1B; Calcium; Calpain; TRPC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia

Keywords: PTPIP51; c-Kit; SFK; PTP1B; Acute myeloid leukemia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1

Keywords: AMPK; AMP-activated protein kinase; HEK293; human embryo kidney 293 cells; IIS; insulin/insulin-like signaling; IRS; insulin receptor substrate; MAPK; mitogen activated protein kinase; PGC-1α; PPARγ general co-activator 1α; PI3K; phosphoinositide 3-kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling

Keywords: ROS; reactive oxygen species; Nox; NADPH oxidase; O2•−; superoxide; RNS; reactive nitrogen species; •NO; nitric oxide; SOD; superoxide dismutase; NOS; nitric oxide synthase; GSH; glutathione; AngII; angiotensin II; PDGF; platelet-derived growth fact

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors

Keywords: Petroselinic acid; PTP1B; N-(Alkoxyphenyl)-aminocarbonylbenzoic acid derivatives; Synthesis; Diabetes

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Studies on two types of PTP1B inhibitors for the treatment of type 2 diabetes: Hologram QSAR for OBA and BBB analogues

Keywords: HQSAR; PTP1B; Inhibitors; OBA; BBB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and peptide incorporation of an unnatural amino acid containing activity-based probe for protein tyrosine phosphatases

Keywords: Protein tyrosine phosphatase; Activity-based probe; Unnatural amino acid; Quinone methide; Affinity labeling; PTP1B; PTP4A3

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents

Keywords: 3,5-Diarylisoxazole; Anti-hyperglycemic activity; Lipid lowering activity; PTP1B

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes

Keywords: Astragalus polysaccharide; PTP1B; ATF6; ER stress; Type 2 diabetes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism

Keywords: Astragalus membranaceus; Polysaccharides; Obesity; Insulin resistance; PTP1B; Endoplasmic reticulum; Stress

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors

Keywords: Protein tyrosine phosphatases; PTP1B; LMW-PTP; 5-Arylidene-2-phenylimino-4-thiazolidinones; Inhibitors

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of the insulin antagonistic protein tyrosine phosphatase 1B by dietary Se studied in growing rats

Keywords: Selenium; Selenite; Selenate; PTP1B; Glutathionylation; Diabetes; Insulin resistance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Designing better coumarin-based fluorogenic substrates for PTP1B

Keywords: PTP1B; Coumarin; Substrate; Fluorogenic

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines

Keywords: PTP1B; Isothiazolidinone; Phosphotyrosine; Protein tyrosine phosphatase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold

Keywords: PTP1B; Phosphatase; Bioisostere; Sulfonamide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Derivatives of 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene as PTP1B inhibitors with hypoglycemic activity

Keywords: PTP1B; Diabetes; Inhibitor; Salicylic acid

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition

Keywords: PTP1B; Non-peptidyl inhibitors; Phosphotyrosine mimics

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of small interference RNA against PTP1B and TCPTP on insulin signaling pathway in mouse liver: Evidence for non-synergetic cooperation

Keywords: PTP1B; TCPTP; siRNA; Fatty acid synthase promoter; Diabetic mouse model;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Methylenedisalicylic acid derivatives: New PTP1B inhibitors that confer resistance to diet-induced obesity

Keywords: Methylenedisalicylic acid; PTP1B; Obesity; Protein tyrosine phosphatase; Inhibitor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: A new class of protein tyrosine phosphatase 1B inhibitors

Keywords: Protein tyrosine phosphatase 1B; PTP1B; Inhibitor; Diabetes; Obesity; Structure-based design; Insulin resistance; Indole; Thiazole; Phospho-tyrosine; Insulin sensitivity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

A molecular dynamics study of WPD-loop flexibility in PTP1B

Keywords: Molecular dynamics; WPD-loop; S-loop; Allosteric inhibition; PTP1B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Modulation of Spc1 stress-activated protein kinase activity by methylglyoxal through inhibition of protein phosphatase in the fission yeast Schizosaccharomyces pombe

Keywords: Methylglyoxal; MAP kinase; Protein phosphatase; Schizosaccharomyces pombe; PTP1B; Signal transduction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

CoMFA based de novo design of pyridazine analogs as PTP1B inhibitors

Keywords: Insulin and leptin signaling; Type 2 diabetes; Obesity; PTP1B; CoMFA; LeapFrog

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations

Keywords: Protein tyrosine phosphatases (PTPs); Allele-specific inhibitors; Inhibitor sensitization; Protein engineering; PTP1B; T-cell PTP (TCPTP); PTPH1; Hematopoietic PTP (HePTP)

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Direct interaction between ER membrane-bound PTP1B and its plasma membrane-anchored targets

Keywords: Bimolecular Fluorescence Complementation; Insulin receptor; PKC; PTP1B; Src

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6

Keywords: HEK293; human embryonic kidney 293; PTP1B; tyrosine phosphatase 1B; DMHV; bis-(N,N-dimethyl-hydroxamido) hydroxo-vanadate; SOC; store operated Ca2+ channel; BiFC; bimolecular fluorescence complementation; PV; pervanadate; ROS; reactive oxygen species; GST

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

A gatekeeper residue for inhibitor sensitization of protein tyrosine phosphatases

Keywords: Protein engineering; Inhibitor sensitization; Protein tyrosine phosphatases; PTP1B

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

A targeted molecular dynamics study of WPD loop movement in PTP1B

Keywords: Targeted molecular dynamics; WPD loop; Allosteric inhibition; PTP1B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake

Keywords: PTP1B; Inhibitor; Ursolic acid; Traditional Chinese medicinal herb; Derivative; Competitive; Insulin receptor; Glucose uptake

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Enzyme occupancy measurement of intracellular protein tyrosine phosphatase 1B using photoaffinity probes

Keywords: Photoaffinity; PTP1B; Diazirine; Occupancy; HepG2

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Sulfiredoxin: a potential therapeutic agent?

Keywords: Glutathione; Glutathionylation; Sulfiredoxin; Reactive oxygen/nitrogen species; Oxidative stress; GST; ALS; amylotrophic lateral sclerosis; ER; endoplasmic reticulum; FRDA; Friedrich's ataxia; Grx; glutaredoxin; GSH; glutathione; GSSG; glutathione disul

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors

Keywords: Tripeptides; Bioterrorism; pTyr mimetics; YopH; PTP1B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Reduction of PTP1B by RNAi upregulates the activity of insulin controlled fatty acid synthase promoter

Keywords: PTP1B; RNAi; Fatty acid synthase; Hepatocytes; Hydrodynamic injection;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases

Keywords: PTP1B; DIFMUP; Phosphatase inhibitor; Fluorescence; Insulin signaling;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

The genus Ardisia: a novel source of health-promoting compounds and phytopharmaceuticals

Keywords: 1-NP; 1-nitropyrene; BIR3; baculovirus IAP repeat third domain; cAMP; cyclic adenosine monophosphate; DPPH; 1,1-diphenyl-2-picrylhydrazyl; EGCG; (−)-epigallocatechin gallate; HIV; human immunodeficiency virus; MS/MS; mass spectrometry/mass spectrometer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Functional studies of protein tyrosine phosphatases with chemical approaches

Keywords: PTP; protein tyrosine phosphatase; PTK; protein tyrosine kinase; FAK; focal adhesion kinase; ERK; extracellular signal-regulated kinase; p130Cas; Crk associated substrate.; Protein tyrosine phosphatase; PTP1B; Protein tyrosine phosphatase inhibitor; Chemi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: From diabetes, obesity to cell cycle, and cancer

Keywords: EGFR; epidermal growth factor receptor; GHR; growth hormone receptor; IGF-IR; insulin-like growth factor I receptor; IR; insulin receptor; IRS; insulin receptor substrate; JAK; janus kinase; KO; knockout; LeptinR; leptin receptor; PDGFR; platelet derived

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Tyrosine phosphatase PTP1B interacts with TRPV6 in vivo and plays a role in TRPV6-mediated calcium influx in HEK293 cells

Keywords: 2-APB; 2-aminoethyldiphenyl borate; BiFC; bimolecular fluorescence complementation; [Ca2+]cyt; cytoplasmic [Ca2+]; CRAC; Ca2+release-activated Ca2+ entry; DMHV; bis-(N,N-dimethyl-hydroxamido) hydroxo-vanadate; ICRAC; Ca2+ release-activated Ca2+ current; I

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Substrate-trapping techniques in the identification of cellular PTP targets

Keywords: Substrate-trapping; PTP; Protein-tyrosine phosphatase; PTP1B; GST pulldown;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of the catalytic activity of PTP1B: Roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310

Keywords: Tyrosine phosphatase; PTP1B; Cell adhesion; Integrin;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه