دانلود مقالات ISI درباره S-Adenosylhomocysteine + ترجمه فارسی

Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Keywords: BmMTAN; Brucella melitensis MTAN; INT; 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride; MTA; 5′-methylthioadenosine; MTAN; MTA/SAH nucleosidase; NP-1; nucleoside phosphorylase-1; PDB; Protein Data Bank; PEG; polyethylene glycol; r.m.s.d.

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Hyperhomocysteinemia: Related genetic diseases and congenital defects, abnormal DNA methylation and newborn screening issues

Keywords: AHCY; adenosylhomocysteinase; BHMT; betaine-homocysteine methyl-transferase; Cbl-C; cobalamin C; CHD; congenital heart defects; CTH; cystathionine-γ-lyase; CBS; cystathionine-β-synthase; DS; Down syndrome; hHcy; hyperhomocysteinemia; Hcy; homocysteine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Physiological roles of phosphatidylethanolamine N-methyltransferase

Keywords: AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; CT; CTP:phosphocholine cytidylyltransferase; DHA; docosahexaenoic acid; ER; endoplasmic reticulum; Hcy; homocysteine; LCTαKO; liver-specific CTα knockout; PC; phosphatidylcholine; PE; phospha

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma

Keywords: S-adenosylmethionine; S-adenosylhomocysteine; Acute rejection; Nephrotoxicity; HPLC-MS-MS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolism of selenite to selenosugar and trimethylselenonium in vivo: tissue dependency and requirement for S-adenosylmethionine-dependent methylation

Keywords: Selenium; Selenite; Selenosugar; Trimethylselenonium; Methylation; Liver; S-adenosylhomocysteine; S-adenosylmethionine; Cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Sulfur-based redox alterations in long-lived Snell dwarf mice

Keywords: 5-Me-dCMP; 5-methyl-2′-deoxycytidine-5′-monophosphate; AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; AHC; adenosylhomocysteine hydrolase (adenosylhomocysteinase); BHMT; betainehomocysteinemethyltransferase; CBS; cystathionineβ-synthas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool

Keywords: AD; Alzheimer disease; AIMs; amplification of inter-methylated sites; ALS; amyotrophic lateral sclerosis; ChIP; chromatin immunoprecipitation; CTH; cystathionine γ-lyase; CHARM; comprehensive high-throughput arrays for relative methylation; CBS; cystathi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Dopamine but not l-dopa stimulates neural glutathione metabolism. Potential implications for Parkinson's and other dopamine deficiency states

Keywords: l-dopa; l-3,4-dihydroxyphenylalanine; AADC; aromatic l-amino acid decarboxylase; BH4; tetrahydrobiopterin; ROS; reactive oxygen species; GSH; reduced glutathione; GSSG; glutathione disulphide; FBS; foetal bovine serum; DOPAC; 3,4-dihydroxyphenylacetic aci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis

Keywords: HCC; hepatocellular carcinoma; ASH; alcoholic steatohepatitis; MDD; methyl deficient diet; SAM; S-adenosylmethionine; MAT; methionine adenosyltransferase; SAH; S-adenosylhomocysteine; SAHH; SAH hydroxylase; GSH; reduced glutathione; BHMT; betaine-homocyst

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia

Keywords: Homocysteine; B vitamins deficiency; Protein methylation; S-adenosylhomocysteine; H3R8 methylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A687V EZH2 is a gain-of-function mutation found in lymphoma patients

Keywords: DLBCL; diffuse large B-cell lymphoma; CPM; counts per minute; GCB; germinal Center B-cell-like; H3K27; histone H3 lysine 27; NHL; non-Hogdkin lymphoma; PKMT; protein lysine methyltransferase; PRC2; Polycomb Repressive Complex 2; SAM; S-adenosylmethionine;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Dyrk1a activates antioxidant NQO1 expression through an ERK1/2-Nrf2 dependent mechanism

Keywords: DYRK1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a; SAHH; S-adenosylhomocysteine hydrolase; NQO1; NAD(P)H:quinone oxidoreductase-1; Hcy; homocysteine; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; CBS; cystathionine beta s

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Original Full Length ArticleThe association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures

Keywords: S-adenosylhomocysteine; S-adenosylmethionine; Homocysteine; Osteoporosis; Fractures;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate

Keywords: GNMT; glycine N-methyltransferase; AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; 5-CH3-H4PteGlu1; 5-methyltetrahydropteroyl monoglutamate; 5-CH3-H4Pte-Glu5; 5-methyltetrahydropteroyl pentaglutamate; Glycine N-methyltransferase; Folate; Cry

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A liquid chromatography mass spectrometry method for the measurement of cystathionine β-synthase activity in cell extracts

Keywords: CBS; cystathionine β-synthase; Hcy; homocysteine; Cysta; cystathionine; SAM; S-adenosylmethione; EDTA; ethylenedinitrilotetraacetic acid; PLP; pyridoxal-5-phosphate; SAH; S-adenosylhomocysteine; Cystathionine β-synthase; Homocystinuria; Liquid chromatog

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Catalytic promiscuity of a bacterial α-N-methyltransferase

Keywords: Dha; dehydroalanine; Dhb; dehydrobutyrine; Avi-Cys; S-[(Z)-2-aminovinyl]-cysteine; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; NRMT; N-terminal RCC1 methyltransferase; MCMC; Markov chain Monte Carlo; SPPS; solid phase peptide synthesis; DMF; d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine

Keywords: Homocysteine; S-Adenosylhomocysteine; NADPH oxidase; Endothelial cells;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

6′-Oxa analogs of S-adenosylhomocysteine

Keywords: S-Adenosylhomocysteine; Aristeromycin; Neplanocin; Schöllkopf auxiliary;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: Decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk

Keywords: ALT; Alanine aminotransferase; BHMT; betaine-homocysteine S-methyltransferase; HCU; classical homocystinuria; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase; GNMT; glycine N-methyltransferase; Hcy; homocysteine; IL-1b; interleukin-1beta;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria

Keywords: Ac-Met sulfoxide; N-α-acetyl-l-methionine sulfoxide; ALP; alkaline phosphatase; ALT; alanine aminotransferase; APTT; activated partial thromboplastin time; AST; aspartate aminotransferase; BUN; blood urea nitrogen; CE-MS; capillary electrophoresis-ma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus

Keywords: SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; MTases; Methyltransferases; RFM; Rossmann-Fold Methyltransferases; ITC; isothermal titration calorimetry; CTAB; cetyltrimethylammonium bromide; Small molecule methyltransferase; Antibiotic resistance

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cancers and the NSD family of histone lysine methyltransferases

Keywords: NSD; nuclear receptor binding SET domain; HMTase; Histone Methyl Transferase; AdoMet; S-Adenosylmethionine; AdoHcy; S-Adenosylhomocysteine; Transcription factor; Histone lysine methyl transferase; NSD1; NSD2/MMSET/WHSC1; NSD3/WHSC1L1; Epigenetic cancer th

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetics in neurodegeneration: A new layer of complexity

Keywords: AD; Alzheimer's disease; PD; Parkinson's disease; Aβ; amyloid-β; SN; substantia nigra; APP; amyloid precursor protein; EOAD; early-onset Alzheimer's disease; LOAD; late-onset Alzheimer's disease; SNP; several single nucleotide polymorphisms; MZ; monozyg

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

S-Adenosylhomocysteine enhances DNA damage through increased β-amyloid formation and inhibition of the DNA-repair enzyme OGG1b in microglial BV-2 cells

Keywords: S-Adenosylhomocysteine; β-Amyliod; DNA damage; 8-oxoG-DNA glycosylases I; Hypomethylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Copper and homocysteine in cardiovascular diseases

Keywords: Copper; Homocysteine; Ceruloplasmin; Endothelium; Heart; Blood vessel; ADMA; Asymmetric dimethyl-arginine; BHMT; Betaine:homocysteine methyltransferase; CBS; Cystathionine β-synthase; CCO; Cytochrome c oxidase; CGL; Cystathionine γ-lyase; Cu; Copper; DR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleImpaired homocysteine transsulfuration is an indicator of alcoholic liver disease

Keywords: ALD; alcoholic liver disease; HCY; homocysteine; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; MS; methionine synthase; BHMT; betaine homocysteine methyltransferase; DMG; dimethylglycine; MAT; methionine adenosyl transferase; SAHH; S-adenosylhom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Pyridine salvage and nicotinic acid conjugate synthesis in leaves of mangrove species

Keywords: NaAD; nicotinic acid adenine dinucleotide; NaG; nicotinic acid N-glucoside; NaMN; nicotinic acid mononucleotide; NMN; nicotinamide mononucleotide; NR; nicotinamide riboside; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; UDPG; UDP-glucose; Avicen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The logic of the hepatic methionine metabolic cycle

Keywords: AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; AHC; adenosylhomocysteinase; BHMT; betaine homocysteine S-methyltransferase; CBS; cystathionine β-synthase; GSH; glutathione; GNMT; glycine-N-methyltransferase; Hcy; homocysteine; MATI/II; III

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

Keywords: ALT; Alanine aminotransferase; aPTT; activated partial thromboplastin time; BHMT; betaine-homocysteine S-methyltransferase; HCU; classical homocystinuria; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase; DMG; dimethylglycine; ER; endoplas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Temporal study of acetaminophen (APAP) and S-adenosyl-l-methionine (SAMe) effects on subcellular hepatic SAMe levels and methionine adenosyltransferase (MAT) expression and activity

Keywords: S-adenosyl-l-methionine; Acetaminophen; Hepatotoxicity; S-adenosylhomocysteine; Methionine adenosyltransferase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The kidney is the major site of S-adenosylhomocysteine disposal in humans

Keywords: atherosclerosis; epigenetics; homocysteine; methionine; methylation; S-adenosylhomocysteine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Proteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed rats

Keywords: Alcohol; Liver; Betaine; Proteomics; S-adenosylhomocysteine; S-adenosylmethionine; Carbonic anhydrase-III; Redox stress; Isoaspartate; Protein isoaspartyl methyltransferase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters

Keywords: S-Adenosylhomocysteine; β-Amyloid; Presenilin 1; Hypomethylation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Exogenous folate ameliorates ethanol-induced brain hyperhomocysteinemia and exogenous ethanol reduces taurine levels in chick embryos

Keywords: DTT; Dithiotreitol; EtOH; Ethanol; EDTA; Ethylenediamine-tetraacetic acid; 10-FTHF DH; Formyltetrahydrofolate dehydrogenase; HEPES; N-[2-hydroxyethyl]piperazine-N′ [2-ethanesulfonic acid]; HoCys; Homocysteine; SAH; S-adenosylhomocysteine; SAM; S-adenosy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Biochemical and structural characterization of 5′-methylthioadenosine nucleosidases from Arabidopsis thaliana

Keywords: AdoMet; S-adenosyl-methionine; AtMTAN1; Arabidopsis thaliana MTAN1; AtMTAN2; Arabidopsis thaliana MTA/SAH nucleosidase; EcMTAN; E. coli MTA/SAH nucleosidase; MTAN; 5′-methylthioadenosine nucleosidase; MTAP; 5′-methylthioadenosine phosphorylase; MTR; 5

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues

Keywords: S-Adenosylmethionine; S-Adenosylhomocysteine; Mass spectrometry; Liquid chromatography; Mouse tissues;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Birth Prevalence of Homocystinuria in Central Europe: Frequency and Pathogenicity of Mutation c.1105C>T (p.R369C) in the Cystathionine Beta-Synthase Gene

Keywords: CBS; Cystathionine beta-synthase; CHO; Chinese hamster ovary; PAGE; Polyacrylamide gel electrophoresis; PBS; Phosphate buffered saline solution; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; SDS; Sodium dodecyl sulfate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone

Keywords: Homocysteine; Osteoporosis; Bone; S-adenosylhomocysteine; S-adenosylmethionine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients

Keywords: Cardiovascular disease; Chronic kidney disease; Homocysteine; S-adenosylhomocysteine; S-adenosylmethionine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia

Keywords: ALL; acute lymphoblastic leukemia; CH2-THF; 5,10-methylenetetrahydrofolate; DDH; double distilled water; DHF; dihydrofolate; DHFR; dihydrofolate reductase; dTMP; deoxythymidine monophosphate; dTTP; deoxythymidine triphosphate; dUMP; deoxyuridine monophosp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains

Keywords: Hyperglycemia-induced; Membrane lipid peroxidation; Homocysteine; S-adenosylmethionine; S-adenosylhomocysteine; Chick; Brain;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains

Keywords: Ethanol-induced; Homocysteine; S-adenosylmethionine; S-adenosylhomocysteine; Glycine; Caspase-3; Chick; Brain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Methylation status in healthy subjects with normal and high serum folate concentration

Keywords: Folate; S-adenosylmethionine; S-adenosylhomocysteine; Methylation; Extracellular superoxide dismutase gene

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A universal competitive fluorescence polarization activity assay for S-adenosylmethionine utilizing methyltransferases

Keywords: Fluorescence polarization; Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Catechol-O-methyltransferase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury

Keywords: L-FABP; liver fatty acid binding protein; GST; glutathione S-transferase; CYP2E1; cytochrome P450 2E1; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; MCD; methionine and choline deficient; ROS; reactive oxygen species; PPARα; peroxisome prolifer

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

A simple rapid immunoassay for S-adenosylhomocysteine in plasma

Keywords: S-adenosylhomocysteine; Immunoassay; Plasma; Vascular disease; Human

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease

Keywords: Alzheimer's disease; S-Adenosylhomocysteine; Phospholipid; Polyunsaturated fatty acid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Synergistic effects of S-adenosylhomocysteine and homocysteine on DNA damage in a murine microglial cell line

Keywords: S-adenosylhomocysteine; Homocysteine; DNA damage; DNA hypomethylation; Reactive oxygen species; Synergy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: Effects on protein-l-isoaspartyl methyltransferase activity

Keywords: Alcohol; S-Adenosylhomocysteine; Betaine; Methylation; Protein damage; Liver; Protein-l-isoaspartyl methyltransferase; S-Adenosylmethionine; Isoaspartyl residues

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway

Keywords: Alcohol; S-adenosylhomocysteine; Betaine; Methylation; Apoptosis; Liver; Phosphatidylethanolamine methyltransferases; S-adenosylmethionine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه