Keywords: اپی ادیس انسانی بازسازی شده; Bis-quaternary ammonium compounds; Inflammatory cytokines; Antiseptics; Cytotoxicity assay; Reconstructed human epidermis; Keratinocytes; BAC; benzalkonium chloride; bis-QACs; bis-quaternary ammonium compounds; CCK-8; Cell Counting Kit-8; CHG; chlorhexidi
مقالات ISI اپی ادیس انسانی بازسازی شده (ترجمه نشده)
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Keywords: اپی ادیس انسانی بازسازی شده; DEHP; Diethylhexyl phthalate; DINP; Diisononyl phthalate; DPBS; Dulbecco's phosphate-buffered saline; ECVAM; European Center for Validation of Alternative Methods; EC50; Effective concentration 50%; ESBO; Epoxidized soybean oil; HA; Heptanoic acid; IVLSL;
Keywords: اپی ادیس انسانی بازسازی شده; AD; atopic dermatitis; RHE; reconstructed human epidermis; epoB; epothilone B; H&E; hematoxylin/eosin; TEWL; transepidermal water loss; Stabilization of microtubules; Keratinocyte differentiation; Lamellar bodies; Intercellular junctions; Barrier recovery
Keywords: اپی ادیس انسانی بازسازی شده; Medical devices; Irritation; Alternative testing; In vitro; Reconstructed human epidermis;
Keywords: اپی ادیس انسانی بازسازی شده; Reconstructed human epidermis; Full thickness skin; Risk assessment; Skin corrosion;
Keywords: اپی ادیس انسانی بازسازی شده; 4-ABP; 4-aminobiphenyl; ARNT; AHR nuclear translocator; AHR; aryl hydrocarbon receptor; BaP; benzo[a]pyrene; BPDE; BaP diol epoxide; CAP; concentrated ambient particles; COX-1,-2; cyclooxygenase-1,-2; EGFR; epidermal growth factor receptor; FICZ; 6-formyl
Keywords: اپی ادیس انسانی بازسازی شده; Skin irritation model; reconstructed human epidermis; keratinocytes; human skin; 3D; Three Dimensional; BSA; Bovine Serum Albumin; ECVAM; European Centre for the Validation of Alternative Methods; ET50; Exposure Time 50; GHS; Globally Harmonized System; H
Keywords: اپی ادیس انسانی بازسازی شده; Drug delivery systems; Reconstructed human epidermis; Senescence-associated secretory phenotype; Skin absorption; Skin aging; Tissue engineering;
Keywords: اپی ادیس انسانی بازسازی شده; AD; atopic dermatitis; NMF; natural moisturizing factor; PAD; peptidylarginine deiminase; PCA; pyrrolidone-5-carboxylic acid; RH; relative humidity; RHE; reconstructed human epidermis; TEWL; transepidermal water loss; UCA; urocanic acid; Atopic dermatitis
Keywords: اپی ادیس انسانی بازسازی شده; Reconstructed human epidermis; Hair follicle; Cutaneous metabolism; Gene expression; Functional activity; ADH; alcohol dehydrogenases; ALDH; aldehyde dehydrogenases; AhR; aryl hydrocarbon receptor; PI-APCI; APCI source in the positive mode; B(a)P; benzo(a
Keywords: اپی ادیس انسانی بازسازی شده; ATCC; American Type Culture Collection; COLIPA; Now Cosmetics Europe - The Personal Care Association; ECVAM; European Centre for the Validation of Alternative Methods; EFSA; European Food Safety Authority; ESAC; ECVAM Scientific Advisory Committee; GHS;
Keywords: اپی ادیس انسانی بازسازی شده; Atopic dermatitis; Reconstructed human epidermis; Cholesterol; Interleukins; Epidermal barrier;
Keywords: اپی ادیس انسانی بازسازی شده; EURL-ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; FHG; Fraunhofer Gesellschaft; FUB; Institute of Pharmacy at the Freie Universität Berlin; UN GHS; United Nations Globally Harmonized System of Classification and Labellin
Keywords: اپی ادیس انسانی بازسازی شده; hDF; human dermal fibroblasts; hEK; human epidermal keratinocytes; RhE; reconstructed human epidermis; RhS; reconstructed human skin; S. mansoni; Schistosoma mansoni; S. ratti; Strongyloides ratti; Tissue engineering; Human skin equivalents; Strongyloid
SkinEthic⢠RHE for in vitro evaluation of skin irritation of medical device extracts
Keywords: اپی ادیس انسانی بازسازی شده; Medical devices; Reconstructed human epidermis; RHE; Skin irritation; In vitro; Biocompatibility; ISO 10993; Alternative to animal testing;
Assessment of metal sensitizer potency with the reconstructed human epidermis IL-18 assay
Keywords: اپی ادیس انسانی بازسازی شده; EC50; chemical concentration resulting in 50% decrease in cell viability; IL-18; Interleukin 18; SI2; 2 fold stimulation index; RhE; reconstructed human epidermis; VUmc; VU university medical center; Immunotoxicity; in vitro test; Cytokine; Medical device
Reconstructed human epidermis for in vitro studies on atopic dermatitis: A review
Keywords: اپی ادیس انسانی بازسازی شده; Reconstructed human epidermis; Atopic dermatitis; Filaggrin; Lipid; Inflammation; Pruritus;
Evaluation of the medical devices benchmark materials in the controlled human patch testing and in the RhE in vitro skin irritation protocol
Keywords: اپی ادیس انسانی بازسازی شده; 4â¯h HPT; 4-hour human patch test; 18â¯h HPT; 18-hour human patch test; ET-50; Exposure time that induce 50% cell viability; DPBS; Dulbecco's phosphate buffered saline; GP; Genapol®; HA; heptanoic acid; I; irritant; ISO; International Organization for
Topical treatments with acylceramide dispersions restored stratum corneum lipid lamellar structures in a reconstructed human epidermis model
Keywords: اپی ادیس انسانی بازسازی شده; LPP; long periodicity phase; SPP; short-periodicity phase; SC; stratum corneum; SAXS; small-angle X-ray scattering; TEM; transmission electron microscopy; RHE; reconstructed human epidermis; SDS; sodium dodecyl sulfate; TEWL; transepidermal water loss; EO
Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDermâ¢
Keywords: اپی ادیس انسانی بازسازی شده; DPBS; Dulbecco's phosphate buffered saline; EPI-200-SIT-MD; EpiDerm skin irritation test for medical devices; ET50; time required to reduce viability to 50%; HA; heptanoic acid; IC 50; inhibition concentration that to reduce viability to 50%; ISO; the Int
A way forward of alternative methods in China: Implementation of skin corrosivity potential using in vitro reconstructed human epidermis
Keywords: اپی ادیس انسانی بازسازی شده; CASRN; Chemical Abstract Service Registry Number; d-PBS; Dulbecco's Phosphate Buffered Saline; EURL ECVAM; European Union Reference Laboratory for European Centre for the Validation of Alternative Methods; GHS; Globally harmonized system of classification
Regulatory accepted but out of domain: In vitro skin irritation tests for agrochemical formulations
Keywords: اپی ادیس انسانی بازسازی شده; Skin irritation; Skin corrosion; OECD TG 404; OECD TG 431; OECD TG 439; Agrochemical formulation; Reconstructed human epidermis; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; Cat; Category; CLP; Classification, Labelling,
Comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references
Keywords: اپی ادیس انسانی بازسازی شده; Ac; Acylating agents; ACD; Allergic Contact Dermatitis; AOP; Adverse Outcome Pathway; ARE; Antioxidant Response Element; DC; dendritic cell; DMSO; dimethyl sulfoxide; DNCB; dinitrochlorobenzene; DPRA; Direct Peptide Reactivity Assay; ECVAM; European Centr
Ozone-induced damage in 3D-Skin Model is prevented by topical vitamin C and vitamin E compound mixtures application
Keywords: اپی ادیس انسانی بازسازی شده; O3; ozone; MIXs; antioxidant mixtures; RHE; reconstructed human epidermis; OS; oxidative stress; ROS; reactive oxygen species; HNE; 4-hydroxy2-nonenal; HNE-PA; 4-hydroxy2-nonenal protein adducts; ELISA; enzyme-linked immunosorbent assay; NF-κB; nuclear f
Evaluation of fibrin-based dermal-epidermal organotypic cultures for in vitro skin corrosion and irritation testing of chemicals according to OECD TG 431 and 439
Keywords: اپی ادیس انسانی بازسازی شده; RhE; reconstructed human epidermis; ORG; organotypic skin culture; H&E; hematoxylin and eosin; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; BD CBA; Becton Dickinson Cytometric Bead Array; OD; optical density; RH; relative humidity; R
RNAi mediated IL-6 in vitro knockdown in psoriasis skin model with topical siRNA delivery system based on liquid crystalline phase
Keywords: اپی ادیس انسانی بازسازی شده; Liquid crystalline nanodispersion; Small interfering RNA; In vitro knockdown; Reconstructed human epidermis; Topical delivery system; Skin penetration
Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin⢠using HPLC/UPLC-spectrophotometry in the MTT-reduction assay
Keywords: اپی ادیس انسانی بازسازی شده; CAS RN; Chemical Abstract Service Registry Number; R2; coefficient of determination; Cat. 1; Category 1; Cat. 2; Category 2; EIT; eye irritation test; DG SANCO; European Commission Directorate General for Health and Consumer Protection; EURL ECVAM; Europe
Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis
Keywords: اپی ادیس انسانی بازسازی شده; Cer; ceramide; Ctrl; control; GTP; guanosine triphosphate; GTPase; GTP hydrolase; LB; lamellar body; LRO; lysosome-related organelle; RHE; reconstructed human epidermis; shRNA; short hairpin RNA; TEWL; transepidermal water loss; TGN; trans-Golgi network;
Predictability of in vitro dermal assays when evaluating fatty amine derivatives
Keywords: اپی ادیس انسانی بازسازی شده; ECVAM; European Centre for the Validation of Alternative Methods; GHS; UN Globally Harmonized System of Classification and Labelling of Chemicals; MTT; vital dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (Thiazolyl blue tetrazolium brom
Phospholipid Vesicle-Based Permeation Assay and EpiSkin® in Assessment of Drug Therapies Destined for Skin Administration
Keywords: اپی ادیس انسانی بازسازی شده; permeability; reconstructed human epidermis; PVPA; EpiSkin®; skin; liposomes; lipids; in vitro; transdermal drug delivery;
Evaluation of in vitro vs. in vivo methods for assessment of dermal absorption of organic flame retardants: A review
Keywords: اپی ادیس انسانی بازسازی شده; BFRs; brominated flame retardants; BPA; bisphenol A; BTBPE; 1,2-bis(2,4,6-tribromophenoxy)ethane; DBDPE; decabromodiphenylethane; EU; European Union; EVCAM; European Centre for Validation of Alternative Methods; FRs; flame retardants; FT; full-thickness s
An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic⢠Reconstructed Human Epidermis
Keywords: اپی ادیس انسانی بازسازی شده; ECVAM; European Center for the Validation of Alternative Methods; ESAC; ECVAM Scientific Advisory Committee; EU; European Union; EU CLP; European Union System of Classification of Chemicals implemented in the EU Classification, Labelling and Packaging Reg
Keratinization induced by air exposure in the reconstructed human epidermal model: An in vitro model of a cultured epithelial autograft
Keywords: اپی ادیس انسانی بازسازی شده; Cultured epithelial autograft; Reconstructed human epidermis; Keratinocytes; Stratum corneum; Keratinization
Performance of the N/TERT epidermal model for skin sensitizer identification via Nrf2-Keap1-ARE pathway activation
Keywords: اپی ادیس انسانی بازسازی شده; N/TERT; Reconstructed human epidermis; Skin sensitization; Keap1; Nrf2; DNCB;
Sub-categorisation of skin corrosive chemicals by the EpiSkin⢠reconstructed human epidermis skin corrosion test method according to UN GHS: Revision of OECD Test Guideline 431
Keywords: اپی ادیس انسانی بازسازی شده; BLR; Between-laboratory reproducibility; ECHA; European Chemicals Agency; ESAC; ECVAM Scientific Advisory Committee; EU; European Union; EU CLP; European Union System of Classification of Chemicals implemented in the EU Classification, Labelling and Packa
Esterase activity in excised and reconstructed human skin - Biotransformation of prednicarbate and the model dye fluorescein diacetate
Keywords: اپی ادیس انسانی بازسازی شده; Ac; acetone; BM; betamethasone; DMSO; dimethyl sulfoxide; CV; coefficient of variation; FDA; fluorescein diacetate; hCE; human carboxylesterase; HaCaT; human keratinocyte cell line; IL-8; interleukin-8; LDH; lactate dehydrogenase; NHDF; normal human derma
Successful micronucleus testing with the EPI/001 3D reconstructed epidermis model: Preliminary findings
Keywords: اپی ادیس انسانی بازسازی شده; RHE, reconstructed human epidermis; MMC, mitomycin C; VB, vinblastine; MGG, May–Grünwald–Giemsa; H&E, Haematoxylin & Eosin; MN, micronucleusMicronucleus; Reconstructed human epidermis; Genotoxicity; Cytochalasin B; Mitomycin C; Vinblastine
Regulation of tight junction permeability by sodium caprate in human keratinocytes and reconstructed epidermis
Keywords: اپی ادیس انسانی بازسازی شده; Tight junction; Human keratinocyte; Reconstructed human epidermis; Occuludin; Claudin-1; Sodium caprate; Paracellular permeability
Simultaneous absorption of vitamins C and E from topical microemulsions using reconstructed human epidermis as a skin model
Keywords: اپی ادیس انسانی بازسازی شده; Microemulsion; Reconstructed human epidermis; Percutaneous absorption; Antioxidant; Vitamin C; Vitamin E
In vitro skin absorption and drug release – A comparison of six commercial prednicarbate preparations for topical use
Keywords: اپی ادیس انسانی بازسازی شده; Prednicarbate; Topical dermatics; Drug release; Skin absorption; Skin metabolism; Reconstructed human epidermis
Leiden reconstructed human epidermal model as a tool for the evaluation of the skin corrosion and irritation potential according to the ECVAM guidelines
Keywords: اپی ادیس انسانی بازسازی شده; Reconstructed human epidermis; Skin corrosion; Skin irritation; ECVAM
Reconstructed human epidermis: A model to study the barrier function
Keywords: اپی ادیس انسانی بازسازی شده; 29.30.âKv; 87.64.ât; Reconstructed human epidermis; Skin; Nuclear microscopy; Micro-PIXE;
Reconstructed epidermis versus human and animal skin in skin absorption studies
Keywords: اپی ادیس انسانی بازسازی شده; Alternative methods; Skin absorption; Skin; Reconstructed human epidermis; Skin models; Epidermis models; Regulatory toxicology; Replacement of animal experiments; BSA; bovine serum albumin; ECVAM; European Centre for the Validation of Alternative Methods
The human epidermis models EpiSkin®, SkinEthic® and EpiDerm®: An evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport
Keywords: اپی ادیس انسانی بازسازی شده; Reconstructed human epidermis; Lipid composition; Biochemical markers; Drug delivery; Skin; HPTLC; high performance thin layer chromatography; IL; Interleukin; LDH; lactate dehydrogenase; mRNA; messenger RNA; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl