Keywords: ژن فعال سازی مجدد ترکیب; Gene therapy; Omenn syndrome; autoimmunity; lentiviral vector; Rag genes; AIRE; Autoimmune regulator; BAFF; B cell-activating factor; BM; Bone marrow; GT; Gene therapy; HSCT; Hematopoietic stem cell transplantation; Linâ; Lineage negative; LV; Lentivi
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Keywords: ژن فعال سازی مجدد ترکیب; Primary immunodeficiency; malignancy; tumor predisposition; immune surveillance; pre-existing condition; ALL; Acute lymphoblastic leukemia; ALPS; Autoimmune lymphoproliferative syndrome; AT; Ataxia teleangiectasia; CHH; Cartilage-hair hypoplasia; CID; Com
Keywords: ژن فعال سازی مجدد ترکیب; Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: ژن فعال سازی مجدد ترکیب; Severe combined immunodeficiency; radiation sensitivity; hematopoietic cell transplantation; nonhomologous end joining; DNA repair; ART-SCID; Artemis-deficient severe combined immunodeficiency; ATG; Antithymocyte globulin; DNA-PKcs; DNA-dependent protein
Keywords: ژن فعال سازی مجدد ترکیب; Immunology; primary immunodeficiency; dedicator of cytokinesis 8; HIV1; recombination-activating gene 1; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; ADA; Adenosine deaminase; ApoE; Apo
Keywords: ژن فعال سازی مجدد ترکیب; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; BWA; Burrows Wheeler Alignment tool; CGH; comparative genomic hybridization; CNV; copy number variations; DGV; database of genomic variants; EGA; European Genome-phenome Archive; FISH; fluore
Keywords: ژن فعال سازی مجدد ترکیب; Severe combined immunodeficiency; hematopoietic cell transplantation; sibling donors; unrelated donors; umbilical cord blood; conditioning; serotherapy; ADA; Adenosine deaminase; aGVHD; Acute graft-versus-host disease; BM; Bone marrow; cGVHD; Chronic graf
Staged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection
Keywords: ژن فعال سازی مجدد ترکیب; Resident memory T cells; TRM; Candida albicans; IL-17; TH17; CD4+ TRM; AC; Arrest coefficients; CD62L; CD62 ligand; DC; Dendritic cell; GFP; Green fluorescent protein; HK; Heat-killed; KLRG-1; Killer cell lectin-like receptor subfamily G member 1; MV; Mea
The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D
Keywords: ژن فعال سازی مجدد ترکیب; Allergy; asthma; Staphylococcus aureus; sensitization; serine protease; AECII; Airway epithelial cell type II; APC; Allophycocyanin; BALF; Bronchoalveolar lavage fluid; DC; Dendritic cells; DMEM; Dulbecco modified Eagle medium; FACS; Fluorescence-activate
Tripartite motif-containing (TRIM) 21 negatively regulates intestinal mucosal inflammation through inhibiting TH1/TH17Â cell differentiation in patients with inflammatory bowel diseases
Keywords: ژن فعال سازی مجدد ترکیب; Tripartite motif-containing 21; inflammatory bowel disease; CD4+ T cells; mucosal inflammation; TH1; TH17; A-CD; Active Crohn disease; A-UC; Active ulcerative colitis; CD; Crohn disease; CDAI; Crohn's Disease Activity Index; HC; Healthy control subject; I
TH17Â cells mediate inflammation in a novel model of spontaneous experimental autoimmune lacrimal keratoconjunctivitis with neural damage
Keywords: ژن فعال سازی مجدد ترکیب; Autoimmune lacrimal keratoconjunctivitis; TH17Â cell; APC; Antigen-presenting cell; DC; Dendritic cell; DED; Dry eye disease; EALK; Experimental autoimmune lacrimal keratoconjunctivitis; Foxp3; Forkhead box protein 3; IBD; Inflammatory bowel disease; iNOS
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Keywords: ژن فعال سازی مجدد ترکیب; Lung inflammation; lung adenocarcinoma; fibroblastic reticular cells; tumor microenvironment; ADC; Adenocarcinoma; APC; Allophycocyanin; CAF; Cancer-associated fibroblast; DC; Dendritic cell; DT; Diphtheria toxin; ECM; Extracellular matrix; EpCAM; Epithel
Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders
Keywords: ژن فعال سازی مجدد ترکیب; Ataxia-telangiectasia; Cernunnos-XLF deficiency; DNA repair disorders; DNA ligase IV deficiency; hematopoietic stem cell transplantation; Nijmegen breakage syndrome; aGvHD; Acute graft-versus-host disease; AT; Ataxia-telangiectasia; ATG; Anti-thymocyte gl
Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice
Keywords: ژن فعال سازی مجدد ترکیب; Allergic mechanisms; innate lymphoid cells; mouse models; CLP; Common lymphoid progenitor; DAPI; 4â²,6-Diamidino-2-phenylindole; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; ILC2; Type 2 innate lymphoid cell; IL-7Rα; IL-7 receptor α; iNKT;
Exome and genome sequencing for inborn errors of immunity
Keywords: ژن فعال سازی مجدد ترکیب; Next-generation sequencing; whole-exome sequencing; whole-genome sequencing; targeted sequencing; primary immunodeficiency; AD; Autosomal dominant; AF; Allele frequency; AR; Autosomal recessive; CADD; Combined annotation-dependent depletion; CID; Combined
XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency
Keywords: ژن فعال سازی مجدد ترکیب; DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro
Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency
Keywords: ژن فعال سازی مجدد ترکیب; V(D)J recombination; nonhomologous end-joining; DNA repair; ARTEMIS deficiency; DCLRE1C mutations; severe combined immunodeficiency; A-MuLV; Abelson murine leukemia virus; ExAC; Exome Aggregation Consortium; GFP; Green fluorescent protein; IR; Ionizing ra
Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells
Keywords: ژن فعال سازی مجدد ترکیب; Chronic Infection; Hepatitis; Tolerance; ALT; alanine aminotransferase; APC; allophycocyanin; Arm; Armstrong strain; BTLA; B and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T lymphocyte; ELISA; enzyme-lin
Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
Keywords: ژن فعال سازی مجدد ترکیب; Type 2 innate lymphoid cells; IL-33; T cells; feedback circuit; chronic asthma; BAL; Bronchoalveolar lavage; γc; Common γc chain of the IL-2 receptor; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 lymphocytes; DRA; Dust mite, ragw
CD11a polymorphisms regulate TH2 cell homing and TH2-related disease
Keywords: ژن فعال سازی مجدد ترکیب; Asthma; allergic disease; CD11a; TH2 cell; homing; polymorphism; allele; congenic; biomarker; AHR; Airway hyperreactivity; CAMP; Childhood Asthma Management Program; LD; Linkage disequilibrium; LFA-1; Leukocyte function-associated antigen 1; MIBD; Metal
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency
Keywords: ژن فعال سازی مجدد ترکیب; Recombination-activating gene 1; V(D)J recombination; severe combined immune deficiency; Omenn syndrome; autoimmunity; genotype-phenotype correlation; immune repertoire; A-MuLV; Abelson murine leukemia virus; CDR; Complementarity-determining region; CID-G
B-cell reconstitution for SCID: Should a conditioning regimen be used in SCID treatment?
Keywords: ژن فعال سازی مجدد ترکیب; Severe combined immunodeficiency; conditioning regimen; hematopoietic stem cell transplantation; B-cell function; immunoglobulin therapy; CR; Conditioning regimen; GvHD; Graft-versus-host disease; HSCT; Hematopoietic stem cell transplantation; IL-7Rα; IL
Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: Results of the first 2 years
Keywords: ژن فعال سازی مجدد ترکیب; Severe combined immunodeficiency; newborn screening; T-cell receptor excision circle; T-cell lymphopenia; DiGeorge syndrome; CHARGE; Coloboma (ocular), heart anomaly, atresia (choanal), retardation, genital and ear anomalies; CHH; Cartilage-hair hypoplasi
Rearrangement patterns of the canine TCRγ locus in a distinct group of T cell lymphomas
Keywords: ژن فعال سازی مجدد ترکیب; D; diversity; EMBL; European Molecular Biology Laboratory; J; joining; PCR; polymerase chain reaction; RAG; recombination-activating gene; RSS; recombination signal sequence; TCR; T cell receptor; TRG; T cell receptor gamma; V; variable; Dog; Gamma delta
Defect of regulatory T cells in patients with Omenn syndrome
Keywords: ژن فعال سازی مجدد ترکیب; Immunodeficiency; V(D)J recombination; Omenn syndrome; regulatory T cells; FOXP3; anergy and tolerance; thymus and the development of T lymphocytes; AIRE; Autoimmune regulator; FOXP3; Forkhead box protein P3; HD; Healthy donor; OS; Omenn syndrome; RAG; Re