Keywords: صفحات سالخورده; Ach; acetylcholine; AChE; cholinesterase; AD; Alzheimer disease; AMT; adsorptive mediated transcytosis; APP; amyloid precursor protein; ARND; age related neurodegenerative disorders; ALS; amyotrophic lateral sclerosis; BBB; blood brain barrier; CMT; carri
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Keywords: صفحات سالخورده; Aβ; beta-amyloid peptide; AAV; adeno-associated virus; ABAD; amyloid-beta-binding alcohol dehydrogenase; AD; Alzheimer's disease; ALP; autophagy-lysosome pathways; Apaf-1; apoptic protease-activating factor 1; APP; amyloid precursor protein; AICD; APP in
Keywords: صفحات سالخورده; Alzheimer's disease; Senile plaques; Amyloid-β; LRP-1; Angiopep; In vivo imaging; AD animal model;
Keywords: صفحات سالخورده; Dementia; Senile plaques; Neurofibrillary tangles; Tau protein; Beta-amyloid; Image data;
Keywords: صفحات سالخورده; Alzheimer's disease; Amyloid-β; β-secretases; γ-secretases; Computer-Aided Drug Design; AD; Alzheimer's disease; Aβ1-40; beta-Amyloid isoform 40 amino acids in length; Aβ1-42; beta-Amyloid isoform 42 amino acids in length; NMDA; N-Methyl-d-aspart
Keywords: صفحات سالخورده; Cerebral amyloid angiopathy; Amyloid β; Intracerebral hemorrhage; Senile plaques; Neurofibrillary tangles
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Keywords: صفحات سالخورده; 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell
Plasma β-amyloid1-42 reference values in cognitively normal subjects
Keywords: صفحات سالخورده; Aβ; Amyloid β; AD; Alzheimer's disease; Aβ1-42; β-Amyloid1-42; Aβ1-40; β-Amyloid1-40; ELISA; Enzyme-linked Immunosorbent Assay; SPs; senile plaques; APP; Amyloid Protein Precursor; PET; Positron Emission Tomography; CSF; cerebrospinal fluid;
High-glucose induces tau hyperphosphorylation through activation of TLR9-P38MAPK pathway
Keywords: صفحات سالخورده; DM; diabetes mellitus; DE; diabetic encephalopathy; AD; Alzheimer's disease; NFTs; neurofibrillary tangles; SPs; senile plaques; Aβ; amyloid β-protein; TLR9; toll-like receptor 9; P38MAPK; P38mitogen-activated protein kinase; MAP; microtubule-associated
Electrochemical studies of tau protein-iron interactions-Potential implications for Alzheimer's Disease
Keywords: صفحات سالخورده; CD; circular dichroism spectroscopy; CV; cyclic voltammetry; DPV; differential pulse voltammetry; GSK3β; Glycogen synthase kinase 3-β; Lip-NHS; Lipoic acid N-hydroxysuccinimide ester; NFTs; neurofibrillary tangles; n-tau; native tau; p-tau; phosphoryl
Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's disease
Keywords: صفحات سالخورده; Amyloid; Cerebral amyloid angiopathy; Primate; Prion; Seeding; Tauopathy; Senile plaques;
Cyanidin 3-O-β-glucopyranoside activates peroxisome proliferator-activated receptor-γ and alleviates cognitive impairment in the APPswe/PS1ÎE9 mouse model
Keywords: صفحات سالخورده; AD; Alzheimer's disease; Cy3G; cyanidin 3-O-β-glucopyranoside; Aβ25-35; beta-amyloid 25-35; PAP mouse; APPswe/PS1ÎE9 mouse; PPARγ; peroxisome proliferator-activated receptor-γ; SPs; senile plaques; H2O2; hydrogen peroxide; CNS; central nervous sy
Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients
Keywords: صفحات سالخورده; ACO1; acotinase 1; AD; Alzheimer's disease; ANCOVA; univariate analysis of co-variance; APP; amyloid-beta precursor protein; Aβ; amyloid-beta; CDR; Clinical Dementia Rating; Cp; ceruloplasmin; CPO; Cp oxidase activity; eQTLs; expression quantitative trai
Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult
Keywords: صفحات سالخورده; Alzheimer's disease; Clinical trial failures; Neurotoxic soluble oligomers; Soluble ABeta amyloid; Correlation of soluble oligomers with cognitive decline; Synapses; Cognitive decline; Autopsies; Senile plaques; Interrelationship of senile plaque amyloid
Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress conditions
Keywords: صفحات سالخورده; AD; Alzheimer's disease; SPs; senile plaques; NFTs; neurofibrillary tangles; CAA; cerebrovascular amyloid angiopathy; Aβ; amyloid-β peptides; sHsp; small heat shock protein; SpHsp16.0; sHsp from fission yeast Schizosaccharomyces pombe; Amyloid-β; Amy
Tau protein phosphatases in Alzheimer's disease: The leading role of PP2A
Keywords: صفحات سالخورده; AD; Alzheimer's disease; NFT; neurofibrillary tangles; PHF; paired helical filaments; SP; senile plaques; APP; apolipoprotein; PP1; protein phosphatase-1; PP2A; protein phosphatase-2A; PP2B; protein phosphatase-2B; PP5; protein phosphatase-5; PTEN; phosph
Tau protein kinases: Involvement in Alzheimer's disease
Keywords: صفحات سالخورده; AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep
β-Amyloid peptide (1–40) in the brain reaches the nasal cavity via a non-blood pathway
Keywords: صفحات سالخورده; Alzheimer's disease; Nasal cavity; β-Amyloid; Diagnosis; Senile plaques
Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric β-amyloid 1-42-induced neurotoxicity
Keywords: صفحات سالخورده; AD; Alzheimer's disease; Aβ; β-amyloid peptide; APP; amyloid precursor protein; SPs; senile plaques; NFTs; neurofibrillary tangles; ROS; reactive oxygen species; COSs; chitosan oligosaccharides; Aβ42; β-amyloid fragments 1-42; HFIP; 1,1,1,3,3,3-hexafl
Existence of different types of senile plaques between brain and spinal cord of TgCRND8 mice
Keywords: صفحات سالخورده; Senile plaques; Alzheimer’s disease; Spinal cord and glial reaction; TgCRND8 mice
Correlation of Aβ deposition in the nasal cavity with the formation of senile plaques in the brain of a transgenic mouse model of Alzheimer's disease
Keywords: صفحات سالخورده; Alzheimer's disease; Nasal cavity; Beta amyloid peptide; Transgenic mouse model; Senile plaques
Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice
Keywords: صفحات سالخورده; Aβ; Oligomers; Protofibrils; Senile plaques; Dendrites; Synapses; Toxicity;
Pyroglutamate-Aβ 3 and 11 colocalize in amyloid plaques in Alzheimer's disease cerebral cortex with pyroglutamate-Aβ 11 forming the central core
Keywords: صفحات سالخورده; Aβ; Amyloid beta; AD; Alzheimer's disease; N; amino; APP; amyloid precursor protein; BACE 1; beta-site amyloid precursor protein cleaving enzyme 1; QC; glutaminyl cyclase; HPLC; high pressure liquid chromatography; KO; knock out; AβpE3; pyrolyzed Aβ3-x
PIB binding in aged primate brain: Enrichment of high-affinity sites in humans with Alzheimer's disease
Keywords: صفحات سالخورده; Alzheimer's disease; Aβ; Benzothiazole; β-Amyloid; Cerebral amyloid angiopathy; Imaging; Nonhuman primates; Pittsburgh Compound B; Senile plaques;
Mass spectrometric detection of quinolinic acid in microdissected Alzheimer's disease plaques
Keywords: صفحات سالخورده; Quinolinic acid; Alzheimer's disease; Senile plaques; Hippocampus; Laser capture microdissection; Neuroinflammation
Microvascular pathology in the aging human brain: Evidence that senile plaques are sites of microhaemorrhages
Keywords: صفحات سالخورده; Alzheimer's disease; Microvasculature; Senile plaques; Microhaemorrhage; Haem; Collagen IV; Fibrinogen; Capillary; β-Amyloid; von Willebrand factor;
Cathepsin D-mediated proteolysis of apolipoprotein E: Possible role in Alzheimer’s disease
Keywords: صفحات سالخورده; cathepsin E; immunohistopathology; senile plaques; neurofibrillary tangle; ApoEAD, Alzheimer’s disease; apoE, apolipoprotein E; BACE, β-site amyloid precursor protein cleavage enzyme; catD, cathepsin D; catE, cathepsin E; DPPC, dipalmitoylphosphatidylchol
Metales de transición y enfermedad de Alzheimer
Keywords: صفحات سالخورده; Enfermedad de Alzheimer; Placas seniles; Péptido β-amiloide; Metales de transición; Alzheimer's disease; Senile plaques; Amyloid-β peptide; Transition metals;
The expression of calcium/calmodulin-dependent protein kinase II-α in the hippocampus of patients with Alzheimer's disease and its links with AD-related pathology
Keywords: صفحات سالخورده; Degenerative disease; Alzheimer's miscellaneous; Alzheimer's disease; Hippocampus; Calcium/calmodulin-dependent protein kinase II-α; Hyperphosphorylated tau; β-Amyloid; Senile plaques;
Alzheimer's disease with and without cerebral infarcts
Keywords: صفحات سالخورده; Alzheimer disease; Dementia; Cerebrovascular lesions; Mixed dementia; Cerebral infarct; Aged; Pathology; Cognitive decline; Disease progression; Diagnosis; Clinicopathological study; Temporal lobe; Hippocampus; Senile plaques; Neurofibrillary tangles;
Learning and memory as a function of age in Down syndrome: A study using animal-based tasks
Keywords: صفحات سالخورده; AD; Alzheimer's disease; DNMP; delayed non match to position; DNMS; delayed non match to sample; DMR; Dementia Questionnaire for Persons with Mental Retardation; DS; Down syndrome; FSIQ; full score intelligence quotient; ITI; intertrial interval; NFT; neu
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
Keywords: صفحات سالخورده; AD; Alzheimer's disease; Aβ; amyloid β-protein; 3R; three-repeat tau; E; exon; 4R; four-repeat tau; FTDP-17; frontotemporal dementia and parkinsonism linked to chromosome 17; IR; inter-repeat; GSK-3β; glycogen synthase kinase-3β; MT; microtubule; MAP;