Metales de transición y enfermedad de Alzheimer

In this context, it has been shown that transition metals such as copper, iron and zinc, which accumulate in SP, can interact with the Aβ peptide, promoting amyloid aggregation and the formation of reactive oxygen species. Therefore, the interaction between transition metals and the Aβ peptide may partially explain the neuronal and oxidative damage detected in the brains of patients with AD.