Keywords: کمبود شدید مصدوم; HHC; Human Hepatocellular Carcinoma; LCSLC; sliver cancer stem-like cells; TRPV2; Transient Receptor Potential Vanilloid-type 2 channel; TRP; Transient Receptor Potential; SCID; severe combined immunodeficiency; ALDH1; aldehyde dehydrogenase 1; GFP; green
مقالات ISI کمبود شدید مصدوم (ترجمه نشده)
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Keywords: کمبود شدید مصدوم; Flow cytometry; Intracellular protein; Monoclonal antibody; Primary immunodeficiency disease; Surface protein; ADA; adenosine deaminase; ALPS; autoimmune lymphoproliferative syndrome; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrop
Keywords: کمبود شدید مصدوم; T1DM; Type 1 diabetes mellitus; EDS; Search E-Resources; IGF1; insulin-like growth factor 1; NOD; non-obese diabetic; G6Pase; glucose-6-phosphatase; HGF; hepatocyte growth factor; SCID; severe combined immunodeficiency; BTC; betacellulin; Ngn3; Neurogenin
Keywords: کمبود شدید مصدوم; Gene therapy; Omenn syndrome; autoimmunity; lentiviral vector; Rag genes; AIRE; Autoimmune regulator; BAFF; B cell-activating factor; BM; Bone marrow; GT; Gene therapy; HSCT; Hematopoietic stem cell transplantation; Linâ; Lineage negative; LV; Lentivi
Keywords: کمبود شدید مصدوم; CTLs; CD8+ T lymphocytes; ELISA; enzyme-linked immunosorbent assay; ITP; immune thrombocytopenia; IBD; inflammatory bowel disease; OA; osteoarthritis; PGRN; progranulin; rPGRN; recombinant progranulin; RA; rheumatoid arthritis; SLE; systemic lupus erythem
Keywords: کمبود شدید مصدوم; DC; dendritic cell; tolDCs; tolerogenic dendritic cells; PD-1; programmed cell death 1; PD-L1/PD-L2; programmed cell death ligand 1/2; 17XNL; nonlethal 17X strains; BCG; Mycobacterium bovis Bacillus Calmette Guérin; BMDCs; bone marrow-derived dendritic c
Keywords: کمبود شدید مصدوم; Primary immunodeficiency; malignancy; tumor predisposition; immune surveillance; pre-existing condition; ALL; Acute lymphoblastic leukemia; ALPS; Autoimmune lymphoproliferative syndrome; AT; Ataxia teleangiectasia; CHH; Cartilage-hair hypoplasia; CID; Com
Keywords: کمبود شدید مصدوم; Combined immunodeficiencies; next-generation DNA sequencing; whole-exome sequencing; targeted gene panel sequencing; AT; Ataxia telangiectasia; BCG; Bacillus Calmette-Guérin; BCGosis; Disseminated BCG infection; CID; Combined immunodeficiency; HIES; Hy
Keywords: کمبود شدید مصدوم; ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob
Keywords: کمبود شدید مصدوم; ACPP; activated cell-penetrating peptide; AFM; atomic force microscopy; AN; angiopeptin; ANP; NP modified with ACPP peptide; APE-1; apurinic endonuclease-1; AU; gold; AUC; area under the curve; AUNP; gold nanoparticles; AUNS; gold nanoshells; BAT; brain a
Keywords: کمبود شدید مصدوم; BSE; bovine spongiform encephalopathy; CAP; CEVEC'samniocyte production; CEF; chicken embryo fibroblast; DNA; deoxyribonucleic acid; EP; European Pharmacopeia; FBS; fetal bovine serum; GCCP; good cell culture practice; GMP; good manufacturing practices; H
Keywords: کمبود شدید مصدوم; ADAM; (a disintegrin and metalloprotease) metallopeptidase; ALPs; alkyl-lysophospholipids; CD24; signal transducer CD24 (glycosylphosphatidylinositol-anchored receptor); CD44; CD44 antigen (receptor for hyaluronic acid); CXCR4; chemokine receptor type 4;
Keywords: کمبود شدید مصدوم; ANXA 1; annexin A1; APA; aminopeptidase A; APN; aminopeptidase N; APP; aminopeptidase P; BBB; blood-brain barrier; CT; computed tomography; CREG1; cellular repressor of E1A-stimulated genes 1; DDL4; delta like ligand 4; DLP; dynamin-1 like protein; Eph-
Keywords: کمبود شدید مصدوم; Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
Keywords: کمبود شدید مصدوم; EPR; enhanced permeability and retention; FDA; food and drug administration; RES; reticuloendothelial system; NFP; nanofiber; 2D; 2-dimensional; 3D; 3-dimensional; ASTM; American Society for Testing and Materials; SCID; severe combined immunodeficiency; Q
Keywords: کمبود شدید مصدوم; Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
TTC7A mutation must be considered in patients with repeated intestinal atresia associated with early inflammatory bowel disease: Two new case reports and a literature review
Keywords: کمبود شدید مصدوم; Tetratricopeptide repeat domain 7A (TTC7A); Graft-versus-host disease (GVHD); Inflammatory bowel disease (IBD); Parenteral nutrition; Severe combined immunodeficiency (SCID); Intestinal atresias; D; day; GVHD; graft-versus-host disease; IBD; inflammatory
Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice
Keywords: کمبود شدید مصدوم; HCV; Glecaprevir; Pibrentasvir; Sofosbuvir; NS5A inhibitor resistance associated variant; P32 deletion; Human hepatocyte chimeric mouse; ASV; asunaprevir; DAAs; Direct-acting antivirals; DCV; daclatasvir; GLE; glecaprevir; HCV; hepatitis C virus; LDV; led
Antiviral T Cells for Adenovirus in the Pretransplant Period: A Bridge Therapy for Severe Combined Immunodeficiency
Keywords: کمبود شدید مصدوم; Severe combined immunodeficiency; Adoptive immunotherapy; Adenovirus; T-lymphocytes;
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria
Keywords: کمبود شدید مصدوم; AUC; area under the curve; BA; bioavailability; CLplasma; plasma clearance; CLint; intrinsic clearance; CYP; cytochrome P450; DCM; dichloromethane; DMF; dimethyl formamide; ED; effective dose; FaSSIF; fasted state simulated intestinal fluid; FeSSIF; fed s
DNA damage, metabolism and aging in pro-inflammatory T cells
Keywords: کمبود شدید مصدوم; EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5â²-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;
CD45 in human physiology and clinical medicine
Keywords: کمبود شدید مصدوم; AD; Alzheimer disease; ALL; acute lymphocytic leukemia; APC; antigen presenting cell; BMHSC; bone marrow hematopoietic stem cell; CLL; chronic lymphocytic leukemia; DLBCL; diffuse large B cell lymphoma; IS; immunological synapse; MGL; macrophage galactose
Possible use of Punica granatum (Pomegranate) in cancer therapy
Keywords: کمبود شدید مصدوم; 27HC; 27-hydroxycholesterol; 8-OHdG; 8-hydroxy-2â² -deoxyguanosine; 8-oxodG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; APC; adenomatous polyposis coli; AR; androgen receptors; AOM; azoxymethane; ATP; adenosine triphosphate; B(a)P; benzo(a)pyrene; Bad; Bcl-2
Hypericin affects cancer side populations via competitive inhibition of BCRP
Keywords: کمبود شدید مصدوم; ABC transporters; ATP-binding cassette transporters; ALDH; aldehyde dehydrogenase; BCRP; breast carcinoma resistance protein; CDH1; cadherin 1 gene encoding E-cadherin; CSLCs; cancer stem-like cells; DEAB; N,N-diethylaminobenzaldehyde; EDTA; ethylenediami
Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice
Keywords: کمبود شدید مصدوم; Tumor Progression; Immune Cell Migration; Anti-tumor Immune Response; Infiltration; ChIP; chromatin immunoprecipitation; CM; conditioned medium; HUVEC; human umbilical vein endothelial cell; IHC; immunohistochemistry; MLC; monocyte lineage cell; MVD; micr
Cholangiocytes: Cell transplantation
Keywords: کمبود شدید مصدوم; ALDH; Aldehydedehydrogenase; CD; Cluster differentiation; EGF; Epidermal growth factor; EpCAM; Epithelial cell adhesion molecule; ECM; Extracellular matrix; FGF; Fibroblast growth factor; GMP; Good manufacturing practice; G-CSF; Granulocyte colony-stimula
T-cell receptor αβ+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency
Keywords: کمبود شدید مصدوم; Primary immunodeficiency; haploidentical; mismatched unrelated; hematopoietic stem cell transplantation; CD3+ T-cell receptor αβ+ cell depletion; aGvHD; Acute graft-versus-host disease; ATG; Anti-thymocyte globulin; CMV; Cytomegalovirus; CTL; Cytotoxic
In vitro models for immunogenicity prediction of therapeutic proteins
Keywords: کمبود شدید مصدوم; Therapeutic protein; Immunogenicity assessment; In vitro model; Subcutaneous injection; Injection site reactions; ADAs; antidrug antibodies; ALN; artificial lymph node; APCs; antigen presenting cells; ASCs; adipose-derived stem/stromal cells; DCs; dendrit
Combined immunodeficiency and atopy caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11)
Keywords: کمبود شدید مصدوم; Caspase activation and recruitment domain family member 11; combined immunodeficiency; hypogammaglobulinemia; nuclear factor κB; cytokine secretion; T-cell repertoire; T-cell mitogen and antigen responses; autoimmunity; asthma; eczema and food allergies;
β-Lapachone and its iodine derivatives cause cell cycle arrest at G2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells
Keywords: کمبود شدید مصدوم; ctDNA; Calf thymus DNA; CTL; Negative control; DAF-FM diacetate; 4-amino-5-methylamino-2'-,7'-difluofluorescein diacetate; DCF-DA; 2',7'-dichlorodihydrofluorescein diacetate; DMSO; Dimethyl sulfoxide; DOX; Doxorubicin; FBS; Fetal bovine serum; FSC; Fo
Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders
Keywords: کمبود شدید مصدوم; Ataxia-telangiectasia; Cernunnos-XLF deficiency; DNA repair disorders; DNA ligase IV deficiency; hematopoietic stem cell transplantation; Nijmegen breakage syndrome; aGvHD; Acute graft-versus-host disease; AT; Ataxia-telangiectasia; ATG; Anti-thymocyte gl
Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis
Keywords: کمبود شدید مصدوم; Farmers' children; nonmicrobial; N-glycolylneuraminic acid; airway inflammation; colitis; anti-inflammatory; BAL; Bronchoalveolar lavage; CMAH; CMP-Neu5Ac hydroxylase; Foxp3; Forkhead box protein 3; Neu5Ac; N-acetylneuraminic acid; Neu5Gc; N-glycolylneura
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts
Keywords: کمبود شدید مصدوم; Tumor Progression; Epigenetic Modification; Chromatin Remodeling; Mechanotransduction; α-SMA; α-smooth muscle actin; CCl4; carbon tetrachloride; ChIP-qPCR; chromatin immunoprecipitation-quantitative polymerase chain reaction; CM; conditioned medium; c
Thymus transplantation for complete DiGeorge syndrome: European experience
Keywords: کمبود شدید مصدوم; DiGeorge syndrome; athymia; thymus transplantation; AIRE; Autoimmune regulator; ATG; Antithymocyte globulin; cDGS; Complete DiGeorge syndrome; CHARGE; Coloboma, heart defects, atresia choanae, retardation of growth and development, genital abnormalities,
CD11c+ T-bet+ memory B cells: Immune maintenance during chronic infection and inflammation?
Keywords: کمبود شدید مصدوم; ABCs; Age-related B cells; AID; activation-induced cytidine deaminase; BCR; B cell receptor; DT; diphtheria toxin; EMLA; E. muris-like agent; FcR; Fc receptor; GC; germinal center; HCl; hairy cell leukemia; IOE; Ixodes ovatus ehrlichia; LPS; lipopolysacch
Non-CSCs nourish CSCs through interleukin-17E-mediated activation of NF-κB and JAK/STAT3 signaling in human hepatocellular carcinoma
Keywords: کمبود شدید مصدوم; Cancer stem cell; Non-cancer stem cell; IL-17E; IL-17RB; Human hepatocellular carcinoma; CSCs; cancer stem cells; non-CSCs; non- cancer stem cells; IL; interleukin; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; JAK; Janus kinases; STAT; s
Tumour stromal morphology impacts nanomedicine cytotoxicity in patient-derived xenografts
Keywords: کمبود شدید مصدوم; DXR; doxorubicin; EPR; enhanced permeability and retention; MVD; microvessel density; PDTX; patient-derived tumour xenograft (also referred to as: explant tumour); SCID; severe combined immunodeficiency; SDARS; Spatial Distribution of Apoptosis Relative t
Immunodeficiency-related vaccine-derived poliovirus (iVDPV) cases: A systematic review and implications for polio eradication
Keywords: کمبود شدید مصدوم; AFP; acute flaccid paralysis; aVDPV; ambiguous vaccine-derived poliovirus; cVDPV; circulating vaccine-derived poliovirus; GNI; gross national income; GPEI; Global Polio Eradication Initiative; IPV; inactivated polio vaccine; iVDPV; immunodeficiency-relate
Hypermethylation in gastric cancer
Keywords: کمبود شدید مصدوم; 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge
The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts
Keywords: کمبود شدید مصدوم; ANOVA; analysis of variance; BLI; bioluminescence imaging; CA4; combretastatin A-4; CA4P; combretastatin A-4 phosphate; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; FAK; focal adhesion kinase; FDA; Federal Drug Adm
Macrophages and galectin 3 play critical roles in CVB3-induced murine acute myocarditis and chronic fibrosis
Keywords: کمبود شدید مصدوم; VM; viral myocarditis; CVB3; coxsackievirus B3; DCM; dilated cardiomyopathy; HF; heart failure; MOI; multiplicity of infection; LipClod; liposome encapsulated clodronate; Gal-3; galectin 3; dpi; days post-infection; Lgals3â/â; Gal-3-deficient mice; WT
The inclusion of ADA-SCID in expanded newborn screening by tandem mass spectrometry
Keywords: کمبود شدید مصدوم; ADA-SCID; severe combined immunodeficiency due to adenosine-deaminase defect; SCID; severe combined immunodeficiency; ADA; adenosine deaminase; dAdo; 2-deoxyadenosine; ERT; enzyme replacement therapy; Ado; adenosine; TRECs; T-cell receptor excision circle
Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer
Keywords: کمبود شدید مصدوم; AMP; adenosine monophosphate; ATP; adenosine triphosphate; BRCA1; breast cancer 1; BRCA2; breast cancer 2; eNAMPT; extracellular nicotinamide phosphoribosyltransferase; ERK; extracellular signal-regulated kinases; iNAMPT; intracellular nicotinamide phosph
Nephronectin is upregulated in acute and chronic hepatitis and aggravates liver injury by recruiting CD4 positive cells
Keywords: کمبود شدید مصدوم; Npnt; nephronectin; OPN; osteopontin; Con A; concanavalin A; DDC; 3,5-diethoxycarbonyl-1,4-dihydro-collidine; NKT; natural killer T cells; BD; bile duct; PV; portal vein; CV; central vein; ECM; extracellular matrix; HTVi; hydrodynamic tail vein injection;
A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections
Keywords: کمبود شدید مصدوم; ALT; alanine aminotransferase; GCV; ganciclovir; HBV; hepatitis B virus; HCV; hepatitis C virus; HSA; human serum albumin; HSVtk; herpes simplex virus type-1 thymidine kinase; IFN; interferon; PegIFN-alpha; pegylated interferon-alpha; RI; repopulation ind
LukS-PV induces mitochondrial-mediated apoptosis and G0/G1 cell cycle arrest in human acute myeloid leukemia THP-1 cells
Keywords: کمبود شدید مصدوم; PVL; Panton-Valentine leukocidin; AML; acute myeloid leukemia; Cyclin; cell cycle arrest regulatory protein; CTCL; cutaneous T-cell lymphoma; LtxA; leukotoxin; PMNs; polymorphonuclear leukocytes; FBS; fetal bovine serum; MTS; 3-(4,5-dimethylthiazol-2-yl)-
Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the 99mTc(CO)3+ core
Keywords: کمبود شدید مصدوم; Boc; t-butyloxycarbonyl; BSA; bovine serum albumin; Cys; cysteine; DIEA; N,N-diisopropylethylamine; DIC; diisopropylcarbamide; DMEM; Dulbecco's modified Eagle medium; DMF; dimethylformamide; EDTA; ethylenediaminetetraacetic acid; ESI-MS; electrospray io
Cellular calibrators to quantitate T-cell receptor excision circles (TRECs) in clinical samples
Keywords: کمبود شدید مصدوم; TREC; Tâcell receptor excision circle; TCR; Tâcell receptor; DBS; dried blood spots; SCID; Severe combined immunodeficiency; HCT; hematopoietic cell transplantation; EBV; Epstein Barr virus; TREC-EBV; Tâcell receptor excision circle-Epstein Barr v
Liposomal paclitaxel formulations
Keywords: کمبود شدید مصدوم; Cr-P; paclitaxel solubilized in Cremophor EL®; DCP; dicetylphosphate; DEPC; dielaidoyl phosphatidyl choline; DLPC; dilauroyl phosphatidyl choline; DLPE; dilauroyl phosphatidyl ethanolamine; DLPG; dilauroyl phosphatidyl glycerol; DLTs; dose-limiting toxic
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma
Keywords: کمبود شدید مصدوم; IgG; immunoglobulin G; mAb; monoclonal antibody; MRP; multidrug resistance protein; PDAC; pancreatic ductal adenocarcinoma; SCID; severe combined immunodeficiency; SD; standard deviation; TUNEL; TdT-mediated dUTP nick end labelling; VEGF; Vascular Endothe