Keywords: توکسین عقرب; Electrophysiology; Ion channel; Scorpion toxin; Structure;
مقالات ISI توکسین عقرب (ترجمه نشده)
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Keywords: توکسین عقرب; Scorpion; Venom; Neurotoxin; Neuropeptide; Ion channels; AC50; toxin concentration for activation to 50%; Cav; voltage-gated calcium channel; EC50; half maximal effective concentration; ED50; median effective dose; ER; endoplasmic reticulum; IC50; half ma
Keywords: توکسین عقرب; Androctonus mauretanicus; Buthus occitanus; Scorpion venom; Antivenom; Polyclonal; Scorpion toxin; ED50; Chick biventer cervicis method; Myotoxicity; Neurotoxicity; Lethality;
Keywords: توکسین عقرب; Bayesian inference; Evolution; Phylogenetics; Scorpion toxin
Keywords: توکسین عقرب; κ-Hefutoxin 1; Voltage-gated potassium channel; Scorpion toxin; Synthetic analogs; Amino acid deletion; Subtype selectivity; Acm; acetamidomethyl; CD; circular dichroism; Fmoc; 9-fluorenylmethoxycarbonyl; Hef-1; κ-hefutoxin 1; MALDI-TOF-MS; matrix assis
Keywords: توکسین عقرب; Human scFv; In vitro maturation; Scorpion toxin; aa; amino acid(s); CDR; complementarity determining region (s); C. limpidus; Centruroides limpidus limpidus Karsh; Cll1 and Cll2; toxins 1 and 2 from Centruroides limpidus limpidus venom; C. noxius; Centru
Keywords: توکسین عقرب; Biodiversity; Ion-channel; Functional effect; Scorpion toxin; Structural features;
Keywords: توکسین عقرب; HelaTx1; Voltage-gated potassium channel; Scorpion toxin; Synthetic analog; Amino acid deletion; Amino acid insertionCD, circular dichroism; Fmoc, 9-fluorenylmethoxycarbonyl; HefuTx1, κ-hefutoxin 1; MALDI-TOF-MS, matrix assisted laser desorption/ionizatio
Venoms of Centruroides and Tityus species from Panama and their main toxic fractions
Keywords: توکسین عقرب; Amino acid sequence; Centruroides; Chromatographic separation; Gene cloning; Lethality test; Scorpion toxin; Tityus;
Homology modeling and docking of AahII-Nanobody complexes reveal the epitope binding site on AahII scorpion toxin
Keywords: توکسین عقرب; Nanobody; Scorpion toxin; Sequence pattern; Molecular modeling; Molecular docking;
KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity
Keywords: توکسین عقرب; Ion channel; Molecular dynamics; Peptides; Potassium channel; Neurotoxin; Scorpion toxin; AgTx2; agitoxin-2; CaV; voltage-gated calcium channel; ChTx; charybdotoxin; CSα/β; cysteine-stabilized α/β motif; CSα/α; cysteine-stabilized α/α motif; CSTEV
Discovery of three toxin peptides with Kv1.3 channel and IL-2 cytokine-inhibiting activities from Non-Buthidae scorpions, Chaerilus tricostatus and Chaerilus tryznai
Keywords: توکسین عقرب; Chaerilidae; Kv1.3 channel; Scorpion toxin; IL-2; Potential immunoregulatory peptide;
Pi5 and Pi6, two undescribed peptides from the venom of the scorpion Pandinus imperator and their effects on K+-channels
Keywords: توکسین عقرب; Amino acid sequence; Ion-channel; K+-channel blocker; Pandinus imperator; Scorpion toxin;
Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms
Keywords: توکسین عقرب; Antivenom; Centruroides; Heterologous expression; Immunogen; Recombinant protein; Scorpion toxin;
The roles of conserved aromatic residues (Tyr5 and Tyr42) in interaction of scorpion toxin BmK AGP-SYPU1 with human Nav1.7
Keywords: توکسین عقرب; BmK; Buthus martensii Karsch; Lqq; Leiurus quinquestriatus quinquestriatus; Bot; Buthus occitanus tunetanus; ODO; dontobuthus doriae; SBFI; sodium-binding benzofuran isophthalate; VGSC; voltage-gated sodium channel; CHS; conserved hydrophobic surface; DRG
Transcriptomic analysis of the venom glands from the scorpion Hadogenes troglodytes revealed unique and extremely high diversity of the venom peptides
Keywords: توکسین عقرب; Scorpion venom peptide; Venomics; Hadogenes troglodytes; Transcriptome; Scorpion toxin; Venom composition;
Role of individual disulfide bridges in the conformation and activity of spinoxin (α-KTx6.13), a potassium channel toxin from Heterometrus spinifer scorpion venom
Keywords: توکسین عقرب; Scorpion toxin; Voltage-gated potassium channel; Synthetic analog; Disulfide bond formation; Cysteine-stabilized α/β scaffold; Acm; acetamidomethyl; CSαβ scaffold; cysteine-stabilized α/β scaffold; DCM; dichloromethane; DIEA; N,N-diisopropylethylami
Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus
Keywords: توکسین عقرب; Amino acid sequence; Centruroides; Ion-channel; Scorpion toxin
SjAPI-2 is the first member of a new neurotoxin family with Ascaris-type fold and KCNQ1 inhibitory activity
Keywords: توکسین عقرب; Scorpion toxin; Structural fold; KCNQ1;
Solid phase synthesis, NMR structure determination of α-KTx3.8, its in silico docking to Kv1.x potassium channels, and electrophysiological analysis provide insights into toxin-channel selectivity
Keywords: توکسین عقرب; Scorpion toxin; NMR; Solid phase synthesis; Potassium channel inhibitor; Docking; TEVC method;
A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms
Keywords: توکسین عقرب; Voltage-gated sodium channel; Scorpion toxin; Tityus serrulatus; Bell-shaped modulation; Ion channel modulator; Binding site;
Unique diversity of the venom peptides from the scorpion Androctonus bicolor revealed by transcriptomic and proteomic analysis
Keywords: توکسین عقرب; Scorpion toxin; Androctonus bicolor; Venom peptide; Transcriptomic and proteomic analysis; Venom composition; Ion channels;
Kv1.3 potassium channel-blocking toxin Ctri9577, novel gating modifier of Kv4.3 potassium channel from the scorpion toxin family
Keywords: توکسین عقرب; Scorpion toxin; Gating modifier; Channel blocker;
AGAP, a new recombinant neurotoxic polypeptide, targets the voltage-gated calcium channels in rat small diameter DRG neurons
Keywords: توکسین عقرب; Calcium channel; Scorpion toxin; AGAP; Whole-cell patch clamp; Dynamic function;
Interaction of the scorpion toxin discrepin with Kv4.3 channels and A-type K+ channels in cerebellum granular cells
Keywords: توکسین عقرب; A-type currents; Discrepin; Heterologous expression; K+ channel; Scorpion toxin;
A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells
Keywords: توکسین عقرب; Bidimensional gel; Cellular events; Mass spectrometry; Proteomic analysis; Scorpion toxin;
Scorpion toxins for the reversal of BoNT-induced paralysis
Keywords: توکسین عقرب; Botulinum neurotoxin; Scorpion toxin; Bioterrorism; Aminopyridine; Phrenic nerve hemidiaphragm;
Expression and characterization of a novel scorpine-like peptide Ev37, from the scorpion Euscorpiops validus
Keywords: توکسین عقرب; Euscorpiops validus; Scorpion toxin; Ev37; Kv1.3 channel;
OcyKTx2, a new K+-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum
Keywords: توکسین عقرب; OcyKTx2; Scorpion toxin; Shaker B K+-channel; hKv1.3; lymphocyte; Opisthacanthus cayaporum;
Characterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity
Keywords: توکسین عقرب; Antibacterial; Australia; cDNA library; Scorpion toxin; Urodacus yaschenkoi; Venom;
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
Keywords: توکسین عقرب; Scorpion toxin; Androctonus crassicauda; Cytotoxicity; Apoptosis; Immunization; Monoclonal antibodies;
Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K+ channel toxins
Keywords: توکسین عقرب; Adaptive evolution; hERG channels; Maximum likelihood; Mutational experiments; Scorpion toxin
Two dyad-free Shaker-type K+ channel blockers from scorpion venom
Keywords: توکسین عقرب; Scorpion toxin; BmP02; BmP03; Mesobuthus martensii; Two-electrode voltage clamp
Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda
Keywords: توکسین عقرب; A. crassicauda; Androctonus crassicauda; α-NaScTxs; alpha sodium channel toxins; β-NaScTxs; beta sodium channel toxins; HPLC; high performance liquid chromatography; Nav1.1-1.6; voltage-dependent sodium channels 1.1-1.6; TFA; trifluroacetic acid; TS
Effects of a toxin isolated from Tityus bahiensis scorpion venom on the hippocampus of rats
Keywords: توکسین عقرب; Scorpion toxin; Tityus bahiensis; Neurotransmitters; Microdialysis; Cytosolic calcium;
Turkish scorpion Buthacus macrocentrus: General characterization of the venom and description of Bu1, a potent mammalian Na+-channel α-toxin
Keywords: توکسین عقرب; Buthacus macrocentrus; Na+-channel; Sequence analysis; Scorpion toxin
Interacting sites of scorpion toxin ErgTx1 with hERG1 K+ channels
Keywords: توکسین عقرب; Alanine scanning; Erg channel; Heterologous expression; K+-channel; Scorpion toxin; 3D-modeling;
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): The first member of a new κ-KTX subfamily
Keywords: توکسین عقرب; Scorpion toxin; Voltage-gated potassium channel; Electrophysiology; Patch clamp; cDNA; Heterometrus laoticus
Expression and characterization of recombinant kurtoxin, an inhibitor of T-type voltage-gated calcium channels
Keywords: توکسین عقرب; C; cysteine; CD; circular dichroism; IPTG; isopropyl β-d-thiogalactoside; MALDI-TOF MS; matrix-assisted laser desorption/ionization-time of flight mass spectrometry; NMR; nuclear magnetic resonance; PCR; polymerase chain reaction; RP-HPLC; reverse-phase
Solution structure of a short-chain insecticidal toxin LaIT1 from the venom of scorpion Liocheles australasiae
Keywords: توکسین عقرب; ICK; inhibitory cystine knot; CSα/β; cystine-stabilized α-helix/β-sheet; Inhibitory cystine knot fold; LaIT1; Nuclear magnetic resonance; Scorpion toxin; Solution structure;
Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion
Keywords: توکسین عقرب; Antibody; Human scFv; Phage display; Scorpion toxin; Tityus serrulatus;
Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function
Keywords: توکسین عقرب; Alanine scanning; Erg channel; Heterologous expression; K+-channel; Scorpion toxin; 3D-modeling
ImKTx88, a novel selective Kv1.3 channel blocker derived from the scorpion Isometrus maculates
Keywords: توکسین عقرب; ImKTx88; Isometrus maculates; Scorpion toxin; Kv1.3 channel;
Characterization of three “Birtoxin-like” toxins from the Androctonus amoreuxi scorpion venom
Keywords: توکسین عقرب; Birtoxin; Scorpion toxin; Sodium channel
Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus
Keywords: توکسین عقرب; Cuba; Gene cloning; Ion-channel; Scorpion toxin; Rhopalurus junceus;
Location of the analgesic domain in Scorpion toxin BmK AGAP by mutagenesis of disulfide bridges
Keywords: توکسین عقرب; Scorpion toxin; rBmK AGAP; Disulfide bonds; Analgesic activity; Mutants
Intrahippocampal injection of TsTX-I, a beta-scorpion toxin, causes alterations in electroencephalographic recording and behavior in rats
Keywords: توکسین عقرب; Scorpion toxin; TsTx-I; Veratridine; Hippocampus; Seizure; Electrographic record
Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels
Keywords: توکسین عقرب; Drosotoxin; Drosomycin; Scorpion toxin; Defensin; Venomous arthropod
BmKCT toxin inhibits glioma proliferation and tumor metastasis
Keywords: توکسین عقرب; Scorpion toxin; BmKCT; Gliomas; Proliferation; Metastasis; Targeting; In vivo
Envenomation by the Scorpion Tityus breweri in the Guayana Shield, Venezuela: Report of a Case, Efficacy and Reactivity of Antivenom, and Proposal for a Toxinological Partitioning of the Venezuelan Scorpion Fauna
Keywords: توکسین عقرب; scorpionism; Tityus; Tityus breweri; scorpion venom; scorpion toxin; Guayana; Venezuela