Keywords: کیناز وابسته به Rho; ABP; actin-binding protein; ADF; actin-depolymerizing factor; Aip1; actin-interacting protein 1; Arp; actin-related proteins; CAR; coxsakievirus and adenovirus receptor; CD; Crohn's disease; CeD; celiac disease; EM; electron microscopy; ER; endoplasmic re
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Keywords: کیناز وابسته به Rho; BAK; BCL-2 antagonist killer; BAX; BCL-2 associated X protein; CDK1; cyclin dependent kinase 1; CLDN-6; claudin-6; CM; cardiomyocyte; CPE; Clostridium perfringens endotoxin; GPX2; glutathione peroxidase-2; GSH; glutathione; GSR; glutathione reductase; GSS
Keywords: کیناز وابسته به Rho; BBB; blood-brain barrier; RBE4; rat brain microvascular endothelial cells; HLG; hypoxia/low glucose; FITC-dextran; fluorescein isothiocyanate-dextran; HIF-1α; hypoxia inducible factor-1alpha; VEGF; vascular endothelial growth factor; TJ; tight junction
Keywords: کیناز وابسته به Rho; Mouse Model; Development; Calcium Signaling; Phosphorylation; ACh; acetylcholine; cGMP; guanosine 3â²,5â²-cyclic monophosphate; CTR; control; ICC; interstitial cells of Cajal; LC17; 17-kilodalton myosin light chain; MHC; myosin heavy chain; MLCK; myosin
Naringin attenuates MLC phosphorylation and NF-κB activation to protect sepsis-induced intestinal injury via RhoA/ROCK pathway
Keywords: کیناز وابسته به Rho; CLP; cecal ligation and puncture; LPS; lipopolysaccharide; MPO; myeloperoxidase; RhoA; Ras homolog gene family, member A; ROCK; Rho-associated kinase; NF-κB; nuclear factor-kappa B; MLCK; myosin light chain kinase; MLC; myosin light chain; Naringin; Seps
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: کیناز وابسته به Rho; AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
Necl-4 enhances the PLCγ-c-Raf-MEK-ERK pathway without affecting internalization of VEGFR2
Keywords: کیناز وابسته به Rho; Endocytosis; Endothelial cells; Signaling; VEGF; VEGFR2; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; ERK; extracellular signal-regulated kinase; HUVECs; human umbilical vein endothelial cells; MEK; mitogen-activated protein kinase/ERK kinase; m
Fluid shear stress applied by orbital shaking induces MG-63 osteosarcoma cells to activate ERK in two phases through distinct signaling pathways
Keywords: کیناز وابسته به Rho; FSS; fluid shear stress; PI3-kinase; phosphoinositide-3-kinase; Rho kinase; Rho-associated kinase; Mechanoresponse; Fluid flow; Shear stress; Osteoblast; Orbital shaking;
Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats
Keywords: کیناز وابسته به Rho; BBB; blood-brain-barrier; BDA; biotinylated dextran amine; CST; corticospinal tract; DAPI; 4,6-diamino-2-phenyl indole; ET-1; endothelin-1; GABA; Gamma-aminobutyric acid; KCC2; K+-Clâ-co-transporter 2; LSD; least significant difference; MAG; myelin-as
Original ArticleUp-regulation of Rho-associated kinase 1/2 by glucocorticoids promotes migration, invasion and metastasis of melanoma
Keywords: کیناز وابسته به Rho; Glucocorticoid; Melanoma; Migration; Metastasis; Rho-associated kinase; AKT; GC; glucocorticoid; GR; glucocorticoid receptor; Dex; dexamethasone; CORT; corticosterone; ROCK; Rho-associated kinase; CHX; cycloheximide; MMP; matrix metalloproteinase; TIMP; t
Carbon black aggregates cause endothelial dysfunction by activating ROCK
Keywords: کیناز وابسته به Rho; Carbon black; Aggregate; Endothelial dysfunction; Rho-associated kinase;
Role of Runx2 in breast cancer-mediated bone metastasis
Keywords: کیناز وابسته به Rho; Runx2; runt-related transcription factor 2; BRC; breast cancer gene; HER; herceptin; ER; estrogen; PR; progesterone; ECM; extra cellular matrix; EMT; epithelial mesenchymal transition; JAK/STAT; Janus Kinase; NFκB; nuclear factor kappa-B; MMP; matrix met
Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer
Keywords: کیناز وابسته به Rho; GC; gastric cancer; CEA; carcinoembryonic antigen; FASU; fasudil; FTICR; fourier transform ion cyclotron resonance; MALDI-MSI; matrix-assisted laser desorption/ionization mass spectrometry imaging; MAPK; mitogen-activated protein kinase; MLC; myosin light
Anti-glycan antibodies halt axon regeneration in a model of Guillain Barrè Syndrome axonal neuropathy by inducing microtubule disorganization via RhoA-ROCK-dependent inactivation of CRMP-2
Keywords: کیناز وابسته به Rho; GBS; Guillain Barrè Syndrome; DRGn; dorsal root ganglion neurons; MTs; microtubules; DRG; dorsal root ganglion; GC; growth cone; CRMP-2; collapsing response mediator protein 2; intraperitoneally; IP; IgG; immunoglobulin G; tubulin GFP; green fluorescent
Rho-associated kinase inhibitors promote the cardiac differentiation of embryonic and induced pluripotent stem cells
Keywords: کیناز وابسته به Rho; Rho-associated kinase; Cardiac differentiation; Embryonic stem cells; Hematopoietic differentiation; Induced pluripotent stem cells;
Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction
Keywords: کیناز وابسته به Rho; afferent arteriole; angiotensin II; diphosphorylation; endothelin-1; myosin regulatory light chain; Rho-associated kinase;
Regulation of cell-matrix adhesion by OLA1, the Obg-like ATPase 1
Keywords: کیناز وابسته به Rho; OLA1; Obg-like ATPase 1; FAs; focal adhesions; FAK; focal adhesion kinase; ECM; extracellular matrix; ROCK; Rho-associated kinase; F-actin; filamentous actin; LIMKs; Lim family kinases; TESK; testicular protein kinases; pFAK(Y397); Tyr 397 phosphorylated
Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death
Keywords: کیناز وابسته به Rho; Dopamine; Neuroprotection; Neuroinflammation; Microglia; Parkinson; Rho; LME; l-leucine methyl ester; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-metil-4-fenil-1,2,3,6 tetrahidropiridine; PD; Parkinson's disease; ROCK; Rho-associated Kinase; TH; tyrosine h
Low-dose combination of Rho kinase and L-type Ca2+ channel antagonists for selective inhibition of depolarization-induced sustained arterial contraction
Keywords: کیناز وابسته به Rho; Nifedipine (PubChem CID: 4485); Fasudil (PubChem CID: 3547); Verapamil (PubChem CID: 62969); L-type Ca2+ channels; Rho-associated kinase; Arterial vasospasm; Depolarization;
Kamolonol suppresses angiotensin II-induced stress fiber formation and cellular hypertrophy through inhibition of Rho-associated kinase 2 activity
Keywords: کیناز وابسته به Rho; Ang II; angiotensin II; ROCK; Rho-associated kinase; IMAP; immobilized metal affinity for phosphochemicals; TR-FRET; time-resolved fluorescence resonance energy transfer; MYPT; myosin phosphatase; MLC; myosin light chain; DMEM; Dulbecco's modified Eagle
G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade
Keywords: کیناز وابسته به Rho; CNK1; connector enhancer of KSR-1; DGKθ; diacylglycerol kinase θ; EGF; epidermal growth factor; GIT; GRK-interacting protein; GPCR; G protein-coupled receptor; GRK; GPCR kinase; KSR-1; kinase suppressor of ras-1; MAPK; mitogen-activated protein kinase;
Associations between the Rho kinase-1 catalytic and PH domain regulatory unit
Keywords: کیناز وابسته به Rho; Rho-associated kinase; ROCK; Docking; PH domain
Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics
Keywords: کیناز وابسته به Rho; ECM; extracellular matrix; CAFs; carcinoma-associated fibroblasts; RMFs; reduction mammoplasty fibroblasts; HMECs; human mammary epithelial cells; vHMEC; variant HMEC with repressed p16INK4A; DCIS; ductal carcinoma in situ; IDC; invasive ductal carcinoma;
Rho-associated kinase in the gustatory cortex is involved in conditioned taste aversion memory formation but not in memory retrieval or relearning
Keywords: کیناز وابسته به Rho; Insular cortex; Conditioned taste aversion; Long-term memory; Rho-associated kinase;
cGMP-dependent protein kinase I is involved in neurite outgrowth via a Rho effector, rhotekin, in Neuro2A neuroblastoma cells
Keywords: کیناز وابسته به Rho; NO; nitric oxide; cGK; cGMP-dependent protein kinase; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; 8-pCPT-cGMP; 8-(4-chlorophenylthio)-cGMP; RA; all-trans-retinoic acid; LPA; 1-oleoyl lysophosphatidic acid; VASP; vasodilator-st
Critical roles of Rho-associated kinase in membrane blebbing and mitochondrial pathway of apoptosis caused by 1-butanol
Keywords: کیناز وابسته به Rho; ROCK; Rho-associated coiled-coil protein kinase; z-VAD-fmk; N-benzyloxycarbonyl-Val-Ala-Asp(O-Me) fluoromethyl ketone; MLC; myosin light chain; COX IV; cytochrome c oxidase IV; GFP; green fluorescent protein; PI; propidium iodide; Rho-associated kinase; M
Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists
Keywords: کیناز وابسته به Rho; BSA; bovine serum albumin; C; carboxyl; Cx; connexin; Cx43; connexin43; DG; deoxyglucose; ET; endothelin; ERK; extracellular signal-regulated kinase; G; GTP-binding protein; GJ; gap junction; GJIC; gap junctional intercellular communication; GPCR; GTP-bin
Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil
Keywords: کیناز وابسته به Rho; Rho-associated kinase; Leukocyte; Fasudil;
Changes in cell migration of mesenchymal cells during osteogenic differentiation
Keywords: کیناز وابسته به Rho; Mesenchymal mode; BMP; Y-27632; Osteogenic differentiation; ST2; ROCK; Rho-associated kinase; FAK; focal adhesion kinase; OPN; osteopontin; PTHR; parathyroid hormone receptor; Osx; osterix; OCN; osteocalcin; MLC; myosin light chain;
Stem cell integrins: Implications for ex-vivo culture and cellular therapies
Keywords: کیناز وابسته به Rho; hESC; Human embryonic stem cells; MEK; mitogen activated protein kinase kinase; ERK; extracellular signal-regulated kinase; bFGF; basic fibroblast growth factor; IGF; insulin-like growth factor; ECM; extracellular matrix; VCAM; vascular cell adhesion mole
Human embryonic fibroblasts support single cell enzymatic expansion of human embryonic stem cells in xeno-free cultures
Keywords: کیناز وابسته به Rho; hESC; human embryonic stem cell; iPS; induced pluripotent stem cell; MEF; mouse embryonic fibroblast; SR; serum replacement; XHEF; xeno-free human embryonic fibroblast; XHFF; xeno-free human foreskin fibroblast; ROCK; rho-associated kinase;
Dupuytren's Fibroblast Contractility by Sphingosine-1-Phosphate Is Mediated Through Non-Muscle Myosin II
Keywords: کیناز وابسته به Rho; Dupuytren's disease; non-muscle myosin II; sphingosine-1-phosphate; Rho-associated kinase; myosin light chain kinase
WNT5A induces osteogenic differentiation of human adipose stem cells via rho-associated kinase Rock
Keywords: کیناز وابسته به Rho; adipogenic differentiation; bone tissue engineering; cytoskeleton; human adipose tissue-derived mesenchymal stromal cells; osteogenic differentiation; rho-associated kinase; Wnt5a;
Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase
Keywords: کیناز وابسته به Rho; Phosphatidylserine exposure; Rho proteins; Rho-associated kinase; Flippase; Y27632; H1152;
Rho-associated kinase (ROCK) inhibition reverses low cell activity on hydrophobic surfaces
Keywords: کیناز وابسته به Rho; Hydrophobicity; Rho-associated kinase; Y-27632; Osteoblast; Cell cycle; Migration; Adhesion; Tissue engineering; Biomaterial
The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating μ-opioid receptors
Keywords: کیناز وابسته به Rho; Pain; Cytoskeleton; Rho GTPases; μ-Opioid receptors; Behavior; Bacterial protein toxins; Mice; CNF1; Cytotoxic Necrotizing Factor 1; icv; intracerebroventricular; i.p.; intraperitoneal; i.pl.; intraplantar; MORs; μ-opioid receptors; PAG; periaqueductal
Cystamine prevents ischemia–reperfusion injury by inhibiting polyamination of RhoA
Keywords: کیناز وابسته به Rho; Cystamine; Ischemia–reperfusion injury; Organ preservation solution; Rho-associated kinase; Transglutaminase2
Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation
Keywords: کیناز وابسته به Rho; 16; 23; CABG; coronary artery bypass graft; KCl; potassium chloride; NE; norepinephrine; RA; radial artery; ROCK; Rho-associated kinase; TP receptors; prostanoid receptors selective for thromboxane A2;
Stellate Cell Contraction: Role, Regulation, and Potential Therapeutic Target
Keywords: کیناز وابسته به Rho; Hepatic stellate cell; Contraction; Fibrosis; Pericyte; Rho-associated kinase; Sinusoid
Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats
Keywords: کیناز وابسته به Rho; Hypertension; Pulmonary; Heart defects; Congenital; Smooth muscle cell; Rho-associated kinase; Fasudil
Oligonucleotide array analysis of cyclic tension-responsive genes in human periodontal ligament fibroblasts
Keywords: کیناز وابسته به Rho; Cyclic tension-responsive genes; Oligonucleotide array; Human periodontal ligament fibroblasts; Pathway analysis; Rho-associated kinase