Keywords: PD; Parkinson disease; AD; Alzheimer's disease; mtDNA; mitochondrial DNA; dâGal; dâgalactose; Rh123; Rhodamine 123; OCR; oxygen consumption rate; N2a; mouse neuroblastoma cell; MTT; 3â4,5âdimethylâ2âthiazolylâ2,5âdiphenylâ2âHâtetrazo
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Asiatic acid; Hepatic ischemia/reperfusion injury; Reactive oxygen species; Mitochondrial anoxia/reoxygenation; I/R; ischemia/reperfusion; AA; asiatic acid; A/R; anoxia/reoxygenation; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; Rh
Keywords: PTC; papillary thyroid carcinoma; ATC; anaplastic thyroid carcinoma; TC; thyroid cancer; TSH; thyroid stimulating hormone; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide; DMSO; dimethyl sulfoxide; Rh123; 2-(6-Amino-3-imino-3H-xanthen-9-y
Keywords: ÎΨ; mitochondrial membrane potential; cmH2DCF; chloromethyldihydrodichlorofluorescein; LTR; LysoTracker Red; PI; propidium iodide; Rh123; rhodamine 123; ROS; reactive oxygen species; TMRE; tetramethylrhodamine ethyl ester; TMRM; tetramethylrhodamine met
Keywords: Homoharringtonine; Emetine; Trypanosome; Protein biosynthesis; Cell cycle; Mitochondrial membrane potential; T. b. brucei; Trypanosoma brucei brucei; FDA; Food and Drug Administration; Rh123; rhodamine 123; CCCP; carbonyl cyanide 3-chlorophenylhydrazone;
Keywords: Rh123; Rhodamine 123; HMG-CoA reductase; 3-hydroxy-3-methyl-glutaryl-CoA reductase; ROS; reactive oxygen species; DMSO; dimethylsulphoxide; FCCP; Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; DETCA; diethylthiocarbamate; TEA; tetraethylammonium; 3
Keywords: PTP; permeability transition pore; OMM; outer mitochondrial membrane; IMM; inner mitochondrial membrane; CsA; cyclosporin A; CyPD; cyclophilin D; CyPA; cyclophilin A; F-ATP synthase; FOF1 ATP synthase; HTS; high-throughput screening; TRO40303; 3,5-seco-4-
Keywords: Targeted nanoparticles; Heterogenous cancer cells; Rh123; MDR;
Keywords: MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium; BA; bongkrekic acid; TFP; trifluoperazine; MitoMP; mitochondria membrane potential; MPTP; mitochondrial permeability transition pore; ANT; adenine nucleotide translocase; NAC; N-acetyl cysteine; R
Keywords: ATZ; atrazine; BrdU; bromodeoxyuridine; CFDA-SE; carboxyfluorescein succinimidyl ester; ConA; concanavalin A; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethyl sulfoxide; FCS; Fetal Calf Serum; 3H-TdR; 3H-thymine deoxyriboside; MACS;
Keywords: AGEs; advanced glycation end products; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; GCL; glutamate cysteine ligase; GSH; glutathione; HO-1; heme oxyge
Keywords: Supersaturated polymeric micelle; Cyclosporine A; Soluplus®; Supersaturation degree; Oral bioavailability; Cellular uptake and transport; CsA; cyclosporine A; CsD; cyclosporine D; P-gp; P-glycoprotein; PMs; polymeric micelles; HPMC-AS; hydroxypropyl meth
Keywords: ANT; adenine nucleotide translocator; Cyt C; cytochrome C; Cys A; cyclosporine A; FCCP; carbonylcyanide-p-(trifluoromethoxy) phenyl-hydrazone; GCDCA; glycochenodeoxycholic acid; IM; inner membrane; MβCD; methyl-β-cyclodextrin; MMP; mitochondrial membran
Dibromoacetic acid induced Cl.Ly1Â +Â 2/â9 T-cell apoptosis and activation of MAPKs signaling cascades
Keywords: DBA; dibromoacetic acid; FITC; fluorescein isothiocyanate; PI; propidium iodide; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; MMP; mitochondrial membrane potential; Rh123; Rhodamine 123;
Reversal effect of quercetin on multidrug resistance via FZD7/β-catenin pathway in hepatocellular carcinoma cells
Keywords: Quercetin; Hepatocellular carcinoma; Multiple drug resistance; ATP-binding cassette transporters, FZD7/β-catenin pathway; 5-FU; 5-fluorouracil; ABC; ATP-binding cassette; ATP; adenosine triphosphate; ADR; doxorubicin; FZD7; Frizzled homolog protein 7; GV
Hinokiflavone induces apoptosis in melanoma cells through the ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion
Keywords: MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DMSO; dimethyl sulfoxide; PBS; phosphate-buffered saline; FBS; fetal bovine serum; FCM; flow cytometry; ROS; reactive oxygen species; DCFH-DA; 2',7'-dichlorodihydrofluorescein diacetat
Insulin is a potential antioxidant for diabetes-associated cognitive decline via regulating Nrf2 dependent antioxidant enzymes
Keywords: ARE; Nrf2-antioxidant responsive element; CAT; catalase; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; DCFH-DA; 2',7'-dichlorodihydro-fluorescence diacetate; FBS; fetal bovine serum; GSH-Px; glutathione peroxidase; H2O2; hydr
New insights in the in vitro characterisation and molecular modelling of the P-glycoprotein inhibitory promiscuity
Keywords: ADMET; adsorption, distribution, metabolism, excretion, toxicity; DDIs; drug-drug interactions; NME; new molecular entity; Rh123; rhodamine 123; H33342; Hoechst 33,342; P-gp; P-glycoprotein; P-glycoprotein; Drug-drug interactions; Docking; In vitro; Bindi
Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity
Keywords: ABC transporter; Pdr5; Snq2; Cigarette smoke; Caffeine; Saccharomyces cerevisiae; ABC; ATP-binding cassette; AαC; 2-amino-9H-pyrido[23-b]indole; 4- ABP; 4-aminobiphenyl; BaP; benzo(a)pyrene; BLAST; Basic local alignment search tool; BCRP; breast cancer r
In vitro screening of dual flavonoid combinations for reversing P-glycoprotein-mediated multidrug resistance: Focus on antiepileptic drugs
Keywords: Epilepsy; Dual flavonoid combinations; Flavonoids; In vitro studies; P-glycoprotein; Pharmacoresistance; AEDs; Antiepileptic drugs; CBZ; Carbamazepine; CBZ-E; Carbamazepine-10,11-epoxide; CNS; Central nervous system; DMSO; dimethyl sulfoxide; DMEM; Dulbec
Pharmacokinetics, pharmacodynamics and safety profiling of IS01957, a preclinical candidate possessing dual activity against inflammation and nociception
Keywords: Pharmacokinetics; Inflammation; Nociception; Safety pharmacology; IS01957; Para-coumaric acid derivative; p-CA; Para coumaric acid; ADME; Absorption, distribution, metabolism and excretion; CH; Chlorpromazine hydrochloride; PS; Pentobarbital sodium; PBS;
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway
Keywords: BCA; bicinchoninic acid; bFGF; basic fibroblast growth factor; BSA; bovine serum albumin; caspase; cysteine-aspartic acid protease; DCFH-DA; 2â², 7â²-dichloroflurescin- diacetate; DMEM; dulbecco's modified eagle medium; ECM; extracellular matrix; E. col
Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil
Keywords: Uncaria rhynchophylla; Proanthocyanidins; 5-Fluorouracil; Breast cancer; Apoptosis; AAE/g dw; ascorbic acid equivalent/g dry weight; ABTS; 2,20-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid; CI; combination index; CIwt; weighted average; DCF-DA; 2â²,
Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro
Keywords: AMPK; LKB1; Ligustri lucidi Fructus; Liver injury; CCl4; ACC; acetyl-CoA carboxylase; AICAR; aminoimidazole-carboxamide-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; FACS; fluorescence-activated cell sorter; GSH; glutathione; H&E; hematoxylin a
Paeonia japonica root extract protects hepatocytes against oxidative stress through inhibition of AMPK-mediated GSK3β
Keywords: AA; arachidonic acid; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; 4EBP-1; eIF-4E binding protein 1; FACS; fluorescence-a
Anti-angiogenic activities of CRBGP from buccal glands of lampreys (Lampetra japonica)
Keywords: Lamprey; Buccal gland; CRBGP; Anti-angiogenesis; APs; action potentials; BCA; bicinchoninic acid; bFGF; basic fibroblast growth factor; Ca2+; calcium; CAM; chick chorioallantoic membrane; CNG; cyclic nucleotide-gated ion; CRBGP; cysteine-rich buccal gland
Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway
Keywords: ABC; ATP-binding cassette; P-gp; P-glycoprotein; FITC; fluorescein isothiocianate; BafA1; bafilomycin A1; MG132; carbobenzoxy-l-leucyl-l-leucyl-l-leucinal; MG115; carbobenzoxy-l-leucyl-l-leucyl-l-norvalinal; PSI; proteasome inhibitor I; Rh123; rhodamine12
Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions
Keywords: ABCD1; peroxisomal ATP-binding cassette transporter 1; ALDP; adrenoleukodystrophy protein; AMN; adrenomyeloneuropathy; cALD; cerebral ALD; CPA; cyclopiazonic acid; CRC; Ca2Â + retention capacity; DHE; dihydroethidium; DMEM; Dulbecco's modified Eagle's med
Different cell death responses induced by eupomatenoid-5 in MCF-7 and 786-0 tumor cell lines
Keywords: 786-0; human kidney cancer cell line; 7-AAD; 7-aminoactinomycin D; ATP; adenosine triphosphate; DCE; dichloromethanic crude extract; DCF; 2,7-dichlorofluorescein; DCFH; 2,7-dichlorodihydrofluorescein; DCFH-DA; dichlorofluorescin diacetate; DMSO; dimethyl
Toona sinensis (aqueous leaf extracts) induces apoptosis through the generation of ROS and activation of intrinsic apoptotic pathways in human renal carcinoma cells
Keywords: TSL-1; Toona sinensis leaf extract; DCFDA; carboxyl-H2DCFDA; JC-1; 5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethyl benzimidazolylcarbocyanine iodide; MTT; [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyl tetrazolium bromide]; Rh123; Rhodamine 123; Renal cell
SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo
Keywords: chk2; check point kinase 2; CDK1; cyclin-dependent kinase 1; ROS; reactive oxygen species; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; DMSO; dimethyl sulfoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; P
Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter
Keywords: CsA; cyclosporin A; IAA; iodoacetic acid; I/R; ischemia/reperfusion; KRH; Krebs-Ringer-HEPES; MMP; matrix metalloprotease; MCU; mitochondrial calcium uniporter; MPT; mitochondrial permeability transition; OA-Hy; cis-9-octadeconyl-N-hydroxylamide; PI;
Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells
Keywords: Maslinic acid; Triterpenes; Colon cancer cells; Extrinsic apoptotic pathway; CDDO; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FACS; fluorescence-
Oxygen and glucose deprivation (OGD)-induced spreading depression in the Substantia Nigra
Keywords: LT; light transmittance; ÎΨm; mitochondrial membrane potential depolarization; OGD; oxygen-glucose deprivation; Rh123; Rhodamine 123; SD; spreading depression; SN; Substantia Nigra; SNc; Substantia Nigra pars compacta; SNr; Substantia Nigra pars retic
Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP+, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells
Keywords: [Ca2+]i; intracellular calcium concentration; DAT; dopamine transporter; DBH; dopamine-β-hydroxylase; DCFH-DA; 2,7-dichlorofluorescein diacetate; DMEM/F-12; Dulbecco's modified eagle medium nutrient mixture F-12; DMSO; dimethyl sulfoxide; FBS; fetal bovi
Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers
Keywords: ALT; alanine aminotransferase; eNOS; endothelial nitric oxide synthase; FG; fatty liver grafts; hpf; high power field; iNOS; inducible nitric oxide synthase; I/R; ischemia/reperfusion; JNK; c-Jun N-terminal kinase; LG; lean liver grafts; MPT; mitochondria
In vitro antimicrobial activity of nanoconjugated vancomycin against drug resistant Staphylococcus aureus
Keywords: AFM; atomic force microscopy; BHI; brain heart infusion; CFU; colony formation unit; CMC; carboxymethyl chitosan; CMC-EDBE-FA; carboxymethyl chitosan-2,2â²-ethylenedioxy bis ethylamine-folate; CS; chitosan; DAD; disc agar diffusion; d-Ala-d-Ala; d-alanin
Fumonisin B1 inhibits mitochondrial respiration and deregulates calcium homeostasis-Implication to mechanism of cell toxicity
Keywords: [Ca2+]c; cytosolic calcium level; cROS; cytosolic ROS; DPI; diphenylene iodonium; FB1; fumonisin B1; FCCP; carbonyl cyanide p-trifluoromethoxy-phenylhydrazone; GSH; glutathione; HEt; dihydroethidium; IARC; International Agency for Research on Cancer; MCB;
α-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ
Keywords: α-keto acid dehydrogenase multienzyme complex; excitotoxicity; mitochondria; neurodegeneration; reactive oxygen species; succinyl phosphonate; FCCP; carbonyl cyanide 4-trifluoro-methoxyphenylhydrazone; GFAP; glial fibrillary acidic protein; HBSS; Hanks'
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: Relevance to Parkinson's disease
Keywords: 6-OHDA; 6-hydroxydopamine; CHAPS; 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonic acid; CoQ1; ubiquinone; DTT; dithiotreitol; ER; endoplasmic reticulum; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; LBs; Lewy bodies; LC; locus coe
Detection of de- and hyperpolarization of mitochondria of cultured astrocytes and neurons by the cationic fluorescent dye rhodamine 123
Keywords: AntiA; antimycin A; FCCP; carbonyl cyanide 4-(trifluoro-methoxy)phenylhydrazone; FCS; fetal calf serum; F; fluorescence; FU; fluorescence units; GFAP; glial fibrillary acidic protein; glut; glutamate; HBSS; Hanks-buffered salt solution; NeuN; antibody aga
HL-37, a novel anthracene derivative, induces Ca2+-mediated apoptosis in human breast cancer cells
Keywords: Rh123; rhodamine123; PI; propidium iodide; MMP; mitochondrial membrane potential; FCS; fetal calf serum; IC50; concentration resulting in 50% inhibition of cell growth; MTT; 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium bromide; [Ca2+]i; intracellular f
Acrolein-induced cell death in PC12 cells: Role of mitochondria-mediated oxidative stress
Keywords: ROS; reactive oxygen species; PD; Parkinson's disease; AD; Alzheimer's disease; HNE; 4-hydroxynonenal; NAC; N-acetylcysteine; CsA; cyclosporin A; DCFH2-DA; dichlorofluorescein-diacetate; Rh123; Rhdamine 123; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt
Role of Bcl-2 family of proteins in mediating apoptotic death of PC12 cells exposed to oxygen and glucose deprivation
Keywords: OGD; oxygen and glucose deprivation; DMEM; Dulbecco's modified Eagle's medium; Rh123; 2-(6-Amino-3-imino-3H-xanthen-9-yl) benzoic acid methyl ester; Ischemic stroke; Neuronal cell death; Homodimers;
MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-d-glucuronate)
Keywords: ABC transporter; ATP-binding cassette transporter; ACNU; 3-[(4-amino-2-methyl-5-pyrimidinyl) methyl]-1-(2-chloroethyl)-1-nitrosourea; ADM; adriamycin; AG-A; agosterol A; azidoAG-A; [125I] 11-azidophenyl agosterol A; AZT; azidothymidine; BSO; buthionine su